NO832848L - Gjaerhybridvektorer og deres bruk ved fremstillingen av polypeptider - Google Patents

Gjaerhybridvektorer og deres bruk ved fremstillingen av polypeptider

Info

Publication number
NO832848L
NO832848L NO832848A NO832848A NO832848L NO 832848 L NO832848 L NO 832848L NO 832848 A NO832848 A NO 832848A NO 832848 A NO832848 A NO 832848A NO 832848 L NO832848 L NO 832848L
Authority
NO
Norway
Prior art keywords
hybrid vectors
yeast
preparation
promoter
polypeptides
Prior art date
Application number
NO832848A
Other languages
English (en)
Other versions
NO172548C (no
NO172548B (no
Inventor
Albert Hinnen
Bernd Meyhack
Francois Meyer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838315145A external-priority patent/GB8315145D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO832848L publication Critical patent/NO832848L/no
Publication of NO172548B publication Critical patent/NO172548B/no
Publication of NO172548C publication Critical patent/NO172548C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Alcoholic Beverages (AREA)
NO832848A 1982-08-09 1983-08-08 Saccharomyces cerevisiae hybride vektorer og anvendelse av disse ved fremstilling av polypeptider NO172548C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8222883 1982-08-09
GB8237026 1982-12-31
GB838315145A GB8315145D0 (en) 1982-08-09 1983-06-02 Yeast hybrid vectors

Publications (3)

Publication Number Publication Date
NO832848L true NO832848L (no) 1984-02-10
NO172548B NO172548B (no) 1993-04-26
NO172548C NO172548C (no) 1993-08-04

Family

ID=27261693

Family Applications (1)

Application Number Title Priority Date Filing Date
NO832848A NO172548C (no) 1982-08-09 1983-08-08 Saccharomyces cerevisiae hybride vektorer og anvendelse av disse ved fremstilling av polypeptider

Country Status (20)

Country Link
EP (1) EP0100561B1 (no)
JP (2) JPH0653073B2 (no)
AT (1) ATE43636T1 (no)
AU (1) AU566348B2 (no)
CA (1) CA1341381C (no)
CY (1) CY1451A (no)
DD (1) DD218118A5 (no)
DE (1) DE3379960D1 (no)
DK (1) DK174905B1 (no)
ES (3) ES8505724A1 (no)
FI (1) FI80720C (no)
GB (1) GB2125047B (no)
GR (1) GR78924B (no)
HK (1) HK90688A (no)
HU (1) HU204095B (no)
IE (1) IE55598B1 (no)
NO (1) NO172548C (no)
NZ (1) NZ205178A (no)
PH (1) PH25617A (no)
PT (1) PT77167B (no)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
DE3381566D1 (de) * 1982-08-16 1990-06-21 Agency Science & Tech Hepatitis-b-virus-gen enthaltendes rekombinantes plasmid, mit diesem rekombinanten plasmid transformierte hefe und herstellung von hepatitis-b-virus-oberflaechenantigen.
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
IL69202A (en) * 1982-09-08 1991-08-16 Smith Kline Rit Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof
JPS5974988A (ja) * 1982-10-20 1984-04-27 Suntory Ltd 酵母の誘導発現型プラスミドベクタ−およびその利用方法
ZA843275B (en) * 1983-05-05 1984-12-24 Hoffmann La Roche Novel vectors for interferon expression
DE3479520D1 (en) * 1983-11-21 1989-09-28 Ciba Geigy Ag Synthesis of tissue plasminogen activator(tpa) by yeast
JPS60248181A (ja) * 1984-05-23 1985-12-07 Shiseido Co Ltd 酵母発現ベクタ−
US5723292A (en) * 1984-05-25 1998-03-03 Zymogenetics, Inc. Stable DNA constructs
AU600885B2 (en) * 1984-05-25 1990-08-30 Zymogenetics Inc. Stable DNA constructs
GB8415186D0 (en) * 1984-06-14 1984-07-18 Ciba Geigy Ag Polypeptides
EP0188555A4 (en) * 1984-07-09 1988-04-18 Integrated Genetics Inc YEAST CLONING VEHICLE.
JPS61502795A (ja) * 1984-07-09 1986-12-04 レモント，ジェフリ−・エフ 酵母クロ−ニング　ビ−クル
JPS61503002A (ja) * 1984-07-31 1986-12-25 アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ 酵母クロ−ニングベクタ−
JPS61103895A (ja) * 1984-10-26 1986-05-22 Green Cross Corp:The ＨＢｓＡｇの精製方法
CA1339912C (en) * 1984-12-06 1998-06-16 Jacques Oberto Transformed yeasts producing lysozyme, plasmids used for this transformation, and uses thereof
EP0194006B1 (en) * 1985-02-01 1992-04-29 Imperial Chemical Industries Plc Analogous interferon polypeptides, process for their preparation and pharmaceutical compositions containing them
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
JPS62151183A (ja) * 1985-09-18 1987-07-06 Green Cross Corp:The 酵母プロモ−タ−及び異種蛋白質の製造方法
DE3675724D1 (de) * 1985-09-18 1991-01-03 Green Cross Corp Hefe-promotor und verfahren zur herstellung von heterologen proteinen.
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
GB2188049B (en) * 1986-03-15 1990-09-05 Ciba Geigy Ag Insecticidal proteinaceous substance
EP0240224A3 (en) * 1986-03-31 1989-02-01 Interferon Sciences, Inc. An alpha interferon analogue
US4857467A (en) * 1986-07-23 1989-08-15 Phillips Petroleum Company Carbon and energy source markers for transformation of strains of the genes Pichia
ES2052602T3 (es) 1986-10-03 1994-07-16 Ciba Geigy Ag Nuevos peptidos afines a las linfocinas.
US5013652A (en) * 1986-10-14 1991-05-07 Genex Corporation Composite yeast vectors
ATE103930T1 (de) * 1988-03-07 1994-04-15 Ciba Geigy Ag Modifizierte proteine.
US5180667A (en) * 1988-03-07 1993-01-19 Ciba-Geigy Corporation Genes encoding eglin C mutants
DE68928124T2 (de) 1988-09-02 1997-10-16 Chiron Corp., Emeryville, Calif. Makrophagenabgeleiteter entzündungsmediator(mip-2)
JPH02145193A (ja) * 1988-11-19 1990-06-04 Lotte Confectionery Co Ltd 遺伝子の組換えによる酵母でのヒト・アルファ・インターフェロンの製造方法
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.
EP0752853B1 (en) 1993-03-10 2005-09-21 Smithkline Beecham Corporation Human brain phosphodiesterase
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
WO2004024885A2 (en) 2002-09-13 2004-03-25 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
DE102005030552B4 (de) * 2005-06-22 2009-05-28 Eucodis Bioscience Selektion von Phosphatase-Aktivität
CN102059495A (zh) * 2010-11-06 2011-05-18 中国长江航运集团宜昌船厂 一种船体框架胎模及加工方法
CA2819552C (en) 2010-12-09 2023-09-26 Institut Pasteur Mgmt-based method for obtaining high yield of recombinant protein expression
US8951752B2 (en) 2011-10-20 2015-02-10 University Of Iowa Research Foundation N-demethyase genes and uses thereof
BR112014013745B1 (pt) 2011-12-09 2022-06-14 Institut Pasteur Método de teste in vitro, kit de detecção e seu uso, método in vitro de diagnóstico, método de fabricação de kit, e teste de imunosseleção multiplex
EP2861740A1 (en) 2012-06-15 2015-04-22 University of Iowa Research Foundation Caffeine responsive promoters and regulatory genes
WO2022049409A1 (en) 2020-09-02 2022-03-10 Sia Terragen Express diagnosticum for sars-cov-2

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2458585A1 (fr) * 1979-06-07 1981-01-02 Pasteur Institut Procede de production de proteines par expression des genes correspondants dans des micro-organismes et vecteurs susceptibles d'etre mis en oeuvre dans de tels procedes
WO1981002425A1 (en) * 1980-02-25 1981-09-03 R Axel The use of eucaryotic promoter sequences in the production of proteinaceous materials
IL63270A0 (en) * 1980-08-05 1981-10-30 Univ Leland Stanford Junior Eukaryotic autonomously replicating segment
IL63035A (en) * 1980-09-09 1985-05-31 Univ California Dnas capable of replication and stable mitotic maintenance in a host eukaryote,their preparation and eukaryotic cells comprising them
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
US4615974A (en) * 1981-08-25 1986-10-07 Celltech Limited Yeast expression vectors
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド

Also Published As

Publication number Publication date
NO172548C (no) 1993-08-04
EP0100561B1 (en) 1989-05-31
AU566348B2 (en) 1987-10-15
DK361483D0 (da) 1983-08-08
FI832825L (fi) 1984-02-10
HU204095B (en) 1991-11-28
JPH0515379A (ja) 1993-01-26
AU1768283A (en) 1984-02-16
DD218118A5 (de) 1985-01-30
ES524816A0 (es) 1985-06-01
GB2125047A (en) 1984-02-29
CA1341381C (en) 2002-08-06
FI80720C (fi) 1990-07-10
CY1451A (en) 1989-03-10
GB2125047B (en) 1986-02-19
ATE43636T1 (de) 1989-06-15
JPH0653073B2 (ja) 1994-07-20
FI832825A0 (fi) 1983-08-05
DK361483A (da) 1984-02-10
NZ205178A (en) 1986-09-10
DK174905B1 (da) 2004-02-16
ES8607391A1 (es) 1986-05-16
PT77167B (en) 1986-03-20
GR78924B (no) 1984-10-02
EP0100561A1 (en) 1984-02-15
ES540880A0 (es) 1986-05-16
ES8505724A1 (es) 1985-06-01
ES540881A0 (es) 1986-05-16
JPS5948082A (ja) 1984-03-19
FI80720B (fi) 1990-03-30
DE3379960D1 (en) 1989-07-06
PH25617A (en) 1991-08-08
IE831860L (en) 1984-02-09
JPH0813277B2 (ja) 1996-02-14
ES8607026A1 (es) 1986-05-16
HK90688A (en) 1988-11-18
GB8319099D0 (en) 1983-08-17
IE55598B1 (en) 1990-11-21
PT77167A (en) 1983-09-01
NO172548B (no) 1993-04-26

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MK1K Patent expired

Free format text: EXPIRED IN AUGUST 2003