NO905255L - Fremgangsmaate for fremstilling av heterocyklisk substituerte acylaminotiazoler. - Google Patents
Fremgangsmaate for fremstilling av heterocyklisk substituerte acylaminotiazoler.Info
- Publication number
- NO905255L NO905255L NO90905255A NO905255A NO905255L NO 905255 L NO905255 L NO 905255L NO 90905255 A NO90905255 A NO 90905255A NO 905255 A NO905255 A NO 905255A NO 905255 L NO905255 L NO 905255L
- Authority
- NO
- Norway
- Prior art keywords
- acylaminotiazoles
- procedure
- preparation
- heterocyclic substituted
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8916122A FR2655344B1 (fr) | 1989-12-06 | 1989-12-06 | Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant. |
| FR9005669A FR2661677B1 (fr) | 1990-05-04 | 1990-05-04 | Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO905255D0 NO905255D0 (no) | 1990-12-05 |
| NO905255L true NO905255L (no) | 1991-06-07 |
| NO179584B NO179584B (no) | 1996-07-29 |
| NO179584C NO179584C (no) | 1996-11-06 |
Family
ID=26227714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO905255A NO179584C (no) | 1989-12-06 | 1990-12-05 | Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-acylaminotiazoler |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5189049A (no) |
| EP (1) | EP0432040B2 (no) |
| JP (2) | JP2760903B2 (no) |
| KR (1) | KR0147281B1 (no) |
| AR (1) | AR248138A1 (no) |
| AT (1) | ATE109145T1 (no) |
| AU (1) | AU628696B2 (no) |
| CA (1) | CA2031463C (no) |
| DE (1) | DE69011059T3 (no) |
| DK (1) | DK0432040T3 (no) |
| ES (1) | ES2057490T5 (no) |
| FI (1) | FI94249C (no) |
| GR (1) | GR3025940T3 (no) |
| HU (2) | HU218276B (no) |
| IE (1) | IE68593B1 (no) |
| IL (1) | IL96577A (no) |
| LV (1) | LV5802B4 (no) |
| MX (1) | MX9203027A (no) |
| NO (1) | NO179584C (no) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677356B1 (fr) * | 1991-06-05 | 1995-03-17 | Sanofi Sa | Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant. |
| US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
| FR2701708B1 (fr) * | 1993-02-19 | 1995-05-19 | Sanofi Elf | Dérivés de 2-amido-4-phénylthiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament. |
| FR2703995B1 (fr) * | 1993-04-16 | 1995-07-21 | Sanofi Elf | 5-acylamino 1,2,4-thiadiazoles, leur preparation et compositions pharmaceutiques en contenant. |
| FR2714059B1 (fr) * | 1993-12-21 | 1996-03-08 | Sanofi Elf | Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| FR2768737B1 (fr) * | 1997-09-19 | 2000-05-19 | Sanofi Sa | Derives de carboxamidothiazoles, leur preparation, les compositions pharmaceutiques en contenant |
| CO4970713A1 (es) * | 1997-09-19 | 2000-11-07 | Sanofi Synthelabo | Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen |
| UA66810C2 (uk) * | 1997-10-27 | 2004-06-15 | Агорон Фармацевтикалз Інк. | Похідні 4-амінотіазолу та композиції на їх основі як інгібітори циклінозалежних кіназ |
| FR2781227B1 (fr) | 1998-07-20 | 2002-02-22 | Sanofi Sa | Procede pour la preparation du sel potassique du lintitript |
| US20040037818A1 (en) * | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
| DE19908537A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Verwendung von polycyclischen 2-Amino-Thiazol Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas |
| DE19908538A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen |
| US6989379B1 (en) | 1999-04-22 | 2006-01-24 | H. Lundbick A/S | Selective NPY (Y5) antagonists |
| US6340683B1 (en) | 1999-04-22 | 2002-01-22 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (triazines) |
| US6218408B1 (en) | 1999-06-30 | 2001-04-17 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
| DK1183245T3 (da) | 1999-04-22 | 2007-09-24 | Lundbeck & Co As H | Selektive NPY(Y5)-antagonister |
| US7273880B2 (en) | 1999-06-30 | 2007-09-25 | H. Lunbeck A/S | Selective NPY (Y5) antagonists |
| US6225330B1 (en) | 1999-06-30 | 2001-05-01 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
| US6222040B1 (en) | 1999-06-30 | 2001-04-24 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
| US6214853B1 (en) | 1999-06-30 | 2001-04-10 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
| AU2001234958A1 (en) | 2000-02-11 | 2001-08-20 | Bristol-Myers Squibb Company | Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases |
| US7732484B2 (en) * | 2000-08-01 | 2010-06-08 | University Of Virginia Patent Foundation | Use of selective adenosine A1 receptor allosteric enhancers to manipulate angiogenesis |
| ES2315350T3 (es) * | 2001-01-12 | 2009-04-01 | Waratah Pharmaceuticals Inc. | Composiciones para la introduccion de la neogenesis de islotes, que contienen unos ligandos para el receptor de gastrina/cck y ligandos para el receptor de efg. |
| US7169931B2 (en) * | 2001-01-26 | 2007-01-30 | Shionogi & Co., Ltd. | Cyclic compounds exhibiting thrombopoietin receptor agonism |
| US20040077697A1 (en) * | 2001-02-02 | 2004-04-22 | Hiroyuki Koshio | 2-Acylaminothiazole derivative or its salt |
| EP1314733A1 (en) * | 2001-11-22 | 2003-05-28 | Aventis Pharma Deutschland GmbH | Indole-2-carboxamides as factor Xa inhibitors |
| EP1583530A4 (en) * | 2002-01-16 | 2008-07-23 | Univ Virginia | 2-AMINOTHIAZOLE ALLOSTERIC AMPLIFIERS OF A1 ADENOSINE RECEPTORS |
| US7638536B2 (en) * | 2002-01-18 | 2009-12-29 | Astellas Pharma Inc. | 2-Acylaminothiazole derivative or salt thereof |
| US20050261298A1 (en) * | 2002-01-18 | 2005-11-24 | David Solow-Cordero | Methods of treating conditions associated with an Edg-7 receptor |
| CA2477604A1 (en) | 2002-03-13 | 2003-09-25 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
| IL165242A0 (en) * | 2002-05-24 | 2005-12-18 | Waratah Pharmaceuticals Inc | Treatment for diabetes |
| EP1837031B1 (en) * | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
| AU2003243921B2 (en) | 2002-06-27 | 2009-05-07 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
| US20040229810A1 (en) * | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
| US20080039379A1 (en) * | 2003-05-27 | 2008-02-14 | Waratah Pharmaceuticals, Inc. | Compositions Comprising Gastrin Compounds and Their Use in Diabetes |
| US7737133B2 (en) * | 2003-09-03 | 2010-06-15 | Agi Therapeutics Ltd. | Formulations and methods of treating inflammatory bowel disease |
| EP1532980A1 (en) * | 2003-11-24 | 2005-05-25 | Novo Nordisk A/S | N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes |
| JP4638355B2 (ja) * | 2003-12-26 | 2011-02-23 | 協和発酵キリン株式会社 | チアゾール誘導体 |
| PT1723128E (pt) | 2004-01-06 | 2013-02-27 | Novo Nordisk As | Heteroaril-ureias e o seu uso como activadores da glicoquinase |
| NZ552650A (en) * | 2004-08-05 | 2010-09-30 | Hoffmann La Roche | Substituted N-acyl-2-aminothiazoles |
| RU2007109073A (ru) * | 2004-08-13 | 2008-09-20 | Дженентек, Инк. (Us) | Ингибиторы для атф-зависимого фермента на основе тиазола |
| WO2006080406A1 (ja) * | 2005-01-28 | 2006-08-03 | Taisho Pharmaceutical Co., Ltd. | 三環性化合物 |
| US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| WO2006084033A1 (en) * | 2005-02-03 | 2006-08-10 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| US20100280023A1 (en) * | 2005-06-23 | 2010-11-04 | Kyowa Hakko Kogyo Co., Ltd. | Thiazole derivatives |
| JP2009500378A (ja) | 2005-07-08 | 2009-01-08 | ノボ・ノルデイスク・エー/エス | グルコキナーゼ活性化剤としてのジシクロアルキルカルバモイル尿素 |
| BRPI0612996A2 (pt) | 2005-07-14 | 2010-12-14 | Novo Nordisk As | ativadores de urÉia glucocinase |
| JP2009514941A (ja) * | 2005-11-08 | 2009-04-09 | アステラス製薬株式会社 | 血小板減少症を治療する化合物および方法 |
| RU2008128453A (ru) * | 2005-12-12 | 2010-01-20 | Дженелабс Текнолоджис, Инк. (Us) | Соединение n-(5-членных арил)-амидов, фармацевтическая композиция с противовирусной активностью на их основе, способ лечения или профилактики вирусной инфекции с их помощью и способ их получения |
| CN101096363B (zh) * | 2006-06-27 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 2,4,5-三取代噻唑类化合物、其制备方法、药物组合物及其制药用途 |
| WO2008021283A2 (en) * | 2006-08-08 | 2008-02-21 | Akarx, Inc. | Compositions and methods for increasing blood platelet levels in humans |
| US8138185B2 (en) | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
| AU2008204530B2 (en) | 2007-01-11 | 2013-08-01 | Vtv Therapeutics Llc | Urea glucokinase activators |
| CN102014897B (zh) | 2008-04-21 | 2015-08-05 | 西格纳姆生物科学公司 | 化合物、组合物和其制备方法 |
| EP2464352A1 (en) * | 2009-08-14 | 2012-06-20 | Eisai Inc. | Use of e5501 for stimulating platelet production |
| DE102011083271A1 (de) * | 2011-09-23 | 2013-03-28 | Beiersdorf Ag | Aromatische Amidothiazole, deren kosmetische oder dermatologische Verwendung sowie kosmetische oder dermatologische Zubereitungen mit einem Gehalt an solchen Aromatischen Amidothiazolen |
| WO2014196793A1 (en) * | 2013-06-05 | 2014-12-11 | C&C Research Laboratories | Heterocyclic derivatives and use thereof |
| ES2634628T3 (es) | 2013-07-02 | 2017-09-28 | Bristol-Myers Squibb Company | Derivados tricíclicos de pirido-carboxamida como inhibidores ROCK |
| EP3016951B1 (en) | 2013-07-02 | 2017-05-31 | Bristol-Myers Squibb Company | Tricyclic pyrido-carboxamide derivatives as rock inhibitors |
| CN109111427B (zh) * | 2017-06-22 | 2023-06-02 | 中国科学院广州生物医药与健康研究院 | 一种吲哚类化合物及其应用 |
| AU2019287437A1 (en) | 2018-06-12 | 2020-09-10 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
| WO2021167840A1 (en) | 2020-02-18 | 2021-08-26 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
| CN116194442A (zh) | 2020-06-08 | 2023-05-30 | 维特卫治疗有限责任公司 | {2-[3-环己基-3-(反式-4-丙氧基-环己基)-脲基]-噻唑-5-基硫烷基}-乙酸的盐或共晶体及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2340092A2 (fr) * | 1976-02-09 | 1977-09-02 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| AT367871B (de) * | 1980-05-16 | 1982-08-10 | Hoerbiger Ventilwerke Ag | Anordnung zur selbsttaetigen druckentlastung von verdichtern |
| FR2482596A1 (fr) * | 1980-05-19 | 1981-11-20 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament |
| JPS5978171A (ja) * | 1982-10-26 | 1984-05-04 | Ikeda Mohandou:Kk | 複素環式化合物 |
| FR2566405B1 (fr) * | 1984-06-25 | 1986-09-26 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus |
| ATE67185T1 (de) * | 1985-07-09 | 1991-09-15 | Pfizer | Substituierte oxindol-3-carboxamine als entzuendungshemmendes und schmerzstillendes mittel. |
| DE3705934A1 (de) * | 1987-02-25 | 1988-09-08 | Nattermann A & Cie | Indolyl-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4971978A (en) * | 1987-09-21 | 1990-11-20 | Nadzan Alex M | Derivatives of D-glutamic acid and D-aspartic acid |
| US4992437A (en) * | 1987-12-22 | 1991-02-12 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienodiazepine compounds and their pharmaceutical use |
| GB8804448D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
| GB8820231D0 (en) * | 1988-08-25 | 1988-09-28 | Fujisawa Pharmaceutical Co | New benzazole compounds processes for preparation thereof & pharmaceutical composition comprising same |
| FR2701708B1 (fr) * | 1993-02-19 | 1995-05-19 | Sanofi Elf | Dérivés de 2-amido-4-phénylthiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament. |
| FR2703995B1 (fr) * | 1993-04-16 | 1995-07-21 | Sanofi Elf | 5-acylamino 1,2,4-thiadiazoles, leur preparation et compositions pharmaceutiques en contenant. |
-
1990
- 1990-11-29 IE IE431090A patent/IE68593B1/en not_active IP Right Cessation
- 1990-12-03 FI FI905941A patent/FI94249C/fi not_active IP Right Cessation
- 1990-12-04 CA CA002031463A patent/CA2031463C/en not_active Expired - Fee Related
- 1990-12-05 AT AT90403458T patent/ATE109145T1/de not_active IP Right Cessation
- 1990-12-05 DK DK90403458.4T patent/DK0432040T3/da active
- 1990-12-05 DE DE69011059T patent/DE69011059T3/de not_active Expired - Fee Related
- 1990-12-05 US US07/622,620 patent/US5189049A/en not_active Ceased
- 1990-12-05 JP JP2406318A patent/JP2760903B2/ja not_active Expired - Lifetime
- 1990-12-05 AU AU67779/90A patent/AU628696B2/en not_active Ceased
- 1990-12-05 EP EP90403458A patent/EP0432040B2/fr not_active Expired - Lifetime
- 1990-12-05 ES ES90403458T patent/ES2057490T5/es not_active Expired - Lifetime
- 1990-12-05 AR AR90318535A patent/AR248138A1/es active
- 1990-12-05 NO NO905255A patent/NO179584C/no not_active IP Right Cessation
- 1990-12-05 HU HU075/90A patent/HU218276B/hu not_active IP Right Cessation
- 1990-12-06 IL IL9657790A patent/IL96577A/en not_active IP Right Cessation
- 1990-12-06 KR KR1019900020116A patent/KR0147281B1/ko not_active Expired - Fee Related
-
1992
- 1992-06-19 MX MX9203027A patent/MX9203027A/es unknown
-
1995
- 1995-06-29 HU HU95P/P00526P patent/HU211866A9/hu unknown
- 1995-09-11 US US08/526,079 patent/USRE37094E1/en not_active Expired - Lifetime
-
1996
- 1996-07-16 LV LV960248A patent/LV5802B4/xx unknown
-
1997
- 1997-08-06 JP JP9212074A patent/JP3035253B2/ja not_active Expired - Lifetime
-
1998
- 1998-01-16 GR GR980400110T patent/GR3025940T3/el unknown
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