NO800723L - Fremgangsmaate til fremstilling av nye biologisk aktive tripeptider - Google Patents

Fremgangsmaate til fremstilling av nye biologisk aktive tripeptider

Info

Publication number: NO800723L
Authority: NO; Norway
Prior art keywords: polypeptides; thr; ala; procedure; preparation
Prior art date: 1979-03-14

Application number

NO800723A

Other languages

English (en)

Other versions

NO149997C (no

NO149997B (no

Inventor

Gideon Goldstein

George Heavner

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-14

Filing date

1980-03-13

Publication date

1980-09-15

1980-03-13 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1980-09-15 Publication of NO800723L publication Critical patent/NO800723L/no

1984-04-24 Publication of NO149997B publication Critical patent/NO149997B/no

1984-08-01 Publication of NO149997C publication Critical patent/NO149997C/no

Links

229920001184 polypeptide Polymers 0.000 abstract 4
102000004196 processed proteins & peptides Human genes 0.000 abstract 4
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
230000004069 differentiation Effects 0.000 abstract 3
239000000427 antigen Substances 0.000 abstract 2
102000036639 antigens Human genes 0.000 abstract 2
108091007433 antigens Proteins 0.000 abstract 2
230000002992 thymic effect Effects 0.000 abstract 2
206010010356 Congenital anomaly Diseases 0.000 abstract 1
210000001744 T-lymphocyte Anatomy 0.000 abstract 1
AYFVYJQAPQTCCC-UHFFFAOYSA-N THREONINE Chemical compound CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
210000003719 b-lymphocyte Anatomy 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
230000036039 immunity Effects 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000007935 neutral effect Effects 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
210000001541 thymus gland Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO800723A 1979-03-14 1980-03-13 Analogifremgangsmaate til fremstilling av nye terapeutisk aktive tripeptider. NO149997C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/020,159 US4215112A (en)	1979-03-14	1979-03-14	Tripeptides and methods

Publications (3)

Publication Number	Publication Date
NO800723L true NO800723L (no)	1980-09-15
NO149997B NO149997B (no)	1984-04-24
NO149997C NO149997C (no)	1984-08-01

Family

ID=21797075

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO800723A NO149997C (no)	1979-03-14	1980-03-13	Analogifremgangsmaate til fremstilling av nye terapeutisk aktive tripeptider.

Country Status (18)

Country	Link
US (1)	US4215112A (no)
EP (1)	EP0016611B1 (no)
JP (1)	JPS55143945A (no)
AT (1)	ATE4452T1 (no)
AU (1)	AU531556B2 (no)
CA (1)	CA1141375A (no)
DE (1)	DE3064559D1 (no)
DK (1)	DK149092C (no)
ES (1)	ES8103027A1 (no)
FI (1)	FI67692C (no)
GR (1)	GR68039B (no)
IE (1)	IE49289B1 (no)
IL (1)	IL59604A (no)
NO (1)	NO149997C (no)
NZ (1)	NZ193063A (no)
PT (1)	PT70936B (no)
YU (1)	YU41914B (no)
ZA (1)	ZA801482B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4298523A (en) *	1980-06-17	1981-11-03	Ortho Pharmaceutical Corporation	Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4369137A (en) *	1980-06-17	1983-01-18	Ortho Pharmaceutical Corporation	N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
US4454065A (en) *	1982-05-18	1984-06-12	Smithkline Beckman Corporation	Oligopeptide prodrugs
US4481191A (en) *	1983-03-30	1984-11-06	The Regents Of The University Of California	Method for controlling blood pressure
US4683292A (en) *	1983-08-12	1987-07-28	Immunetech, Inc.	Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors
AU602483B2 (en) *	1985-01-18	1990-10-18	Immunetech Pharmaceuticals	Immunoregulatory peptides
US4584284A (en) *	1985-01-31	1986-04-22	Ortho Pharmaceutical Corporation	Bursopoietin
IT1188646B (it) *	1986-04-09	1988-01-20	Ellem Ind Farmaceutica	Tripeptide ad attivita' immunostimolante
IT1196958B (it) *	1986-07-10	1988-11-25	Ellem Ind Farmaceutica	Derivato di timo attivo per via orale, procedimenti per la sua preparazione e relative composizioni farmaceutiche
DE68926178T2 (de) *	1988-05-10	1996-11-28	Alpha 1 Biomedicals Inc	Festphase-Verfahren zur Gewinnung von Thymosin-alpha-1
HU201964B (en) *	1989-01-13	1991-01-28	Richter Gedeon Vegyeszet	Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
KR20020019126A (ko) *	1999-08-09	2002-03-09	트리펩 아베	트리펩티드를 함유하는 약학 조성물
US6258932B1 (en) *	1999-08-09	2001-07-10	Tripep Ab	Peptides that block viral infectivity and methods of use thereof
US6593455B2 (en) *	2001-08-24	2003-07-15	Tripep Ab	Tripeptide amides that block viral infectivity and methods of use thereof
US6455670B1 (en) *	2001-09-06	2002-09-24	Tripep Ab	Pentamer peptide amide, ALGPG-NH2, that inhibits viral infectivity and methods of use thereof
WO2003024995A1 (en) *	2001-09-19	2003-03-27	Tripep Ab	Molecules that block viral infectivity and methods of use thereof
EP1603546A1 (en) *	2003-02-21	2005-12-14	Tripep AB	Glycinamide derivative for inhibiting hiv replication
US20050096319A1 (en) *	2003-02-21	2005-05-05	Balzarini Jan M.R.	Identification of compounds that inhibit replication of human immunodeficiency virus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4098777A (en) *	1977-03-14	1978-07-04	Merck & Co., Inc.	Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
FR2391994A1 (fr) *	1977-05-25	1978-12-22	Anvar	Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese
SE446866B (sv) *	1977-11-15	1986-10-13	Sloan Kettering Inst Cancer	Sett att framstella en aktiv polypeptid med formaga att inducera differentiering av bade t-lymfocyter och komplementreceptor (cr?72+) b-lymfocyter
SE446867B (sv) *	1977-11-15	1986-10-13	Sloan Kettering Inst Cancer	Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
NZ189101A (en) *	1977-12-08	1984-07-06	Ortho Pharma Corp	Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions

1979
- 1979-03-14 US US06/020,159 patent/US4215112A/en not_active Expired - Lifetime
1980
- 1980-03-06 NZ NZ193063A patent/NZ193063A/en unknown
- 1980-03-11 AU AU56312/80A patent/AU531556B2/en not_active Ceased
- 1980-03-11 GR GR61411A patent/GR68039B/el unknown
- 1980-03-12 PT PT70936A patent/PT70936B/pt unknown
- 1980-03-12 JP JP3046880A patent/JPS55143945A/ja active Pending
- 1980-03-13 DE DE8080300770T patent/DE3064559D1/de not_active Expired
- 1980-03-13 IL IL59604A patent/IL59604A/xx unknown
- 1980-03-13 NO NO800723A patent/NO149997C/no unknown
- 1980-03-13 IE IE514/80A patent/IE49289B1/en unknown
- 1980-03-13 AT AT80300770T patent/ATE4452T1/de not_active IP Right Cessation
- 1980-03-13 CA CA000347571A patent/CA1141375A/en not_active Expired
- 1980-03-13 FI FI800780A patent/FI67692C/fi not_active IP Right Cessation
- 1980-03-13 ZA ZA00801482A patent/ZA801482B/xx unknown
- 1980-03-13 ES ES489522A patent/ES8103027A1/es not_active Expired
- 1980-03-13 EP EP80300770A patent/EP0016611B1/en not_active Expired
- 1980-03-13 DK DK109280A patent/DK149092C/da active
- 1980-03-14 YU YU698/80A patent/YU41914B/xx unknown

Also Published As

Publication number	Publication date
AU531556B2 (en)	1983-08-25
YU41914B (en)	1988-02-29
JPS55143945A (en)	1980-11-10
DE3064559D1 (en)	1983-09-22
IE49289B1 (en)	1985-09-04
FI800780A7 (fi)	1980-09-15
AU5631280A (en)	1980-09-18
YU69880A (en)	1983-02-28
NO149997C (no)	1984-08-01
EP0016611A2 (en)	1980-10-01
ES489522A0 (es)	1981-02-16
NO149997B (no)	1984-04-24
DK149092C (da)	1986-06-16
DK149092B (da)	1986-01-20
ATE4452T1 (de)	1983-09-15
EP0016611B1 (en)	1983-08-17
PT70936A (en)	1980-04-01
DK109280A (da)	1980-09-15
FI67692C (fi)	1985-05-10
PT70936B (en)	1981-06-24
US4215112A (en)	1980-07-29
GR68039B (no)	1981-10-27
IL59604A0 (en)	1980-06-30
EP0016611A3 (en)	1981-01-07
IE800514L (en)	1980-09-14
CA1141375A (en)	1983-02-15
NZ193063A (en)	1984-07-06
FI67692B (fi)	1985-01-31
ZA801482B (en)	1981-10-28
IL59604A (en)	1983-02-23
ES8103027A1 (es)	1981-02-16

Publication	Publication Date	Title
NO800723L (no)	1980-09-15	Fremgangsmaate til fremstilling av nye biologisk aktive tripeptider
US4003884A (en)	1977-01-18	Peptides having LH-RH/FSH-RH activity
ATE24919T1 (de)	1987-01-15	Menschliches pankreatisches grf.
DE10075019I2 (de)	2005-06-23	Neue Proteine mit TNF-Hemmender Wirkung und ihre Herstellung.
EP0055113B1 (en)	1985-04-17	Deca- undeca- dodeca- and tridecapeptides with thymic activity, method for their preparation and compositions containing them
NO149998B (no)	1984-04-24	Analogifremgangsmaate til fremstilling av peptider med ubiquitinlignende aktivitet
Yajima et al.	1975	Synthesis of the docosapeptide corresponding to the entire amino-acid sequence of porcine motilin
EP0138616A2 (en)	1985-04-24	Nona- and dodecapeptides for augmenting natural killer cell activity, processes for making them and pharmaceutical compositions comprising them
IE800743L (en)	1980-10-12	Peptides having thymopoietin-like activity
Shenbagamurthi et al.	1985	Biological activity and conformational isomerism in position 9 analogs of the des-1-tryptophan, 3. beta.-cyclohexylalanine-. alpha.-factor from Saccharomyces cerevisiae
IE782423L (en)	1979-06-08	Tetrapeptide segment
Köhl et al.	1990	Reevaluation of the C3a active site using short synthetic C3a analogues
Ciardelli et al.	1982	Activity of synthetic thymosin. alpha. 1 C-terminal peptides in the azathioprine E-rosette inhibition assay
EP0361977A3 (en)	1991-01-09	Peptides having t cell suppressor activity
RU2136308C1 (ru)	1999-09-10	Стимулятор роста костно-мозговых клеток человека
Sofuku et al.	1986	Synthesis of gramicidin S (GS) analogs,(3-4-. DELTA. Ava)-GS and (3-4, 3'-4'-bis (. DELTA. Ava))-GS (. DELTA. Ava= 5-aminovaleric acid).
Abiko	1987	Syntheses and Structure-Activity Relationships of Thymopoietin