NO894155L - Fremgangsmaate ved fremstilling av penem'er. - Google Patents

Fremgangsmaate ved fremstilling av penem'er.

Info

Publication number: NO894155L
Authority: NO; Norway
Prior art keywords: penems; procedure; manufacturing; azetidon; triphenylmethylthio
Prior art date: 1988-10-19

Application number

NO89894155A

Other languages

English (en)

Other versions

NO174054C (no

NO174054B (no

NO894155D0 (no

Inventor

Brian Thomas O'neill

Douglas Phillips

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-19

Filing date

1989-10-18

Publication date

1990-04-20

1988-10-19 Priority claimed from US07/260,141 external-priority patent/US4895940A/en

1989-10-18 Application filed by Pfizer filed Critical Pfizer

1989-10-18 Publication of NO894155D0 publication Critical patent/NO894155D0/no

1990-04-20 Publication of NO894155L publication Critical patent/NO894155L/no

1993-11-29 Publication of NO174054B publication Critical patent/NO174054B/no

1994-03-09 Publication of NO174054C publication Critical patent/NO174054C/no

Links

238000000034 method Methods 0.000 title abstract 2
150000002961 penems Chemical class 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000002168 ethanoic acid esters Chemical class 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pens And Brushes (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Electric Double-Layer Capacitors Or The Like (AREA)
Glass Compositions (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

NO894155A 1988-10-19 1989-10-18 Fremgangsmåte ved fremstilling av mellomprodukter for penem'er NO174054C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/260,141 US4895940A (en)	1988-10-19	1988-10-19	Process for the preparation of penems
US07/378,743 US4992543A (en)	1988-10-19	1989-07-11	Penem derivatives

Publications (4)

Publication Number	Publication Date
NO894155D0 NO894155D0 (no)	1989-10-18
NO894155L true NO894155L (no)	1990-04-20
NO174054B NO174054B (no)	1993-11-29
NO174054C NO174054C (no)	1994-03-09

Family

ID=26947752

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO894155A NO174054C (no)	1988-10-19	1989-10-18	Fremgangsmåte ved fremstilling av mellomprodukter for penem'er

Country Status (23)

Country	Link
US (2)	US4992543A (no)
EP (1)	EP0365223B1 (no)
JP (1)	JPH06104672B2 (no)
KR (1)	KR920001780B1 (no)
CN (1)	CN1023015C (no)
AT (1)	ATE142212T1 (no)
AU (1)	AU606820B2 (no)
CA (1)	CA1339845C (no)
DE (1)	DE68927085T2 (no)
DK (1)	DK174484B1 (no)
ES (1)	ES2091199T3 (no)
FI (1)	FI94252C (no)
GR (1)	GR3021351T3 (no)
HU (1)	HU206216B (no)
IE (1)	IE75358B1 (no)
IL (1)	IL91961A (no)
MY (1)	MY104239A (no)
NO (1)	NO174054C (no)
NZ (1)	NZ231055A (no)
PH (1)	PH26051A (no)
PL (1)	PL163376B1 (no)
PT (1)	PT92022B (no)
YU (1)	YU47073B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5191075A (en) *	1988-10-19	1993-03-02	Pfizer Inc	Process for the preparation of penems
DK0382418T3 (da) *	1989-02-09	1991-10-23	Pfizer	Fremgangsmåde til fremstilling af optisk aktive 3-thiolanyl-sulfonatestere
DE69225821T2 (de) *	1991-03-13	1998-11-05	Otsuka Kagaku Kk	Penamderivate und Verfahren zu deren Herstellung
US20040198066A1 (en) *	2003-03-21	2004-10-07	Applied Materials, Inc.	Using supercritical fluids and/or dense fluids in semiconductor applications
CN109796434B (zh) *	2019-01-25	2020-10-30	凯莱英生命科学技术(天津)有限公司	硫培南侧链的合成方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4272437A (en) *	1978-12-18	1981-06-09	Bristol-Myers Company	Antibacterial agents, and 4-thio azetidinone intermediates
US4314942A (en) *	1979-01-10	1982-02-09	Schering Corporation	Deprotection of allylic esters, carbonates and carbamates catalyzed by palladium compounds
US4443463A (en) *	1979-11-05	1984-04-17	Schering Corporation	(5R,6S,8R)-6-(1-Hydroxyethyl)-2-(hydroxyalkylthio)-penem-3-carboxylates
US4482565A (en) *	1980-02-22	1984-11-13	Farmitalia Carlo Erba S.P.A.	β-Lactam-containing antibacterial agents and β-lactamase inhibitors
US4443373A (en) *	1982-03-30	1984-04-17	Schering Corporation	Process for the production of antibiotic penems
NO831160L (no) *	1982-04-08	1983-10-10	Erba Farmitalia	Fremstilling av substituerte penem-derivater
US4530793A (en) *	1982-11-29	1985-07-23	Schering Corporation	Processes for the production of penems
DE3382761T2 (de) *	1982-11-29	1995-03-09	Schering Corp	Verfahren zur Herstellung von Penem-Verbindungen.
EP0320497A1 (en) *	1983-01-25	1989-06-14	Merck & Co. Inc.	Substituted 2-thioxopenams, intermediates therefrom and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems
EP0115308A3 (en) *	1983-01-25	1984-10-10	Merck & Co. Inc.	2-unsaturated alkylthio-pen-2-em-3-carboxylic acids and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems
US4610823A (en) *	1983-01-25	1986-09-09	Merck & Co., Inc.	Process for preparing substituted 2-thioxopenams and 2-substituted thiopenems
US4675317A (en) *	1983-01-25	1987-06-23	Merck & Co., Inc.	2-unsaturated alkylthio-pen-2-em-3-carboxylic acids
ZA841781B (en) *	1983-03-14	1985-07-31	Schering Corp	Penim compounds,methods for their preparation and pharmaceutical compositions containing them
US4614738A (en) *	1983-03-25	1986-09-30	Schering Corporation	2-(N-heterocycloaliphaticthio)penems
US4619924A (en) *	1984-05-18	1986-10-28	Pfizer Inc.	2-alkylthiopenem derivatives
GB8321677D0 (en) *	1983-08-11	1983-09-14	Erba Farmitalia	Preparation of penems
US4614737A (en) *	1983-10-14	1986-09-30	Pfizer Inc.	2-dioxacycloalkylthiopenem derivatives
US4584133A (en) *	1983-11-07	1986-04-22	Schering Corporation	Process for the production of penems
JPH075463B2 (ja) *	1985-03-09	1995-01-25	サントリー株式会社	抗菌剤
US4673737A (en) *	1985-08-02	1987-06-16	Harvard University	7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
US4769451A (en) *	1985-08-15	1988-09-06	Bristol-Myers Company	Synthesis of carbapenems using n-substituted azetidinones
US4739047A (en) *	1985-10-17	1988-04-19	Pfizer Inc.	Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
GB2187448B (en) *	1986-03-06	1990-10-24	Erba Farmitalia	Penem derivatives
US4782145A (en) *	1986-06-02	1988-11-01	Pfizer Inc.	Process for penem derivatives
GB2195627A (en) *	1986-08-12	1988-04-13	Hoechst Uk Ltd	Penem derivatives
US4751297A (en) *	1987-03-20	1988-06-14	Pfizer Inc.	Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate

1989
- 1989-07-11 US US07/378,743 patent/US4992543A/en not_active Expired - Lifetime
- 1989-09-21 CA CA000612260A patent/CA1339845C/en not_active Expired - Fee Related
- 1989-10-04 PH PH39330A patent/PH26051A/en unknown
- 1989-10-12 DE DE68927085T patent/DE68927085T2/de not_active Expired - Fee Related
- 1989-10-12 ES ES89310500T patent/ES2091199T3/es not_active Expired - Lifetime
- 1989-10-12 EP EP89310500A patent/EP0365223B1/en not_active Expired - Lifetime
- 1989-10-12 IL IL9196189A patent/IL91961A/en not_active IP Right Cessation
- 1989-10-12 AT AT89310500T patent/ATE142212T1/de not_active IP Right Cessation
- 1989-10-16 MY MYPI89001416A patent/MY104239A/en unknown
- 1989-10-17 YU YU201889A patent/YU47073B/sh unknown
- 1989-10-18 AU AU43551/89A patent/AU606820B2/en not_active Ceased
- 1989-10-18 NZ NZ231055A patent/NZ231055A/en unknown
- 1989-10-18 FI FI894959A patent/FI94252C/fi not_active IP Right Cessation
- 1989-10-18 CN CN89107990A patent/CN1023015C/zh not_active Expired - Fee Related
- 1989-10-18 DK DK198905167A patent/DK174484B1/da active
- 1989-10-18 HU HU895352A patent/HU206216B/hu not_active IP Right Cessation
- 1989-10-18 NO NO894155A patent/NO174054C/no unknown
- 1989-10-18 IE IE334589A patent/IE75358B1/en not_active IP Right Cessation
- 1989-10-18 PT PT92022A patent/PT92022B/pt not_active IP Right Cessation
- 1989-10-18 KR KR1019890014993A patent/KR920001780B1/ko not_active Expired
- 1989-10-18 JP JP1271440A patent/JPH06104672B2/ja not_active Expired - Fee Related
- 1989-10-19 PL PL89281899A patent/PL163376B1/pl unknown
1990
- 1990-10-09 US US07/594,885 patent/US5286857A/en not_active Expired - Fee Related
1996
- 1996-10-16 GR GR960402724T patent/GR3021351T3/el unknown

Also Published As

Publication number	Publication date
GR3021351T3 (en)	1997-01-31
DK174484B1 (da)	2003-04-14
EP0365223A2 (en)	1990-04-25
DE68927085D1 (de)	1996-10-10
JPH06104672B2 (ja)	1994-12-21
PT92022B (pt)	1995-06-30
IE75358B1 (en)	1997-08-27
HU206216B (en)	1992-09-28
NO174054C (no)	1994-03-09
EP0365223A3 (en)	1991-04-10
CN1041944A (zh)	1990-05-09
KR900006344A (ko)	1990-05-08
PL163376B1 (pl)	1994-03-31
DK516789A (da)	1990-04-20
IL91961A (en)	1994-02-27
YU201889A (en)	1990-12-31
HUT52101A (en)	1990-06-28
IE893345L (en)	1990-04-19
IL91961A0 (en)	1990-07-12
ES2091199T3 (es)	1996-11-01
ATE142212T1 (de)	1996-09-15
CN1023015C (zh)	1993-12-08
HU895352D0 (en)	1990-01-28
DE68927085T2 (de)	1997-01-09
PH26051A (en)	1992-01-29
AU606820B2 (en)	1991-02-14
JPH02204494A (ja)	1990-08-14
FI94252B (fi)	1995-04-28
PT92022A (pt)	1990-04-30
KR920001780B1 (ko)	1992-03-02
FI94252C (fi)	1995-08-10
AU4355189A (en)	1990-08-02
NO174054B (no)	1993-11-29
MY104239A (en)	1994-02-28
NZ231055A (en)	1991-04-26
FI894959A0 (fi)	1989-10-18
US4992543A (en)	1991-02-12
US5286857A (en)	1994-02-15
DK516789D0 (da)	1989-10-18
CA1339845C (en)	1998-04-28
NO894155D0 (no)	1989-10-18
YU47073B (sh)	1994-12-28
EP0365223B1 (en)	1996-09-04

Publication	Publication Date	Title
NO961723D0 (no)	1996-04-29	Fremgangsmåte for fremstilling av eddiksyre ved karbonylering
TW232013B (no)	1994-10-11
NO894155L (no)	1990-04-20	Fremgangsmaate ved fremstilling av penem'er.
NO941957D0 (no)	1994-05-26	Fremgangsmåte for fremstilling av eddiksyre ved kontrollert oksydasjon et etan
FI873290A0 (fi)	1987-07-28	Foerfarande foer syntetisering av penem.
EP0976717A4 (en)	2000-05-17	CYCLOPENTENONE DERIVATIVES
DE69114765D1 (de)	1996-01-04	Verfahren für die Herstellung von bizyklischen beta-Laktamen.
AU621749B2 (en)	1992-03-19	Process for synthesizing beta-lactam compounds
NO863549L (no)	1987-03-09	Fremgangsmaate for fremstilling av 6-aminopenicillansyre 1,1-dioksyd ved oksydasjon av 6-amino penicillansyre.
HUT45065A (en)	1988-05-30	Process for producing 2-(1-oxo-3-thiolanyl)-2-penem antibiotics and pivaloyl-oxy-methyl-oxalyl- fluoride
MY105332A (en)	1994-09-30	Process for preparing penem esters
ATE66459T1 (de)	1991-09-15	Herstellungsverfahren von trifluormethylverbindungen.
SE9502381D0 (sv)	1995-06-30	Process for the production of enantiomerically-pure azetidine-2-carboxylic acid