NO327040B1 - Fremgangsmate ved fremstilling av 4-karboksy-5,8,11-tris-(karboksymetyl)-1-fenyl-2-oksa-5,8,11-triazatridekan-13-syre - Google Patents

Fremgangsmate ved fremstilling av 4-karboksy-5,8,11-tris-(karboksymetyl)-1-fenyl-2-oksa-5,8,11-triazatridekan-13-syre Download PDF

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Publication number
NO327040B1
NO327040B1 NO20006612A NO20006612A NO327040B1 NO 327040 B1 NO327040 B1 NO 327040B1 NO 20006612 A NO20006612 A NO 20006612A NO 20006612 A NO20006612 A NO 20006612A NO 327040 B1 NO327040 B1 NO 327040B1
Authority
NO
Norway
Prior art keywords
compound
solution
carried out
iii
reaction
Prior art date
Application number
NO20006612A
Other languages
English (en)
Norwegian (no)
Other versions
NO20006612D0 (no
NO20006612L (no
Inventor
Rodolfo Piva
Carlo Felice Viscardi
Marina Ausonio
Carlo Secchi
Carlo Distaso
Giuseppe Gerardo Elia
Alessandro Lesignoli
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Publication of NO20006612D0 publication Critical patent/NO20006612D0/no
Publication of NO20006612L publication Critical patent/NO20006612L/no
Publication of NO327040B1 publication Critical patent/NO327040B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20006612A 1998-07-10 2000-12-22 Fremgangsmate ved fremstilling av 4-karboksy-5,8,11-tris-(karboksymetyl)-1-fenyl-2-oksa-5,8,11-triazatridekan-13-syre NO327040B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT98MI001583A ITMI981583A1 (it) 1998-07-10 1998-07-10 Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico
PCT/EP1999/004478 WO2000002847A2 (en) 1998-07-10 1999-06-29 A process for the preparation of 4-carboxy- 5,8,11- tris(carboxymethyl)- 1-phenyl- 2-oxa- 5,8,11- triazatridecan- 13-oic acid

Publications (3)

Publication Number Publication Date
NO20006612D0 NO20006612D0 (no) 2000-12-22
NO20006612L NO20006612L (no) 2001-01-10
NO327040B1 true NO327040B1 (no) 2009-04-06

Family

ID=11380412

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20006612A NO327040B1 (no) 1998-07-10 2000-12-22 Fremgangsmate ved fremstilling av 4-karboksy-5,8,11-tris-(karboksymetyl)-1-fenyl-2-oksa-5,8,11-triazatridekan-13-syre
NO20084254A NO336375B1 (no) 1998-07-10 2008-10-10 Fremgangsmåte ved fremstilling av 2-klor-3-(fenylmetoksy)propionsyre-kaliumsalt (II)

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20084254A NO336375B1 (no) 1998-07-10 2008-10-10 Fremgangsmåte ved fremstilling av 2-klor-3-(fenylmetoksy)propionsyre-kaliumsalt (II)

Country Status (16)

Country Link
US (1) US6162947A (de)
EP (2) EP1588998B1 (de)
JP (1) JP4476486B2 (de)
KR (1) KR100651071B1 (de)
CN (2) CN1315776C (de)
AT (2) ATE535507T1 (de)
AU (1) AU770081B2 (de)
CA (3) CA2696806C (de)
DE (1) DE69925836T2 (de)
DK (1) DK1095009T3 (de)
ES (1) ES2243063T3 (de)
IL (1) IL140497A (de)
IT (1) ITMI981583A1 (de)
NO (2) NO327040B1 (de)
PT (1) PT1095009E (de)
WO (1) WO2000002847A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0325762D0 (en) * 2003-11-05 2003-12-10 Eastman Kodak Co Photographic bleach composition
EP1762563A1 (de) * 2005-09-13 2007-03-14 BRACCO IMAGING S.p.A. Verfahren zur Herstellung von Kontrastmitteln
TWI386384B (zh) * 2006-03-01 2013-02-21 高雄醫學大學 以環烷基三胺基五羧酸化合物作為配位子之具順磁性金屬錯合物
EP2338874A1 (de) * 2009-12-16 2011-06-29 Bracco Imaging S.p.A Verfahren zur Herstellung von chelatierten Verbindungen
CN102408348A (zh) * 2011-07-26 2012-04-11 天津市海文普宁科技发展有限公司 一种钆贝葡胺的制备新方法
CN102603550B (zh) * 2012-02-16 2014-11-26 佛山普正医药科技有限公司 一种中间体bopta的制备方法
EP2977369A1 (de) * 2014-07-24 2016-01-27 Bracco Imaging SPA Herstellung einer festen Form von Gadobenatdimeglumin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2820816A (en) * 1956-12-17 1958-01-21 Gen Aniline & Film Corp Preparation of alpha, beta-dichloropropionic acid esters
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
DE3814887C1 (de) * 1988-05-02 1989-09-21 Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De

Also Published As

Publication number Publication date
WO2000002847A2 (en) 2000-01-20
NO336375B1 (no) 2015-08-10
EP1095009B1 (de) 2005-06-15
ITMI981583A1 (it) 2000-01-10
KR20010071663A (ko) 2001-07-31
EP1588998B1 (de) 2011-11-30
JP2002520305A (ja) 2002-07-09
CN1210252C (zh) 2005-07-13
CN1307558A (zh) 2001-08-08
CN1315776C (zh) 2007-05-16
CA2619685A1 (en) 2000-01-20
AU770081B2 (en) 2004-02-12
DE69925836D1 (de) 2005-07-21
PT1095009E (pt) 2005-09-30
CA2336919C (en) 2009-12-22
WO2000002847A3 (en) 2000-04-27
ES2243063T3 (es) 2005-11-16
EP1095009A2 (de) 2001-05-02
NO20084254L (no) 2001-01-10
JP4476486B2 (ja) 2010-06-09
CA2696806C (en) 2012-03-13
IL140497A0 (en) 2002-02-10
ATE297890T1 (de) 2005-07-15
DK1095009T3 (da) 2005-10-03
CA2619685C (en) 2011-09-13
DE69925836T2 (de) 2005-10-27
KR100651071B1 (ko) 2006-11-28
NO20006612D0 (no) 2000-12-22
EP1588998A1 (de) 2005-10-26
CN1699325A (zh) 2005-11-23
NO20006612L (no) 2001-01-10
CA2336919A1 (en) 2000-01-20
US6162947A (en) 2000-12-19
ATE535507T1 (de) 2011-12-15
AU4779199A (en) 2000-02-01
IL140497A (en) 2004-06-01
CA2696806A1 (en) 2000-01-20

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