NO773362L - PROCEDURE FOR PREPARING 9-CHLORINE PREDNISOLON DERIVATIVES - Google Patents

PROCEDURE FOR PREPARING 9-CHLORINE PREDNISOLON DERIVATIVES

Info

Publication number: NO773362L
Authority: NO; Norway
Prior art keywords: prednisolon; chlorine; derivatives; preparing; procedure
Prior art date: 1976-10-04

Application number

NO773362A

Other languages

Norwegian (no)

Other versions

NO148597C (en

NO148597B (en

Inventor

Klaus Annen

Henry Laurent

Helmut Hofmeister

Rudolf Wiechert

Hans Wendt

Joachim Friedrich Kapp

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-10-04

Filing date

1977-10-03

Publication date

1978-04-05

1976-10-04 Priority claimed from DE2645105A external-priority patent/DE2645105C2/en

1977-09-21 Priority claimed from DE19772742982 external-priority patent/DE2742982C2/en

1977-10-03 Application filed by Schering Ag filed Critical Schering Ag

1978-04-05 Publication of NO773362L publication Critical patent/NO773362L/en

1983-08-01 Publication of NO148597B publication Critical patent/NO148597B/en

1983-11-09 Publication of NO148597C publication Critical patent/NO148597C/en

Links

229910052801 chlorine Inorganic materials 0.000 title 1
239000000460 chlorine Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO773362A 1976-10-04 1977-10-03 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 9-CHLOROUS PREPARATION INSULATES NO148597C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2645105A DE2645105C2 (en)	1976-10-04	1976-10-04	Derivatives of 9-chlorprednisolone, process for their preparation and pharmaceutical preparation containing them
DE19772742982 DE2742982C2 (en)	1977-09-21	1977-09-21	9-chlorprednisolone derivatives, process for their production and pharmaceutical preparation containing them

Publications (3)

Publication Number	Publication Date
NO773362L true NO773362L (en)	1978-04-05
NO148597B NO148597B (en)	1983-08-01
NO148597C NO148597C (en)	1983-11-09

Family

ID=25770978

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO773362A NO148597C (en)	1976-10-04	1977-10-03	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 9-CHLOROUS PREPARATION INSULATES

Country Status (21)

Country	Link
JP (1)	JPS5359654A (en)
AT (1)	AT358202B (en)
CH (4)	CH630098A5 (en)
DK (1)	DK438277A (en)
ES (1)	ES462887A1 (en)
FI (1)	FI58645C (en)
FR (1)	FR2366313A1 (en)
GB (1)	GB1594852A (en)
GR (1)	GR73041B (en)
HU (1)	HU179593B (en)
IE (1)	IE45877B1 (en)
IL (1)	IL53030A (en)
IT (1)	IT1113623B (en)
LU (1)	LU78223A1 (en)
NL (1)	NL7710869A (en)
NO (1)	NO148597C (en)
NZ (1)	NZ185295A (en)
PL (1)	PL110392B1 (en)
PT (1)	PT67109B (en)
SE (1)	SE431655B (en)
SU (2)	SU743581A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2853785A1 (en) *	1978-12-11	1980-06-19	Schering Ag	NEW PREDNISON DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS AND THE USE THEREOF
JPH0374245A (en) *	1989-08-12	1991-03-28	Mk Seiko Co Ltd	car wash machine
US8513247B2 (en)	2010-03-26	2013-08-20	Galderma Laboratories, L.P.	Methods and compositions for safe and effective treatment of erythema
PH12014500783A1 (en)	2011-10-19	2014-05-12	Galderma Sa	Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (en) *	2016-12-16	2017-05-10	广州仁恒医药科技股份有限公司	Method for preparing difluprednate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH429716A (en) *	1961-06-24	1967-02-15	Vismara Francesco Spa	Process for the preparation of 17a-acyloxy-21-hydroxy steroids
DE2055221A1 (en) *	1970-11-10	1972-05-18	Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien)	17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

1977
- 1977-09-29 NZ NZ185295A patent/NZ185295A/en unknown
- 1977-09-30 IL IL53030A patent/IL53030A/en unknown
- 1977-09-30 PL PL1977201161A patent/PL110392B1/en unknown
- 1977-09-30 CH CH1199177A patent/CH630098A5/en not_active IP Right Cessation
- 1977-10-03 AT AT703577A patent/AT358202B/en not_active IP Right Cessation
- 1977-10-03 GR GR54473A patent/GR73041B/el unknown
- 1977-10-03 LU LU78223A patent/LU78223A1/xx unknown
- 1977-10-03 GB GB40924/77A patent/GB1594852A/en not_active Expired
- 1977-10-03 IE IE2011/77A patent/IE45877B1/en unknown
- 1977-10-03 SE SE7711039A patent/SE431655B/en not_active IP Right Cessation
- 1977-10-03 HU HU77SCHE624A patent/HU179593B/en unknown
- 1977-10-03 NO NO773362A patent/NO148597C/en unknown
- 1977-10-03 PT PT67109A patent/PT67109B/en unknown
- 1977-10-03 IT IT28201/77A patent/IT1113623B/en active
- 1977-10-04 JP JP11940077A patent/JPS5359654A/en active Granted
- 1977-10-04 ES ES462887A patent/ES462887A1/en not_active Expired
- 1977-10-04 DK DK438277A patent/DK438277A/en not_active Application Discontinuation
- 1977-10-04 SU SU772526300A patent/SU743581A3/en active
- 1977-10-04 NL NL7710869A patent/NL7710869A/en not_active Application Discontinuation
- 1977-10-04 FR FR7729740A patent/FR2366313A1/en active Granted
- 1977-10-04 FI FI772922A patent/FI58645C/en not_active IP Right Cessation
1978
- 1978-10-13 SU SU782672298A patent/SU751327A3/en active
1981
- 1981-09-08 CH CH579281A patent/CH632772A5/en not_active IP Right Cessation
- 1981-09-08 CH CH579381A patent/CH632278A5/en not_active IP Right Cessation
- 1981-09-08 CH CH579481A patent/CH631997A5/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IE45877L (en)	1978-04-04
ES462887A1 (en)	1978-12-16
FI58645B (en)	1980-11-28
IL53030A0 (en)	1977-11-30
FR2366313A1 (en)	1978-04-28
ATA703577A (en)	1980-01-15
SU743581A3 (en)	1980-06-25
PT67109B (en)	1979-03-14
NO148597C (en)	1983-11-09
PT67109A (en)	1977-11-01
CH632772A5 (en)	1982-10-29
GR73041B (en)	1984-01-26
JPS6129960B2 (en)	1986-07-10
IL53030A (en)	1982-11-30
HU179593B (en)	1982-11-29
NL7710869A (en)	1978-04-06
CH630098A5 (en)	1982-05-28
AT358202B (en)	1980-08-25
SE431655B (en)	1984-02-20
SU751327A3 (en)	1980-07-23
PL201161A1 (en)	1979-01-29
LU78223A1 (en)	1978-02-01
FI772922A7 (en)	1978-04-05
IE45877B1 (en)	1982-12-15
PL110392B1 (en)	1980-07-31
CH632278A5 (en)	1982-09-30
IT1113623B (en)	1986-01-20
NO148597B (en)	1983-08-01
FR2366313B1 (en)	1980-02-01
NZ185295A (en)	1980-04-28
FI58645C (en)	1981-03-10
JPS5359654A (en)	1978-05-29
SE7711039L (en)	1978-04-05
GB1594852A (en)	1981-08-05
CH631997A5 (en)	1982-09-15
DK438277A (en)	1978-04-05

Publication	Publication Date	Title
NO782768L (en)	1979-02-23	PROCEDURE FOR PREPARING ALKENDER DERIVATIVES
RO76589A (en)	1981-04-30	PROCEDURE FOR PREPARING HETEROCYCLIC ALCHILAMINS
SE7808485L (en)	1979-02-10	PROCEDURE FOR PREPARING OLIGOIMIDES
SE440501B (en)	1985-08-05	PROCEDURE FOR PREPARING SUBSTITUTED PHENYLAMIDOXIMES
NO773548L (en)	1978-04-19	PROCEDURE FOR PREPARING SPIRO-HYDANTO INTERVENTIVES
SE432595B (en)	1984-04-09	ANALOGY PROCEDURE FOR PIPERIDYL-INDOLD DERIVATIVE PREPARATION
SE7808059L (en)	1979-01-23	PROCEDURE FOR PREPARING 1,2,4-TRIAZIN-5-ON DERIVATIVES
SE7807240L (en)	1978-12-28	PROCEDURE FOR PREPARING PARA-BENZOCINONE
SE433745B (en)	1984-06-12	PROCEDURE FOR PREPARING TETRAHYDROISOKINOLIN DERIVATIVES
SE433212B (en)	1984-05-14	PROCEDURE FOR PREPARING 4-HYDROXY-APORPHINE DERIVATIVES
SE438856B (en)	1985-05-13	ANALOGY PROCEDURE FOR PREPARING 1-ACYLOXIMETHYL-3-FLUORURACYL DERIVATIVES
NO152220C (en)	1985-08-21	PROCEDURE FOR PREPARING SESQUITER PENDING DERIVATIVES
SE431871B (en)	1984-03-05	PROCEDURE FOR PREPARING 2-BROMO-6-FLUORO-N-2-IMIDAZOLIDINYLIDEENBENAMINE
NO791604L (en)	1979-11-16	PROCEDURE FOR PREPARING DI-O-N-ALKYL-GLYCEROL DERIVATIVES
SE433219B (en)	1984-05-14	PROCEDURE FOR PREPARING 3-HALOGENE METHYLPHEALOSPOR COMPOUNDS
SE7613768L (en)	1977-06-14	PROCEDURE FOR PREPARING PENICILLINES
SE443140B (en)	1986-02-17	PROCEDURE FOR PREPARING CARBOSTYRIC DERIVATIVES
SE439631B (en)	1985-06-24	PROCEDURE FOR PREPARING 3,4-DIHYDROCARBOSTYRYL DERIVATIVES
NO773073L (en)	1978-03-21	PROCEDURE FOR PREPARING 2-PIPERAZINYL-CHINAZOLINE DERIVATIVES
SE431336B (en)	1984-01-30	ANALOGY PROCEDURE FOR PREPARING SUBSTITUTED 8-AZAPURIN DERIVATIVES
SE421125B (en)	1981-11-30	PROCEDURE FOR PREPARING 5-M-TOLYLOXIURACIL
NO773362L (en)	1978-04-05	PROCEDURE FOR PREPARING 9-CHLORINE PREDNISOLON DERIVATIVES
SE418287B (en)	1981-05-18	PROCEDURE FOR PREPARING GUAJAKOL-P-ISOBUTYL HYDRATROPATH
SE420093B (en)	1981-09-14	PROCEDURE FOR PREPARING 5-PHENYL-2-FURAMIDOXIMER
NO791994L (en)	1979-12-18	PROCEDURE FOR PREPARING 2-ISOPROPYLAMINO-PYRIMIDINE