NO905245L - Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser.

Info

Publication number: NO905245L
Authority: NO; Norway
Prior art keywords: alkyl; phenyl; group; formula; phenylalkyl
Prior art date: 1989-12-05

Application number

NO90905245A

Other languages

English (en)

Norwegian (no)

Other versions

NO905245D0 (no

Inventor

Stuart Dennett Mills

Rodney Brian Hargreaves

Bernard Joseph Mcloughlin

Original Assignee

Ici Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-05

Filing date

1990-12-04

Publication date

1991-06-06

1989-12-05 Priority claimed from GB898927462A external-priority patent/GB8927462D0/en

1989-12-22 Priority claimed from GB898929020A external-priority patent/GB8929020D0/en

1990-12-04 Application filed by Ici Plc filed Critical Ici Plc

1990-12-04 Publication of NO905245D0 publication Critical patent/NO905245D0/no

1991-06-06 Publication of NO905245L publication Critical patent/NO905245L/no

Links

150000002391 heterocyclic compounds Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 7
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 6
150000001875 compounds Chemical class 0.000 abstract 4
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical group C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
125000003282 alkyl amino group Chemical group 0.000 abstract 2
125000002947 alkylene group Chemical group 0.000 abstract 2
230000009286 beneficial effect Effects 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
125000005647 linker group Chemical group 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
-1 oxy, thio, carbonyl Chemical group 0.000 abstract 2
125000003884 phenylalkyl group Chemical group 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000004076 pyridyl group Chemical group 0.000 abstract 2
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
239000005977 Ethylene Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
210000000748 cardiovascular system Anatomy 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000000654 isopropylidene group Chemical group C(C)(C)=* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
210000001013 sinoatrial node Anatomy 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
- C07D251/18—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom with nitrogen atoms directly attached to the two other ring carbon atoms, e.g. guanamines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)
Separation Using Semi-Permeable Membranes (AREA)
Detergent Compositions (AREA)
Air Bags (AREA)

NO90905245A 1989-12-05 1990-12-04 Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser. NO905245L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898927462A GB8927462D0 (en)	1989-12-05	1989-12-05	Heterocyclic compounds
GB898929020A GB8929020D0 (en)	1989-12-22	1989-12-22	Aminoheterocycles

Publications (2)

Publication Number	Publication Date
NO905245D0 NO905245D0 (no)	1990-12-04
NO905245L true NO905245L (no)	1991-06-06

Family

ID=26296312

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO90905245A NO905245L (no)	1989-12-05	1990-12-04	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser.

Country Status (20)

Country	Link
US (2)	US5332737A (de)
EP (1)	EP0431856B1 (de)
JP (1)	JPH03181473A (de)
KR (1)	KR910011836A (de)
AT (1)	ATE124937T1 (de)
AU (1)	AU640709B2 (de)
CA (1)	CA2031259A1 (de)
DE (1)	DE69020868T2 (de)
DK (1)	DK0431856T3 (de)
ES (1)	ES2074142T3 (de)
FI (1)	FI905918A7 (de)
GB (1)	GB9024617D0 (de)
HU (1)	HU206097B (de)
IE (1)	IE904116A1 (de)
IL (1)	IL96383A0 (de)
MY (1)	MY106091A (de)
NO (1)	NO905245L (de)
NZ (1)	NZ236147A (de)
PT (1)	PT96075A (de)
ZW (1)	ZW18290A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002322720B2 (en)	2001-07-25	2008-11-13	Raptor Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
US7250416B2 (en) *	2005-03-11	2007-07-31	Supergen, Inc.	Azacytosine analogs and derivatives
CA2789262C (en)	2005-04-28	2016-10-04	Proteus Digital Health, Inc.	Pharma-informatics system
EP2063905B1 (de)	2006-09-18	2014-07-30	Raptor Pharmaceutical Inc	Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
US20090040326A1 (en) *	2007-08-09	2009-02-12	Micron Technology, Inc	Methods and apparatuses for supplying current using a digital sequence
TR201908314T4 (tr)	2009-02-20	2019-06-21	2 Bbb Medicines B V	Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko)	2009-05-06	2018-12-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB814947A (en)	1954-08-16	1959-06-17	Geigy Ag J R	Improvements in and relating to plant growth influencing compositions
NL131196C (de)	1966-07-16
US3729468A (en) *	1967-07-20	1973-04-24	Kowa Co	Triazine derivatives and process for their preparation
BE726947A (de) *	1968-04-10	1969-07-01
US4312988A (en) *	1980-11-10	1982-01-26	American Cyanamid Company	Synthesis of hydroxy functional melamine derivatives
FR2524467A1 (fr) *	1982-03-30	1983-10-07	Adir	Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2544315B1 (fr) *	1983-04-12	1985-07-05	Adir	Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant
DE3611427A1 (de) *	1986-04-05	1987-10-08	Hoechst Ag	Bis-tertiaerbutylamino-substituierte 1,3,5-triazinderivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
DE3639563A1 (de) *	1986-11-20	1988-06-01	Basf Ag	N-arylsulfonyl-n'-pyrimidyl(triazinyl) -harnstoffe
AU621082B2 (en) *	1988-02-08	1992-03-05	Ciba-Geigy Ag	Tetramethylpiperidino-s-triazines
GB8808071D0 (en)	1988-04-07	1988-05-11	Shell Int Research	Triazine herbicides
GB8819494D0 (en) *	1988-08-16	1988-09-21	Ucb Sa	Use of 2-amino-4-morpholino-6-propyl-1 3 5-triazines for preparation of psychotropic medicaments
GB8819493D0 (en) *	1988-08-16	1988-09-21	Ucb Sa	2-amino-4-morpholino-6-propyl-1 3 5-triazines

1990
- 1990-11-13 GB GB909024617A patent/GB9024617D0/en active Pending
- 1990-11-14 IE IE411690A patent/IE904116A1/en unknown
- 1990-11-18 IL IL96383A patent/IL96383A0/xx unknown
- 1990-11-19 AU AU66713/90A patent/AU640709B2/en not_active Ceased
- 1990-11-20 NZ NZ236147A patent/NZ236147A/en unknown
- 1990-11-21 HU HU907224A patent/HU206097B/hu not_active IP Right Cessation
- 1990-11-26 ZW ZW182/90A patent/ZW18290A1/xx unknown
- 1990-11-30 DK DK90313079.7T patent/DK0431856T3/da active
- 1990-11-30 FI FI905918A patent/FI905918A7/fi not_active Application Discontinuation
- 1990-11-30 DE DE69020868T patent/DE69020868T2/de not_active Expired - Fee Related
- 1990-11-30 CA CA002031259A patent/CA2031259A1/en not_active Abandoned
- 1990-11-30 ES ES90313079T patent/ES2074142T3/es not_active Expired - Lifetime
- 1990-11-30 EP EP90313079A patent/EP0431856B1/de not_active Expired - Lifetime
- 1990-11-30 AT AT90313079T patent/ATE124937T1/de not_active IP Right Cessation
- 1990-11-30 JP JP2336882A patent/JPH03181473A/ja active Pending
- 1990-12-03 US US07/621,677 patent/US5332737A/en not_active Expired - Fee Related
- 1990-12-04 PT PT96075A patent/PT96075A/pt not_active Application Discontinuation
- 1990-12-04 MY MYPI90002134A patent/MY106091A/en unknown
- 1990-12-04 NO NO90905245A patent/NO905245L/no unknown
- 1990-12-05 KR KR1019900020008A patent/KR910011836A/ko not_active Withdrawn
1995
- 1995-06-07 US US08/488,458 patent/US5574037A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU640709B2 (en)	1993-09-02
MY106091A (en)	1995-03-31
IL96383A0 (en)	1991-08-16
FI905918A0 (fi)	1990-11-30
US5332737A (en)	1994-07-26
US5574037A (en)	1996-11-12
GB9024617D0 (en)	1991-01-02
HU206097B (en)	1992-08-28
HU907224D0 (en)	1991-05-28
EP0431856A3 (en)	1992-01-15
ATE124937T1 (de)	1995-07-15
CA2031259A1 (en)	1991-06-06
IE904116A1 (en)	1991-06-05
ZW18290A1 (en)	1991-10-02
KR910011836A (ko)	1991-08-07
EP0431856A2 (de)	1991-06-12
EP0431856B1 (de)	1995-07-12
DE69020868D1 (de)	1995-08-17
FI905918A7 (fi)	1991-06-06
DK0431856T3 (da)	1995-12-11
NZ236147A (en)	1993-12-23
JPH03181473A (ja)	1991-08-07
ES2074142T3 (es)	1995-09-01
NO905245D0 (no)	1990-12-04
PT96075A (pt)	1991-09-30
AU6671390A (en)	1991-06-13
HUT58305A (en)	1992-02-28
DE69020868T2 (de)	1995-11-30

Publication	Publication Date	Title
MY105637A (en)	1994-11-30	Pyrimidine derivatives
NO905245D0 (no)	1990-12-04	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser.
NO905378D0 (no)	1990-12-12	Fremgangsmaate for fremstilling av terapeutisk aktive diazinderivater.
FI903511A0 (fi)	1990-07-11	Pyrrolo (2,1-b) tiazolderivat.
DE69024154D1 (de)	1996-01-25	Pyrimidoindolderivate und Verfahren zu ihrer Herstellung