NO832630L - Trifenylimidazolyloxyalkansyrer og deres derivater, deres fremstilling og deres anvendelse i preparater - Google Patents

Trifenylimidazolyloxyalkansyrer og deres derivater, deres fremstilling og deres anvendelse i preparater

Info

Publication number
NO832630L
NO832630L NO832630A NO832630A NO832630L NO 832630 L NO832630 L NO 832630L NO 832630 A NO832630 A NO 832630A NO 832630 A NO832630 A NO 832630A NO 832630 L NO832630 L NO 832630L
Authority
NO
Norway
Prior art keywords
acids
trifenylimidazolyloxyalkanic
preparations
derivatives
preparation
Prior art date
Application number
NO832630A
Other languages
English (en)
Other versions
NO160579B (no
NO160579C (no
Inventor
Hans-Heiner Lautenschlaeger
Andre Welter
Gerd Hilboll
Johannes Winkelmann
Gerrit Prop
Axel Brekle
Ottfried Zierenberg
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of NO832630L publication Critical patent/NO832630L/no
Publication of NO160579B publication Critical patent/NO160579B/no
Publication of NO160579C publication Critical patent/NO160579C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO832630A 1982-07-29 1983-07-19 Analogifremgangsmaate for fremstilling av terapeutisk aktive omega-(1,4,5-trifenylimidazol-2-yloksy)-alkansyrer og disses derivater. NO160579C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3228271A DE3228271A1 (de) 1982-07-29 1982-07-29 Triphenylimidazolyloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (3)

Publication Number Publication Date
NO832630L true NO832630L (no) 1984-01-30
NO160579B NO160579B (no) 1989-01-23
NO160579C NO160579C (no) 1989-05-03

Family

ID=6169571

Family Applications (1)

Application Number Title Priority Date Filing Date
NO832630A NO160579C (no) 1982-07-29 1983-07-19 Analogifremgangsmaate for fremstilling av terapeutisk aktive omega-(1,4,5-trifenylimidazol-2-yloksy)-alkansyrer og disses derivater.

Country Status (13)

Country Link
US (1) US4460598A (no)
EP (1) EP0104342B1 (no)
JP (1) JPS5951269A (no)
AT (1) ATE25246T1 (no)
DE (2) DE3228271A1 (no)
DK (1) DK158723C (no)
ES (1) ES8404332A1 (no)
FI (1) FI79302C (no)
GR (1) GR78654B (no)
IE (1) IE55485B1 (no)
NO (1) NO160579C (no)
PT (1) PT77125B (no)
ZA (1) ZA834648B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3323870A1 (de) * 1983-07-02 1985-01-03 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-ylthioalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
DE3504678A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazolyl-oxyalkansaeuren und -thioalkansaeuren, ihre derivate und verfahren zu ihrer herstellung
DE3504679A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Amide der 2-imidazolyloxyalkansaeuren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504677A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504680A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue ether des 2-hydroxyimidazols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPH0680057B2 (ja) * 1986-04-28 1994-10-12 保土谷化学工業株式会社 トリフエニルイミダゾ−ル及びその二量体
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.
US4900744A (en) * 1988-09-14 1990-02-13 E. I. Du Pont De Nemours And Company Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles
US5166214A (en) * 1988-12-05 1992-11-24 Du Pont Merck Pharmaceutical Company Use of imidazoles for the treatment of atherosclerosis
CA2014537A1 (en) * 1989-04-26 1990-10-26 Yoshio Hayashi 4-imidazoline derivatives
US4994482A (en) * 1989-07-31 1991-02-19 Bristol-Myers Squibb Company Arylpyrazol derivatives as anti-platelet agents, compositions and use
US5019572A (en) * 1990-02-07 1991-05-28 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5262540A (en) * 1989-12-20 1993-11-16 Bristol-Myers Squibb Company [2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters
US5152988A (en) * 1990-02-07 1992-10-06 Merck & Co., Inc. Imidazole compounds in compositions and methods in thrombolytic therapy
CA2036192A1 (en) 1990-02-13 1991-08-14 Nicholas Meanwell Heterocyclic carboxylic acids and esters
US5011851A (en) * 1990-02-13 1991-04-30 Bristol-Myers Squibb Co. Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
GB9019838D0 (en) * 1990-09-11 1990-10-24 Smith Kline French Lab Compounds
US5428041A (en) * 1991-05-31 1995-06-27 The Du Pont Merck Pharmaceutical Company Antihypercholesterolemic bis-trifluoromethyl-substituted imidazolines and derivatives thereof
US5179117A (en) * 1991-12-20 1993-01-12 Du Pont Merck Pharmaceutical Company Antihypercholesterolemic 2-substituted imidazoles
JP2001527506A (ja) * 1992-02-11 2001-12-25 スミスクライン・ビーチャム・コーポレイション ＣｏＡ−ＩＴおよびＰＡＦ阻害剤
US5254576A (en) * 1992-04-03 1993-10-19 Bristol-Myers Squibb Company Diphenyl-heterocyclic-oxazole as platelet aggregation inhibitors
US5348969A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Diphenyloxazolyl-oxazoles as platelet aggregation inhibitors
US5187188A (en) * 1992-04-03 1993-02-16 Bristol-Myers Squibb Company Oxazole carboxylic acid derivatives
US5310748A (en) * 1992-05-11 1994-05-10 The Du Pont Merck Pharmaceutical Company Imidazoles for the treatment of atherosclerosis
US5364875A (en) * 1992-05-11 1994-11-15 The Du Pont Merck Pharmaceutical Company Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis
US5362879A (en) * 1993-04-15 1994-11-08 Bristol-Myers Squibb Company 4-5-diphenyloxazole derivatives as inhibitors of blood platelet aggregation
SE527381C3 (sv) * 2003-04-14 2006-03-21 Linnman Elektronik Ab Gemensam fältbuss för överföring av data och energi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
DE2934746A1 (de) * 1979-08-28 1981-03-19 A. Nattermann & Cie GmbH, 5000 Köln Oxoimidazolinalkansaeuren, deren salze und ester sowie verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2950478A1 (de) * 1979-12-14 1981-06-19 A. Nattermann & Cie GmbH, 5000 Köln 4,5-diaryl-4-imidazolin-2-on-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3042466A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
FI79302B (fi) 1989-08-31
DK346783A (da) 1984-01-30
IE55485B1 (en) 1990-09-26
IE831483L (en) 1983-12-29
FI79302C (fi) 1989-12-11
NO160579B (no) 1989-01-23
DK158723B (da) 1990-07-09
FI832730L (fi) 1984-01-30
GR78654B (no) 1984-09-27
NO160579C (no) 1989-05-03
DE3228271A1 (de) 1984-02-02
JPH0456030B2 (no) 1992-09-07
EP0104342B1 (de) 1987-01-28
JPS5951269A (ja) 1984-03-24
PT77125B (en) 1986-01-24
FI832730A0 (fi) 1983-07-28
ES524512A0 (es) 1984-04-16
PT77125A (en) 1983-08-01
ATE25246T1 (de) 1987-02-15
DK346783D0 (da) 1983-07-28
DK158723C (da) 1990-12-10
EP0104342A1 (de) 1984-04-04
ES8404332A1 (es) 1984-04-16
DE3369508D1 (en) 1987-03-05
ZA834648B (en) 1984-03-28
US4460598A (en) 1984-07-17

Similar Documents

Publication Publication Date Title
DK346783A (da) Triphenylimidazolyloxyalkansyrer og derivater deraf, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse forbindelser
DK505983D0 (da) Imidazolylalkylthienyl-tetrahydropyridaziner og fremgangsmade til fremstilling deraf
IT1127253B (it) Proteine purificate e procedimento per la loro preparazione
FI883249A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 3-desmetyylimevalonihappojohdannaisten valmistamiseksi
EA199900494A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
IT1123519B (it) Procedimento per la preparazione di tetrafluoroetano
FI913943A0 (fi) Nya kroman- och tiokromanderivat.
DE3377063D1 (en) Benzisoselenazolones, process for their preparation and pharmaceutical compositions containing them
BE872336A (fr) Procede d'elimination des sucres flatulents de soja
IT8009551A0 (it) E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus
DK162439C (da) Imidazol-2-ylthioalkansyrer og derivater deraf, fremgangsmaader til deres fremstilling samt farmaceutiske praeparater indeholdende disse
BG38489A3 (en) Method for preparing oxazophosphorine- 6, 4- thiolcalsulphonic acids and their neutral salts
FI88401B (fi) Foerfarande foer framstaellning av peptider med inverkan pao diures och natriures
PT87642A (pt) Process for the preparation of dopamine-beta-hydroxylase inhibitors
DK39084D0 (da) 2-imino-pyrrolidiner, fremgangsmade til deres fremstilling og terapeutiske midler indeholdende dem
DE3371515D1 (en) Cycloalkyl derivatives of benzisoselenazolones, process for their preparation and pharmaceutical compositions containing them
SE7902866L (sv) 3-0-(beta-d-glukuronopyranosyl)-sojasapogenol b
IT1125487B (it) Procedimento perfezionato per la preparazione di idroperossidi aromatici
DK243280A (da) 3,4,5-trihydroxypiperidinderivater deres fremstilling og anvendelse
DE3277971D1 (en) Acylamino-4-aza-1-adamantanes, process for their preparation and their therapeutic use
IT7927484A0 (it) Procedimento per l'incisione disuperfici di pezzi mediante attacco chimico.
FI803305A7 (fi) Menetelmä uusien sulfonihapposykloalkyyliamidien valmistamiseksi ja niiden käyttö mikromikrobeja tuhoavina aineina.
IT1101712B (it) Procedimento perfezionato per la preparazione di guaiacolo acetil-salicilato
PT88294A (pt) Processo para a preparacao de derivados de fenantridina
IT7924615A0 (it) Triciclazolo. procedimento per la preparazione di