NO315944B1 - CR1 protein for diagnostisk anvendelse in vitro, dets nukleinsyresekvens, rekombinant celle uttrykkende CR1 proteinet og en fremgangsmåte forå rense et CR1 protein - Google Patents

CR1 protein for diagnostisk anvendelse in vitro, dets nukleinsyresekvens, rekombinant celle uttrykkende CR1 proteinet og en fremgangsmåte forå rense et CR1 protein Download PDF

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Publication number
NO315944B1
NO315944B1 NO20000827A NO20000827A NO315944B1 NO 315944 B1 NO315944 B1 NO 315944B1 NO 20000827 A NO20000827 A NO 20000827A NO 20000827 A NO20000827 A NO 20000827A NO 315944 B1 NO315944 B1 NO 315944B1
Authority
NO
Norway
Prior art keywords
protein
lhr
fragment
cdna
fragments
Prior art date
Application number
NO20000827A
Other languages
English (en)
Norwegian (no)
Other versions
NO20000827L (no
NO20000827D0 (no
Inventor
Douglas T Fearon
Lloyd B Klickstein
Winnie W Wong
Gerald R Carson
Michael F Concino
Stephen H Ip
Savvas C Makrides
Jr Henry C Marsh
Original Assignee
Avant Immunotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20000827L publication Critical patent/NO20000827L/no
Application filed by Avant Immunotherapeutics Inc filed Critical Avant Immunotherapeutics Inc
Publication of NO20000827D0 publication Critical patent/NO20000827D0/no
Publication of NO315944B1 publication Critical patent/NO315944B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20000827A 1988-04-01 2000-02-18 CR1 protein for diagnostisk anvendelse in vitro, dets nukleinsyresekvens, rekombinant celle uttrykkende CR1 proteinet og en fremgangsmåte forå rense et CR1 protein NO315944B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17653288A 1988-04-01 1988-04-01
PCT/US1989/001358 WO1989009220A1 (en) 1988-04-01 1989-03-31 THE HUMAN C3b/C4b RECEPTOR (CR1)
US41274589A 1989-09-26 1989-09-26

Publications (3)

Publication Number Publication Date
NO20000827L NO20000827L (no) 1990-11-09
NO20000827D0 NO20000827D0 (no) 2000-02-18
NO315944B1 true NO315944B1 (no) 2003-11-17

Family

ID=26872337

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000827A NO315944B1 (no) 1988-04-01 2000-02-18 CR1 protein for diagnostisk anvendelse in vitro, dets nukleinsyresekvens, rekombinant celle uttrykkende CR1 proteinet og en fremgangsmåte forå rense et CR1 protein

Country Status (14)

Country Link
EP (1) EP0411031B1 (de)
JP (1) JP3484189B2 (de)
CN (2) CN1092712C (de)
AT (1) ATE240973T1 (de)
CA (2) CA1341443C (de)
DE (1) DE68929466T2 (de)
DK (1) DK175699B1 (de)
ES (1) ES2014593A6 (de)
FI (2) FI106316B (de)
IL (1) IL89790A (de)
NO (1) NO315944B1 (de)
SG (1) SG52789A1 (de)
WO (1) WO1989009220A1 (de)
ZA (2) ZA892397B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
WO1991005855A1 (en) * 1989-10-12 1991-05-02 Imutran Limited Modified biological material
US6482404B1 (en) 1989-10-12 2002-11-19 David James White Transplantation of tissue comprising a DNA sequence encoding a homologous complement restriction factor
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US6458360B1 (en) * 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
EP0785273A1 (de) * 1990-11-26 1997-07-23 Genetics Institute, Inc. Gepaarte basische Aminosäuren konvertierendes Enzym und dafür kodierende DNA Sequenz
CA2097825A1 (en) * 1990-12-06 1992-06-07 Henry C. Marsh, Jr. Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity
EP1413587A2 (de) 1991-05-03 2004-04-28 Washington University Modifizierter Regulator des Komplementsystems
EP0649468B1 (de) * 1992-06-24 2000-03-15 AdProTech plc Lösliche derivate des complement type-rezeptors (cr1)
US5456909A (en) * 1992-08-07 1995-10-10 T Cell Sciences, Inc. Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo
WO1994017822A1 (en) * 1993-02-12 1994-08-18 T Cell Sciences, Inc. PULMONARY ADMINISTRATION OF sCR1 AND OTHER COMPLEMENT INHIBITORY PROTEINS
BR9708387A (pt) 1996-03-28 2000-01-04 Genitrix Llc Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada.
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
GB9706950D0 (en) * 1997-04-05 1997-05-21 Chernajovsky Yuti Immune modulation by polypeptides related to CR1
US6664052B1 (en) 1998-07-24 2003-12-16 The Uab Research Foundation Genetic polymorphism in a complement receptor
WO2000005413A1 (en) * 1998-07-24 2000-02-03 Uab Research Foundation Genetic polymorphism in a complement receptor
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
GB9905503D0 (en) 1999-03-10 1999-05-05 Adprotech Plc Novel compound formulations and methods of delivery
EP1738763A1 (de) 2005-06-30 2007-01-03 AVANT Immunotherapeutics, Inc. Verwendung eines Komplement-inhibierenden Proteins zur Behandlung von Rückenmarksverletzungen
SI3028716T1 (sl) 2006-10-10 2021-01-29 Regenesance B.V. Komplementarna inhibicija za izboljšano regeneracijo živcev
CA2744100C (en) 2008-10-21 2020-06-30 The General Hospital Corporation Cell transplantation
KR101809301B1 (ko) 2010-08-06 2018-01-18 더 제너럴 하스피털 코포레이션 두잉 비즈니스 애즈 매사츄세츠 제너럴 하스피털 세포 처리 시스템 및 장치
CN103237557A (zh) 2010-09-15 2013-08-07 赛尔戴克斯治疗公司 用可溶性I型补体受体(sCR1)治疗慢性肾病
EP2632476B1 (de) 2010-10-27 2017-06-14 Celldex Therapeutics, Inc. Verfahren zur verbesserung einer transplantatfunktion unter verwendung des löslichen komplementrezeptors typ i (scr1)
CA2816423A1 (en) 2010-11-02 2012-05-31 Kypha, Inc. Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders
CN102702339B (zh) * 2011-05-24 2013-10-30 华南师范大学 斜带石斑鱼补体c3基因、载体、重组菌株和蛋白及其应用
JP6138815B2 (ja) * 2011-12-01 2017-05-31 エーピー バイオサイエンシーズ， インコーポレイテッド 補体経路およびｖｅｇｆ経路に対するタンパク質インヒビターおよびそれらの使用方法
WO2013082458A1 (en) 2011-12-02 2013-06-06 The Regents Of The University Of California Reperfusion protection solution and uses thereof
CN104293836A (zh) * 2014-06-24 2015-01-21 长沙赢润生物技术有限公司 一种免疫复合物吸附细胞的制作方法
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide
EP3760645A1 (de) * 2019-07-02 2021-01-06 imusyn GmbH & Co. KG Analyse für das blutgruppenantigen dacy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60192948A (ja) * 1984-03-14 1985-10-01 Fuji Photo Film Co Ltd 湿し水不要ネガ型感光性平版印刷版および製版方法
US4672044A (en) * 1984-08-24 1987-06-09 Scripps Clinic & Research Foundation Murine monoclonal antibody combining site to human C3b receptor (CR1)

Also Published As

Publication number Publication date
JP3484189B2 (ja) 2004-01-06
ZA892397B (en) 1989-11-29
EP0411031A4 (en) 1992-02-05
CN1092712C (zh) 2002-10-16
WO1989009220A1 (en) 1989-10-05
JPH04501502A (ja) 1992-03-19
DK234890A (da) 1990-11-30
CA1340866C (en) 1999-12-28
ATE240973T1 (de) 2003-06-15
AU3539489A (en) 1989-10-16
AU647371B2 (en) 1994-03-24
ZA907693B (en) 1992-05-27
FI20002515L (fi) 2000-11-16
EP0411031B1 (de) 2003-05-21
NO20000827L (no) 1990-11-09
CN1053265A (zh) 1991-07-24
CN1036987A (zh) 1989-11-08
EP0411031A1 (de) 1991-02-06
FI115528B (fi) 2005-05-31
FI904842A0 (fi) 1990-10-01
NO20000827D0 (no) 2000-02-18
DK234890D0 (da) 1990-09-28
IL89790A0 (en) 1989-09-28
SG52789A1 (en) 1998-09-28
CN1053924C (zh) 2000-06-28
DE68929466D1 (de) 2003-06-26
ES2014593A6 (es) 1990-07-16
DK175699B1 (da) 2005-01-24
DE68929466T2 (de) 2004-04-01
IL89790A (en) 2002-05-23
FI106316B (fi) 2001-01-15
CA1341443C (en) 2003-10-07

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