NO331882B1 - Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader - Google Patents

Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader Download PDF

Info

Publication number: NO331882B1
Authority: NO; Norway
Prior art keywords: use according; inhibitor; injury; brain; interferon
Prior art date: 2001-05-25

Application number

NO20035160A

Other languages

English (en)

Norwegian (no)

Other versions

NO20035160D0 (no

NO20035160L (no

Inventor

Esther Shohami

Original Assignee

Ares Trading Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2003-11-20

Publication date

2012-04-23

2003-11-20 Application filed by Ares Trading Sa filed Critical Ares Trading Sa

2003-11-20 Publication of NO20035160D0 publication Critical patent/NO20035160D0/no

2003-11-20 Publication of NO20035160L publication Critical patent/NO20035160L/no

2012-04-23 Publication of NO331882B1 publication Critical patent/NO331882B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Mycology (AREA)
Microbiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)

NO20035160A 2001-05-25 2003-11-20 Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader NO331882B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01112067		2001-05-25
PCT/EP2002/005666 WO2002096456A1 (en)	2001-05-25	2002-05-23	Use of il-18 inhibitors for treating or preventing cns injuries

Publications (3)

Publication Number	Publication Date
NO20035160D0 NO20035160D0 (no)	2003-11-20
NO20035160L NO20035160L (no)	2003-11-20
NO331882B1 true NO331882B1 (no)	2012-04-23

Family

ID=8177454

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20035160A NO331882B1 (no)	2001-05-25	2003-11-20	Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader

Country Status (29)

Country	Link
US (1)	US7655616B2 (cs)
EP (1)	EP1390070B1 (cs)
JP (1)	JP4344142B2 (cs)
KR (1)	KR20040030625A (cs)
CN (1)	CN1305529C (cs)
AU (1)	AU2002314103B2 (cs)
BG (1)	BG66395B1 (cs)
BR (1)	BR0210007A (cs)
CA (1)	CA2445664C (cs)
CY (1)	CY1119190T1 (cs)
CZ (1)	CZ307321B6 (cs)
DK (1)	DK1390070T3 (cs)
EA (1)	EA006744B1 (cs)
EE (1)	EE05263B1 (cs)
ES (1)	ES2617084T3 (cs)
HR (1)	HRP20030842B1 (cs)
HU (1)	HU230294B1 (cs)
IL (2)	IL159014A0 (cs)
LT (1)	LT1390070T (cs)
ME (1)	ME00550B (cs)
MX (1)	MXPA03010743A (cs)
NO (1)	NO331882B1 (cs)
PL (1)	PL216228B1 (cs)
PT (1)	PT1390070T (cs)
RS (1)	RS56006B1 (cs)
SK (1)	SK288413B6 (cs)
UA (1)	UA80396C2 (cs)
WO (1)	WO2002096456A1 (cs)
ZA (1)	ZA200308172B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080076708A1 (en)	2003-05-13	2008-03-27	Valter Altarocca	Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
EP2177907B1 (en) *	2004-06-30	2014-01-01	Atsuo Sekiyama	Indicator agent for noninflammatory stress response and use therefor
ES2376534T3 (es) *	2005-06-03	2012-03-14	Merck Serono Sa	Uso de isoformas de il-18bp para el tratamiento y/o prevención de enfermedades inflamatorias neurológicas.
AU2006254103B2 (en)	2005-06-03	2012-09-06	Ares Trading S.A.	Production of recombinant IL-18 binding protein
AU2006256763B2 (en)	2005-06-10	2012-08-02	Ares Trading S.A.	Process for the purification of IL-18 binding protein
US8685400B2 (en)	2007-07-30	2014-04-01	University Of Miami	Modulating inflammasome activity and inflammation in the central nervous system
UA125204C2 (uk) *	2013-09-05	2022-02-02	Аб2 Біо Са	Застосування il-18-зв'язувального білка (il-18bp) при запальних захворюваннях
US10882905B2 (en) *	2015-03-05	2021-01-05	Ab2 Bio Sa	IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0873453A (ja) *	1994-09-02	1996-03-19	Otsuka Pharmaceut Co Ltd	サイトカイン阻害剤
IL121860A0 (en) *	1997-08-14	1998-02-22	Yeda Res & Dev	Interleukin-18 binding proteins their preparation and use
WO1999046248A1 (en) *	1998-03-09	1999-09-16	Vertex Pharmaceuticals Incorporated	1,2-diazepane derivatives as interleukin-1beta converting enzyme inhibitors
CA2276216A1 (en) *	1998-06-24	1999-12-24	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	An artificial peptide capable of neutralizing the biological activity of interleukin-18
CZ300792B6 (cs) *	2000-05-05	2009-08-12	Applied Research Systems Ars Holding N. V.	Farmaceutický prostredek
JP2003535892A (ja) *	2000-06-23	2003-12-02	イッサムリサーチディベロップメントカンパニーオブザヘブリューユニバーシティーオブエルサレム	２−アラキドニルグリセロール（２−ＡＧ）−腫瘍壊死因子−αの阻害剤および閉鎖性頭部損傷における脳の神経保護因子
WO2002032374A2 (en) *	2000-10-18	2002-04-25	Immunex Corporation	Methods for treating il-18 mediated disorders
US6671553B1 (en) *	2001-05-23	2003-12-30	Pacesetter, Inc.	Implantable cardiac lead having terminating connector strain relief and method of manufacture

2002
- 2002-05-23 HR HRP20030842AA patent/HRP20030842B1/hr not_active IP Right Cessation
- 2002-05-23 BR BR0210007-0A patent/BR0210007A/pt not_active Application Discontinuation
- 2002-05-23 US US10/478,614 patent/US7655616B2/en not_active Expired - Lifetime
- 2002-05-23 EA EA200301299A patent/EA006744B1/ru not_active IP Right Cessation
- 2002-05-23 UA UA20031212328A patent/UA80396C2/uk unknown
- 2002-05-23 SK SK1603-2003A patent/SK288413B6/sk not_active IP Right Cessation
- 2002-05-23 ES ES02740641.2T patent/ES2617084T3/es not_active Expired - Lifetime
- 2002-05-23 CZ CZ2003-3268A patent/CZ307321B6/cs not_active IP Right Cessation
- 2002-05-23 IL IL15901402A patent/IL159014A0/xx unknown
- 2002-05-23 LT LTEP02740641.2T patent/LT1390070T/lt unknown
- 2002-05-23 WO PCT/EP2002/005666 patent/WO2002096456A1/en not_active Ceased
- 2002-05-23 CN CNB028147510A patent/CN1305529C/zh not_active Expired - Lifetime
- 2002-05-23 RS YU89403A patent/RS56006B1/sr unknown
- 2002-05-23 JP JP2002592965A patent/JP4344142B2/ja not_active Expired - Lifetime
- 2002-05-23 EE EEP200300582A patent/EE05263B1/xx unknown
- 2002-05-23 PL PL367545A patent/PL216228B1/pl unknown
- 2002-05-23 MX MXPA03010743A patent/MXPA03010743A/es active IP Right Grant
- 2002-05-23 DK DK02740641.2T patent/DK1390070T3/en active
- 2002-05-23 AU AU2002314103A patent/AU2002314103B2/en not_active Expired
- 2002-05-23 CA CA2445664A patent/CA2445664C/en not_active Expired - Lifetime
- 2002-05-23 ME MEP-2008-618A patent/ME00550B/me unknown
- 2002-05-23 KR KR10-2003-7015310A patent/KR20040030625A/ko not_active Ceased
- 2002-05-23 EP EP02740641.2A patent/EP1390070B1/en not_active Expired - Lifetime
- 2002-05-23 PT PT2740641T patent/PT1390070T/pt unknown
- 2002-05-23 HU HU0304067A patent/HU230294B1/hu unknown
2003
- 2003-10-21 ZA ZA200308172A patent/ZA200308172B/xx unknown
- 2003-11-20 NO NO20035160A patent/NO331882B1/no not_active IP Right Cessation
- 2003-11-23 IL IL159014A patent/IL159014A/en active IP Right Grant
- 2003-12-15 BG BG108451A patent/BG66395B1/bg unknown
2017
- 2017-05-08 CY CY20171100494T patent/CY1119190T1/el unknown

Also Published As

Publication number	Publication date
BG66395B1 (bg)	2013-12-31
EP1390070B1 (en)	2017-02-08
YU89403A (sh)	2006-05-25
IL159014A0 (en)	2004-05-12
HU230294B1 (hu)	2015-12-28
IL159014A (en)	2012-05-31
RS56006B1 (sr)	2017-09-29
ES2617084T3 (es)	2017-06-15
ME00550B (me)	2011-10-10
CN1535160A (zh)	2004-10-06
HUP0304067A3 (en)	2006-01-30
AU2002314103B8 (en)	2002-12-09
PT1390070T (pt)	2017-03-01
US7655616B2 (en)	2010-02-02
CY1119190T1 (el)	2018-02-14
CN1305529C (zh)	2007-03-21
JP2004534777A (ja)	2004-11-18
EE200300582A (et)	2004-02-16
EP1390070A1 (en)	2004-02-25
HRP20030842B1 (hr)	2017-06-02
CZ20033268A3 (en)	2004-07-14
MXPA03010743A (es)	2004-03-02
NO20035160D0 (no)	2003-11-20
AU2002314103B2 (en)	2007-07-12
SK16032003A3 (sk)	2004-05-04
PL216228B1 (pl)	2014-03-31
JP4344142B2 (ja)	2009-10-14
LT1390070T (lt)	2017-03-10
HRP20030842A2 (en)	2005-08-31
BR0210007A (pt)	2004-08-10
BG108451A (en)	2005-02-28
PL367545A1 (en)	2005-02-21
WO2002096456A1 (en)	2002-12-05
EE05263B1 (et)	2010-02-15
HK1069762A1 (en)	2005-06-03
CA2445664C (en)	2012-03-06
CZ307321B6 (cs)	2018-06-06
EA200301299A1 (ru)	2004-04-29
NO20035160L (no)	2003-11-20
UA80396C2 (en)	2007-09-25
KR20040030625A (ko)	2004-04-09
CA2445664A1 (en)	2002-12-05
ZA200308172B (en)	2004-10-21
EA006744B1 (ru)	2006-04-28
SK288413B6 (sk)	2016-10-03
HUP0304067A2 (hu)	2004-03-29
US20040191247A1 (en)	2004-09-30
DK1390070T3 (en)	2017-04-24

Legal Events

Date	Code	Title	Description
2022-06-13	MK1K	Patent expired

Publication	Publication Date	Title
EP1425028B1 (en)	2009-12-16	Use of il-18 inhibitors for the treatement or prevention of sepsis
HRP20040758A2 (en)	2005-02-28	Use of il-18 inhibitors for the treatment and/or prevention of peripheral vascular diseases
KR20070087256A (ko)	2007-08-27	Ｉｌ-18 저해물질의 용도
NO329821B1 (no)	2010-12-27	Anvendelse av IL-18 inhibitorer, ekspresjonsvektorer som koder for IL-18 inhibitorer og celler genetisk modifisert til a fremstille inhibitorer av IL-18 for fremstilling av medikamenter til behandling og/eller forebygging av aterosklerose, samt anvendelse av IL-18 som diagnostisk markor for progresjon av aterosklerose
US20070173439A1 (en)	2007-07-26	Interleukin-18 binding proteins, their preparation and use
NO331882B1 (no)	2012-04-23	Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader
AU2002314103A1 (en)	2003-05-08	Use of IL-18 inhibitors for treating or preventing CNS injuries
NO335688B1 (no)	2015-01-19	Anvendelse av IL-18-inhibitorer i hypersensitivitetslidelser.
AU2002331376A1 (en)	2003-06-19	Use of IL-18 inhibitors in hypersensitivity disorders
AU2002309887B2 (en)	2008-11-27	Use of IL-18 inhibitors for the treatment or prevention of sepsis
NO339540B1 (no)	2016-12-27	Anvendelse av IL-18BP isoformer til behandling og/eller forhindring av neurologiske inflammatoriske sykdommer
HK1066723B (en)	2010-03-12	Use of il-18 inhibitors for the treatment or prevention of sepsis
AU2002309887A1 (en)	2003-05-01	Use of IL-18 inhibitors for the treatment or prevention of sepsis