NO331882B1 - Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader - Google Patents

Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader Download PDF

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Publication number
NO331882B1
NO331882B1 NO20035160A NO20035160A NO331882B1 NO 331882 B1 NO331882 B1 NO 331882B1 NO 20035160 A NO20035160 A NO 20035160A NO 20035160 A NO20035160 A NO 20035160A NO 331882 B1 NO331882 B1 NO 331882B1
Authority
NO
Norway
Prior art keywords
use according
inhibitor
injury
brain
interferon
Prior art date
Application number
NO20035160A
Other languages
English (en)
Norwegian (no)
Other versions
NO20035160L (no
NO20035160D0 (no
Inventor
Esther Shohami
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of NO20035160L publication Critical patent/NO20035160L/no
Publication of NO20035160D0 publication Critical patent/NO20035160D0/no
Publication of NO331882B1 publication Critical patent/NO331882B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20035160A 2001-05-25 2003-11-20 Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader NO331882B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01112067 2001-05-25
PCT/EP2002/005666 WO2002096456A1 (en) 2001-05-25 2002-05-23 Use of il-18 inhibitors for treating or preventing cns injuries

Publications (3)

Publication Number Publication Date
NO20035160L NO20035160L (no) 2003-11-20
NO20035160D0 NO20035160D0 (no) 2003-11-20
NO331882B1 true NO331882B1 (no) 2012-04-23

Family

ID=8177454

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20035160A NO331882B1 (no) 2001-05-25 2003-11-20 Anvendelse av IL-18 inhibitorer til a behandle eller forhindre CNS-skader

Country Status (29)

Country Link
US (1) US7655616B2 (sr)
EP (1) EP1390070B1 (sr)
JP (1) JP4344142B2 (sr)
KR (1) KR20040030625A (sr)
CN (1) CN1305529C (sr)
AU (1) AU2002314103B2 (sr)
BG (1) BG66395B1 (sr)
BR (1) BR0210007A (sr)
CA (1) CA2445664C (sr)
CY (1) CY1119190T1 (sr)
CZ (1) CZ307321B6 (sr)
DK (1) DK1390070T3 (sr)
EA (1) EA006744B1 (sr)
EE (1) EE05263B1 (sr)
ES (1) ES2617084T3 (sr)
HR (1) HRP20030842B1 (sr)
HU (1) HU230294B1 (sr)
IL (2) IL159014A0 (sr)
LT (1) LT1390070T (sr)
ME (1) ME00550B (sr)
MX (1) MXPA03010743A (sr)
NO (1) NO331882B1 (sr)
PL (1) PL216228B1 (sr)
PT (1) PT1390070T (sr)
RS (1) RS56006B1 (sr)
SK (1) SK288413B6 (sr)
UA (1) UA80396C2 (sr)
WO (1) WO2002096456A1 (sr)
ZA (1) ZA200308172B (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1622939T3 (da) 2003-05-13 2012-04-10 Merck Serono Sa Aktive varianter af det IL-18-bindende protein og medicinske anvendelser deraf
EP1780542A4 (en) * 2004-06-30 2008-05-14 Atsuo Sekiyama AGENT INDICATING A NON-INFLAMMATORY RESPONSE TO A STRESS AND USE THEREOF
ES2385639T3 (es) 2005-06-03 2012-07-27 Ares Trading S.A. Producción de una proteína de unión a IL-18 recombinante
ATE530227T1 (de) * 2005-06-03 2011-11-15 Merck Serono Sa Verwendung von il-18bp-isoformen zur behandlung und/oder vorbeugung neurologischer entzündungskrankheiten
AU2006256763B2 (en) 2005-06-10 2012-08-02 Ares Trading S.A. Process for the purification of IL-18 binding protein
US8685400B2 (en) 2007-07-30 2014-04-01 University Of Miami Modulating inflammasome activity and inflammation in the central nervous system
PT3041864T (pt) * 2013-09-05 2021-10-26 Ab2 Bio Sa Proteína de ligação a il-18 (il-18bp) em doenças inflamatórias
UA128752C2 (uk) 2015-03-05 2024-10-16 Аб2 Біо Са Фармацевтична композиція для лікування асоційованого з il-18 захворювання або порушення

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0873453A (ja) * 1994-09-02 1996-03-19 Otsuka Pharmaceut Co Ltd サイトカイン阻害剤
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
WO1999046248A1 (en) * 1998-03-09 1999-09-16 Vertex Pharmaceuticals Incorporated 1,2-diazepane derivatives as interleukin-1beta converting enzyme inhibitors
CA2276216A1 (en) * 1998-06-24 1999-12-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo An artificial peptide capable of neutralizing the biological activity of interleukin-18
CZ300792B6 (cs) * 2000-05-05 2009-08-12 Applied Research Systems Ars Holding N. V. Farmaceutický prostredek
EP1292288B1 (en) * 2000-06-23 2004-09-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem 2-arachidonylglycerol (2-ag) - an inhibitor of tumor necrosis factor -alfa and neuroprotector of brain in closed head injury
AU2002224417A1 (en) * 2000-10-18 2002-04-29 Immunex Corporation Methods for treating il-18 mediated disorders
US6671553B1 (en) * 2001-05-23 2003-12-30 Pacesetter, Inc. Implantable cardiac lead having terminating connector strain relief and method of manufacture

Also Published As

Publication number Publication date
IL159014A0 (en) 2004-05-12
DK1390070T3 (en) 2017-04-24
CZ20033268A3 (en) 2004-07-14
MXPA03010743A (es) 2004-03-02
BG108451A (en) 2005-02-28
CN1535160A (zh) 2004-10-06
HUP0304067A3 (en) 2006-01-30
ME00550B (me) 2011-10-10
CA2445664A1 (en) 2002-12-05
HU230294B1 (hu) 2015-12-28
ZA200308172B (en) 2004-10-21
NO20035160L (no) 2003-11-20
PL216228B1 (pl) 2014-03-31
US20040191247A1 (en) 2004-09-30
AU2002314103B8 (en) 2002-12-09
PT1390070T (pt) 2017-03-01
BR0210007A (pt) 2004-08-10
LT1390070T (lt) 2017-03-10
AU2002314103B2 (en) 2007-07-12
KR20040030625A (ko) 2004-04-09
JP4344142B2 (ja) 2009-10-14
UA80396C2 (en) 2007-09-25
EE200300582A (et) 2004-02-16
CY1119190T1 (el) 2018-02-14
ES2617084T3 (es) 2017-06-15
EA200301299A1 (ru) 2004-04-29
CN1305529C (zh) 2007-03-21
HRP20030842B1 (hr) 2017-06-02
US7655616B2 (en) 2010-02-02
WO2002096456A1 (en) 2002-12-05
EP1390070A1 (en) 2004-02-25
SK288413B6 (sk) 2016-10-03
YU89403A (sh) 2006-05-25
HK1069762A1 (en) 2005-06-03
PL367545A1 (en) 2005-02-21
RS56006B1 (sr) 2017-09-29
JP2004534777A (ja) 2004-11-18
EA006744B1 (ru) 2006-04-28
HUP0304067A2 (hu) 2004-03-29
BG66395B1 (bg) 2013-12-31
NO20035160D0 (no) 2003-11-20
IL159014A (en) 2012-05-31
SK16032003A3 (sk) 2004-05-04
EE05263B1 (et) 2010-02-15
EP1390070B1 (en) 2017-02-08
CA2445664C (en) 2012-03-06
HRP20030842A2 (en) 2005-08-31
CZ307321B6 (cs) 2018-06-06

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