NO831995L - Analogifremgangsmaate for fremstilling av terapeutisk aktive n-(2-metoksyetyl)-noroksymorfon - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive n-(2-metoksyetyl)-noroksymorfon

Info

Publication number
NO831995L
NO831995L NO831995A NO831995A NO831995L NO 831995 L NO831995 L NO 831995L NO 831995 A NO831995 A NO 831995A NO 831995 A NO831995 A NO 831995A NO 831995 L NO831995 L NO 831995L
Authority
NO
Norway
Prior art keywords
metoxythyl
noroxymorphone
preparation
therapeutic active
analogy procedure
Prior art date
Application number
NO831995A
Other languages
English (en)
Other versions
NO158579B (no
NO158579C (no
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO831995L publication Critical patent/NO831995L/no
Publication of NO158579B publication Critical patent/NO158579B/no
Publication of NO158579C publication Critical patent/NO158579C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO831995A 1982-06-03 1983-06-02 Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-(2-metoksyetyl)-noroksymorfon. NO158579C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823220831 DE3220831A1 (de) 1982-06-03 1982-06-03 N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (3)

Publication Number Publication Date
NO831995L true NO831995L (no) 1983-12-05
NO158579B NO158579B (no) 1988-06-27
NO158579C NO158579C (no) 1988-10-05

Family

ID=6165151

Family Applications (1)

Application Number Title Priority Date Filing Date
NO831995A NO158579C (no) 1982-06-03 1983-06-02 Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-(2-metoksyetyl)-noroksymorfon.

Country Status (27)

Country Link
US (1) US4473573A (no)
EP (1) EP0096279B1 (no)
JP (1) JPS591487A (no)
KR (1) KR900006754B1 (no)
AU (1) AU558319B2 (no)
CA (1) CA1196633A (no)
CS (1) CS236882B2 (no)
CZ (1) CZ410691A3 (no)
DD (1) DD209834A5 (no)
DE (2) DE3220831A1 (no)
DK (1) DK156068C (no)
ES (1) ES8403487A1 (no)
FI (1) FI78101C (no)
GB (1) GB2121041B (no)
GR (1) GR78273B (no)
HK (1) HK1389A (no)
HU (1) HU185832B (no)
IE (1) IE55232B1 (no)
IL (1) IL68872A0 (no)
NO (1) NO158579C (no)
NZ (1) NZ204451A (no)
PH (1) PH19518A (no)
PL (1) PL139569B1 (no)
PT (1) PT76805B (no)
SG (1) SG58788G (no)
SU (1) SU1195909A3 (no)
ZA (1) ZA833981B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132159A1 (de) * 1991-09-27 1993-04-01 Boehringer Ingelheim Kg 14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphin und -norisomorphin, verfahren zu deren herstellung und deren verwendung als arzneimittel
RU2215741C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Сложные эфиры n-замещенных 14-гидроксиморфинанов и способ их получения
RU2215742C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Способ получения сложных эфиров n-замещенных 14-гидроксиморфинанов
US9119848B2 (en) 2009-12-04 2015-09-01 Alkermes Pharma Ireland Limited Morphinan derivatives for the treatment of drug overdose
HUE065427T2 (hu) 2010-08-23 2024-05-28 Alkermes Pharma Ireland Ltd Eljárások antipszichotikum által indukált súlygyarapodás kezelésére
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
CA2911231C (en) 2013-05-24 2021-12-07 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
DE2538075A1 (de) * 1975-08-27 1977-03-17 Boehringer Sohn Ingelheim N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DK250783D0 (da) 1983-06-02
SU1195909A3 (ru) 1985-11-30
DE3220831A1 (de) 1983-12-08
PT76805B (de) 1986-04-09
CA1196633A (en) 1985-11-12
PL139569B1 (en) 1987-02-28
NO158579B (no) 1988-06-27
NZ204451A (en) 1986-07-11
JPS591487A (ja) 1984-01-06
NO158579C (no) 1988-10-05
GR78273B (no) 1984-09-26
ZA833981B (en) 1985-01-30
ES522897A0 (es) 1984-03-16
CS236882B2 (en) 1985-05-15
IE831299L (en) 1983-12-03
IL68872A0 (en) 1983-10-31
DK156068B (da) 1989-06-19
HK1389A (en) 1989-01-13
IE55232B1 (en) 1990-07-04
FI78101C (fi) 1989-06-12
FI78101B (fi) 1989-02-28
DD209834A5 (de) 1984-05-23
EP0096279A1 (de) 1983-12-21
AU558319B2 (en) 1987-01-29
DK156068C (da) 1989-11-06
PT76805A (de) 1983-07-01
FI831941L (fi) 1983-12-04
SG58788G (en) 1989-03-10
FI831941A0 (fi) 1983-05-31
JPH0373552B2 (no) 1991-11-22
CZ410691A3 (en) 1993-02-17
PL242312A1 (en) 1985-04-09
AU1531483A (en) 1983-12-08
GB2121041A (en) 1983-12-14
US4473573A (en) 1984-09-25
DK250783A (da) 1983-12-04
PH19518A (en) 1986-05-14
ES8403487A1 (es) 1984-03-16
GB2121041B (en) 1985-09-11
HU185832B (en) 1985-04-28
KR840005146A (ko) 1984-11-03
KR900006754B1 (ko) 1990-09-20
DE3361165D1 (en) 1985-12-12
EP0096279B1 (de) 1985-11-06
GB8315292D0 (en) 1983-07-06

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