NO772167L - Sulfonamid/potensiatoroppl¦sninger - Google Patents

Sulfonamid/potensiatoroppl¦sninger

Info

Publication number: NO772167L
Authority: NO; Norway
Prior art keywords: approx; weight; solutions; glycerol formal; potentiator
Prior art date: 1976-06-21

Application number

NO772167A

Other languages

English (en)

Norwegian (no)

Inventor

Klaus Stoll

Helmut Franz

Original Assignee

Saarstickstoff Fatol Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-21

Filing date

1977-06-20

Publication date

1977-12-22

1977-06-20 Application filed by Saarstickstoff Fatol Gmbh filed Critical Saarstickstoff Fatol Gmbh

1977-12-22 Publication of NO772167L publication Critical patent/NO772167L/no

Links

229940124530 sulfonamide Drugs 0.000 title claims description 17
FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 31
229940074076 glycerol formal Drugs 0.000 claims description 31
239000013543 active substance Substances 0.000 claims description 26
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
150000003456 sulfonamides Chemical class 0.000 claims description 15
235000011389 fruit/vegetable juice Nutrition 0.000 claims description 9
239000000203 mixture Substances 0.000 claims description 9
229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 8
239000001267 polyvinylpyrrolidone Substances 0.000 claims description 8
235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 8
230000007935 neutral effect Effects 0.000 claims description 7
239000000126 substance Substances 0.000 claims description 7
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 6
GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims description 6
229920001400 block copolymer Polymers 0.000 claims description 6
235000003599 food sweetener Nutrition 0.000 claims description 6
239000003765 sweetening agent Substances 0.000 claims description 6
239000002253 acid Substances 0.000 claims description 5
-1 amine salt Chemical class 0.000 claims description 5
238000004519 manufacturing process Methods 0.000 claims description 5
239000003513 alkali Substances 0.000 claims description 4
239000008365 aqueous carrier Substances 0.000 claims description 4
235000020354 squash Nutrition 0.000 claims description 4
238000000034 method Methods 0.000 claims 3
230000001225 therapeutic effect Effects 0.000 claims 2
239000000243 solution Substances 0.000 description 44
IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 12
238000002360 preparation method Methods 0.000 description 11
JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 11
229960001082 trimethoprim Drugs 0.000 description 11
229960005404 sulfamethoxazole Drugs 0.000 description 10
235000019441 ethanol Nutrition 0.000 description 9
235000008504 concentrate Nutrition 0.000 description 8
239000012141 concentrate Substances 0.000 description 8
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 8
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
239000002904 solvent Substances 0.000 description 6
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 5
235000002639 sodium chloride Nutrition 0.000 description 5
239000000725 suspension Substances 0.000 description 5
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 4
238000001802 infusion Methods 0.000 description 4
239000004310 lactic acid Substances 0.000 description 4
235000014655 lactic acid Nutrition 0.000 description 4
YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
235000020357 syrup Nutrition 0.000 description 4
239000006188 syrup Substances 0.000 description 4
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
150000001875 compounds Chemical class 0.000 description 3
LDBTVAXGKYIFHO-UHFFFAOYSA-N diaveridine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=CN=C(N)N=C1N LDBTVAXGKYIFHO-UHFFFAOYSA-N 0.000 description 3
239000003978 infusion fluid Substances 0.000 description 3
238000001556 precipitation Methods 0.000 description 3
CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 2
KEEYRKYKLYARHO-UHFFFAOYSA-N 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine Chemical compound C1=C(OC)C(OC)=CC(C)=C1CC1=CN=C(N)N=C1N KEEYRKYKLYARHO-UHFFFAOYSA-N 0.000 description 2
UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 2
239000002202 Polyethylene glycol Substances 0.000 description 2
239000003242 anti bacterial agent Substances 0.000 description 2
235000019658 bitter taste Nutrition 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 2
229950000246 diaveridine Drugs 0.000 description 2
238000004090 dissolution Methods 0.000 description 2
239000003814 drug Substances 0.000 description 2
239000003921 oil Substances 0.000 description 2
239000003960 organic solvent Substances 0.000 description 2
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
238000007911 parenteral administration Methods 0.000 description 2
229920001223 polyethylene glycol Polymers 0.000 description 2
229960004889 salicylic acid Drugs 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
239000001509 sodium citrate Substances 0.000 description 2
229960001462 sodium cyclamate Drugs 0.000 description 2
239000001540 sodium lactate Substances 0.000 description 2
229940005581 sodium lactate Drugs 0.000 description 2
235000011088 sodium lactate Nutrition 0.000 description 2
159000000000 sodium salts Chemical class 0.000 description 2
FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
VCKSNYNNVSOWEE-UHFFFAOYSA-N 1,3-dioxan-5-ol Chemical compound OC1COCOC1 VCKSNYNNVSOWEE-UHFFFAOYSA-N 0.000 description 1
BOHGAOWOIJMTPZ-UHFFFAOYSA-N 1,3-dioxolan-4-ylmethanol Chemical compound OCC1COCO1 BOHGAOWOIJMTPZ-UHFFFAOYSA-N 0.000 description 1
RJQQOKKINHMXIM-UHFFFAOYSA-N 2-hydroxypropanoate;tris(2-hydroxyethyl)azanium Chemical compound CC(O)C(O)=O.OCCN(CCO)CCO RJQQOKKINHMXIM-UHFFFAOYSA-N 0.000 description 1
MIDXCONKKJTLDX-UHFFFAOYSA-N 3,5-dimethylcyclopentane-1,2-dione Chemical compound CC1CC(C)C(=O)C1=O MIDXCONKKJTLDX-UHFFFAOYSA-N 0.000 description 1
NHZLNPMOSADWGC-UHFFFAOYSA-N 4-amino-N-(2-quinoxalinyl)benzenesulfonamide Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=CN=C(C=CC=C2)C2=N1 NHZLNPMOSADWGC-UHFFFAOYSA-N 0.000 description 1
QSCDJPXGCZNSNJ-UHFFFAOYSA-N 4-amino-n-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound O1C(C)=C(C)N=C1NS(=O)(=O)C1=CC=C(N)C=C1.COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 QSCDJPXGCZNSNJ-UHFFFAOYSA-N 0.000 description 1
IEAAAQXTROJCRL-UHFFFAOYSA-N 5-[(2,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound COC1=CC(OC)=C(OC)C=C1CC1=CN=C(N)N=C1N IEAAAQXTROJCRL-UHFFFAOYSA-N 0.000 description 1
208000035143 Bacterial infection Diseases 0.000 description 1
JXBWCGNCBYXUJG-UHFFFAOYSA-N CC1=C(C)OC(NS)=N1 Chemical compound CC1=C(C)OC(NS)=N1 JXBWCGNCBYXUJG-UHFFFAOYSA-N 0.000 description 1
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
UYUXSRADSPPKRZ-SKNVOMKLSA-N D-glucurono-6,3-lactone Chemical compound O=C[C@H](O)[C@H]1OC(=O)[C@@H](O)[C@H]1O UYUXSRADSPPKRZ-SKNVOMKLSA-N 0.000 description 1
IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
206010022998 Irritability Diseases 0.000 description 1
VJHFHHLMXJVUSR-UHFFFAOYSA-N N-(5-methyl-1,2-oxazol-3-yl)thiohydroxylamine Chemical compound CC1=CC(NS)=NO1 VJHFHHLMXJVUSR-UHFFFAOYSA-N 0.000 description 1
235000012550 Pimpinella anisum Nutrition 0.000 description 1
240000004760 Pimpinella anisum Species 0.000 description 1
RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
ABBQHOQBGMUPJH-UHFFFAOYSA-M Sodium salicylate Chemical compound [Na+].OC1=CC=CC=C1C([O-])=O ABBQHOQBGMUPJH-UHFFFAOYSA-M 0.000 description 1
PJSFRIWCGOHTNF-UHFFFAOYSA-N Sulphormetoxin Chemical compound COC1=NC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1OC PJSFRIWCGOHTNF-UHFFFAOYSA-N 0.000 description 1
239000001089 [(2R)-oxolan-2-yl]methanol Substances 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000002411 adverse Effects 0.000 description 1
IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 1
150000001447 alkali salts Chemical class 0.000 description 1
150000003973 alkyl amines Chemical class 0.000 description 1
150000001412 amines Chemical class 0.000 description 1
239000003708 ampul Substances 0.000 description 1
239000010617 anise oil Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
239000002585 base Substances 0.000 description 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
235000013736 caramel Nutrition 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
229940001468 citrate Drugs 0.000 description 1
229960004106 citric acid Drugs 0.000 description 1
229940003898 combination of sulfonamides Drugs 0.000 description 1
239000008121 dextrose Substances 0.000 description 1
HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 description 1
MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
238000009826 distribution Methods 0.000 description 1
229940079593 drug Drugs 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000007717 exclusion Effects 0.000 description 1
229940097043 glucuronic acid Drugs 0.000 description 1
150000002334 glycols Chemical class 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
229960000448 lactic acid Drugs 0.000 description 1
210000000056 organ Anatomy 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
239000002504 physiological saline solution Substances 0.000 description 1
229920001993 poloxamer 188 Polymers 0.000 description 1
229960000611 pyrimethamine Drugs 0.000 description 1
WKSAUQYGYAYLPV-UHFFFAOYSA-N pyrimethamine Chemical compound CCC1=NC(N)=NC(N)=C1C1=CC=C(Cl)C=C1 WKSAUQYGYAYLPV-UHFFFAOYSA-N 0.000 description 1
229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 description 1
YAAWASYJIRZXSZ-UHFFFAOYSA-N pyrimidine-2,4-diamine Chemical class NC1=CC=NC(N)=N1 YAAWASYJIRZXSZ-UHFFFAOYSA-N 0.000 description 1
150000003230 pyrimidines Chemical class 0.000 description 1
230000000241 respiratory effect Effects 0.000 description 1
229940081974 saccharin Drugs 0.000 description 1
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
235000019204 saccharin Nutrition 0.000 description 1
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
229940085605 saccharin sodium Drugs 0.000 description 1
229960001860 salicylate Drugs 0.000 description 1
YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
229960004025 sodium salicylate Drugs 0.000 description 1
239000011877 solvent mixture Substances 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000004659 sterilization and disinfection Methods 0.000 description 1
238000003860 storage Methods 0.000 description 1
SEEPANYCNGTZFQ-UHFFFAOYSA-N sulfadiazine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=NC=CC=N1 SEEPANYCNGTZFQ-UHFFFAOYSA-N 0.000 description 1
229960004306 sulfadiazine Drugs 0.000 description 1
ZZORFUFYDOWNEF-UHFFFAOYSA-N sulfadimethoxine Chemical compound COC1=NC(OC)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ZZORFUFYDOWNEF-UHFFFAOYSA-N 0.000 description 1
229960000973 sulfadimethoxine Drugs 0.000 description 1
229960004673 sulfadoxine Drugs 0.000 description 1
229940006995 sulfamethoxazole and trimethoprim Drugs 0.000 description 1
229960001363 sulfamoxole Drugs 0.000 description 1
CYFLXLSBHQBMFT-UHFFFAOYSA-N sulfamoxole Chemical compound O1C(C)=C(C)N=C1NS(=O)(=O)C1=CC=C(N)C=C1 CYFLXLSBHQBMFT-UHFFFAOYSA-N 0.000 description 1
229940007000 sulfamoxole and trimethoprim Drugs 0.000 description 1
235000019640 taste Nutrition 0.000 description 1
BSYVTEYKTMYBMK-UHFFFAOYSA-N tetrahydrofurfuryl alcohol Chemical compound OCC1CCCO1 BSYVTEYKTMYBMK-UHFFFAOYSA-N 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
230000002110 toxicologic effect Effects 0.000 description 1
231100000027 toxicology Toxicity 0.000 description 1
229940062461 triethanolamine lactate Drugs 0.000 description 1
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
235000012141 vanillin Nutrition 0.000 description 1
238000004383 yellowing Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

NO772167A 1976-06-21 1977-06-20 Sulfonamid/potensiatoroppl¦sninger NO772167L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2627706A DE2627706C2 (de)	1976-06-21	1976-06-21	Verfahren zur Herstellung von neutralen beständigen, mit Wasser zu klaren Lösungen verdünnbaren Sulfonamid-Potentiatorlösungen

Publications (1)

Publication Number	Publication Date
NO772167L true NO772167L (no)	1977-12-22

Family

ID=5981032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO772167A NO772167L (no)	1976-06-21	1977-06-20	Sulfonamid/potensiatoroppl¦sninger

Country Status (11)

Country	Link
JP (1)	JPS533513A (fr)
AU (1)	AU514197B2 (fr)
BE (1)	BE855687A (fr)
CA (1)	CA1073353A (fr)
DE (1)	DE2627706C2 (fr)
DK (1)	DK143997C (fr)
FR (1)	FR2355503A1 (fr)
GB (1)	GB1540177A (fr)
NL (1)	NL7706841A (fr)
NO (1)	NO772167L (fr)
SE (1)	SE7706807L (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2631780C3 (de) *	1976-07-15	1981-11-19	Basf Ag, 6700 Ludwigshafen	Sulfonamid-Trimethoprim-Lösungen
EP0009559B1 (fr) *	1978-08-01	1982-08-25	Ciba-Geigy Ag	Formulation pharmaceutique liquide, stable, sa préparation et son application
IE49933B1 (en) *	1979-07-05	1986-01-08	Pfizer	Sulfonamide solutions
CN114129510A (zh) *	2021-12-03	2022-03-04	聊城大学	一种复方磺胺注射剂及制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1044231B (it) *	1972-03-16	1980-03-20	Hoffmann La Roche	Combinazione di sostanze attive utile per combattere infezioni da batteri gram positivi e gran negativi

1976
- 1976-06-21 DE DE2627706A patent/DE2627706C2/de not_active Expired
1977
- 1977-06-13 SE SE7706807A patent/SE7706807L/xx unknown
- 1977-06-14 BE BE178447A patent/BE855687A/fr not_active IP Right Cessation
- 1977-06-17 CA CA280,759A patent/CA1073353A/fr not_active Expired
- 1977-06-17 AU AU26179/77A patent/AU514197B2/en not_active Expired
- 1977-06-20 NO NO772167A patent/NO772167L/no unknown
- 1977-06-20 JP JP7377477A patent/JPS533513A/ja active Pending
- 1977-06-21 FR FR7718921A patent/FR2355503A1/fr active Granted
- 1977-06-21 DK DK273677A patent/DK143997C/da active
- 1977-06-21 NL NL7706841A patent/NL7706841A/xx not_active Application Discontinuation
- 1977-06-21 GB GB25987/77A patent/GB1540177A/en not_active Expired

Also Published As

Publication number	Publication date
NL7706841A (nl)	1977-12-23
AU2617977A (en)	1978-12-21
AU514197B2 (en)	1981-01-29
DK273677A (da)	1977-12-22
JPS533513A (en)	1978-01-13
BE855687A (fr)	1977-10-03
CA1073353A (fr)	1980-03-11
FR2355503A1 (fr)	1978-01-20
GB1540177A (en)	1979-02-07
SE7706807L (sv)	1977-12-22
DE2627706A1 (de)	1977-12-22
DK143997C (da)	1982-04-19
DK143997B (da)	1981-11-16
DE2627706C2 (de)	1982-11-18
FR2355503B1 (fr)	1980-06-27

Publication	Publication Date	Title
TW537895B (en)	2003-06-21	Aqueous solution preparation containing gatifloxacin
EP1575585B1 (fr)	2010-04-28	Composition pharmaceutique liquide contenant un derive de pyridone
JPS6191116A (ja)	1986-05-09	安定化された注射用ピロキシカム液剤
US3985876A (en)	1976-10-12	Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine
KR950010158B1 (ko)	1995-09-11	사용하도록 준비된 토라세미드의 주사용액 및 이들의 제조방법
AU599034B2 (en)	1990-07-12	Furosemide salts
WO2004112761A2 (fr)	2004-12-29	Compositions pharmaceutiques stables de 5,10-methylene-tetrahydrofolate
RU2363462C2 (ru)	2009-08-10	Фармацевтическая композиция, содержащая 5-метил-2-(2′-хлор-6′-фторанилин)фенилуксусную кислоту
KR840000702B1 (ko)	1984-05-21	빈카민 사카리네이트의 제조방법
NO140578B (no)	1979-06-25	Fremgangsmaate til fremstilling av en klar injiserbar opploesning
CA1073353A (fr)	1980-03-11	Solutions d'un potentiateur et d'un sulfonamide
DK159376B (da)	1990-10-08	Fremgangsmaade til fremstilling af et stabilt, fast, vandoploeseligt praeparat til rekonstituering med vand eller en vandig baerer som en stabil oploesning af 4'-(9-acridinylamino)methan-sulfon-m-anisid
US6127425A (en)	2000-10-03	Oral liquid medicine solution
US4327084A (en)	1982-04-27	Aqueous solution for intravenous administration
US2888381A (en)	1959-05-26	Solutions of citrus bioflavonoids
JP2002502808A (ja)	2002-01-29	医薬組成物
US2438880A (en)	1948-03-30	Riboflavin solution
JP2001131070A (ja)	2001-05-15	リボフラビン配合液剤組成物
KR100825572B1 (ko)	2008-04-25	칼슘, 마그네슘 및 비타민을 포함하는 액제 조성물 및 그의제조방법
HU208071B (en)	1993-08-30	Process for producing pentamidine solution
EP0021847B1 (fr)	1983-07-20	Compositions injectables de sulfonamide à effet prolongé
Britton et al.	1931	The oral administration of cortico-adrenal extract
US2128851A (en)	1938-08-30	Theophylline-piperazine preparations
US4742082A (en)	1988-05-03	Solution of luprostiol and 1,2,-propanediol and methods of preparation and use
BR112020004453A2 (pt)	2020-09-15	composição para suplementação de cálcio