NO860710L - Merking av oligonukleotider. - Google Patents

Merking av oligonukleotider.

Info

Publication number
NO860710L
NO860710L NO860710A NO860710A NO860710L NO 860710 L NO860710 L NO 860710L NO 860710 A NO860710 A NO 860710A NO 860710 A NO860710 A NO 860710A NO 860710 L NO860710 L NO 860710L
Authority
NO
Norway
Prior art keywords
probe
oligonucleotide
nucleic acid
fragment
thalassemia
Prior art date
Application number
NO860710A
Other languages
English (en)
Norwegian (no)
Inventor
Nanibhushan Dattagupta
William Knowles
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/712,481 external-priority patent/US4808520A/en
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Publication of NO860710L publication Critical patent/NO860710L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO860710A 1985-03-15 1986-02-26 Merking av oligonukleotider. NO860710L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/712,481 US4808520A (en) 1985-03-15 1985-03-15 Labelling of oligonucleotides
US80887185A 1985-12-18 1985-12-18

Publications (1)

Publication Number Publication Date
NO860710L true NO860710L (no) 1986-09-16

Family

ID=27108843

Family Applications (1)

Application Number Title Priority Date Filing Date
NO860710A NO860710L (no) 1985-03-15 1986-02-26 Merking av oligonukleotider.

Country Status (10)

Country Link
EP (1) EP0194545B1 (de)
AU (1) AU592777B2 (de)
CA (1) CA1278755C (de)
DE (1) DE3667292D1 (de)
DK (1) DK119086A (de)
ES (1) ES8705920A1 (de)
FI (1) FI861039L (de)
IL (1) IL78123A (de)
NO (1) NO860710L (de)
NZ (1) NZ215453A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604099A (en) * 1986-03-13 1997-02-18 Hoffmann-La Roche Inc. Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
US4994368A (en) 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
US5273879A (en) * 1987-07-23 1993-12-28 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
CA1325761C (en) * 1987-12-25 1994-01-04 Takanori Oka Method of detecting an intended nucleic acid in a sample
US5047523A (en) * 1988-08-02 1991-09-10 Ortho Diagnostic Systems Inc. Nucleic acid probe for detection of neisseria gonorrhoea
US4879214A (en) * 1988-11-15 1989-11-07 E. I. Du Pont De Nemours And Company Differentiation of nucleic acid segments on the basis of nucleotide differences
US5324829A (en) * 1988-12-16 1994-06-28 Ortho Diagnostic Systems, Inc. High specific activity nucleic acid probes having target recognition and signal generating moieties
GR1000347B (el) * 1988-12-21 1992-06-25 Ortho Diagnostic Systems Inc Μεθοδος παραγωγης νουκλεοτιδικων ανιχνευτων χρησιμοποιωντας ενα συμπληρωμα γεφυρωσεως.
JPH03123500A (ja) * 1989-10-06 1991-05-27 Canon Inc 核酸の分別方法
US5612199A (en) * 1991-10-11 1997-03-18 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
ATE161586T1 (de) 1991-10-11 1998-01-15 Behringwerke Ag Verfahren zur herstellung eines polynukleotids zum gebrauch in ''single-primer'' amplifizierung und phosphorothioat-enthaltende oligonukleotide als primer in nukleinsäureamplifizierung
GB9201073D0 (en) * 1992-01-18 1992-03-11 Cytocell Ltd Chromosome hybridisation methods
JPH07509365A (ja) * 1992-07-31 1995-10-19 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング ポリヌクレオチド類の３’末端に特定配列を導入する方法
US6294323B1 (en) 1993-04-14 2001-09-25 Behringwerke Ag Self initiating single primer amplification of nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254525A (en) * 1983-04-13 1989-05-23 Christine L. Brakel Kit for terminally chemically labeling dna
DE3441369A1 (de) * 1984-11-13 1986-05-22 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von hydroxymethylen-alkoxyessigsaeureestern
US4734363A (en) * 1984-11-27 1988-03-29 Molecular Diagnostics, Inc. Large scale production of DNA probes
CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK171161B1 (da) * 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve

Also Published As

Publication number Publication date
AU5443186A (en) 1986-09-18
FI861039A7 (fi) 1986-09-16
IL78123A0 (en) 1986-07-31
FI861039L (fi) 1986-09-16
ES8705920A1 (es) 1987-05-16
NZ215453A (en) 1989-06-28
EP0194545A2 (de) 1986-09-17
EP0194545A3 (en) 1988-01-13
DK119086A (da) 1986-09-16
CA1278755C (en) 1991-01-08
ES553034A0 (es) 1987-05-16
AU592777B2 (en) 1990-01-25
IL78123A (en) 1990-02-09
FI861039A0 (fi) 1986-03-13
DK119086D0 (da) 1986-03-14
EP0194545B1 (de) 1989-12-06
DE3667292D1 (de) 1990-01-11

Similar Documents

Publication Publication Date Title
US5446137A (en) Oligonucleotides containing 4'-substituted nucleotides
Gebeyehu et al. Novel biotinylated nucleotide-analogs for labeling and colorimetric detection of DNA
NO860710L (no) Merking av oligonukleotider.
US8003769B2 (en) Dye-labeled ribonucleotide triphosphates
US5525494A (en) Amplification processes
US5948648A (en) Nucleotide compounds including a rigid linker
US6309836B1 (en) Compounds for protecting hydroxyls and methods for their use
CA1338597C (en) Reagents for the preparation of 5'-tagged oligonucleotides
US5430138A (en) Hydroxyl-protecting groups attached to cytidine nucleotide compounds which are orthogonally removable
CA2774344C (en) Terminal-phosphate-labeled nucleotides and methods of use
EP0360940B1 (de) Polynukleotid-Bestimmung mit selektierbaren Spaltstellen
JP2511005B2 (ja) インビトロにおけるオリゴヌクレオチド合成法並びにそれに用いる試薬
US4808520A (en) Labelling of oligonucleotides
US5547860A (en) Sulphocoumarin-containing nucleotides and their use in processes for detecting nucleic acids
WO2006074351A2 (en) Reversible nucleotide terminators and uses thereof
US6107039A (en) Assays using base protected table 1
JPH0730108B2 (ja) 修飾された核酸を製造するための修飾されたホスホルアミダイト法
CN116284185B (zh) 核苷酸类似物及其在测序中的应用
US5218102A (en) Nucleic acid probe containing a terminal carbamyl linking non-radioactive labeling and preparating processes
JPH01500353A (ja) ２′‐デオキシアデノシン誘導体を含む核酸検出用プローブ
EP0471338B1 (de) Phenytoinderivate
EP1546399B1 (de) Nukleosidpolyphosphate mit blockiertem terminalem phosphat
CN112888699A (zh) 测序用核苷酸的制备方法
Geiger et al. A new approach for the efficient synthesis of oligodeoxyribonucleotides containing the mutagenic DNA modification 7, 8-dihydro-8-oxo-2′-deoxyguanosine at predefined positions
Rashtchian et al. Labeling and detection of nucleic acids