NO320574B1 - Polymorf av 5-(4-(2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4-dion-maleinsyresalt, anvendelse og fremgangsmate for fremstilling derav samt farmasoytisk preparat. - Google Patents

Polymorf av 5-(4-(2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4-dion-maleinsyresalt, anvendelse og fremgangsmate for fremstilling derav samt farmasoytisk preparat. Download PDF

Info

Publication number: NO320574B1
Authority: NO; Norway
Prior art keywords: polymorph; compound; polymorph according; diabetes mellitus; polymorphen
Prior art date: 1999-04-23

Application number

NO20015147A

Other languages

English (en)

Norwegian (no)

Other versions

NO20015147D0 (no

NO20015147L (no

Inventor

Robert Gordon Giles

Paul David James Blackler

Christine Marie Browne

Timothy G Coakley

Gillian Morrissey

Original Assignee

Smithkline Beecham Plc

Smithkline Beecham Cork Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-23

Filing date

2001-10-22

Publication date

2005-12-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315461&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO320574(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-04-23 Priority claimed from GBGB9909473.2A external-priority patent/GB9909473D0/en

1999-05-25 Priority claimed from GBGB9912196.4A external-priority patent/GB9912196D0/en

2001-10-22 Application filed by Smithkline Beecham Plc, Smithkline Beecham Cork Ltd filed Critical Smithkline Beecham Plc

2001-10-22 Publication of NO20015147D0 publication Critical patent/NO20015147D0/no

2001-12-17 Publication of NO20015147L publication Critical patent/NO20015147L/no

2005-12-27 Publication of NO320574B1 publication Critical patent/NO320574B1/no

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20015147A 1999-04-23 2001-10-22 Polymorf av 5-(4-(2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4-dion-maleinsyresalt, anvendelse og fremgangsmate for fremstilling derav samt farmasoytisk preparat. NO320574B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9909473.2A GB9909473D0 (en)	1999-04-23	1999-04-23	Novel compounds
GBGB9912196.4A GB9912196D0 (en)	1999-05-25	1999-05-25	Novel pharmaceutical
PCT/GB2000/001520 WO2000064896A1 (en)	1999-04-23	2000-04-19	Polymorph of 5-[4-[2- (n-methyl-n-( 2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt

Publications (3)

Publication Number	Publication Date
NO20015147D0 NO20015147D0 (no)	2001-10-22
NO20015147L NO20015147L (no)	2001-12-17
NO320574B1 true NO320574B1 (no)	2005-12-27

Family

ID=26315461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20015147A NO320574B1 (no)	1999-04-23	2001-10-22	Polymorf av 5-(4-(2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4-dion-maleinsyresalt, anvendelse og fremgangsmate for fremstilling derav samt farmasoytisk preparat.

Country Status (40)

Country	Link
US (2)	US6806280B1 (es)
EP (2)	EP1173435B1 (es)
JP (1)	JP2002543077A (es)
KR (1)	KR100744360B1 (es)
CN (1)	CN1167702C (es)
AP (1)	AP1598A (es)
AR (2)	AR023561A1 (es)
AT (1)	ATE246191T1 (es)
AU (1)	AU765005B2 (es)
BG (1)	BG65485B1 (es)
BR (1)	BR0009932A (es)
CA (1)	CA2370280A1 (es)
CO (1)	CO5170421A1 (es)
CZ (1)	CZ20013800A3 (es)
DE (1)	DE60004196T2 (es)
DK (1)	DK1173435T3 (es)
DZ (1)	DZ3156A1 (es)
EA (1)	EA004541B1 (es)
ES (1)	ES2203453T3 (es)
HK (1)	HK1045153B (es)
HR (1)	HRP20010772B1 (es)
HU (1)	HUP0200931A3 (es)
IL (1)	IL146111A0 (es)
MA (1)	MA25356A1 (es)
MX (1)	MXPA01010821A (es)
MY (1)	MY131973A (es)
NO (1)	NO320574B1 (es)
NZ (1)	NZ515168A (es)
OA (1)	OA11872A (es)
PE (1)	PE20010044A1 (es)
PL (1)	PL351684A1 (es)
PT (1)	PT1173435E (es)
SK (1)	SK286427B6 (es)
TR (1)	TR200103062T2 (es)
TW (1)	TWI283677B (es)
UA (1)	UA67844C2 (es)
UY (1)	UY26121A1 (es)
WO (1)	WO2000064896A1 (es)
YU (1)	YU75301A (es)
ZA (1)	ZA200108719B (es)

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US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726568D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US20020137940A1 (en) *	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
UA67844C2 (uk) *	1999-04-23	2004-07-15	Смітклайн Бічам Плс	Поліморф 5-[4-[2-(n-метил-n-(2-піридил)аміно)етокси]бензил]тіазолідин-2,4-діону солі малеїнової кислоти
EP1903043A1 (en)	1999-04-23	2008-03-26	SmithKline Beecham P.L.C.	Novel pharmaceutical
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
GB0006133D0 (en)	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
US7241895B2 (en)	2000-09-26	2007-07-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
CZ2003864A3 (cs) *	2000-09-26	2004-01-14	Dr. Reddy´S Research Foundation	Nové polymorfní formy 5-[4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl]thiazolidin-2,4-dion-maleátu a způsob jejich přípravy
EP1505066B1 (en) *	2002-04-19	2006-12-06	Faes Farma, S.A.	Polymorph of acid 4-[2-[4-[1-(2-ethoxyethyl)-1h-benzimidazole-2-il]-1-piperidinyl]ethyl]-alpha, alpha-dimethyl-benzeneacetic
GB0307259D0 (en) *	2003-03-28	2003-05-07	Glaxo Group Ltd	Process
EP1468997A3 (en) *	2003-04-18	2004-11-03	CHEMI S.p.A.	Polymorphous forms of rosiglitazone maleate
GB2405403A (en) *	2003-08-29	2005-03-02	Cipla Ltd	Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
EP1709038A2 (en) *	2004-01-28	2006-10-11	Usv Limited	A process for the preparation of 5- 4- 2- n-methyl -n-(2-pyridyl) amino ethoxy phenyl methyl thiaz olidine-2, 4-dione maleate
ITMI20041537A1 (it) *	2004-07-28	2004-10-28	Chemi Spa	Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) *	2005-05-24	2007-09-26	Zentiva, A. S.	Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
US20090076093A1 (en) *	2007-09-14	2009-03-19	Protia, Llc	Deuterium-enriched rosiglitazone
EP2184055A1 (en)	2008-11-07	2010-05-12	LEK Pharmaceuticals d.d.	Process for preparing solid dosage forms of rosiglitazone maleate
JP2010013472A (ja) *	2009-09-09	2010-01-21	Faes Farma Sa	４−［２−［１−（２−エトキシエチル）−１Ｈ−ベンズイミダゾール−２−イル］−１−ピペリジニル］エチル］−α，α−ジメチルベンゼノ酢酸の多形体
JOP20190144A1 (ar)	2016-12-16	2019-06-16	Janssen Pharmaceutica Nv	إيميدازو بيرولو بيريدين كمثبطات لعائلة jak الخاصة بإنزيمات الكيناز
JP7291077B2 (ja)	2016-12-16	2023-06-14	ヤンセンファーマシューティカエヌ．ベー．	Ｊａｋファミリーのキナーゼの低分子阻害物質
TW202016110A (zh)	2018-06-15	2020-05-01	比利時商健生藥品公司	Ｊａｋ激酶家族之小分子抑制劑
MX2023010642A (es)	2021-03-11	2023-11-28	Janssen Pharmaceutica Nv	Lorpucitinib para uso en el tratamiento de trastornos mediados por jak.

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GB9218830D0 (en)	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5741803A (en)	1992-09-05	1998-04-21	Smithkline Beecham Plc	Substituted thiazolidinedionle derivatives
US5478852C1 (en) *	1993-09-15	2001-03-13	Sankyo Co	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
DE4404198A1 (de)	1994-02-10	1995-08-17	Henkel Kgaa	2-Fluor-6-nitroaniline
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US20020137940A1 (en)	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726563D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
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US6613785B2 (en) *	1998-07-21	2003-09-02	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
WO2000064893A2 (en)	1999-04-23	2000-11-02	Smithkline Beecham Plc	Thiazolidinedione derivative and its use as antidiabetic
EP1903043A1 (en)	1999-04-23	2008-03-26	SmithKline Beecham P.L.C.	Novel pharmaceutical
UA67844C2 (uk) *	1999-04-23	2004-07-15	Смітклайн Бічам Плс	Поліморф 5-[4-[2-(n-метил-n-(2-піридил)аміно)етокси]бензил]тіазолідин-2,4-діону солі малеїнової кислоти
CN1277965A (zh)	2000-06-14	2000-12-27	中国医药研究开发中心	盐酸罗格列酮及其应用
CZ2003864A3 (cs)	2000-09-26	2004-01-14	Dr. Reddy´S Research Foundation	Nové polymorfní formy 5-[4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl]thiazolidin-2,4-dion-maleátu a způsob jejich přípravy

2000
- 2000-04-19 UA UA2001117939A patent/UA67844C2/uk unknown
- 2000-04-19 AT AT00920892T patent/ATE246191T1/de not_active IP Right Cessation
- 2000-04-19 TR TR2001/03062T patent/TR200103062T2/xx unknown
- 2000-04-19 PE PE2000000365A patent/PE20010044A1/es not_active Application Discontinuation
- 2000-04-19 PT PT00920892T patent/PT1173435E/pt unknown
- 2000-04-19 EP EP00920892A patent/EP1173435B1/en not_active Expired - Lifetime
- 2000-04-19 NZ NZ515168A patent/NZ515168A/xx unknown
- 2000-04-19 SK SK1492-2001A patent/SK286427B6/sk not_active IP Right Cessation
- 2000-04-19 JP JP2000614248A patent/JP2002543077A/ja active Pending
- 2000-04-19 HR HR20010772A patent/HRP20010772B1/xx not_active IP Right Cessation
- 2000-04-19 CZ CZ20013800A patent/CZ20013800A3/cs unknown
- 2000-04-19 WO PCT/GB2000/001520 patent/WO2000064896A1/en not_active Ceased
- 2000-04-19 IL IL14611100A patent/IL146111A0/xx unknown
- 2000-04-19 DZ DZ003156A patent/DZ3156A1/xx active
- 2000-04-19 AP APAP/P/2001/002330A patent/AP1598A/en active
- 2000-04-19 HU HU0200931A patent/HUP0200931A3/hu unknown
- 2000-04-19 BR BR0009932-5A patent/BR0009932A/pt not_active Application Discontinuation
- 2000-04-19 EP EP02080321A patent/EP1304330A3/en not_active Withdrawn
- 2000-04-19 DE DE60004196T patent/DE60004196T2/de not_active Expired - Fee Related
- 2000-04-19 KR KR1020017013540A patent/KR100744360B1/ko not_active Expired - Fee Related
- 2000-04-19 CO CO00028929A patent/CO5170421A1/es not_active Application Discontinuation
- 2000-04-19 YU YU75301A patent/YU75301A/sh unknown
- 2000-04-19 HK HK02104879.6A patent/HK1045153B/en not_active IP Right Cessation
- 2000-04-19 CA CA002370280A patent/CA2370280A1/en not_active Abandoned
- 2000-04-19 MX MXPA01010821A patent/MXPA01010821A/es active IP Right Grant
- 2000-04-19 PL PL00351684A patent/PL351684A1/xx not_active Application Discontinuation
- 2000-04-19 ES ES00920892T patent/ES2203453T3/es not_active Expired - Lifetime
- 2000-04-19 AR ARP000101862A patent/AR023561A1/es unknown
- 2000-04-19 AR ARP000101867A patent/AR023565A1/es unknown
- 2000-04-19 OA OA1200100276A patent/OA11872A/en unknown
- 2000-04-19 US US10/048,123 patent/US6806280B1/en not_active Expired - Fee Related
- 2000-04-19 CN CNB008091463A patent/CN1167702C/zh not_active Expired - Fee Related
- 2000-04-19 AU AU41308/00A patent/AU765005B2/en not_active Ceased
- 2000-04-19 EA EA200101121A patent/EA004541B1/ru not_active IP Right Cessation
- 2000-04-19 DK DK00920892T patent/DK1173435T3/da active
- 2000-04-21 MY MYPI20001708A patent/MY131973A/en unknown
- 2000-04-24 UY UY26121A patent/UY26121A1/es not_active Application Discontinuation
- 2000-05-11 TW TW089108962A patent/TWI283677B/zh not_active IP Right Cessation
2001
- 2001-10-22 MA MA26378A patent/MA25356A1/fr unknown
- 2001-10-22 NO NO20015147A patent/NO320574B1/no unknown
- 2001-10-23 ZA ZA200108719A patent/ZA200108719B/en unknown
- 2001-11-20 BG BG106121A patent/BG65485B1/bg unknown
2004
- 2004-09-08 US US10/935,939 patent/US20050080114A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HUP0200931A3 (en)	2004-03-29
CZ20013800A3 (cs)	2002-04-17
CO5170421A1 (es)	2002-06-27
NO20015147D0 (no)	2001-10-22
CN1167702C (zh)	2004-09-22
PL351684A1 (en)	2003-06-02
UY26121A1 (es)	2000-12-29
IL146111A0 (en)	2002-07-25
TR200103062T2 (tr)	2002-05-21
MA25356A1 (fr)	2001-12-31
DK1173435T3 (da)	2003-11-24
HRP20010772B1 (hr)	2007-05-31
ATE246191T1 (de)	2003-08-15
US20050080114A1 (en)	2005-04-14
ES2203453T3 (es)	2004-04-16
SK286427B6 (sk)	2008-09-05
PE20010044A1 (es)	2001-03-10
HK1045153B (en)	2004-07-09
WO2000064896A1 (en)	2000-11-02
AR023565A1 (es)	2002-09-04
YU75301A (sh)	2004-07-15
KR20010110797A (ko)	2001-12-13
PT1173435E (pt)	2003-12-31
DE60004196D1 (de)	2003-09-04
EP1173435A1 (en)	2002-01-23
AU4130800A (en)	2000-11-10
HK1045153A1 (en)	2002-11-15
EP1173435B1 (en)	2003-07-30
AP2001002330A0 (en)	2000-12-31
AP1598A (en)	2006-04-26
JP2002543077A (ja)	2002-12-17
AU765005B2 (en)	2003-09-04
CN1356999A (zh)	2002-07-03
HUP0200931A2 (en)	2002-08-28
EP1304330A2 (en)	2003-04-23
HRP20010772A2 (en)	2002-10-31
NO20015147L (no)	2001-12-17
BG65485B1 (bg)	2008-09-30
DE60004196T2 (de)	2004-04-15
US6806280B1 (en)	2004-10-19
BR0009932A (pt)	2002-04-09
MY131973A (en)	2007-09-28
WO2000064896A9 (en)	2001-10-25
AR023561A1 (es)	2002-09-04
SK14922001A3 (sk)	2002-02-05
KR100744360B1 (ko)	2007-07-30
UA67844C2 (uk)	2004-07-15
BG106121A (en)	2002-05-31
EA004541B1 (ru)	2004-06-24
EA200101121A1 (ru)	2002-04-25
TWI283677B (en)	2007-07-11
DZ3156A1 (fr)	2000-11-02
EP1304330A3 (en)	2003-11-19
CA2370280A1 (en)	2000-11-02
OA11872A (en)	2006-03-27
ZA200108719B (en)	2002-06-21
NZ515168A (en)	2004-02-27
MXPA01010821A (es)	2003-09-04

Publication	Publication Date	Title
NO320574B1 (no)	2005-12-27	Polymorf av 5-(4-(2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4-dion-maleinsyresalt, anvendelse og fremgangsmate for fremstilling derav samt farmasoytisk preparat.
NO320589B1 (no)	2005-12-27	Polymorf, anvendelse og fremstilling derav, samt farmasoytisk preparat.
NO317255B1 (no)	2004-09-27	Substituert tiazolidinderivat, fremgangsmate for fremstilling og anvendelse derav
NO320587B1 (no)	2005-12-27	Polymorf, anvendelse og fremstilling derav, samt farmasoytisk preparat.
NO317254B1 (no)	2004-09-27	5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt-hydrat som farmasoytikum
NO317253B1 (no)	2004-09-27	Hydrat av 5-[-4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt
NO320609B1 (no)	2005-12-27	Hydroklorid-hydrat, anvendelse og fremstilling derav, samt farmasoytisk preparat.
NO320573B1 (no)	2005-12-27	Hydroklorid-hydrater, anvendelse og fremstilling derav, samt farmasoytisk preparat.
US7358366B2 (en)	2008-04-15	Thiazolidinedione derivative and its use as antidiabetic
HK1056552A (en)	2004-02-20	Polymorph of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
HK1054021A (en)	2003-11-14	Thiazolidinedione derivative and its use as antidiabetic