NO813700L - 2,6-d-dimetyltyrosin1-d-aminosyre2-epsilon-aminokapronsyre- og gamma-aminosmoersyrederivater av metioninenkefalin, og fremgangsmaate for deres fremstilling - Google Patents

2,6-d-dimetyltyrosin1-d-aminosyre2-epsilon-aminokapronsyre- og gamma-aminosmoersyrederivater av metioninenkefalin, og fremgangsmaate for deres fremstilling

Info

Publication number
NO813700L
NO813700L NO813700A NO813700A NO813700L NO 813700 L NO813700 L NO 813700L NO 813700 A NO813700 A NO 813700A NO 813700 A NO813700 A NO 813700A NO 813700 L NO813700 L NO 813700L
Authority
NO
Norway
Prior art keywords
acid
amino
compound according
preparation
mmol
Prior art date
Application number
NO813700A
Other languages
English (en)
Norwegian (no)
Inventor
David Ackley Jones
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO813700L publication Critical patent/NO813700L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO813700A 1980-11-03 1981-11-02 2,6-d-dimetyltyrosin1-d-aminosyre2-epsilon-aminokapronsyre- og gamma-aminosmoersyrederivater av metioninenkefalin, og fremgangsmaate for deres fremstilling NO813700L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/202,920 US4316892A (en) 1980-11-03 1980-11-03 2,6-C-Dimethyltyrosine1 -D-amino acid2 -ε-amino caproic and γ aminobutyric acid5 derivatives of methionine enkephalin

Publications (1)

Publication Number Publication Date
NO813700L true NO813700L (no) 1982-05-04

Family

ID=22751754

Family Applications (1)

Application Number Title Priority Date Filing Date
NO813700A NO813700L (no) 1980-11-03 1981-11-02 2,6-d-dimetyltyrosin1-d-aminosyre2-epsilon-aminokapronsyre- og gamma-aminosmoersyrederivater av metioninenkefalin, og fremgangsmaate for deres fremstilling

Country Status (18)

Country Link
US (1) US4316892A (fr)
JP (1) JPS57131748A (fr)
AU (1) AU546107B2 (fr)
BE (1) BE890963A (fr)
CA (1) CA1178577A (fr)
CH (1) CH649562A5 (fr)
DE (1) DE3143599A1 (fr)
DK (1) DK483481A (fr)
ES (1) ES8306474A1 (fr)
FR (1) FR2493311B1 (fr)
GB (1) GB2086912B (fr)
IT (1) IT1195324B (fr)
NL (1) NL8104976A (fr)
NO (1) NO813700L (fr)
NZ (1) NZ198862A (fr)
PT (1) PT73915B (fr)
SE (1) SE446986B (fr)
ZA (1) ZA817592B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603121A (en) * 1983-10-06 1986-07-29 G. D. Searle & Co. Enkephalin analogs
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
US4599325A (en) * 1984-02-16 1986-07-08 G. D. Searle & Co. Substituted tyrosyl alanine dipeptide amides
EP0215297A3 (fr) * 1985-08-14 1989-07-19 G.D. Searle & Co. Amides dipeptides substitués
US4880829A (en) * 1985-08-14 1989-11-14 G. D. Searle And Company Substituted dipeptide amides #3
US4760180A (en) * 1986-02-14 1988-07-26 G. D. Searle & Co. N-terminally substituted dipeptide amides
US4757153A (en) * 1986-02-14 1988-07-12 G. D. Searle & Co. Sulfide, sulfinyl and sulfone dipeptide amides
US4822775A (en) * 1986-02-14 1989-04-18 G. D. Searle & Co. Phenyl substituted dipeptide amides
ES2061442T3 (es) * 1985-10-14 1994-12-16 Nippon Zoki Pharmaceutical Co Peptidos.
US4797470A (en) * 1986-07-14 1989-01-10 G. D. Searle & Co. O-substituted tyrosyl dipeptide amides
US4758675A (en) * 1986-07-14 1988-07-19 G. D. Searle & Co. 3-thiophene-substituted tyrosyl dipeptide amides
US4767744A (en) * 1986-07-14 1988-08-30 G. D. Searle & Co. Substituted tyrosyl methionyl dipeptide amides
EP1575390B1 (fr) * 2002-12-03 2008-03-26 Velcro Industries B.V. Aiguilletage de substrats destine a la formation de bouclettes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178371A (en) * 1977-12-15 1979-12-11 Reckitt & Colman Products Limited Tetrapeptide derivatives
US4261883A (en) * 1979-07-09 1981-04-14 The Regents Of The University Of California Novel N-aralkyl enkephalin amide analogs are provided having analgesic and opioid properties
JPS6038400B2 (ja) * 1979-08-10 1985-08-31 株式会社 大塚製薬工場 エンケファリン誘導体の製造法

Also Published As

Publication number Publication date
AU546107B2 (en) 1985-08-15
AU7702481A (en) 1982-05-13
PT73915B (en) 1983-04-29
SE8106441L (sv) 1982-05-04
CH649562A5 (de) 1985-05-31
FR2493311A1 (fr) 1982-05-07
US4316892A (en) 1982-02-23
IT8149623A0 (it) 1981-11-03
IT8149623A1 (it) 1983-05-03
BE890963A (fr) 1982-03-01
NL8104976A (nl) 1982-06-01
ES506783A0 (es) 1983-06-01
ZA817592B (en) 1982-10-27
ES8306474A1 (es) 1983-06-01
GB2086912B (en) 1984-03-21
PT73915A (en) 1981-12-01
NZ198862A (en) 1985-09-13
FR2493311B1 (fr) 1986-04-25
DE3143599A1 (de) 1982-08-05
CA1178577A (fr) 1984-11-27
SE446986B (sv) 1986-10-20
DK483481A (da) 1982-05-04
IT1195324B (it) 1988-10-12
GB2086912A (en) 1982-05-19
JPS57131748A (en) 1982-08-14

Similar Documents

Publication Publication Date Title
Gisin et al. Solid-phase synthesis of the cyclododecadepsipeptide valinomycin
US6350760B1 (en) Substituted piperidines as melanocortin-4 receptor agonists
US6410548B2 (en) Spiropiperidine derivatives as melanocortin receptor agonists
US6472398B1 (en) Spiropiperidine derivatives as melanocortin receptor agonists
US5317014A (en) Peptides and pseudopeptides derived from tachykinin
US20020004512A1 (en) Melanocortin receptor agonists
JPH072894A (ja) ドラスタチン１０誘導体
AU2001288285A1 (en) Substituted piperidines as melanocortin receptor agonists
NZ191434A (en) N2-aryl sulphonyl-l-argininamides and pharmaceutical compositions
FI70228C (fi) Foerfarande foer framstaellning av en enkefalin-analog-peptid
JPH0811746B2 (ja) 新規ペプチド化合物
CA1178577A (fr) Derives acides 2,6-c-dimethyltyrosine.sup.1-d- amino acide.sup.2-epsilone-amino caproique et gamma aminobutyrique de la methionine encephaline
CA2124989A1 (fr) Peptide antagoniste de l'endotheline
HU182866B (en) Process for preparing new tetrapeptide derivatives
GB1577115A (en) Container closure units
JPS61229851A (ja) ペプチド化合物
US4405607A (en) Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
US5494898A (en) Peptide skeletal muscle relaxants
DE69511259T2 (de) N-amidino- dermorphin-derivat
RU2161501C1 (ru) Способ получения пептидов, обладающих тканеспецифической активностью, и фармацевтические композиции на их основе
US6051685A (en) Peptide derivatives
HU203770B (en) Process for producing histidine derivatives and pharmaceutical compositions containing them as active components
US6228841B1 (en) Peptide derivatives
EP0099057B1 (fr) Dérivés N-acylés de peptides, leur préparation et utilisation dans la lutte contre les maladies et moyen de lutte
HU205769B (en) Process for producing renin inhibiting tri- and tetrapeptides and pharmaceutical compositions comprising same