NO781792L - Fremgangsmaate for fremstilling av n-(3`-fenyltiopropyl)-3,3-difenylpropylamin - Google Patents
Fremgangsmaate for fremstilling av n-(3`-fenyltiopropyl)-3,3-difenylpropylaminInfo
- Publication number
- NO781792L NO781792L NO78781792A NO781792A NO781792L NO 781792 L NO781792 L NO 781792L NO 78781792 A NO78781792 A NO 78781792A NO 781792 A NO781792 A NO 781792A NO 781792 L NO781792 L NO 781792L
- Authority
- NO
- Norway
- Prior art keywords
- diphenylpropylamino
- phenylthiopropyl
- preparation
- solution
- diphenylpropylamine
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 9
- 238000002360 preparation method Methods 0.000 title description 4
- RMVRSNDYEFQCLF-UHFFFAOYSA-N thiophenol Chemical class SC1=CC=CC=C1 RMVRSNDYEFQCLF-UHFFFAOYSA-N 0.000 claims description 11
- -1 alkali metal salt Chemical class 0.000 claims description 7
- WRHVTZPMHLZXDV-UHFFFAOYSA-N 3-(3,3-diphenylpropylamino)propan-1-ol Chemical compound C=1C=CC=CC=1C(CCNCCCO)C1=CC=CC=C1 WRHVTZPMHLZXDV-UHFFFAOYSA-N 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- NUWWGCMQIKROIJ-UHFFFAOYSA-N 3,3-diphenyl-n-(3-phenylsulfanylpropyl)propan-1-amine Chemical compound C=1C=CC=CC=1SCCCNCCC(C=1C=CC=CC=1)C1=CC=CC=C1 NUWWGCMQIKROIJ-UHFFFAOYSA-N 0.000 claims description 2
- 229910052783 alkali metal Inorganic materials 0.000 claims description 2
- 229950000188 halopropane Drugs 0.000 claims description 2
- 159000000000 sodium salts Chemical class 0.000 claims 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 description 3
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 239000012044 organic layer Substances 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- NYVQQTOGYLBBDQ-UHFFFAOYSA-N 1-thiophen-2-ylpropan-2-amine Chemical compound CC(N)CC1=CC=CS1 NYVQQTOGYLBBDQ-UHFFFAOYSA-N 0.000 description 1
- SFYVRUBKBDKDBR-UHFFFAOYSA-N 3,3-diphenylpropyl(3-phenylsulfanylpropyl)azanium;chloride Chemical compound Cl.C=1C=CC=CC=1SCCCNCCC(C=1C=CC=CC=1)C1=CC=CC=C1 SFYVRUBKBDKDBR-UHFFFAOYSA-N 0.000 description 1
- KISZTEOELCMZPY-UHFFFAOYSA-N 3,3-diphenylpropylamine Chemical compound C=1C=CC=CC=1C(CCN)C1=CC=CC=C1 KISZTEOELCMZPY-UHFFFAOYSA-N 0.000 description 1
- LAMUXTNQCICZQX-UHFFFAOYSA-N 3-chloropropan-1-ol Chemical compound OCCCCl LAMUXTNQCICZQX-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- PHSPJQZRQAJPPF-UHFFFAOYSA-N N-alpha-Methylhistamine Chemical compound CNCCC1=CN=CN1 PHSPJQZRQAJPPF-UHFFFAOYSA-N 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000009518 sodium iodide Nutrition 0.000 description 1
- LKYIPGJOXSVWPX-UHFFFAOYSA-M sodium;thiophene-2-carboxylate Chemical compound [Na+].[O-]C(=O)C1=CC=CS1 LKYIPGJOXSVWPX-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT03455/77A IT1080452B (it) | 1977-05-24 | 1977-05-24 | Procedimento per la preparazione di n 3 feniltiopropil 3.3 difenilpropilamina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO781792L true NO781792L (no) | 1978-11-27 |
Family
ID=11107686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO78781792A NO781792L (no) | 1977-05-24 | 1978-05-23 | Fremgangsmaate for fremstilling av n-(3`-fenyltiopropyl)-3,3-difenylpropylamin |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS53149959A (da) |
| DK (1) | DK219178A (da) |
| ES (1) | ES470122A1 (da) |
| IT (1) | IT1080452B (da) |
| NL (1) | NL7805071A (da) |
| NO (1) | NO781792L (da) |
| PT (1) | PT68056B (da) |
| SE (1) | SE7805859L (da) |
-
1977
- 1977-05-24 IT IT03455/77A patent/IT1080452B/it active
-
1978
- 1978-05-11 NL NL7805071A patent/NL7805071A/xx not_active Application Discontinuation
- 1978-05-18 DK DK219178A patent/DK219178A/da unknown
- 1978-05-19 PT PT68056A patent/PT68056B/pt unknown
- 1978-05-23 NO NO78781792A patent/NO781792L/no unknown
- 1978-05-23 SE SE7805859A patent/SE7805859L/xx unknown
- 1978-05-23 JP JP6153078A patent/JPS53149959A/ja active Pending
- 1978-05-23 ES ES470122A patent/ES470122A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1080452B (it) | 1985-05-16 |
| PT68056A (en) | 1978-06-01 |
| JPS53149959A (en) | 1978-12-27 |
| SE7805859L (sv) | 1978-11-25 |
| ES470122A1 (es) | 1979-01-01 |
| DK219178A (da) | 1978-11-25 |
| PT68056B (en) | 1979-10-24 |
| NL7805071A (nl) | 1978-11-28 |
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