NO327697B1 - Dihydrobenzodiazepin-2-onderivater, farmasoytisk medikament omfattende slike, fremgangsmate for fremstilling av slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom - Google Patents

Dihydrobenzodiazepin-2-onderivater, farmasoytisk medikament omfattende slike, fremgangsmate for fremstilling av slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom Download PDF

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Publication number
NO327697B1
NO327697B1 NO20043237A NO20043237A NO327697B1 NO 327697 B1 NO327697 B1 NO 327697B1 NO 20043237 A NO20043237 A NO 20043237A NO 20043237 A NO20043237 A NO 20043237A NO 327697 B1 NO327697 B1 NO 327697B1
Authority
NO
Norway
Prior art keywords
phenyl
mmol
methyl
butyl ester
trifluoromethyl
Prior art date
Application number
NO20043237A
Other languages
English (en)
Norwegian (no)
Other versions
NO20043237L (no
Inventor
Thomas Johannes Woltering
Erwin Goetschi
Geo Adam
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20043237L publication Critical patent/NO20043237L/no
Publication of NO327697B1 publication Critical patent/NO327697B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20043237A 2002-02-06 2004-08-02 Dihydrobenzodiazepin-2-onderivater, farmasoytisk medikament omfattende slike, fremgangsmate for fremstilling av slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom NO327697B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02002012 2002-02-06
PCT/EP2003/000859 WO2003066623A1 (en) 2002-02-06 2003-01-28 Dihydrobenzodiazepin-2-one derivatives for the treatment of neurological disorders

Publications (2)

Publication Number Publication Date
NO20043237L NO20043237L (no) 2004-08-02
NO327697B1 true NO327697B1 (no) 2009-09-14

Family

ID=27675598

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043237A NO327697B1 (no) 2002-02-06 2004-08-02 Dihydrobenzodiazepin-2-onderivater, farmasoytisk medikament omfattende slike, fremgangsmate for fremstilling av slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom

Country Status (30)

Country Link
US (1) US6949542B2 (pl)
EP (1) EP1474416B1 (pl)
JP (1) JP4077411B2 (pl)
KR (1) KR20040081486A (pl)
CN (1) CN100497333C (pl)
AR (1) AR038481A1 (pl)
AT (1) ATE374196T1 (pl)
AU (1) AU2003205695B8 (pl)
BR (1) BR0307474A (pl)
CA (1) CA2474219C (pl)
DE (1) DE60316538T2 (pl)
DK (1) DK1474416T3 (pl)
ES (1) ES2294264T3 (pl)
GT (1) GT200300028A (pl)
HR (1) HRP20040678A2 (pl)
IL (1) IL163102A (pl)
MX (1) MXPA04007516A (pl)
MY (1) MY176608A (pl)
NO (1) NO327697B1 (pl)
NZ (1) NZ534122A (pl)
PA (1) PA8565901A1 (pl)
PE (1) PE20031011A1 (pl)
PL (1) PL372425A1 (pl)
PT (1) PT1474416E (pl)
RU (1) RU2315764C2 (pl)
SI (1) SI1474416T1 (pl)
TW (1) TWI326599B (pl)
UY (1) UY27654A1 (pl)
WO (1) WO2003066623A1 (pl)
ZA (1) ZA200406032B (pl)

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JP5204232B2 (ja) 2007-08-27 2013-06-05 エフ．ホフマン−ラ ロシュ アーゲー Ｆｘｒアゴニストとして使用されるベンゾイミダゾール誘導体
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Also Published As

Publication number Publication date
SI1474416T1 (sl) 2008-02-29
IL163102A (en) 2011-07-31
EP1474416B1 (en) 2007-09-26
ES2294264T3 (es) 2008-04-01
RU2315764C2 (ru) 2008-01-27
PA8565901A1 (es) 2003-09-05
US20030166639A1 (en) 2003-09-04
WO2003066623A1 (en) 2003-08-14
RU2004126945A (ru) 2005-06-27
TWI326599B (en) 2010-07-01
US6949542B2 (en) 2005-09-27
GT200300028A (es) 2004-06-11
HK1078858A1 (zh) 2006-03-24
MXPA04007516A (es) 2004-11-10
AR038481A1 (es) 2005-01-19
PL372425A1 (pl) 2005-07-25
CN1633430A (zh) 2005-06-29
ATE374196T1 (de) 2007-10-15
DE60316538D1 (de) 2007-11-08
EP1474416A1 (en) 2004-11-10
AU2003205695B8 (en) 2008-05-01
ZA200406032B (en) 2005-10-12
MY176608A (en) 2020-08-18
AU2003205695B2 (en) 2008-04-03
AU2003205695A1 (en) 2003-09-02
UY27654A1 (es) 2003-08-29
CA2474219C (en) 2010-04-13
JP2005522440A (ja) 2005-07-28
PT1474416E (pt) 2007-12-27
NO20043237L (no) 2004-08-02
KR20040081486A (ko) 2004-09-21
NZ534122A (en) 2006-12-22
HRP20040678A2 (en) 2005-10-31
CN100497333C (zh) 2009-06-10
DK1474416T3 (da) 2008-01-14
PE20031011A1 (es) 2003-11-29
DE60316538T2 (de) 2008-08-21
CA2474219A1 (en) 2003-08-14
JP4077411B2 (ja) 2008-04-16
BR0307474A (pt) 2004-11-09
TW200302730A (en) 2003-08-16

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