NO330342B1 - Ny fremgangsmate for fremstilling av imidazolylforbindelser - Google Patents

Ny fremgangsmate for fremstilling av imidazolylforbindelser Download PDF

Info

Publication number: NO330342B1
Authority: NO; Norway
Prior art keywords: hydrogen; alkyl; compound; butanol; methyl
Prior art date: 2002-11-18

Application number

NO20052950A

Other languages

English (en)

Norwegian (no)

Other versions

NO20052950D0 (no

NO20052950L (no

Inventor

Paulus Franciscus Cornelis Van Der Meij

Jan-Maarten Verbeek

Original Assignee

Solvay Pharm Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-18

Filing date

2005-06-16

Publication date

2011-03-28

2005-06-16 Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv

2005-06-16 Publication of NO20052950D0 publication Critical patent/NO20052950D0/no

2005-08-15 Publication of NO20052950L publication Critical patent/NO20052950L/no

2011-03-28 Publication of NO330342B1 publication Critical patent/NO330342B1/no

Links

238000000034 method Methods 0.000 title claims abstract 13
125000002883 imidazolyl group Chemical group 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 claims abstract 23
239000001257 hydrogen Substances 0.000 claims abstract 23
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 12
125000004178 (C1-C4) alkyl group Chemical group 0.000 claims abstract 10
125000004169 (C1-C6) alkyl group Chemical group 0.000 claims abstract 8
150000001875 compounds Chemical class 0.000 claims abstract 8
125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 6
239000002253 acid Substances 0.000 claims abstract 4
239000011203 carbon fibre reinforced carbon Substances 0.000 claims abstract 4
125000004183 alkoxy alkyl group Chemical group 0.000 claims abstract 3
229910052736 halogen Inorganic materials 0.000 claims abstract 3
-1 imidazolyl compound Chemical class 0.000 claims abstract 3
150000003839 salts Chemical class 0.000 claims abstract 3
125000003107 substituted aryl group Chemical group 0.000 claims abstract 3
125000003118 aryl group Chemical group 0.000 claims abstract 2
150000002367 halogens Chemical class 0.000 claims abstract 2
125000001072 heteroaryl group Chemical group 0.000 claims abstract 2
125000000623 heterocyclic group Chemical group 0.000 claims abstract 2
150000002431 hydrogen Chemical group 0.000 claims 5
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical group CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims 3
230000001476 alcoholic effect Effects 0.000 claims 3
125000000217 alkyl group Chemical group 0.000 claims 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
239000000203 mixture Substances 0.000 claims 3
239000002904 solvent Substances 0.000 claims 3
125000004429 atom Chemical group 0.000 claims 2
MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical compound ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 claims 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
230000007306 turnover Effects 0.000 claims 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 claims 1
125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 1
150000004945 aromatic hydrocarbons Chemical class 0.000 claims 1
125000005843 halogen group Chemical group 0.000 claims 1
125000001424 substituent group Chemical group 0.000 claims 1
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

NO20052950A 2002-11-18 2005-06-16 Ny fremgangsmate for fremstilling av imidazolylforbindelser NO330342B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02079838		2002-11-18
PCT/EP2003/050841 WO2004046116A1 (en)	2002-11-18	2003-11-17	Novel process for the preparation of imidazolyl compounds

Publications (3)

Publication Number	Publication Date
NO20052950D0 NO20052950D0 (no)	2005-06-16
NO20052950L NO20052950L (no)	2005-08-15
NO330342B1 true NO330342B1 (no)	2011-03-28

Family

ID=32319633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20052950A NO330342B1 (no)	2002-11-18	2005-06-16	Ny fremgangsmate for fremstilling av imidazolylforbindelser

Country Status (24)

Country	Link
EP (1)	EP1565445B1 (de)
JP (1)	JP4611026B2 (de)
KR (1)	KR20050075026A (de)
CN (1)	CN100349873C (de)
AR (1)	AR041955A1 (de)
AT (1)	ATE340783T1 (de)
AU (1)	AU2003296762B2 (de)
BR (1)	BR0316308A (de)
CA (1)	CA2504614C (de)
DE (1)	DE60308720T2 (de)
DK (1)	DK1565445T3 (de)
ES (1)	ES2273088T3 (de)
HR (1)	HRP20050376A2 (de)
IL (1)	IL168258A (de)
MX (1)	MXPA05005261A (de)
NO (1)	NO330342B1 (de)
PL (1)	PL376743A1 (de)
PT (1)	PT1565445E (de)
RU (1)	RU2314296C2 (de)
SA (1)	SA03240414B1 (de)
SI (1)	SI1565445T1 (de)
UA (1)	UA79655C2 (de)
WO (1)	WO2004046116A1 (de)
ZA (1)	ZA200503425B (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3885357T2 (de) *	1987-06-29	1994-03-24	Duphar Int Res	Anellierte Indolderivate.

2003
- 2003-11-13 AR ARP030104180A patent/AR041955A1/es unknown
- 2003-11-17 SI SI200330519T patent/SI1565445T1/sl unknown
- 2003-11-17 KR KR1020057008864A patent/KR20050075026A/ko not_active Abandoned
- 2003-11-17 MX MXPA05005261A patent/MXPA05005261A/es active IP Right Grant
- 2003-11-17 BR BR0316308-3A patent/BR0316308A/pt not_active Application Discontinuation
- 2003-11-17 UA UAA200505941A patent/UA79655C2/uk unknown
- 2003-11-17 CA CA2504614A patent/CA2504614C/en not_active Expired - Fee Related
- 2003-11-17 EP EP03811396A patent/EP1565445B1/de not_active Expired - Lifetime
- 2003-11-17 JP JP2004552730A patent/JP4611026B2/ja not_active Expired - Fee Related
- 2003-11-17 DE DE60308720T patent/DE60308720T2/de not_active Expired - Lifetime
- 2003-11-17 AT AT03811396T patent/ATE340783T1/de active
- 2003-11-17 WO PCT/EP2003/050841 patent/WO2004046116A1/en not_active Ceased
- 2003-11-17 CN CNB2003801035559A patent/CN100349873C/zh not_active Expired - Fee Related
- 2003-11-17 RU RU2005119155/04A patent/RU2314296C2/ru not_active IP Right Cessation
- 2003-11-17 ES ES03811396T patent/ES2273088T3/es not_active Expired - Lifetime
- 2003-11-17 AU AU2003296762A patent/AU2003296762B2/en not_active Ceased
- 2003-11-17 PT PT03811396T patent/PT1565445E/pt unknown
- 2003-11-17 PL PL376743A patent/PL376743A1/pl not_active Application Discontinuation
- 2003-11-17 HR HR20050376A patent/HRP20050376A2/xx not_active Application Discontinuation
- 2003-11-17 DK DK03811396T patent/DK1565445T3/da active
- 2003-12-03 SA SA03240414A patent/SA03240414B1/ar unknown
2005
- 2005-04-27 IL IL168258A patent/IL168258A/en not_active IP Right Cessation
- 2005-04-28 ZA ZA200503425A patent/ZA200503425B/xx unknown
- 2005-06-16 NO NO20052950A patent/NO330342B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE60308720T2 (de)	2007-01-11
RU2314296C2 (ru)	2008-01-10
ES2273088T3 (es)	2007-05-01
BR0316308A (pt)	2005-09-27
EP1565445A1 (de)	2005-08-24
CA2504614A1 (en)	2004-06-03
CA2504614C (en)	2010-09-28
DK1565445T3 (da)	2007-01-29
ATE340783T1 (de)	2006-10-15
MXPA05005261A (es)	2005-07-25
AU2003296762A1 (en)	2004-06-15
DE60308720D1 (de)	2006-11-09
JP2006512322A (ja)	2006-04-13
HK1081188A1 (zh)	2006-05-12
HRP20050376A2 (en)	2006-02-28
SA03240414B1 (ar)	2006-12-05
ZA200503425B (en)	2007-02-28
EP1565445B1 (de)	2006-09-27
AR041955A1 (es)	2005-06-01
NO20052950D0 (no)	2005-06-16
SI1565445T1 (sl)	2007-02-28
IL168258A (en)	2010-05-31
CN100349873C (zh)	2007-11-21
AU2003296762B2 (en)	2010-03-18
JP4611026B2 (ja)	2011-01-12
CN1714082A (zh)	2005-12-28
UA79655C2 (en)	2007-07-10
PL376743A1 (pl)	2006-01-09
NO20052950L (no)	2005-08-15
KR20050075026A (ko)	2005-07-19
RU2005119155A (ru)	2006-01-20
PT1565445E (pt)	2007-01-31
WO2004046116A1 (en)	2004-06-03

Legal Events

Date	Code	Title	Description
2012-06-25	MM1K	Lapsed by not paying the annual fees

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WO1993020066A1 (en)	1993-10-14	Imidazole, triazole and tetrazole derivatives
NO330342B1 (no)	2011-03-28	Ny fremgangsmate for fremstilling av imidazolylforbindelser
US7015333B2 (en)	2006-03-21	Process for preparation of imidazolyl compounds
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KR100368895B1 (ko)	2003-01-24	1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
KR100393744B1 (ko)	2003-08-02	1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
TW202610622A (zh)	2026-03-16	2-(3,5-二氯-1-甲基-吲唑-4-基)-1-[(1s,3r)-3-(羥甲基)-5-(1-羥基-1-甲基-乙基)-1-甲基-3,4-二氫-1h-異喹啉-2-基]乙酮一水合物之製造方法
TWI324595B (en)	2010-05-11	Novel process for the preparation of imidazolyl compounds
EP2462144B1 (de)	2017-09-20	Verfahren zur herstellung eines 2-alkinyl substituierten 5-amino-pyrazolo-[4, 3-e]-1,2,4-triazolo [1,5-c] pyrimidins
KR100377578B1 (ko)	2003-03-26	온단세트론 및 그의 염의 제조방법
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