NO883828L - Fremgangsmaate for fremstilling av opploeselige preparater for behandling av diabetes mellitus eller hypoglycemi. - Google Patents

Fremgangsmaate for fremstilling av opploeselige preparater for behandling av diabetes mellitus eller hypoglycemi.

Info

Publication number
NO883828L
NO883828L NO88883828A NO883828A NO883828L NO 883828 L NO883828 L NO 883828L NO 88883828 A NO88883828 A NO 88883828A NO 883828 A NO883828 A NO 883828A NO 883828 L NO883828 L NO 883828L
Authority
NO
Norway
Prior art keywords
dap
hypoglycemia
preparation
diabetes mellitus
procedure
Prior art date
Application number
NO88883828A
Other languages
English (en)
Other versions
NO883828D0 (no
Inventor
Garth James Smith Cooper
Original Assignee
Amylin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Corp filed Critical Amylin Corp
Publication of NO883828D0 publication Critical patent/NO883828D0/no
Publication of NO883828L publication Critical patent/NO883828L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/225—Calcitonin gene related peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Socks And Pantyhose (AREA)

Abstract

En fremgangsmåte for fremstilling av oppløselige preparater for behandling av diabetes mellitus eller hypoglycemi, hvor en aktiv bestanddel valgt fra DAP, DAP-NH-, CGRP, funksjon- elle peptidfragmenter derav og konservative varianter av DAP eller DAP-NH_ eller CGRP, eller fragmenter derav, bringes i form av en oppløsning egnet for parenteral tilførsel, særlig parenteral tilførsel sammen med insulin. Forskjellige utførelsesformer for å oppnå preparatformer er beskrevet, for eksempel behandling med maursyre, guanidinium-hydroklorid-buffer, salter og andre tilsetnings- midler, samt behandling med ultralyd.
NO88883828A 1987-08-26 1988-08-26 Fremgangsmaate for fremstilling av opploeselige preparater for behandling av diabetes mellitus eller hypoglycemi. NO883828L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878720115A GB8720115D0 (en) 1987-08-26 1987-08-26 Treatment of diabetes mellitus

Publications (2)

Publication Number Publication Date
NO883828D0 NO883828D0 (no) 1988-08-26
NO883828L true NO883828L (no) 1989-02-27

Family

ID=10622830

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88883828A NO883828L (no) 1987-08-26 1988-08-26 Fremgangsmaate for fremstilling av opploeselige preparater for behandling av diabetes mellitus eller hypoglycemi.

Country Status (15)

Country Link
US (2) US5124314A (no)
EP (2) EP0787741A1 (no)
JP (1) JP2828250B2 (no)
AT (1) ATE155688T1 (no)
AU (1) AU634954B2 (no)
CA (1) CA1341060C (no)
DE (1) DE3855970T2 (no)
DK (1) DK473888A (no)
ES (1) ES2106721T3 (no)
FI (1) FI883936L (no)
GB (1) GB8720115D0 (no)
GR (1) GR3024705T3 (no)
HK (1) HK1000934A1 (no)
NO (1) NO883828L (no)
SG (1) SG93776A1 (no)

Families Citing this family (92)

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US5266561A (en) * 1988-01-11 1993-11-30 Amylin Pharmaceuticals, Inc. Treatment of type 2 diabetes mellitus
GB8915712D0 (en) * 1989-07-08 1989-08-31 Macintyre Iain Medical treatment
US5405831A (en) * 1989-07-08 1995-04-11 Amylin Pharmaceuticals, Inc. Treatment of bone disorders
JP2533726Y2 (ja) * 1990-07-23 1997-04-23 船井電機株式会社 記録再生機器
US5260275A (en) * 1990-08-14 1993-11-09 Amylin Pharmaceuticals, Inc. Hypoglycemics
US5321008A (en) * 1991-01-10 1994-06-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
US5527771A (en) * 1991-01-10 1996-06-18 Amylin Pharmaceuticals, Inc. Methods and Compositions for treatment of diabetes mellitus, hypoglycemia & other conditions
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WO1992015317A1 (en) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Synthetic preparation of amylin and amylin analogues
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US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
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US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
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WO1993019774A1 (en) * 1992-04-03 1993-10-14 Amylin Pharmaceuticals, Inc. Amylin and possibly insulin containing composition for the treatment of anorexia and related states
JPH07506114A (ja) * 1992-08-06 1995-07-06 ファイザー・インコーポレーテッド アミリン突然変異タンパク質
US5376638A (en) * 1992-09-01 1994-12-27 Amylin Pharmaceuticals, Inc. Methods for treating renin-related disorders with amylin antagonists
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US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
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KR950007873A (ko) * 1993-09-20 1995-04-15 후꾸하라 요시하루 생리 활성 물질 지속 방출형의 의약 제제
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US6110707A (en) * 1996-01-19 2000-08-29 Board Of Regents, The University Of Texas System Recombinant expression of proteins from secretory cell lines
CA2246431A1 (en) * 1996-01-19 1997-07-24 Board Of Regents, The University Of Texas System Recombinant expression of proteins from secretory cell lines
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US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
DE19725619A1 (de) * 1997-06-17 1998-12-24 Fraunhofer Ges Forschung Peptide als Agonisten und/oder Inhibitoren der Amyloidbildung und Zytotoxizität sowie der Verwendung bei Alzheimer'schen Krankheit, beim Typ II Diabetes mellitus und bei spongiformen Encephalopathien
US6821954B2 (en) 1997-09-18 2004-11-23 Auckland Uniservices Limited Compounds and uses thereof in treating bone disorders
EP1051141A4 (en) * 1998-01-09 2001-05-23 Amylin Pharmaceuticals Inc INSULIN-CONTAINING AMYLINE AGONIST PHARMACEUTICAL COMPOSITIONS
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US6087334A (en) * 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides
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EP3562500B1 (fr) 2016-12-27 2023-07-19 Adocia Compositions sous forme de solution aqueuse injectable comprenant de l'amyline, un agoniste au récepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
PL3658115T4 (pl) 2017-07-27 2022-08-08 Adocia Kompozycje w postaci wodnego roztworu do wstrzykiwań zawierające co najmniej insulinę ludzką a21g i co najmniej jeden supresor glukagonu o działaniu prandialnym
FR3082426A1 (fr) 2018-06-14 2019-12-20 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant au moins de l'insuline humaine a21g et un suppresseur de glucagon a action prandiale
FR3083089A1 (fr) 2018-06-29 2020-01-03 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
KR20240171194A (ko) 2017-12-07 2024-12-06 아도시아 아밀린, 아밀린 작용제 수용체 또는 아밀린 유사체 및 코-폴리아미노산을 포함하는 주사용 수용액 형태의 조성물
EP3740195A1 (fr) 2017-12-07 2020-11-25 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
BR112020011479A2 (pt) 2017-12-07 2020-11-17 Adocia composições na forma de uma solução aquosa injetável caracterizada pelo fato de que compreende amilina, um agonista do receptor de amilina ou um análogo de amilina e um co-poliaminoácido
FR3083085B1 (fr) 2018-06-29 2020-10-02 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
MX2020005914A (es) 2017-12-07 2020-10-19 Adocia Solución inyectable con un ph 7 de 7 que incluye al menos una insulina basal con un pi de entre 5.8 y 8.5 y un copoliaminoácido con cargas de carboxilato y radicales hidrofóbicos.
JP7637965B2 (ja) 2017-12-07 2025-03-03 アドシア ５．８～８．５のｐＩを有する少なくとも１つの基礎インスリンならびにカルボキシレート電荷および疎水性ラジカルを有するコポリアミノ酸を含むｐＨ７の注射溶液
FR3083086A1 (fr) 2018-06-29 2020-01-03 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
WO2019115411A1 (fr) 2017-12-07 2019-06-20 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
FR3084586B1 (fr) 2018-08-03 2020-11-06 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un compose amphiphile porteur de radicaux hydrophobes
EP3915571A1 (en) 2020-05-29 2021-12-01 Adocia Pharmaceutical composition in the form of an injectable aqueous solution including at least a rapid acting insulin analog and a glucagon suppressor with prandial action
EP3915572A1 (en) 2020-05-29 2021-12-01 Adocia Pharmaceutical composition in the form of an injectable aqueous solution including at least a rapid acting insulin analog and a glucagon suppressor with prandial action

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EP0270376B1 (en) * 1986-12-04 1992-09-30 Asahi Kasei Kogyo Kabushiki Kaisha Calcitonin gene-related peptide derivatives
GB8709871D0 (en) 1987-04-27 1987-06-03 Turner R C Peptides

Also Published As

Publication number Publication date
SG93776A1 (en) 2003-01-21
NO883828D0 (no) 1988-08-26
US5124314A (en) 1992-06-23
ES2106721T3 (es) 1997-11-16
JPH0196137A (ja) 1989-04-14
FI883936A0 (fi) 1988-08-25
DK473888D0 (da) 1988-08-25
AU2157588A (en) 1989-07-20
EP0309100B1 (en) 1997-07-23
JP2828250B2 (ja) 1998-11-25
EP0309100A3 (en) 1991-04-03
DE3855970T2 (de) 1998-01-29
FI883936A7 (fi) 1989-02-27
GB8720115D0 (en) 1987-09-30
US5641744A (en) 1997-06-24
DE3855970D1 (de) 1997-09-04
EP0787741A1 (en) 1997-08-06
EP0309100A2 (en) 1989-03-29
GR3024705T3 (en) 1997-12-31
DK473888A (da) 1989-04-05
AU634954B2 (en) 1993-03-11
CA1341060C (en) 2000-07-25
FI883936L (fi) 1989-02-27
ATE155688T1 (de) 1997-08-15
HK1000934A1 (en) 1998-05-08

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