NO841797L - Radioaktive steroider, fremgangsmaate ved deres fremstilling og anvendelse derav for paavisning av mottagere for glucocorticoider og for bestemmelse av antall bindingspunkter - Google Patents

Radioaktive steroider, fremgangsmaate ved deres fremstilling og anvendelse derav for paavisning av mottagere for glucocorticoider og for bestemmelse av antall bindingspunkter

Info

Publication number: NO841797L
Authority: NO; Norway
Prior art keywords: determining; receivers; procedures; preparation; glucocorticoid
Prior art date: 1983-06-14

Application number

NO841797A

Other languages

English (en)

Other versions

NO162193B (no

NO162193C (no

Inventor

Alain Jouquey

Daniel Philibert

Martine Moguilewsky

Jean-Noel Veltz

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-14

Filing date

1984-05-04

Publication date

1984-12-17

1984-05-04 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1984-12-17 Publication of NO841797L publication Critical patent/NO841797L/no

1989-08-14 Publication of NO162193B publication Critical patent/NO162193B/no

1989-11-22 Publication of NO162193C publication Critical patent/NO162193C/no

Links

239000003862 glucocorticoid Substances 0.000 title abstract 3
230000002285 radioactive effect Effects 0.000 title abstract 2
150000003431 steroids Chemical class 0.000 title abstract 2
230000027455 binding Effects 0.000 title 1
238000009739 binding Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical compound [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
229940037128 systemic glucocorticoids Drugs 0.000 abstract 2
229910052722 tritium Inorganic materials 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Pathology (AREA)
Biochemistry (AREA)
General Physics & Mathematics (AREA)
Endocrinology (AREA)
Steroid Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Investigating Or Analysing Biological Materials (AREA)

NO841797A 1983-06-14 1984-05-04 Radioaktiv steroid, fremgangsmaate ved dets fremst., middel for paavisning in vitro av mottagere for glucocorticoiderog for bestemmelse av antall bindingspunkter for glucocorticoidene og anvendelse av steroidet for dette formaal NO162193C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8309811A FR2547587B1 (fr)	1983-06-14	1983-06-14	Steroides radioactifs, leur procede de preparation, leur application a la mise en evidence des recepteurs de glucocorticoides et au dosage du nombre de sites de fixation

Publications (3)

Publication Number	Publication Date
NO841797L true NO841797L (no)	1984-12-17
NO162193B NO162193B (no)	1989-08-14
NO162193C NO162193C (no)	1989-11-22

Family

ID=9289758

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO841797A NO162193C (no)	1983-06-14	1984-05-04	Radioaktiv steroid, fremgangsmaate ved dets fremst., middel for paavisning in vitro av mottagere for glucocorticoiderog for bestemmelse av antall bindingspunkter for glucocorticoidene og anvendelse av steroidet for dette formaal

Country Status (9)

Country	Link
US (2)	US4664850A (no)
EP (1)	EP0128839B1 (no)
JP (1)	JPS6034987A (no)
AT (1)	ATE43132T1 (no)
CA (2)	CA1222743A (no)
DE (1)	DE3478225D1 (no)
FI (1)	FI83784C (no)
FR (1)	FR2547587B1 (no)
NO (1)	NO162193C (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2592047B1 (fr) *	1985-12-19	1988-03-04	Roussel Uclaf	Complexes organometalliques de produits steroides ayant une affinite pour les recepteurs progestogene et gluco-corticoide et leur application au dosage des recepteurs hormonaux
US6372712B1 (en)	1998-05-22	2002-04-16	The Board Of Trustees Of The Leland Stanford Jr. University	Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
EP2671508B1 (en)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-informatics system
US9062126B2 (en)	2005-09-16	2015-06-23	Raptor Pharmaceuticals Inc.	Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1465484A (fr) *	1965-10-27	1967-01-13		Composés stéroïdes du type cétonique
FR2398076A1 (fr) *	1977-07-19	1979-02-16	Roussel Uclaf	Steroides marques au tritium, leur procede de preparation et leur application pour le dosage et la localisation des recepteurs tissulaires hormonaux des steroides
FR2398077A1 (fr) *	1977-07-19	1979-02-16	Roussel Uclaf	Steroides marques au tritium, leur procede de preparation et leur application pour le dosage et la localisation des recepteurs tissulaires hormonaux des steroides
FR2430952A1 (fr) *	1978-07-13	1980-02-08	Roussel Uclaf	Nouveaux derives acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicament

1983
- 1983-06-14 FR FR8309811A patent/FR2547587B1/fr not_active Expired
1984
- 1984-05-04 NO NO841797A patent/NO162193C/no unknown
- 1984-06-13 EP EP84401202A patent/EP0128839B1/fr not_active Expired
- 1984-06-13 DE DE8484401202T patent/DE3478225D1/de not_active Expired
- 1984-06-13 AT AT84401202T patent/ATE43132T1/de not_active IP Right Cessation
- 1984-06-13 CA CA000456494A patent/CA1222743A/fr not_active Expired
- 1984-06-13 FI FI842397A patent/FI83784C/fi not_active IP Right Cessation
- 1984-06-14 US US06/620,457 patent/US4664850A/en not_active Expired - Lifetime
- 1984-06-14 JP JP59120899A patent/JPS6034987A/ja active Granted
1985
- 1985-12-19 US US06/797,140 patent/US4865767A/en not_active Expired - Fee Related
1987
- 1987-02-17 CA CA000529937A patent/CA1242696A/fr not_active Expired

Also Published As

Publication number	Publication date
EP0128839B1 (fr)	1989-05-17
FI83784C (fi)	1991-08-26
JPH0460479B2 (no)	1992-09-28
FI83784B (fi)	1991-05-15
US4865767A (en)	1989-09-12
US4664850A (en)	1987-05-12
JPS6034987A (ja)	1985-02-22
FR2547587B1 (fr)	1985-10-25
ATE43132T1 (de)	1989-06-15
EP0128839A3 (en)	1985-09-18
FI842397A0 (fi)	1984-06-13
CA1222743A (fr)	1987-06-09
CA1242696A (fr)	1988-10-04
NO162193B (no)	1989-08-14
FI842397L (fi)	1984-12-15
DE3478225D1 (en)	1989-06-22
FR2547587A1 (fr)	1984-12-21
EP0128839A2 (fr)	1984-12-19
NO162193C (no)	1989-11-22

Publication	Publication Date	Title
HUT41047A (en)	1987-03-30	Process for preparing substituted steroids
ATE2221T1 (de)	1983-01-15	17-alpha-substituierte steroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung.
DE3560531D1 (en)	1987-10-08	Redox indicators
DK292579A (da)	1980-01-14	Fremgangsmaade til fremstilling af 3,20-dioxo-4,9-dien-21-hydroxylsteroider
DE3478225D1 (en)	1989-06-22	Labelled steroids, process for their preparation and intermediates, their use in the localization of the glucocorticoid receptors and in the dosage of the number of binding sites
ATE9469T1 (de)	1984-10-15	Reaktive derivate des 3-oxa-bicyclo(4.3.0)-non-1- en-9-ons, verfahren zu ihrer herstellung und deren verwendung.
JPS5399653A (en)	1978-08-31	Method of digesting sludge combined with aerobic*anaerobic sludge
NO841798L (no)	1984-12-17	Tritium-merkede radioaktive estradinderivater, fremgangsmaate ved deres fremstilling og anvendelse derav for radioimmunologisk undersoekelse og dosering av steroider i biologise vaesker
IE781753L (en)	1979-02-28	Steroid 3-oximes
GB2002385A (en)	1979-02-21	Steroid hemiesters and their use in radioimmunoassays
FI853560A0 (fi)	1985-09-17	Foerfarande foer framstaellning av pregnanderivat.
YU102083A (en)	1983-10-31	Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
PT70980B (fr)	1981-07-02	Procede de preparation de nouveaux steroides 7alpha-alkyles
PT74343B (fr)	1984-05-30	Nouveau procede de preparation de 17 alpha-hydroxy 17 beta- -hydroxyacetyl steroides
DK496283A (da)	1984-04-30	Fremgangsmaade til fremstilling af 7alfa-acylthio-1alfa,2alfa- methylen-3-oxo-17alfa-pregn-4-en-21,17-carbolactoner
DE3060093D1 (en)	1982-01-28	11-methylene steroids, process for their preparation and pharmaceutical compositions containing them
ES478210A1 (es)	1979-11-01	Un procedimiento de preparacion de derivados de la xantona.
JPS56110699A (en)	1981-09-01	11hydroxysteroid* its manufacture and progesterone containing it
KR830005262A (ko)	1983-08-03	안드로스탄 카보리오에이트의 제조방법
ES384344A1 (es)	1973-05-01	Un procedimiento de sintesis de esteroides c-17 alfa propa-dienil alquil sustituidos.
IE781820L (en)	1979-03-26	Pregnadiene compounds
FR2547588B1 (fr)	1985-10-25	Procede de preparation d'un 16-imino 17-aza steroide eventuellement tritie et intermediaire de ce procede
FR1241845A (fr)	1960-09-23	Procédé d'installation de captages des eaux souterraines