NO315652B1 - Substituerte benzoltienylpiperaziner, deres anvendelse som medikamenter, fremgangsmåter for fremstilling samt farmasöytiske sammensetningerinneholdende disse - Google Patents

Substituerte benzoltienylpiperaziner, deres anvendelse som medikamenter, fremgangsmåter for fremstilling samt farmasöytiske sammensetningerinneholdende disse Download PDF

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Publication number
NO315652B1
NO315652B1 NO19961077A NO961077A NO315652B1 NO 315652 B1 NO315652 B1 NO 315652B1 NO 19961077 A NO19961077 A NO 19961077A NO 961077 A NO961077 A NO 961077A NO 315652 B1 NO315652 B1 NO 315652B1
Authority
NO
Norway
Prior art keywords
fluorobenzo
compound
thien
hydrogen
butyl
Prior art date
Application number
NO19961077A
Other languages
English (en)
Norwegian (no)
Other versions
NO961077L (no
NO961077D0 (no
Inventor
Nicholas Joseph Hrib
John G Jurcak
Abdul E Murtlib
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of NO961077D0 publication Critical patent/NO961077D0/no
Publication of NO961077L publication Critical patent/NO961077L/no
Publication of NO315652B1 publication Critical patent/NO315652B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19961077A 1995-03-17 1996-03-15 Substituerte benzoltienylpiperaziner, deres anvendelse som medikamenter, fremgangsmåter for fremstilling samt farmasöytiske sammensetningerinneholdende disse NO315652B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41381895A 1995-03-17 1995-03-17

Publications (3)

Publication Number Publication Date
NO961077D0 NO961077D0 (no) 1996-03-15
NO961077L NO961077L (no) 1996-09-18
NO315652B1 true NO315652B1 (no) 2003-10-06

Family

ID=23638775

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19961077A NO315652B1 (no) 1995-03-17 1996-03-15 Substituerte benzoltienylpiperaziner, deres anvendelse som medikamenter, fremgangsmåter for fremstilling samt farmasöytiske sammensetningerinneholdende disse

Country Status (23)

Country Link
US (1) US5801176A (cs)
EP (1) EP0732332B1 (cs)
JP (1) JPH093060A (cs)
KR (1) KR100402510B1 (cs)
CN (1) CN1082959C (cs)
AT (1) ATE211137T1 (cs)
AU (1) AU700077B2 (cs)
CA (1) CA2171695A1 (cs)
CZ (1) CZ80496A3 (cs)
DE (1) DE69618050T2 (cs)
DK (1) DK0732332T3 (cs)
ES (1) ES2170177T3 (cs)
HU (1) HUP9600665A3 (cs)
IL (1) IL117519A (cs)
NO (1) NO315652B1 (cs)
NZ (1) NZ286186A (cs)
PL (1) PL182310B1 (cs)
PT (1) PT732332E (cs)
RO (1) RO117453B1 (cs)
RU (1) RU2157371C2 (cs)
SG (1) SG54269A1 (cs)
TW (1) TW328957B (cs)
ZA (1) ZA962075B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703083A (en) * 1996-04-15 1997-12-30 Neurogen Corporation N-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine receptor subtype specific ligands
AU5567000A (en) * 1999-06-24 2001-01-09 Toray Industries, Inc. Alpha1b-adrenergic receptor antagonists
GB0117531D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands
EP1392676B1 (en) * 2001-02-16 2006-12-13 Aventis Pharmaceuticals Inc. Heterocyclic urea derivatives and their use as dopamine d3 receptor ligands
JP4497815B2 (ja) * 2001-02-16 2010-07-07 アベンティス・ファーマスーティカルズ・インコーポレイテツド 新規な複素環式アミド誘導体およびドーパミンｄ３受容体リガンドとしてのその使用
WO2002078669A1 (fr) * 2001-03-30 2002-10-10 Takeda Chemical Industries, Ltd. Solutions medicinales
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
AR055203A1 (es) 2005-08-31 2007-08-08 Otsuka Pharma Co Ltd Derivados de benzotiofeno con propiedades antipsicoticas
CN105985314A (zh) * 2015-02-05 2016-10-05 苏州旺山旺水生物医药有限公司 布瑞哌唑类似物的制备方法
KR20220120625A (ko) * 2019-12-24 2022-08-30 스미토모 파마 가부시키가이샤 지방족 산 아미드 유도체
JP7655885B2 (ja) * 2021-06-30 2025-04-02 住友ファーマ株式会社 脂肪族酸アミド誘導体を含有する医薬組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU577802B2 (en) * 1983-10-17 1988-10-06 Duphar International Research B.V. Blood-pressure lowering piperazine derivatives
ATE81123T1 (de) * 1987-11-20 1992-10-15 Hoechst Roussel Pharma 3-(4(1-substituierte-4-piperazinyl)butyl>-4thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US4968792A (en) * 1989-09-25 1990-11-06 American Home Products Corporation Psychotropic benzisothiazole derivatives
US5143923B1 (en) * 1991-04-29 1993-11-02 Hoechst-Roussel Pharmaceuticals Incorporated Benzoisothiazole-and benzisoxazole-3-carboxamides
RU2024520C1 (ru) * 1991-10-08 1994-12-15 Институт органической химии Уральского отделения РАН 10-метокси-5- метил-6- (1',1'- диоксидо-2'- метахлорфенилазо -3'- гидрокси -4'-метоксибензо(в)тиофен- 7-ил) -5h-3,4,6,7- тетрагидрофуро [4.3.2-q] [3]бензазоцин, обладающий антидепрессивным действием
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
US5240927A (en) * 1992-05-19 1993-08-31 Hoechst-Roussel Pharmaceuticals Incorporated Benzo[β]thiophen-3-yl piperazines as antipsychotic agents
GB9302622D0 (en) * 1993-02-10 1993-03-24 Wellcome Found Heteroaromatic compounds
US5395835A (en) * 1994-03-24 1995-03-07 Warner-Lambert Company Naphthalamides as central nervous system agents
GB9410031D0 (en) * 1994-05-19 1994-07-06 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
PL182310B1 (pl) 2001-12-31
ATE211137T1 (de) 2002-01-15
DK0732332T3 (da) 2002-04-15
RO117453B1 (ro) 2002-03-29
IL117519A0 (en) 1996-07-23
AU700077B2 (en) 1998-12-17
EP0732332B1 (en) 2001-12-19
CZ80496A3 (en) 1996-10-16
CN1082959C (zh) 2002-04-17
ZA962075B (en) 1997-12-31
HU9600665D0 (en) 1996-05-28
PL313251A1 (en) 1996-09-30
HUP9600665A3 (en) 1998-08-28
NO961077L (no) 1996-09-18
JPH093060A (ja) 1997-01-07
RU2157371C2 (ru) 2000-10-10
NO961077D0 (no) 1996-03-15
AU4811396A (en) 1996-09-26
CN1139108A (zh) 1997-01-01
EP0732332A1 (en) 1996-09-18
PT732332E (pt) 2002-06-28
HUP9600665A2 (en) 1997-10-28
DE69618050D1 (de) 2002-01-31
DE69618050T2 (de) 2002-07-11
ES2170177T3 (es) 2002-08-01
KR100402510B1 (ko) 2004-03-18
IL117519A (en) 2000-08-31
SG54269A1 (en) 1998-11-16
TW328957B (en) 1998-04-01
CA2171695A1 (en) 1996-09-18
NZ286186A (en) 1997-07-27
US5801176A (en) 1998-09-01
KR960034201A (ko) 1996-10-22

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