NO812042L - Benzopyranforbindelse samt fremgangsmaate ved fremstilling derav, og farmasoeytisk blanding inneholdende forbindelsen - Google Patents

Benzopyranforbindelse samt fremgangsmaate ved fremstilling derav, og farmasoeytisk blanding inneholdende forbindelsen

Info

Publication number
NO812042L
NO812042L NO812042A NO812042A NO812042L NO 812042 L NO812042 L NO 812042L NO 812042 A NO812042 A NO 812042A NO 812042 A NO812042 A NO 812042A NO 812042 L NO812042 L NO 812042L
Authority
NO
Norway
Prior art keywords
compound
procedures
preparing
mixture containing
benzopyrane
Prior art date
Application number
NO812042A
Other languages
English (en)
Other versions
NO154495C (no
NO154495B (no
Inventor
Masami Shiratsuchi
Noboru Shimizu
Yoshinori Kyotani
Hisashi Kunieda
Seiichi Sato
Toshihiro Akashi
Hiromichi Shigyo
Kiyoshi Kawamura
Masaniko Nagakura
Naotoshi Sawada
Yasum Uchida
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8084180A external-priority patent/JPS6054317B2/ja
Priority claimed from JP55182854A external-priority patent/JPS57106619A/ja
Application filed by Kowa Co filed Critical Kowa Co
Publication of NO812042L publication Critical patent/NO812042L/no
Publication of NO154495B publication Critical patent/NO154495B/no
Publication of NO154495C publication Critical patent/NO154495C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO812042A 1980-06-17 1981-06-16 Analogifremgangsmaate for fremstilling av en benzopyranforbindelse. NO154495C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8084180A JPS6054317B2 (ja) 1980-06-17 1980-06-17 新規ベンゾピラン誘導体
JP55182854A JPS57106619A (en) 1980-12-25 1980-12-25 Remedy for circulatory disease

Publications (3)

Publication Number Publication Date
NO812042L true NO812042L (no) 1981-12-18
NO154495B NO154495B (no) 1986-06-23
NO154495C NO154495C (no) 1986-10-01

Family

ID=26421809

Family Applications (1)

Application Number Title Priority Date Filing Date
NO812042A NO154495C (no) 1980-06-17 1981-06-16 Analogifremgangsmaate for fremstilling av en benzopyranforbindelse.

Country Status (16)

Country Link
US (1) US4394382A (no)
EP (1) EP0042299B1 (no)
KR (1) KR850000193B1 (no)
AU (1) AU543347B2 (no)
CA (1) CA1178598A (no)
CS (1) CS226731B2 (no)
DD (1) DD160453A5 (no)
DE (1) DE3166300D1 (no)
DK (1) DK154557C (no)
ES (1) ES503091A0 (no)
FI (1) FI79307C (no)
IE (1) IE52067B1 (no)
NO (1) NO154495C (no)
PL (1) PL130537B1 (no)
SU (1) SU1212325A3 (no)
ZA (1) ZA814042B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5965076A (ja) * 1982-10-05 1984-04-13 Kowa Co 新規なキノリン誘導体
JPS60181083A (ja) * 1984-02-29 1985-09-14 Kowa Co 新規ラセミ体及びその変換方法
JPS60208973A (ja) * 1984-03-31 1985-10-21 Kowa Co 循環系疾患治療剤
GB8730051D0 (en) * 1987-12-23 1988-02-03 Beecham Group Plc Novel compounds
DK0901483T3 (da) * 1996-05-14 2003-11-03 Glaxo Group Ltd Benzofuraner og benzopyraner som kronobiologiske midler
JP4000505B2 (ja) 1999-12-01 2007-10-31 第一三共株式会社 緑内障を治療するための併用剤
EA200500234A1 (ru) 2002-08-19 2005-08-25 Пфайзер Продактс Инк. Комбинированная терапия гиперпролиферативных болезней
WO2004037246A1 (ja) * 2002-10-24 2004-05-06 Kowa Co., Ltd. 神経線維再生促進剤
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
TWI646091B (zh) * 2012-12-28 2019-01-01 日商衛斯克慧特股份有限公司 鹽類及晶形
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1493998A (en) * 1975-06-03 1977-12-07 Beecham Group Ltd Propanolamine derivatives
JPS54106476A (en) * 1978-01-04 1979-08-21 Merck & Co Inc Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine
DE2804625A1 (de) * 1978-02-03 1979-08-09 Thomae Gmbh Dr K Neue 4-acylamino-phenyl-aethanolamine
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DD160453A5 (de) 1983-08-03
PL130537B1 (en) 1984-08-31
EP0042299A1 (en) 1981-12-23
AU7165281A (en) 1981-12-24
US4394382A (en) 1983-07-19
NO154495C (no) 1986-10-01
FI79307B (fi) 1989-08-31
AU543347B2 (en) 1985-04-18
DK154557C (da) 1989-04-17
EP0042299B1 (en) 1984-09-26
ZA814042B (en) 1982-06-30
KR830006268A (ko) 1983-09-20
CA1178598A (en) 1984-11-27
SU1212325A3 (ru) 1986-02-15
FI811856L (fi) 1981-12-18
DE3166300D1 (en) 1984-10-31
DK154557B (da) 1988-11-28
ES8300104A1 (es) 1982-10-01
PL231734A1 (no) 1982-08-16
FI79307C (fi) 1989-12-11
KR850000193B1 (ko) 1985-03-05
CS226731B2 (en) 1984-04-16
NO154495B (no) 1986-06-23
IE811312L (en) 1981-12-17
ES503091A0 (es) 1982-10-01
DK264181A (da) 1981-12-18
IE52067B1 (en) 1987-06-10

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Legal Events

Date Code Title Description
MK1K Patent expired

Free format text: EXPIRED IN JUNE 2001