NO862177D0 - Monoklonale antistoffer til cyklosporinger. - Google Patents

Monoklonale antistoffer til cyklosporinger.

Info

Publication number
NO862177D0
NO862177D0 NO1986862177A NO862177A NO862177D0 NO 862177 D0 NO862177 D0 NO 862177D0 NO 1986862177 A NO1986862177 A NO 1986862177A NO 862177 A NO862177 A NO 862177A NO 862177 D0 NO862177 D0 NO 862177D0
Authority
NO
Norway
Prior art keywords
monoclonal antibodies
cyclosporine
succinimidooxysuccinyl
cyclosporins
cycle tracks
Prior art date
Application number
NO1986862177A
Other languages
English (en)
Other versions
NO862177L (no
NO173557C (no
NO173557B (no
Inventor
Joachim Rosenthaler
Roland Wenger
Phillip E Ball
Max H Schreier
Valerie Quesniaux
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848425040A external-priority patent/GB8425040D0/en
Priority claimed from GB858515673A external-priority patent/GB8515673D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO862177D0 publication Critical patent/NO862177D0/no
Publication of NO862177L publication Critical patent/NO862177L/no
Publication of NO173557B publication Critical patent/NO173557B/no
Publication of NO173557C publication Critical patent/NO173557C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
NO862177A 1984-10-04 1986-06-02 Monoklonalt antistoff, immunogent konjugat, cyklosporin, fremgangsmaate for fremstilling av det monoklonale antistoff samt immunotestsett NO173557C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB848425040A GB8425040D0 (en) 1984-10-04 1984-10-04 Organic compounds
GB858515673A GB8515673D0 (en) 1985-06-20 1985-06-20 Organic compounds
PCT/EP1985/000501 WO1986002080A1 (en) 1984-10-04 1985-09-27 Monoclonal antibodies to cyclosporings

Publications (4)

Publication Number Publication Date
NO862177D0 true NO862177D0 (no) 1986-06-02
NO862177L NO862177L (no) 1986-08-04
NO173557B NO173557B (no) 1993-09-20
NO173557C NO173557C (no) 1993-12-29

Family

ID=26288301

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862177A NO173557C (no) 1984-10-04 1986-06-02 Monoklonalt antistoff, immunogent konjugat, cyklosporin, fremgangsmaate for fremstilling av det monoklonale antistoff samt immunotestsett

Country Status (15)

Country Link
EP (4) EP0314861A1 (no)
JP (1) JPH074269B2 (no)
KR (1) KR910002691B1 (no)
AT (1) ATE92501T1 (no)
AU (4) AU589917B2 (no)
CA (1) CA1309671C (no)
CY (2) CY1915A (no)
DE (2) DE3587342T2 (no)
DK (1) DK172037B1 (no)
ES (1) ES8702949A1 (no)
FI (1) FI93965C (no)
HK (2) HK78696A (no)
NO (1) NO173557C (no)
NZ (1) NZ213680A (no)
WO (1) WO1986002080A1 (no)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
US5239057A (en) * 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
EP0283801A3 (en) * 1987-03-27 1990-05-30 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US5698448A (en) * 1988-12-02 1997-12-16 Soldin; Steven J. Immunosuppressive drug binding proteins and use
CA2004626A1 (en) * 1988-12-05 1990-06-05 Bernard F. Erlanger Derivatives of cyclosporine a, antibodies directed thereto and uses thereof
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
EP0473961B1 (en) * 1990-08-15 1996-01-03 Abbott Laboratories Immunoassay reagents and method for determining cyclosporine
CA2048302A1 (en) * 1990-08-15 1992-02-16 Victoria P. Meucci Solubilization reagent for biological test samples
DE69121844T2 (de) 1990-11-20 1997-01-23 Behringwerke Ag Immunotest für Cyclosporin
USRE40596E1 (en) * 1993-04-08 2008-12-02 Novartis Ag Rapamycin assay
GB9307491D0 (en) 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
US6270957B1 (en) 1997-08-26 2001-08-07 Wisconsin Alumni Research Foundation Non-Imuunosuppressive cyclosporins and their use in the prevention and treatment of HIV infection
WO1999010373A1 (en) * 1997-08-26 1999-03-04 Wisconsin Alumni Research Foundation Non-immunosuppressive cyclosporins and their use in the prevention and treatment of hiv infection
US20030220234A1 (en) 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
US5990274A (en) * 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
PT1091975E (pt) 1998-07-01 2006-05-31 Debiopharm Sa Nova ciclosporina com um perfil de actividade melhorado
US6686454B1 (en) 1998-10-09 2004-02-03 Isotechnika, Inc. Antibodies to specific regions of cyclosporine related compounds
AU763822B2 (en) * 1998-10-09 2003-07-31 Isotechnika, Inc. Methods for the production of antibodies to specific regions of cyclosporine and cyclosporine metabolites
RU2207870C2 (ru) * 2000-11-10 2003-07-10 Панацея Биотек Лимитед Фармацевтическая композиция, включающая циклоспорин в качестве активного ингредиента
US7141648B2 (en) 2001-10-19 2006-11-28 Isotechnika Inc. Synthesis of cyclosporin analogs
US8288111B2 (en) 2007-05-24 2012-10-16 Abbott Laboratories Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites
TW200932240A (en) 2007-10-25 2009-08-01 Astellas Pharma Inc Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production
EP3415151A1 (en) * 2008-05-23 2018-12-19 The University of British Columbia Modified drugs for use in liposomal nanoparticles
WO2010088573A1 (en) 2009-01-30 2010-08-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
WO2012145426A1 (en) 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Methods to treat cancer using cyclosporine and cyclosporine derivatives
WO2014085623A1 (en) 2012-11-28 2014-06-05 Enanta Pharmaceuticals, Inc. Novel [n-me-4-hydroxyleucine]-9-cyclosporin analogues
WO2015031381A1 (en) 2013-08-26 2015-03-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis c
US9669095B2 (en) 2014-11-03 2017-06-06 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C infection
US10533016B2 (en) 2015-01-09 2020-01-14 Revolution Medicines, Inc. Compounds that participate in cooperative binding and uses thereof
WO2017059207A1 (en) 2015-10-01 2017-04-06 Warp Drive Bio, Inc. Methods and reagents for analyzing protein-protein interfaces
CA3020594A1 (en) 2016-04-12 2017-10-19 Warp Drive Bio, Inc. Compositions and methods for the production of compounds
JP2020501519A (ja) 2016-10-28 2020-01-23 ギンゴー バイオワークス， インコーポレイテッド 化合物の生産のための組成物および方法
CN120699039A (zh) 2019-11-04 2025-09-26 锐新医药公司 Ras抑制剂
MX2022005359A (es) 2019-11-04 2022-06-02 Revolution Medicines Inc Inhibidores de ras.
WO2021091956A1 (en) 2019-11-04 2021-05-14 Revolution Medicines, Inc. Ras inhibitors
MX2023003060A (es) 2020-09-15 2023-04-05 Revolution Medicines Inc Derivados indolicos como inhibidores de ras en el tratamiento del cancer.
AU2022268962A1 (en) 2021-05-05 2023-12-14 Revolution Medicines, Inc. Ras inhibitors for the treatment of cancer
AR127308A1 (es) 2021-10-08 2024-01-10 Revolution Medicines Inc Inhibidores ras

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB211526A (en) 1922-09-22 1924-02-22 John Fletcher Holliday Improvements in and relating to chain grate stokers
CH614931A5 (no) 1975-11-04 1979-12-28 Sandoz Ag
US4210581A (en) 1975-11-04 1980-07-01 Sandoz Ltd. Organic compounds
DE2819094A1 (de) 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
EP0034567B1 (en) * 1980-02-14 1984-11-07 Sandoz Ag A method for the total synthesis of cyclosporins and novel cyclosporins
IL62965A0 (en) 1980-07-17 1981-07-31 Scripps Miles Lab Inc Monoclonal antibodies to drugs and theri production
DE3260468D1 (en) * 1981-01-09 1984-09-06 Sandoz Ag Novel cyclosporins
CH667274A5 (de) 1984-03-23 1988-09-30 Sandoz Ag Cyclosporine, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
GB8407618D0 (en) 1984-03-23 1984-05-02 Sandoz Ltd Organic compounds

Also Published As

Publication number Publication date
DE3587505T2 (de) 1994-01-05
EP0290762B1 (en) 1993-05-12
EP0290762A1 (en) 1988-11-17
KR870700637A (ko) 1987-12-30
WO1986002080A1 (en) 1986-04-10
NO862177L (no) 1986-08-04
AU4967185A (en) 1986-04-17
AU3914289A (en) 1989-10-26
FI862370A0 (fi) 1986-06-03
FI93965C (fi) 1995-06-26
CA1309671C (en) 1992-11-03
DK172037B1 (da) 1997-09-22
KR910002691B1 (ko) 1991-05-03
HK78696A (en) 1996-05-10
NZ213680A (en) 1990-05-28
CY1915A (en) 1985-09-27
AU3914189A (en) 1989-11-16
NO173557C (no) 1993-12-29
JPH074269B2 (ja) 1995-01-25
FI93965B (fi) 1995-03-15
EP0198026B1 (en) 1993-08-04
AU3914389A (en) 1989-11-16
ATE92501T1 (de) 1993-08-15
DK261386A (da) 1986-06-03
JPS62500383A (ja) 1987-02-19
DE3587342T2 (de) 1993-12-02
EP0198026A1 (en) 1986-10-22
FI862370A7 (fi) 1986-06-03
HK124696A (en) 1996-07-19
CY1927A (en) 1997-05-16
NO173557B (no) 1993-09-20
EP0314861A1 (en) 1989-05-10
EP0314862A1 (en) 1989-05-10
DE3587505D1 (de) 1993-09-09
DE3587342D1 (en) 1993-06-17
DK261386D0 (da) 1986-06-03
ES547495A0 (es) 1987-01-16
AU589917B2 (en) 1989-10-26
ES8702949A1 (es) 1987-01-16

Similar Documents

Publication Publication Date Title
NO862177D0 (no) Monoklonale antistoffer til cyklosporinger.
DE69133095D1 (de) Cyclosporin-Immunoassay
MY104946A (en) Antigen antibody conjugate.
IL132380A0 (en) Compositions comprising conjugates of stable active human ob protein with antibody fc chain and methods
AU3066489A (en) Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore
CA2267072A1 (en) Reconstituted human anti-hm1.24 antibody
IL86809A (en) Second generation monoclonal antibodies with binding specificity to tag-72, method for detecting human carcinomas utilizing the same, and pharmaceutical compositions containing the same
AU1520895A (en) Purified primate ctla-8 antigens and related reagents
CA2239167A1 (en) Aldolase catalytic antibody
ES2123677T3 (es) Ligadores de maleinimida trifuncionales homobidentados y su uso en conjugados inmunologicamente activos.
AU3192889A (en) T cell activation markers
DE68918295D1 (de) Elektronenkollektor für eine Elektronenröhre.
AU576088B2 (en) Histamine derivatives, immunogen conjugates and antibodies raised thereto
EP0734451A4 (en) ENTEROTOXINE FROM -I (SHIGELLA FLEXNERI)
AU7796291A (en) High affinity antibodies to small peptides
IL77862A (en) Enzymatic immunoassay to determine the amount of antibodies to htlv-iii and test kit
ES2173879T3 (es) Procedimiento para la preparacion de conjugados a base de un participe especifico en la fijacion y de una proteina que contiene hidratos de carbono
NO982227L (no) Urogenitalcarcinom-TPL komplekspeptider og antistoffer derav
IL141858A0 (en) Diagnostic method for detecting disturbances of the pancreas
AU5771798A (en) Antigen
EP0674907A3 (en) Antibody-carrier protein conjugates, for use in active immunotherapy.
ATE89828T1 (de) Octapeptide als hemmer myristoylierender enzyme.
ZA857684B (en) Monoclonal antibodies to cyclosporins
NO904742D0 (no) Rekobinant immunogen (antistoff mot membranmolekyler paa antigenpresenterende celler koplet med immunogene peptider).

Legal Events

Date Code Title Description
MK1K Patent expired