NO773487L - Fremgangsmaate til fremstilling av magnesiumsalter av p-klorfenoksyiso-smoersyre - Google Patents
Fremgangsmaate til fremstilling av magnesiumsalter av p-klorfenoksyiso-smoersyreInfo
- Publication number
- NO773487L NO773487L NO773487A NO773487A NO773487L NO 773487 L NO773487 L NO 773487L NO 773487 A NO773487 A NO 773487A NO 773487 A NO773487 A NO 773487A NO 773487 L NO773487 L NO 773487L
- Authority
- NO
- Norway
- Prior art keywords
- magnesium
- solution
- acid
- salt
- stirred
- Prior art date
Links
- 159000000003 magnesium salts Chemical class 0.000 title claims description 31
- 238000000034 method Methods 0.000 title claims description 18
- 239000002253 acid Substances 0.000 title description 7
- 238000002360 preparation method Methods 0.000 title description 2
- TXCGAZHTZHNUAI-UHFFFAOYSA-N clofibric acid Chemical compound OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 TXCGAZHTZHNUAI-UHFFFAOYSA-N 0.000 claims description 44
- 239000000243 solution Substances 0.000 claims description 44
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims description 28
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 21
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims description 12
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 12
- 235000011114 ammonium hydroxide Nutrition 0.000 claims description 12
- 239000011777 magnesium Substances 0.000 claims description 12
- 229910052749 magnesium Inorganic materials 0.000 claims description 12
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 10
- -1 ammonium ions Chemical class 0.000 claims description 7
- 238000006243 chemical reaction Methods 0.000 claims description 7
- 229910021529 ammonia Inorganic materials 0.000 claims description 6
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 5
- 229910001425 magnesium ion Inorganic materials 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 230000007306 turnover Effects 0.000 claims description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- 239000013078 crystal Substances 0.000 description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 150000002681 magnesium compounds Chemical class 0.000 description 12
- 239000000395 magnesium oxide Substances 0.000 description 11
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 11
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 11
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 238000002844 melting Methods 0.000 description 9
- 230000008018 melting Effects 0.000 description 9
- 235000019270 ammonium chloride Nutrition 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 238000003756 stirring Methods 0.000 description 8
- 238000002425 crystallisation Methods 0.000 description 7
- 230000008025 crystallization Effects 0.000 description 7
- 238000010992 reflux Methods 0.000 description 7
- 238000009835 boiling Methods 0.000 description 6
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 6
- 239000000347 magnesium hydroxide Substances 0.000 description 6
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 6
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 5
- 239000001095 magnesium carbonate Substances 0.000 description 5
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 5
- 239000011541 reaction mixture Substances 0.000 description 5
- 150000003863 ammonium salts Chemical class 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 150000004685 tetrahydrates Chemical class 0.000 description 4
- 230000005764 inhibitory process Effects 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012266 salt solution Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- KJTLQQUUPVSXIM-ZCFIWIBFSA-N (R)-mevalonic acid Chemical compound OCC[C@](O)(C)CC(O)=O KJTLQQUUPVSXIM-ZCFIWIBFSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 102000000452 Acetyl-CoA carboxylase Human genes 0.000 description 1
- 108010016219 Acetyl-CoA carboxylase Proteins 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- KJTLQQUUPVSXIM-UHFFFAOYSA-N DL-mevalonic acid Natural products OCCC(O)(C)CC(O)=O KJTLQQUUPVSXIM-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 229940100228 acetyl coenzyme a Drugs 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004136 fatty acid synthesis Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000000055 hyoplipidemic effect Effects 0.000 description 1
- UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 description 1
- 239000011654 magnesium acetate Substances 0.000 description 1
- 235000011285 magnesium acetate Nutrition 0.000 description 1
- 229940069446 magnesium acetate Drugs 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- JWSMTBMIGYJJJM-UHFFFAOYSA-N magnesium;azane Chemical compound N.[Mg+2] JWSMTBMIGYJJJM-UHFFFAOYSA-N 0.000 description 1
- 238000006241 metabolic reaction Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000009790 rate-determining step (RDS) Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT775176A AT346313B (de) | 1976-10-18 | 1976-10-18 | Verfahren zur herstellung des magnesiumsalzes der p-chlorphenoxyisobuttersaeure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO773487L true NO773487L (no) | 1978-04-19 |
Family
ID=3599120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO773487A NO773487L (no) | 1976-10-18 | 1977-10-12 | Fremgangsmaate til fremstilling av magnesiumsalter av p-klorfenoksyiso-smoersyre |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4126636A (de) |
| AT (1) | AT346313B (de) |
| AU (1) | AU511212B2 (de) |
| BE (1) | BE859861A (de) |
| CA (1) | CA1085872A (de) |
| CH (1) | CH628013A5 (de) |
| DE (1) | DE2745717A1 (de) |
| DK (1) | DK462777A (de) |
| ES (1) | ES463262A1 (de) |
| FI (1) | FI773043A7 (de) |
| FR (1) | FR2367726A1 (de) |
| GB (1) | GB1590973A (de) |
| GR (1) | GR61999B (de) |
| NL (1) | NL7711367A (de) |
| NO (1) | NO773487L (de) |
| PT (1) | PT67138B (de) |
| SE (1) | SE421068B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN160141B (de) * | 1983-05-09 | 1987-06-27 | Council Scient Ind Res |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH423748A (fr) * | 1965-05-11 | 1966-11-15 | Vifor Sa | Procédé de préparation du bis-a-(para-chlorophénoxy)-isobutyrate d'aluminium |
| AT265243B (de) * | 1965-05-11 | 1968-10-10 | Solac S A Lab | Verfahren zur Herstellung von neuen Salzen der p-Chlorphenoxyisobuttersäure |
| GB1422679A (en) * | 1972-11-16 | 1976-01-28 | Funai Pharmaceutical Ind Ltd | Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same |
| AT346310B (de) * | 1974-05-10 | 1978-11-10 | Broschek G Chem Prod Gebro | Verfahren zur herstellung von magnesiumsalzen von phenoxyalkansaeuren |
| BE834197A (fr) * | 1975-10-03 | 1976-02-02 | Procede de preparation de sels de magnesium d'acides phenoxyalcanoiques |
-
1976
- 1976-10-18 AT AT775176A patent/AT346313B/de not_active IP Right Cessation
-
1977
- 1977-09-29 GR GR54454A patent/GR61999B/el unknown
- 1977-10-04 SE SE7711081A patent/SE421068B/xx unknown
- 1977-10-07 CH CH1226777A patent/CH628013A5/de not_active IP Right Cessation
- 1977-10-11 PT PT67138A patent/PT67138B/de unknown
- 1977-10-11 DE DE19772745717 patent/DE2745717A1/de not_active Withdrawn
- 1977-10-12 NO NO773487A patent/NO773487L/no unknown
- 1977-10-13 GB GB42701/77A patent/GB1590973A/en not_active Expired
- 1977-10-13 US US05/841,835 patent/US4126636A/en not_active Expired - Lifetime
- 1977-10-14 CA CA288,759A patent/CA1085872A/en not_active Expired
- 1977-10-14 FI FI773043A patent/FI773043A7/fi not_active Application Discontinuation
- 1977-10-15 ES ES463262A patent/ES463262A1/es not_active Expired
- 1977-10-17 DK DK462777A patent/DK462777A/da not_active Application Discontinuation
- 1977-10-17 NL NL7711367A patent/NL7711367A/xx not_active Application Discontinuation
- 1977-10-18 AU AU29825/77A patent/AU511212B2/en not_active Expired
- 1977-10-18 FR FR7731321A patent/FR2367726A1/fr active Pending
- 1977-10-18 BE BE181854A patent/BE859861A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE7711081L (sv) | 1978-04-19 |
| AT346313B (de) | 1978-11-10 |
| CH628013A5 (en) | 1982-02-15 |
| US4126636A (en) | 1978-11-21 |
| ES463262A1 (es) | 1978-07-16 |
| NL7711367A (nl) | 1978-04-20 |
| FR2367726A1 (fr) | 1978-05-12 |
| GB1590973A (en) | 1981-06-10 |
| PT67138A (de) | 1977-11-01 |
| AU2982577A (en) | 1979-04-26 |
| AU511212B2 (en) | 1980-07-31 |
| ATA775176A (de) | 1978-03-15 |
| GR61999B (en) | 1979-02-14 |
| PT67138B (de) | 1979-03-19 |
| CA1085872A (en) | 1980-09-16 |
| BE859861A (fr) | 1978-02-15 |
| DK462777A (da) | 1978-04-19 |
| DE2745717A1 (de) | 1978-04-20 |
| SE421068B (sv) | 1981-11-23 |
| FI773043A7 (fi) | 1978-04-19 |
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