NO891243L - Fremgangsmaate ved fremstilling av en n-beskyttet alfa-l-aspartyl-l-fenylalaninmethylester. - Google Patents

Fremgangsmaate ved fremstilling av en n-beskyttet alfa-l-aspartyl-l-fenylalaninmethylester.

Info

Publication number: NO891243L
Authority: NO; Norway
Prior art keywords: protected; methyl ester; phenylalanine methyl; aspartyl; alfa
Prior art date: 1988-03-22

Application number

NO89891243A

Other languages

English (en)

Norwegian (no)

Other versions

NO891243D0 (no

Inventor

Toshio Katoh

Chojiro Higuchi

Takeshi Oura

Masanobu Ajioka

Akihiro Yamaguchi

Original Assignee

Mitsui Toatsu Chemicals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-22

Filing date

1989-03-21

Publication date

1989-09-25

1988-03-22 Priority claimed from JP63065920A external-priority patent/JP2647420B2/ja

1988-05-09 Priority claimed from JP11040388A external-priority patent/JP2688210B2/ja

1988-05-09 Priority claimed from JP63110417A external-priority patent/JP2698372B2/ja

1988-06-13 Priority claimed from JP63143674A external-priority patent/JP2647439B2/ja

1988-07-01 Priority claimed from JP16259388A external-priority patent/JP2598467B2/ja

1988-07-07 Priority claimed from JP16978388A external-priority patent/JP2688214B2/ja

1988-07-07 Priority claimed from JP16978288A external-priority patent/JP2688213B2/ja

1988-07-21 Priority claimed from JP63180358A external-priority patent/JP2598470B2/ja

1989-03-21 Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals

1989-03-21 Publication of NO891243D0 publication Critical patent/NO891243D0/no

1989-09-25 Publication of NO891243L publication Critical patent/NO891243L/no

Links

WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
238000004519 manufacturing process Methods 0.000 abstract 3
GWKOSRIHVSBBIA-REOHCLBHSA-N (3s)-3-aminooxolane-2,5-dione Chemical compound N[C@H]1CC(=O)OC1=O GWKOSRIHVSBBIA-REOHCLBHSA-N 0.000 abstract 2
XYXYXSKSTZAEJW-VIFPVBQESA-N (2s)-2-(phenylmethoxycarbonylamino)butanedioic acid Chemical compound OC(=O)C[C@@H](C(O)=O)NC(=O)OCC1=CC=CC=C1 XYXYXSKSTZAEJW-VIFPVBQESA-N 0.000 abstract 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 abstract 1
229960005261 aspartic acid Drugs 0.000 abstract 1
235000003704 aspartic acid Nutrition 0.000 abstract 1
OZPYEGOBGWQOSZ-VIFPVBQESA-N benzyl n-[(3s)-2,5-dioxooxolan-3-yl]carbamate Chemical compound C=1C=CC=CC=1COC(=O)N[C@H]1CC(=O)OC1=O OZPYEGOBGWQOSZ-VIFPVBQESA-N 0.000 abstract 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
VSDUZFOSJDMAFZ-VIFPVBQESA-N methyl L-phenylalaninate Chemical compound COC(=O)[C@@H](N)CC1=CC=CC=C1 VSDUZFOSJDMAFZ-VIFPVBQESA-N 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Seasonings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO89891243A 1988-03-22 1989-03-21 Fremgangsmaate ved fremstilling av en n-beskyttet alfa-l-aspartyl-l-fenylalaninmethylester. NO891243L (no)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
JP63065920A JP2647420B2 (ja)	1988-03-22	1988-03-22	Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの製造方法
JP11040388A JP2688210B2 (ja)	1988-05-09	1988-05-09	Ｎ−保護アスパラギン酸無水物の製造法
JP63110417A JP2698372B2 (ja)	1988-05-09	1988-05-09	Ｎ−保護アスパラギン酸無水物の製造方法
JP63143674A JP2647439B2 (ja)	1988-06-13	1988-06-13	Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの製造方法
JP16259388A JP2598467B2 (ja)	1988-07-01	1988-07-01	Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの製造方法
JP16978388A JP2688214B2 (ja)	1988-07-07	1988-07-07	Ｎ−カルボベンゾキシ−ｌ−アスパラギン酸無水物の製造方法
JP16978288A JP2688213B2 (ja)	1988-07-07	1988-07-07	Ｎ−カルボベンゾキシ−ｌ−アスパラギン酸無水物の製造法
JP63180358A JP2598470B2 (ja)	1988-07-21	1988-07-21	Ｎ−ベンジルオキシカルボニル―αーＬ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの製造方法

Publications (2)

Publication Number	Publication Date
NO891243D0 NO891243D0 (no)	1989-03-21
NO891243L true NO891243L (no)	1989-09-25

Family

ID=27572581

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO89891243A NO891243L (no)	1988-03-22	1989-03-21	Fremgangsmaate ved fremstilling av en n-beskyttet alfa-l-aspartyl-l-fenylalaninmethylester.

Country Status (9)

Country	Link
EP (1)	EP0334236B1 (fr)
KR (1)	KR910006287B1 (fr)
AT (1)	ATE110740T1 (fr)
AU (1)	AU605968B2 (fr)
BR (1)	BR8901324A (fr)
CA (1)	CA1339658C (fr)
DE (1)	DE68917762T2 (fr)
DK (1)	DK141289A (fr)
NO (1)	NO891243L (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2697844B1 (fr) *	1992-11-12	1995-01-27	Claude Nofre	Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
KR100255843B1 (ko) *	1997-08-07	2000-05-01	허진호	회전형 씨디피

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4173562A (en) *	1976-12-27	1979-11-06	Monsanto Company	Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester

1989
- 1989-03-16 DE DE68917762T patent/DE68917762T2/de not_active Expired - Fee Related
- 1989-03-16 AT AT89104832T patent/ATE110740T1/de not_active IP Right Cessation
- 1989-03-16 EP EP89104832A patent/EP0334236B1/fr not_active Expired - Lifetime
- 1989-03-16 CA CA000593914A patent/CA1339658C/fr not_active Expired - Fee Related
- 1989-03-21 NO NO89891243A patent/NO891243L/no unknown
- 1989-03-21 BR BR898901324A patent/BR8901324A/pt not_active Application Discontinuation
- 1989-03-22 DK DK141289A patent/DK141289A/da not_active Application Discontinuation
- 1989-03-22 AU AU31620/89A patent/AU605968B2/en not_active Ceased
- 1989-03-22 KR KR1019890003589A patent/KR910006287B1/ko not_active Expired

Also Published As

Publication number	Publication date
EP0334236A2 (fr)	1989-09-27
AU605968B2 (en)	1991-01-24
DK141289A (da)	1989-09-23
EP0334236A3 (fr)	1991-03-20
DK141289D0 (da)	1989-03-22
ATE110740T1 (de)	1994-09-15
KR910006287B1 (ko)	1991-08-19
BR8901324A (pt)	1989-11-07
NO891243D0 (no)	1989-03-21
EP0334236B1 (fr)	1994-08-31
CA1339658C (fr)	1998-02-03
KR890014576A (ko)	1989-10-24
DE68917762D1 (de)	1994-10-06
AU3162089A (en)	1989-09-28
DE68917762T2 (de)	1995-04-13

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