NO323448B1 - Hydrokloridsalter av 5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion, fremgangsmate for fremstilling derav samt farmasoytisk preparat omfattende hydrokloridsaltet. - Google Patents

Hydrokloridsalter av 5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion, fremgangsmate for fremstilling derav samt farmasoytisk preparat omfattende hydrokloridsaltet. Download PDF

Info

Publication number: NO323448B1
Authority: NO; Norway
Prior art keywords: hydrochloride; provides; compound; methyl; pyridyl
Prior art date: 2000-03-14

Application number

NO20024307A

Other languages

English (en)

Norwegian (no)

Other versions

NO20024307D0 (no

NO20024307L (no

Inventor

Andrew Simon Craig

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-14

Filing date

2002-09-09

Publication date

2007-05-07

2002-09-09 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2002-09-09 Publication of NO20024307D0 publication Critical patent/NO20024307D0/no

2002-09-09 Publication of NO20024307L publication Critical patent/NO20024307L/no

2007-05-07 Publication of NO323448B1 publication Critical patent/NO323448B1/no

Links

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YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical class C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 title claims description 5
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QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 title description 4
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Obesity (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20024307A 2000-03-14 2002-09-09 Hydrokloridsalter av 5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion, fremgangsmate for fremstilling derav samt farmasoytisk preparat omfattende hydrokloridsaltet. NO323448B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0006133.3A GB0006133D0 (en)	2000-03-14	2000-03-14	Novel pharmaceutical
PCT/GB2001/001131 WO2001068646A1 (en)	2000-03-14	2001-03-14	Hydrochloride salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione

Publications (3)

Publication Number	Publication Date
NO20024307D0 NO20024307D0 (no)	2002-09-09
NO20024307L NO20024307L (no)	2002-09-09
NO323448B1 true NO323448B1 (no)	2007-05-07

Family

ID=9887600

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20024307A NO323448B1 (no)	2000-03-14	2002-09-09	Hydrokloridsalter av 5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion, fremgangsmate for fremstilling derav samt farmasoytisk preparat omfattende hydrokloridsaltet.

Country Status (30)

Country	Link
US (2)	US7074811B2 (cs)
EP (1)	EP1265893B1 (cs)
JP (1)	JP2003527393A (cs)
KR (1)	KR100746813B1 (cs)
CN (1)	CN100516062C (cs)
AP (1)	AP1545A (cs)
AT (1)	ATE302202T1 (cs)
AU (1)	AU777987B2 (cs)
BG (1)	BG65924B1 (cs)
BR (1)	BR0108870A (cs)
CA (1)	CA2403109A1 (cs)
CZ (1)	CZ20023074A3 (cs)
DE (1)	DE60112729T2 (cs)
DK (1)	DK1265893T3 (cs)
DZ (1)	DZ3316A1 (cs)
EA (1)	EA005115B1 (cs)
ES (1)	ES2243458T3 (cs)
GB (1)	GB0006133D0 (cs)
HU (1)	HUP0300158A3 (cs)
IL (2)	IL151425A0 (cs)
MA (1)	MA25658A1 (cs)
MX (1)	MXPA02008972A (cs)
NO (1)	NO323448B1 (cs)
NZ (1)	NZ520910A (cs)
OA (1)	OA12229A (cs)
PL (1)	PL357283A1 (cs)
SK (1)	SK286399B6 (cs)
UA (1)	UA73974C2 (cs)
WO (1)	WO2001068646A1 (cs)
ZA (1)	ZA200207292B (cs)

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US20200155558A1 (en)	2018-11-20	2020-05-21	Boehringer Ingelheim International Gmbh	Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
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US8106111B2 (en) *	2009-05-15	2012-01-31	Eastman Chemical Company	Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions
EA034869B1 (ru)	2009-11-27	2020-03-31	Бёрингер Ингельхайм Интернациональ Гмбх	Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин
MX341025B (es)	2010-05-05	2016-08-04	Boehringer Ingelheim Int Gmbh *	Terapia de combinacion.
PH12012502524A1 (en)	2010-06-24	2014-02-10	Boehringer Ingelheim Int	Diabetes therapy
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EP3517539B1 (en)	2011-07-15	2022-12-14	Boehringer Ingelheim International GmbH	Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes
US9555001B2 (en)	2012-03-07	2017-01-31	Boehringer Ingelheim International Gmbh	Pharmaceutical composition and uses thereof
US20130303554A1 (en)	2012-05-14	2013-11-14	Boehringer Ingelheim International Gmbh	Use of a dpp-4 inhibitor in sirs and/or sepsis
JP6224084B2 (ja)	2012-05-14	2017-11-01	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
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2000
- 2000-03-14 GB GBGB0006133.3A patent/GB0006133D0/en not_active Ceased
2001
- 2001-03-14 ES ES01911921T patent/ES2243458T3/es not_active Expired - Lifetime
- 2001-03-14 MX MXPA02008972A patent/MXPA02008972A/es active IP Right Grant
- 2001-03-14 PL PL01357283A patent/PL357283A1/xx not_active Application Discontinuation
- 2001-03-14 AP APAP/P/2002/002600A patent/AP1545A/en active
- 2001-03-14 JP JP2001567737A patent/JP2003527393A/ja active Pending
- 2001-03-14 CZ CZ20023074A patent/CZ20023074A3/cs unknown
- 2001-03-14 OA OA1200200285A patent/OA12229A/en unknown
- 2001-03-14 US US10/221,686 patent/US7074811B2/en not_active Expired - Fee Related
- 2001-03-14 BR BR0108870-0A patent/BR0108870A/pt not_active IP Right Cessation
- 2001-03-14 SK SK1330-2002A patent/SK286399B6/sk not_active IP Right Cessation
- 2001-03-14 EP EP01911921A patent/EP1265893B1/en not_active Expired - Lifetime
- 2001-03-14 DZ DZ013316A patent/DZ3316A1/fr active
- 2001-03-14 CN CNB018000010A patent/CN100516062C/zh not_active Expired - Fee Related
- 2001-03-14 AU AU40843/01A patent/AU777987B2/en not_active Ceased
- 2001-03-14 UA UA2002097390A patent/UA73974C2/uk unknown
- 2001-03-14 IL IL15142501A patent/IL151425A0/xx unknown
- 2001-03-14 EA EA200200975A patent/EA005115B1/ru not_active IP Right Cessation
- 2001-03-14 KR KR1020027011997A patent/KR100746813B1/ko not_active Expired - Fee Related
- 2001-03-14 NZ NZ520910A patent/NZ520910A/en not_active IP Right Cessation
- 2001-03-14 DK DK01911921T patent/DK1265893T3/da active
- 2001-03-14 HU HU0300158A patent/HUP0300158A3/hu unknown
- 2001-03-14 AT AT01911921T patent/ATE302202T1/de active
- 2001-03-14 DE DE60112729T patent/DE60112729T2/de not_active Expired - Lifetime
- 2001-03-14 WO PCT/GB2001/001131 patent/WO2001068646A1/en not_active Ceased
- 2001-03-14 CA CA002403109A patent/CA2403109A1/en not_active Abandoned
2002
- 2002-08-20 BG BG107012A patent/BG65924B1/bg unknown
- 2002-08-22 IL IL151425A patent/IL151425A/en not_active IP Right Cessation
- 2002-09-09 NO NO20024307A patent/NO323448B1/no not_active IP Right Cessation
- 2002-09-11 ZA ZA200207292A patent/ZA200207292B/en unknown
- 2002-09-12 MA MA26814A patent/MA25658A1/fr unknown
2005
- 2005-07-18 US US11/183,353 patent/US20050267162A1/en not_active Abandoned

Also Published As

Publication number	Publication date
IL151425A0 (en)	2003-04-10
AP1545A (en)	2006-01-12
US20040152901A1 (en)	2004-08-05
HUP0300158A3 (en)	2005-04-28
DZ3316A1 (fr)	2001-09-20
CN100516062C (zh)	2009-07-22
ZA200207292B (en)	2003-05-06
US20050267162A1 (en)	2005-12-01
EA200200975A1 (ru)	2003-02-27
KR100746813B1 (ko)	2007-08-06
NO20024307D0 (no)	2002-09-09
KR20020079998A (ko)	2002-10-21
WO2001068646A1 (en)	2001-09-20
EP1265893B1 (en)	2005-08-17
AU4084301A (en)	2001-09-24
CA2403109A1 (en)	2001-09-20
MXPA02008972A (es)	2003-02-10
BG107012A (bg)	2003-04-30
EA005115B1 (ru)	2004-10-28
SK13302002A3 (sk)	2003-02-04
BG65924B1 (bg)	2010-05-31
BR0108870A (pt)	2002-12-17
MA25658A1 (fr)	2002-12-31
DE60112729T2 (de)	2006-06-08
HK1052502A1 (en)	2003-09-19
NO20024307L (no)	2002-09-09
ES2243458T3 (es)	2005-12-01
HUP0300158A2 (en)	2003-05-28
DE60112729D1 (de)	2005-09-22
DK1265893T3 (da)	2005-11-14
CN1358184A (zh)	2002-07-10
JP2003527393A (ja)	2003-09-16
PL357283A1 (en)	2004-07-26
AU777987B2 (en)	2004-11-11
CZ20023074A3 (cs)	2003-02-12
GB0006133D0 (en)	2000-05-03
US7074811B2 (en)	2006-07-11
IL151425A (en)	2009-08-03
UA73974C2 (en)	2005-10-17
AP2002002600A0 (en)	2002-09-30
SK286399B6 (sk)	2008-09-05
OA12229A (en)	2003-11-07
EP1265893A1 (en)	2002-12-18
ATE302202T1 (de)	2005-09-15
NZ520910A (en)	2004-06-25

Legal Events

Date	Code	Title	Description
2012-10-22	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
EP1265893B1 (en)	2005-08-17	Hydrochloride salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
NO317255B1 (no)	2004-09-27	Substituert tiazolidinderivat, fremgangsmate for fremstilling og anvendelse derav
NO320587B1 (no)	2005-12-27	Polymorf, anvendelse og fremstilling derav, samt farmasoytisk preparat.
US20070191435A1 (en)	2007-08-16	Hydrochloride salt of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
NO320609B1 (no)	2005-12-27	Hydroklorid-hydrat, anvendelse og fremstilling derav, samt farmasoytisk preparat.
NO320573B1 (no)	2005-12-27	Hydroklorid-hydrater, anvendelse og fremstilling derav, samt farmasoytisk preparat.
NO324595B1 (no)	2007-11-26	Tartratsalt av tiazolidindionderivat, fremgangsmate for fremstilling derav, anvendelse derav og farmasoytisk preparat omfattende saltet
US20040014790A1 (en)	2004-01-22	Tartrate salt of thiazolidinedione derivative
KR20030022356A (ko)	2003-03-15	티아졸리딘디온 유도체의 타르타르산염
NO324970B1 (no)	2008-01-14	Farmasoytisk preparat omfattende 5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]-benzyl]tiazolidin-2,4-dionkaliumsalt samt anvendelse av saltet
US20040102485A1 (en)	2004-05-27	Tartrate salt of thiazolidinedione derivative
MXPA03001083A (es)	2003-05-27	Farmaceutico novedoso .
HK1052502B (en)	2006-03-31	Hydrochloride salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
WO2003050111A1 (en)	2003-06-19	Toluenesulfonate salts of a thiazolidinedione derivative
WO2003050112A1 (en)	2003-06-19	Toluenesulfonate hydrates of a thiazolidinedione derivative
WO2003050114A1 (en)	2003-06-19	Sulfate salt of a thiazolidinedione derivative
HK1105818A (en)	2008-02-22	A thiazolidinedione derivative and its use as antidiabetic