NO821180L - Fremgangsmaate ved fremstilling av nye prostaglandin- og prostacyclinderivater. - Google Patents

Fremgangsmaate ved fremstilling av nye prostaglandin- og prostacyclinderivater.

Info

Publication number
NO821180L
NO821180L NO821180A NO821180A NO821180L NO 821180 L NO821180 L NO 821180L NO 821180 A NO821180 A NO 821180A NO 821180 A NO821180 A NO 821180A NO 821180 L NO821180 L NO 821180L
Authority
NO
Norway
Prior art keywords
denotes
hydroxy
oxazolin
butyl
hydrogen
Prior art date
Application number
NO821180A
Other languages
English (en)
Norwegian (no)
Inventor
Helmut Vorbrueggen
Walter Elger
Michael-Harold Town
Ekkehard Schillinger
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19813115997 external-priority patent/DE3115997A1/de
Priority claimed from DE19813145830 external-priority patent/DE3145830A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO821180L publication Critical patent/NO821180L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO821180A 1981-04-13 1982-04-07 Fremgangsmaate ved fremstilling av nye prostaglandin- og prostacyclinderivater. NO821180L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813115997 DE3115997A1 (de) 1981-04-13 1981-04-13 "neue prostaglandine und prostacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel"
DE19813145830 DE3145830A1 (de) 1981-11-13 1981-11-13 Neue prostacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
NO821180L true NO821180L (no) 1982-10-14

Family

ID=25792821

Family Applications (1)

Application Number Title Priority Date Filing Date
NO821180A NO821180L (no) 1981-04-13 1982-04-07 Fremgangsmaate ved fremstilling av nye prostaglandin- og prostacyclinderivater.

Country Status (19)

Country Link
US (2) US4468395A (cs)
EP (1) EP0063538B1 (cs)
AU (1) AU560180B2 (cs)
CA (1) CA1215974A (cs)
CS (1) CS256374B2 (cs)
DD (1) DD202429A5 (cs)
DE (1) DE3272423D1 (cs)
DK (1) DK151881C (cs)
ES (1) ES511252A0 (cs)
FI (1) FI821248A7 (cs)
GR (1) GR75470B (cs)
HU (1) HU191357B (cs)
IE (1) IE53056B1 (cs)
IL (1) IL65484A (cs)
MX (1) MX157260A (cs)
NO (1) NO821180L (cs)
NZ (1) NZ200257A (cs)
PH (1) PH21292A (cs)
YU (1) YU80482A (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063538B1 (de) * 1981-04-13 1986-08-06 Schering Aktiengesellschaft Neue Prostaglandine und Prostacycline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
US5399757A (en) * 1993-07-20 1995-03-21 Ortho Pharmaceutical Corporation Process for the preparation of N-(4-hydroxyphenyl)-retinamide
US7776896B2 (en) * 2007-03-28 2010-08-17 Bayer Schering Pharma Aktiengesellschaft 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2038333B (en) * 1978-01-26 1982-10-06 Erba Farmitalia 12 -formyl- (20 12)octanor-9-deoxy-9 -methylene pgi derivatives
DE2907118A1 (de) * 1979-02-20 1980-09-04 Schering Ag Neue prostacyclin-derivate und verfahren zu ihrer herstellung
US4294759A (en) * 1979-11-15 1981-10-13 The Upjohn Company Structural analogues of 5,6,-dihydro PG1
DE3006865A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Hetero-imino-prostacycline
DE3047759A1 (de) * 1980-12-15 1982-07-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur herstellung von (delta)(pfeil hoch)2(pfeil hoch)-n-heterocyclen
EP0063538B1 (de) * 1981-04-13 1986-08-06 Schering Aktiengesellschaft Neue Prostaglandine und Prostacycline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
ES8303325A1 (es) 1983-02-16
US4468395A (en) 1984-08-28
DD202429A5 (de) 1983-09-14
HU191357B (en) 1987-02-27
NZ200257A (en) 1985-08-30
CA1215974A (en) 1986-12-30
AU8250482A (en) 1983-04-21
AU560180B2 (en) 1987-04-02
YU80482A (en) 1984-12-31
PH21292A (en) 1987-09-28
CS256374B2 (en) 1988-04-15
DK164382A (da) 1982-10-14
DE3272423D1 (en) 1986-09-11
FI821248L (fi) 1982-10-14
GR75470B (cs) 1984-07-23
CS256382A2 (en) 1987-08-13
FI821248A7 (fi) 1982-10-14
FI821248A0 (fi) 1982-04-07
IE820849L (en) 1982-10-13
US4631276A (en) 1986-12-23
DK151881B (da) 1988-01-11
IL65484A (en) 1986-02-28
IL65484A0 (en) 1982-07-30
MX157260A (es) 1988-11-09
DK151881C (da) 1988-07-04
EP0063538B1 (de) 1986-08-06
EP0063538A2 (de) 1982-10-27
ES511252A0 (es) 1983-02-16
EP0063538A3 (en) 1983-03-16
IE53056B1 (en) 1988-05-25

Similar Documents

Publication Publication Date Title
DK170889B1 (da) 9-halogen-prostanderivater og lægemidler indeholdende dem
US4692464A (en) Novel prostacyclin derivatives and a process for the preparation thereof
US4708963A (en) Novel carbacyclins, their preparation and use
US4699920A (en) 9-halo-2-prostaglandin derivatives, processes for the preparation thereof and use thereof as medicinal agents
US4219479A (en) 5-Cyano-prostacyclin derivatives
US4073934A (en) Novel acetylenic prostaglandin analogs
US4191694A (en) Prostaglandin-I2 derivatives
DK154073B (da) 9-fluor-prostaglandinderivater
US4364951A (en) Prostacyclins and use as medicinal agents
IE831630L (en) Carbacyclin derivatives
US4954524A (en) Carbacylcins, their preparation and use as medicinal agents
US4631276A (en) Prostaglandins and prostacyclins, process for their preparation and their use as medicaments
US4346228A (en) Novel 11-oxoprostaglandin derivatives
US4315013A (en) Certain pyrrole analogs of prostacyclin derivatives
US4466969A (en) 7-Oxoprostacyclin derivatives and their use as hypotensives and bronchodilators
US5891910A (en) 9-halogen-(Z) prostaglandin derivatives, process for their production and their use as pharmaceutical agents
US4532236A (en) Certain prostacyclins and their blood-pressure-lowering and thrombocyte-aggregation-inhibiting compositions and methods
IE73875B1 (en) Cyclopentane ether derivatives process for their production and their pharmaceutical usage
US5157042A (en) 3-oxa-5-fluoro-carbacyclins, their preparation and use as medicinal agents
US5190964A (en) 5-fluorocarbacyclins, their preparation and pharmaceutical use
DE3115997A1 (de) "neue prostaglandine und prostacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel"
IE69970B1 (en) Bicyclo [3.3.0] octane derivatives process for their production and their pharmaceutical use
IE73476B1 (en) Cyclopentane derivatives process for their production and their pharmaceutical use
HU190901B (en) Process for preparing new carbacycline derivatives and pharmaceutical preparations comprising these compounds