NO903565L - Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropyl)androst-5-en-3beta-ol-derivater. - Google Patents

Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropyl)androst-5-en-3beta-ol-derivater.

Info

Publication number: NO903565L
Authority: NO; Norway
Prior art keywords: beta; androst; substituted; 3beta; olive
Prior art date: 1989-08-15

Application number

NO90903565A

Other languages

English (en)

Norwegian (no)

Other versions

NO903565D0 (no

Inventor

Michael Richard Angelastro

Thomas Robert Blohm

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-15

Filing date

1990-08-14

Publication date

1991-02-18

1990-08-14 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1990-08-14 Publication of NO903565D0 publication Critical patent/NO903565D0/no

1991-02-18 Publication of NO903565L publication Critical patent/NO903565L/no

Links

238000000034 method Methods 0.000 title abstract 2
240000007817 Olea europaea Species 0.000 title 1
XIPUIGPNIDKXJU-UHFFFAOYSA-N [CH]1CC1 Chemical class [CH]1CC1 XIPUIGPNIDKXJU-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
238000006932 Simmons-Smith cyclopropanation reaction Methods 0.000 abstract 1
QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 abstract 1
239000003098 androgen Substances 0.000 abstract 1
230000001419 dependent effect Effects 0.000 abstract 1
150000002170 ethers Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0029—Ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

NO90903565A 1989-08-15 1990-08-14 Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropyl)androst-5-en-3beta-ol-derivater. NO903565L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/394,026 US4966897A (en)	1989-08-15	1989-08-15	4-substituted 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors

Publications (2)

Publication Number	Publication Date
NO903565D0 NO903565D0 (no)	1990-08-14
NO903565L true NO903565L (no)	1991-02-18

Family

ID=23557245

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO90903565A NO903565L (no)	1989-08-15	1990-08-14	Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropyl)androst-5-en-3beta-ol-derivater.

Country Status (22)

Country	Link
US (1)	US4966897A (de)
EP (1)	EP0413269B1 (de)
JP (1)	JP2879702B2 (de)
KR (1)	KR910004650A (de)
CN (1)	CN1050195A (de)
AT (1)	ATE138930T1 (de)
AU (1)	AU628210B2 (de)
CA (1)	CA2023008C (de)
DD (1)	DD298106A5 (de)
DE (1)	DE69027262T2 (de)
DK (1)	DK0413269T3 (de)
ES (1)	ES2090064T3 (de)
FI (1)	FI95711C (de)
GR (1)	GR3020797T3 (de)
HU (1)	HUT55030A (de)
IE (1)	IE902941A1 (de)
IL (1)	IL95359A (de)
NO (1)	NO903565L (de)
NZ (1)	NZ234855A (de)
PH (1)	PH27549A (de)
PT (1)	PT94994B (de)
ZA (1)	ZA906307B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4966898A (en) *	1989-08-15	1990-10-30	Merrell Dow Pharmaceuticals Inc.	4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
WO1994020520A1 (en) *	1993-03-10	1994-09-15	Magainin Pharmaceuticals Inc.	Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5486511A (en) *	1993-05-25	1996-01-23	Merrell Dow Pharmaceuticals Inc.	4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase
TW369521B (en) *	1993-09-17	1999-09-11	Smithkline Beecham Corp	Androstenone derivative
US5856535A (en) *	1994-08-18	1999-01-05	Magainin Pharmaceuticals, Inc.	Aminosterol ester compounds
US5840740A (en) *	1995-06-07	1998-11-24	Magainin Pharmaceuticals Inc.	Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5541322A (en) *	1994-10-14	1996-07-30	Glaxo Wellcome Inc.	Synthesis of 6-azaandrostenones
US5661141A (en) *	1995-03-27	1997-08-26	Petrow; Vladimir	19-oxygenated steroids as therapeutic agents
US5874597A (en) *	1995-06-07	1999-02-23	Magainin Pharmaceuticals, Inc.	Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5840936A (en) *	1995-06-07	1998-11-24	Magainin Pharmaceuticals Inc.	Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5994336A (en) *	1995-06-07	1999-11-30	Magainin Pharmaceuticals Inc.	Method of inhibiting proliferation of cells by administering an aminosterol compound
US6143738A (en) *	1995-06-07	2000-11-07	Magainin Pharmaceuticals, Inc.	Therapeutic uses for an aminosterol compound
US5792635A (en) *	1995-06-07	1998-08-11	Magainin Pharmaceuticals, Inc.	Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5763430A (en) *	1995-06-07	1998-06-09	Magainin Pharmaceuticals Inc.	Method of treating a viral infection by administering a steroid compound
US5795885A (en) *	1995-06-07	1998-08-18	Magainin Pharmaceuticals Inc.	Method of inhibiting profileration of cells by administering an aminosterol compound
US5847172A (en) *	1995-06-07	1998-12-08	Magainin Pharmaceuticals Inc.	Certain aminosterol compounds and pharmaceutical compositions including these compounds
US6365597B1 (en)	1996-02-14	2002-04-02	Aventis Pharmaceuticals Inc.	4-aza steroids
PT910382E (pt) *	1996-04-26	2003-10-31	Genaera Corp	Esqualamina em combinacao com outros agentes anti-cancro para o tratamento de tumores
US6596712B2 (en)	1996-04-26	2003-07-22	Genaera Corporation	Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
US6262283B1 (en)	1996-12-06	2001-07-17	Magainin Pharmaceuticals Inc.	Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
DK1274718T3 (da) *	2000-04-12	2007-02-12	Genaera Corp	En fremgangsmåde til forberedelse af 7.alpha.-hydroxy 3-aminosubstituerede steroler vee en ubeskyttet 7.alpha.-hydroxy gruppe
JP2007297879A (ja) *	2006-05-02	2007-11-15	Central Glass Co Ltd	電磁波吸収板

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3475464A (en) *	1966-11-07	1969-10-28	Syntex Corp	Process for the preparation of steroids and novel intermediates thereof
US4139617A (en) *	1974-05-13	1979-02-13	Richardson-Merrell Inc.	19-Oxygenated-androst-5-enes for the enhancement of libido
US4891367A (en) *	1987-04-22	1990-01-02	Merrell Dow Pharmaceuticals Inc.	17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
US4966898A (en) *	1989-08-15	1990-10-30	Merrell Dow Pharmaceuticals Inc.	4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors

1989
- 1989-08-15 US US07/394,026 patent/US4966897A/en not_active Expired - Fee Related
1990
- 1990-08-09 JP JP2209388A patent/JP2879702B2/ja not_active Expired - Fee Related
- 1990-08-09 ZA ZA906307A patent/ZA906307B/xx unknown
- 1990-08-09 AU AU60878/90A patent/AU628210B2/en not_active Ceased
- 1990-08-09 CA CA002023008A patent/CA2023008C/en not_active Expired - Fee Related
- 1990-08-10 DE DE69027262T patent/DE69027262T2/de not_active Expired - Fee Related
- 1990-08-10 NZ NZ234855A patent/NZ234855A/xx unknown
- 1990-08-10 DK DK90115390.8T patent/DK0413269T3/da active
- 1990-08-10 EP EP90115390A patent/EP0413269B1/de not_active Expired - Lifetime
- 1990-08-10 ES ES90115390T patent/ES2090064T3/es not_active Expired - Lifetime
- 1990-08-10 AT AT90115390T patent/ATE138930T1/de not_active IP Right Cessation
- 1990-08-13 IL IL9535990A patent/IL95359A/en not_active IP Right Cessation
- 1990-08-14 KR KR1019900012534A patent/KR910004650A/ko not_active Ceased
- 1990-08-14 NO NO90903565A patent/NO903565L/no unknown
- 1990-08-14 IE IE294190A patent/IE902941A1/en not_active IP Right Cessation
- 1990-08-14 PT PT94994A patent/PT94994B/pt not_active IP Right Cessation
- 1990-08-14 HU HU905005A patent/HUT55030A/hu unknown
- 1990-08-15 PH PH41035A patent/PH27549A/en unknown
- 1990-08-15 FI FI904036A patent/FI95711C/fi not_active IP Right Cessation
- 1990-08-15 DD DD90343475A patent/DD298106A5/de unknown
- 1990-08-15 CN CN90107578A patent/CN1050195A/zh active Pending
1996
- 1996-08-14 GR GR960402177T patent/GR3020797T3/el unknown

Also Published As

Publication number	Publication date
DE69027262D1 (de)	1996-07-11
AU6087890A (en)	1991-02-21
HUT55030A (en)	1991-04-29
IL95359A (en)	1995-08-31
NZ234855A (en)	1992-11-25
DK0413269T3 (da)	1996-06-24
FI95711B (fi)	1995-11-30
PT94994B (pt)	1997-05-28
DD298106A5 (de)	1992-02-06
US4966897A (en)	1990-10-30
EP0413269A3 (en)	1992-05-20
FI95711C (fi)	1996-03-11
AU628210B2 (en)	1992-09-10
PT94994A (pt)	1991-04-18
HU905005D0 (en)	1991-01-28
FI904036A0 (fi)	1990-08-15
JPH0383996A (ja)	1991-04-09
KR910004650A (ko)	1991-03-29
CA2023008C (en)	2001-05-15
NO903565D0 (no)	1990-08-14
ES2090064T3 (es)	1996-10-16
CA2023008A1 (en)	1991-02-16
PH27549A (en)	1993-08-18
EP0413269A2 (de)	1991-02-20
IE902941A1 (en)	1991-02-27
IL95359A0 (en)	1991-06-30
ATE138930T1 (de)	1996-06-15
ZA906307B (en)	1991-06-26
GR3020797T3 (en)	1996-11-30
DE69027262T2 (de)	1996-10-02
JP2879702B2 (ja)	1999-04-05
CN1050195A (zh)	1991-03-27
EP0413269B1 (de)	1996-06-05

Publication	Publication Date	Title
NO903565L (no)	1991-02-18	Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropyl)androst-5-en-3beta-ol-derivater.
NO903564L (no)	1991-02-18	Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropylamino)androst-5-en-3beta-ol-derivater.
NO881746D0 (no)	1988-04-21	Fremgangsmaate for fremstilling av 17beta-(cyclopropylamino) androst-5-en-3beta-ol og beslektede forbindelser.
PL293065A1 (en)	1992-08-10	Method of obtaining novel derivatives of chromane and thiochromane
HU9203761D0 (en)	1993-03-29	Method for producing substituted pyridine derivatives
NO881745L (no)	1988-10-24	Fremgangsmaate for fremstilling av 17beta-(cyclopropyloxy)androst-5-en-3beta-ol og beslektede forbindelser.