NO773362L - Fremgangsmaate ved fremstilling av 9-klorprednisolonderivater - Google Patents

Fremgangsmaate ved fremstilling av 9-klorprednisolonderivater

Info

Publication number: NO773362L
Authority: NO; Norway
Prior art keywords: prednisolon; chlorine; derivatives; preparing; procedure
Prior art date: 1976-10-04

Application number

NO773362A

Other languages

English (en)

Other versions

NO148597C (no

NO148597B (no

Inventor

Klaus Annen

Henry Laurent

Helmut Hofmeister

Rudolf Wiechert

Hans Wendt

Joachim Friedrich Kapp

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-10-04

Filing date

1977-10-03

Publication date

1978-04-05

1976-10-04 Priority claimed from DE2645105A external-priority patent/DE2645105C2/de

1977-09-21 Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de

1977-10-03 Application filed by Schering Ag filed Critical Schering Ag

1978-04-05 Publication of NO773362L publication Critical patent/NO773362L/no

1983-08-01 Publication of NO148597B publication Critical patent/NO148597B/no

1983-11-09 Publication of NO148597C publication Critical patent/NO148597C/no

Links

229910052801 chlorine Inorganic materials 0.000 title 1
239000000460 chlorine Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO773362A 1976-10-04 1977-10-03 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 9-klorprednisolonderivater NO148597C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2645105A DE2645105C2 (de)	1976-10-04	1976-10-04	Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de)	1977-09-21	1977-09-21	9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (3)

Publication Number	Publication Date
NO773362L true NO773362L (no)	1978-04-05
NO148597B NO148597B (no)	1983-08-01
NO148597C NO148597C (no)	1983-11-09

Family

ID=25770978

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO773362A NO148597C (no)	1976-10-04	1977-10-03	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 9-klorprednisolonderivater

Country Status (21)

Country	Link
JP (1)	JPS5359654A (no)
AT (1)	AT358202B (no)
CH (4)	CH630098A5 (no)
DK (1)	DK438277A (no)
ES (1)	ES462887A1 (no)
FI (1)	FI58645C (no)
FR (1)	FR2366313A1 (no)
GB (1)	GB1594852A (no)
GR (1)	GR73041B (no)
HU (1)	HU179593B (no)
IE (1)	IE45877B1 (no)
IL (1)	IL53030A (no)
IT (1)	IT1113623B (no)
LU (1)	LU78223A1 (no)
NL (1)	NL7710869A (no)
NO (1)	NO148597C (no)
NZ (1)	NZ185295A (no)
PL (1)	PL110392B1 (no)
PT (1)	PT67109B (no)
SE (1)	SE431655B (no)
SU (2)	SU743581A3 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2853785A1 (de) *	1978-12-11	1980-06-19	Schering Ag	Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) *	1989-08-12	1991-03-28	Mk Seiko Co Ltd	洗車機
CN106038476B (zh)	2010-03-26	2020-04-17	盖尔德马研究及发展公司	安全和有效治疗红斑的改进的方法和组合物
EP2768502A2 (en)	2011-10-19	2014-08-27	Galderma S.A.	Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (zh) *	2016-12-16	2017-05-10	广州仁恒医药科技股份有限公司	一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH429716A (de) *	1961-06-24	1967-02-15	Vismara Francesco Spa	Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
DE2055221A1 (en) *	1970-11-10	1972-05-18	Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien)	17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

1977
- 1977-09-29 NZ NZ185295A patent/NZ185295A/xx unknown
- 1977-09-30 CH CH1199177A patent/CH630098A5/de not_active IP Right Cessation
- 1977-09-30 IL IL53030A patent/IL53030A/xx unknown
- 1977-09-30 PL PL1977201161A patent/PL110392B1/pl unknown
- 1977-10-03 GB GB40924/77A patent/GB1594852A/en not_active Expired
- 1977-10-03 IT IT28201/77A patent/IT1113623B/it active
- 1977-10-03 NO NO773362A patent/NO148597C/no unknown
- 1977-10-03 LU LU78223A patent/LU78223A1/xx unknown
- 1977-10-03 HU HU77SCHE624A patent/HU179593B/hu unknown
- 1977-10-03 AT AT703577A patent/AT358202B/de not_active IP Right Cessation
- 1977-10-03 SE SE7711039A patent/SE431655B/xx not_active IP Right Cessation
- 1977-10-03 IE IE2011/77A patent/IE45877B1/en unknown
- 1977-10-03 GR GR54473A patent/GR73041B/el unknown
- 1977-10-03 PT PT67109A patent/PT67109B/pt unknown
- 1977-10-04 JP JP11940077A patent/JPS5359654A/ja active Granted
- 1977-10-04 NL NL7710869A patent/NL7710869A/xx not_active Application Discontinuation
- 1977-10-04 DK DK438277A patent/DK438277A/da not_active Application Discontinuation
- 1977-10-04 FR FR7729740A patent/FR2366313A1/fr active Granted
- 1977-10-04 SU SU772526300A patent/SU743581A3/ru active
- 1977-10-04 FI FI772922A patent/FI58645C/fi not_active IP Right Cessation
- 1977-10-04 ES ES462887A patent/ES462887A1/es not_active Expired
1978
- 1978-10-13 SU SU782672298A patent/SU751327A3/ru active
1981
- 1981-09-08 CH CH579481A patent/CH631997A5/de not_active IP Right Cessation
- 1981-09-08 CH CH579281A patent/CH632772A5/de not_active IP Right Cessation
- 1981-09-08 CH CH579381A patent/CH632278A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
NL7710869A (nl)	1978-04-06
PL201161A1 (pl)	1979-01-29
ATA703577A (de)	1980-01-15
PT67109B (de)	1979-03-14
NO148597C (no)	1983-11-09
FR2366313A1 (fr)	1978-04-28
IT1113623B (it)	1986-01-20
GB1594852A (en)	1981-08-05
CH632772A5 (en)	1982-10-29
SE7711039L (sv)	1978-04-05
JPS6129960B2 (no)	1986-07-10
IL53030A (en)	1982-11-30
CH631997A5 (en)	1982-09-15
IE45877B1 (en)	1982-12-15
SU743581A3 (ru)	1980-06-25
HU179593B (en)	1982-11-29
FR2366313B1 (no)	1980-02-01
FI772922A7 (fi)	1978-04-05
SU751327A3 (ru)	1980-07-23
LU78223A1 (no)	1978-02-01
JPS5359654A (en)	1978-05-29
IL53030A0 (en)	1977-11-30
CH630098A5 (en)	1982-05-28
NZ185295A (en)	1980-04-28
GR73041B (no)	1984-01-26
AT358202B (de)	1980-08-25
IE45877L (en)	1978-04-04
FI58645B (fi)	1980-11-28
FI58645C (fi)	1981-03-10
SE431655B (sv)	1984-02-20
CH632278A5 (en)	1982-09-30
PT67109A (de)	1977-11-01
PL110392B1 (en)	1980-07-31
ES462887A1 (es)	1978-12-16
DK438277A (da)	1978-04-05
NO148597B (no)	1983-08-01

Publication	Publication Date	Title
NO782768L (no)	1979-02-23	Fremgangsmaate for fremstilling av alkenderivater
RO76589A (ro)	1981-04-30	Procedeu pentru prepararea alchilaminelor heterociclice
SE7808485L (sv)	1979-02-10	Forfarande for framstellning av oligoimider
SE440501B (sv)	1985-08-05	Forfarande for framstellning av substituerade fenylamidoximer
NO773548L (no)	1978-04-19	Fremgangsmaate for fremstilling av spiro-hydantoinderivater
SE432595B (sv)	1984-04-09	Analogiforfarande for framstellning av piperidyl-indolderivat
SE7808059L (sv)	1979-01-23	Forfarande for framstellning av 1,2,4-triazin-5-on-derivat
SE7807240L (sv)	1978-12-28	Forfarande for framstellning av para-bensokinon
SE433745B (sv)	1984-06-12	Forfarande for framstellning av tetrahydroisokinolinderivat
SE433212B (sv)	1984-05-14	Forfarande for framstellning av 4-hydroxi-aporfin-derivat
SE438856B (sv)	1985-05-13	Analogiforfarande for framstellning av 1-acyloximetyl-3-fluoruracilderivat
NO152220C (no)	1985-08-21	Fremgangsmaate for fremstilling av sesquiterpenderivat
SE431871B (sv)	1984-03-05	Forfarande for framstellning av 2-brom-6-fluor-n-2-imidazolidinylidenbensamin
NO791604L (no)	1979-11-16	Fremangsmaate for fremstilling av di-o-n-alkyl-glycerolderivater
SE433219B (sv)	1984-05-14	Forfarande for framstellning av 3-halogenmetylcefalosporinforeningar
SE7613768L (sv)	1977-06-14	Forfarande for framstellning av penicillinestrar
SE443140B (sv)	1986-02-17	Forfarande for framstellning av karbostyrilderivat
SE439631B (sv)	1985-06-24	Forfarande for framstellning av 3,4-dihydrokarbostyrilderivat
NO773073L (no)	1978-03-21	Fremgangsmaate for fremstilling av 2-piperazinyl-kinazolinderivater
SE431336B (sv)	1984-01-30	Analogiforfarande for framstellning av substituerade 8-azapurinderivat
SE421125B (sv)	1981-11-30	Forfarande for framstellning av 5-m-tolyloxiuracil
NO773362L (no)	1978-04-05	Fremgangsmaate ved fremstilling av 9-klorprednisolonderivater
SE418287B (sv)	1981-05-18	Forfarande for framstellning av guajakol-p-isobutyl-hydratropat
SE420093B (sv)	1981-09-14	Forfarande for framstellning av 5-fenyl-2-furamidoximer
NO791994L (no)	1979-12-18	Fremgangsmaate for fremstilling av 2-isopropylamino-pyrimidin