NO895230L - Fremgangsmaate for fremstilling av nye dipeptider og tripeptider. - Google Patents

Fremgangsmaate for fremstilling av nye dipeptider og tripeptider.

Info

Publication number
NO895230L
NO895230L NO89895230A NO895230A NO895230L NO 895230 L NO895230 L NO 895230L NO 89895230 A NO89895230 A NO 89895230A NO 895230 A NO895230 A NO 895230A NO 895230 L NO895230 L NO 895230L
Authority
NO
Norway
Prior art keywords
tripeptides
procedure
preparation
dipeptides
new
Prior art date
Application number
NO89895230A
Other languages
English (en)
Norwegian (no)
Other versions
NO895230D0 (no
Inventor
Jay Donald Albright
Fuk-Wam Sum
Charles Frederick Howell
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO895230D0 publication Critical patent/NO895230D0/no
Publication of NO895230L publication Critical patent/NO895230L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO89895230A 1988-12-27 1989-12-22 Fremgangsmaate for fremstilling av nye dipeptider og tripeptider. NO895230L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29007988A 1988-12-27 1988-12-27

Publications (2)

Publication Number Publication Date
NO895230D0 NO895230D0 (no) 1989-12-22
NO895230L true NO895230L (no) 1990-06-28

Family

ID=23114455

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89895230A NO895230L (no) 1988-12-27 1989-12-22 Fremgangsmaate for fremstilling av nye dipeptider og tripeptider.

Country Status (11)

Country Link
EP (1) EP0376012A3 (fr)
JP (1) JPH02215799A (fr)
KR (1) KR900009688A (fr)
AU (1) AU4721489A (fr)
CA (1) CA2006374A1 (fr)
DK (1) DK661789A (fr)
FI (1) FI896238A7 (fr)
IL (1) IL92643A0 (fr)
NO (1) NO895230L (fr)
PT (1) PT92732A (fr)
ZA (1) ZA899924B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0427939A3 (en) * 1989-10-11 1991-11-06 American Cyanamid Company Renin inhibitors
JP2578044B2 (ja) * 1992-03-14 1997-02-05 呉羽化学工業株式会社 フェニルアラニン−グリシン誘導体、その製造方法、及びその誘導体を含有する抗腫瘍剤
US5618792A (en) * 1994-11-21 1997-04-08 Cortech, Inc. Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
US6159938A (en) * 1994-11-21 2000-12-12 Cortech, Inc. Serine protease inhibitors comprising α-keto heterocycles
TW200404789A (en) 1999-03-15 2004-04-01 Axys Pharm Inc Novel compounds and compositions as protease inhibitors
WO2002051983A2 (fr) 2000-12-22 2002-07-04 Axys Pharmaceuticals, Inc. Composes et compositions en tant qu'inhibiteurs de cathepsine
US7030116B2 (en) 2000-12-22 2006-04-18 Aventis Pharmaceuticals Inc. Compounds and compositions as cathepsin inhibitors
MXPA04002282A (es) 2001-09-14 2005-03-07 Axis Pharmaceutical Inc Nuevos compuestos y preparaciones como inhibidores de la catepsina.
EP1446392A1 (fr) 2001-11-14 2004-08-18 Aventis Pharmaceuticals, Inc. Nouveaux composes et compositions jouant le role d'inhibiteurs de cathepsine s

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0212550A3 (fr) * 1985-08-14 1989-05-10 G.D. Searle & Co. Amides dipeptides substitués
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors

Also Published As

Publication number Publication date
FI896238A7 (fi) 1990-06-28
EP0376012A3 (fr) 1992-05-06
ZA899924B (en) 1990-09-26
PT92732A (pt) 1990-06-29
FI896238A0 (fi) 1989-12-22
EP0376012A2 (fr) 1990-07-04
AU4721489A (en) 1990-07-05
NO895230D0 (no) 1989-12-22
JPH02215799A (ja) 1990-08-28
DK661789A (da) 1990-06-28
IL92643A0 (en) 1990-08-31
KR900009688A (ko) 1990-07-05
DK661789D0 (da) 1989-12-22
CA2006374A1 (fr) 1990-06-27

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