NO912772L - Pyrazolidinon cck, gastrinantagonister og farmasoeytiske formuleringer derav. - Google Patents
Pyrazolidinon cck, gastrinantagonister og farmasoeytiske formuleringer derav.Info
- Publication number
- NO912772L NO912772L NO91912772A NO912772A NO912772L NO 912772 L NO912772 L NO 912772L NO 91912772 A NO91912772 A NO 91912772A NO 912772 A NO912772 A NO 912772A NO 912772 L NO912772 L NO 912772L
- Authority
- NO
- Norway
- Prior art keywords
- cck
- pyrazolidinon
- gastrin
- pharmaceutical forms
- receptors
- Prior art date
Links
- 102100021022 Gastrin Human genes 0.000 title 1
- 108010052343 Gastrins Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 title 1
- NDGRWYRVNANFNB-UHFFFAOYSA-N pyrazolidin-3-one Chemical compound O=C1CCNN1 NDGRWYRVNANFNB-UHFFFAOYSA-N 0.000 title 1
- 108010089448 Cholecystokinin B Receptor Proteins 0.000 abstract 2
- 102000052874 Gastrin receptors Human genes 0.000 abstract 2
- 102000004859 Cholecystokinin Receptors Human genes 0.000 abstract 1
- 108090001085 Cholecystokinin Receptors Proteins 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 235000021229 appetite regulation Nutrition 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000000496 pancreas Anatomy 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 210000000813 small intestine Anatomy 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55348990A | 1990-07-17 | 1990-07-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO912772D0 NO912772D0 (no) | 1991-07-15 |
| NO912772L true NO912772L (no) | 1992-01-20 |
Family
ID=24209587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO91912772A NO912772L (no) | 1990-07-17 | 1991-07-15 | Pyrazolidinon cck, gastrinantagonister og farmasoeytiske formuleringer derav. |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0467614A1 (cs) |
| JP (1) | JPH04230367A (cs) |
| KR (1) | KR960005950B1 (cs) |
| CN (1) | CN1032000C (cs) |
| AU (2) | AU644190B2 (cs) |
| BR (1) | BR9103042A (cs) |
| CA (1) | CA2046672A1 (cs) |
| CS (1) | CS219391A3 (cs) |
| FI (1) | FI913431A7 (cs) |
| HU (1) | HUT58296A (cs) |
| IE (1) | IE912489A1 (cs) |
| IL (1) | IL98785A (cs) |
| MX (1) | MX9100164A (cs) |
| NO (1) | NO912772L (cs) |
| NZ (1) | NZ238912A (cs) |
| PT (1) | PT98323A (cs) |
| RU (1) | RU2076100C1 (cs) |
| YU (1) | YU124391A (cs) |
| ZA (1) | ZA915372B (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5191084A (en) * | 1991-05-01 | 1993-03-02 | American Home Products Corporation | Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents |
| US5153191A (en) * | 1991-08-20 | 1992-10-06 | Warner-Lambert Company | Cholecystokinin antagonists useful for treating depression |
| US5399708A (en) * | 1993-11-12 | 1995-03-21 | Eli Lilly And Company | Pyrazolidin-3-one derivatives |
| GB0011095D0 (en) * | 2000-05-08 | 2000-06-28 | Black James Foundation | astrin and cholecystokinin receptor ligands (III) |
| IL156445A0 (en) * | 2001-01-26 | 2004-01-04 | Schering Corp | Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
| PE20020856A1 (es) * | 2001-02-13 | 2002-11-11 | Aventis Pharma Gmbh | 1,2,3,4-tetrahidronaftil aminas aciladas |
| UA79804C2 (en) | 2002-07-03 | 2007-07-25 | Janssen Pharmaceutica Nv | Cck-1 receptor modulators |
| GB0312368D0 (en) * | 2003-05-30 | 2003-07-02 | Univ Aston | Novel ureido- and amido-pyrazolone derivatives |
| US8410135B2 (en) * | 2007-06-15 | 2013-04-02 | Solvay Pharmaceuticals B.V. | 4,5 dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators |
| BR112021009610A2 (pt) | 2018-11-20 | 2021-08-10 | Sironax Ltd | composto, composição farmacêutica, uso de um composto ou composição, e, método de inibir necrose, ferroptose, rip1 humana ou indicações relacionadas |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE530886A (cs) * | 1953-08-03 | |||
| FR82186E (fr) * | 1959-04-10 | 1964-01-04 | Kodak Pathe | Nouveau produit photographique et procédé pour le traitement de ce produit |
| FR2529786A1 (fr) * | 1982-07-12 | 1984-01-13 | Nativelle Sa Ets | Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation |
| DE3407506A1 (de) * | 1984-03-01 | 1985-09-05 | A. Nattermann & Cie GmbH, 5000 Köln | 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazoline, verfahren zu ihrer herstellung und deren verwendung |
| EP0166355A2 (en) * | 1984-06-26 | 1986-01-02 | Merck & Co. Inc. | Substituted aminophenyl compounds and acylaminophenyl compounds and pharmaceutical compositions containing them |
| US5089622A (en) * | 1988-12-12 | 1992-02-18 | Mitsui Toatsu Chemicals Incorporated | (-)-2-pyrazoline compounds and therapeutic agent for cerebrovascular disorders containing the same as effective ingredient |
| US5191084A (en) * | 1991-05-01 | 1993-03-02 | American Home Products Corporation | Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents |
-
1991
- 1991-07-10 CA CA002046672A patent/CA2046672A1/en not_active Abandoned
- 1991-07-10 NZ NZ238912A patent/NZ238912A/en unknown
- 1991-07-10 ZA ZA915372A patent/ZA915372B/xx unknown
- 1991-07-10 IL IL9878591A patent/IL98785A/en not_active IP Right Cessation
- 1991-07-11 MX MX9100164A patent/MX9100164A/es unknown
- 1991-07-12 AU AU80409/91A patent/AU644190B2/en not_active Ceased
- 1991-07-15 EP EP91306374A patent/EP0467614A1/en not_active Ceased
- 1991-07-15 KR KR1019910012030A patent/KR960005950B1/ko not_active Expired - Lifetime
- 1991-07-15 NO NO91912772A patent/NO912772L/no unknown
- 1991-07-15 HU HU912376A patent/HUT58296A/hu unknown
- 1991-07-15 PT PT98323A patent/PT98323A/pt not_active Application Discontinuation
- 1991-07-15 CS CS912193A patent/CS219391A3/cs unknown
- 1991-07-16 YU YU124391A patent/YU124391A/sh unknown
- 1991-07-16 IE IE248991A patent/IE912489A1/en unknown
- 1991-07-16 BR BR919103042A patent/BR9103042A/pt not_active Application Discontinuation
- 1991-07-16 CN CN91104911A patent/CN1032000C/zh not_active Expired - Fee Related
- 1991-07-16 JP JP3175054A patent/JPH04230367A/ja not_active Withdrawn
- 1991-07-16 RU SU915001032A patent/RU2076100C1/ru active
- 1991-07-16 FI FI913431A patent/FI913431A7/fi not_active Application Discontinuation
-
1994
- 1994-02-21 AU AU55293/94A patent/AU5529394A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR9103042A (pt) | 1992-04-28 |
| KR920002548A (ko) | 1992-02-28 |
| EP0467614A1 (en) | 1992-01-22 |
| HUT58296A (en) | 1992-02-28 |
| PT98323A (pt) | 1992-06-30 |
| AU8040991A (en) | 1992-01-23 |
| FI913431A0 (fi) | 1991-07-16 |
| JPH04230367A (ja) | 1992-08-19 |
| HU912376D0 (en) | 1991-12-30 |
| CN1058209A (zh) | 1992-01-29 |
| CS219391A3 (en) | 1992-02-19 |
| CN1032000C (zh) | 1996-06-12 |
| IL98785A (en) | 1995-11-27 |
| MX9100164A (es) | 1992-02-28 |
| IL98785A0 (en) | 1992-07-15 |
| NO912772D0 (no) | 1991-07-15 |
| AU5529394A (en) | 1994-04-28 |
| NZ238912A (en) | 1992-12-23 |
| RU2076100C1 (ru) | 1997-03-27 |
| IE912489A1 (en) | 1992-01-29 |
| AU644190B2 (en) | 1993-12-02 |
| KR960005950B1 (ko) | 1996-05-06 |
| CA2046672A1 (en) | 1992-01-18 |
| YU124391A (sh) | 1994-01-20 |
| ZA915372B (en) | 1993-03-31 |
| FI913431A7 (fi) | 1992-01-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUT67434A (en) | Fluoroalkoxy-benzylamino derivatives of nitrogen containing heterocycles and pharmaceutical compositions containing them and process for their production | |
| RU94044343A (ru) | Заменители катехоламинов, пригодные в качестве бета3 -агонистов, промежуточные соединения, фармацевтические композиции, способы лечения заболеваний | |
| DK0613458T3 (da) | Acykliske ethylendiaminderivater som substans P receptorantagonister | |
| ES2168260T3 (es) | 3-aminoquinuclidinas sustituidas. | |
| DK0607164T3 (da) | Kondenserede tricykliske nitrogenholdige heterocykliske forbindelser som substans P-receptorantagonister | |
| UA27776C2 (uk) | Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців | |
| HU9303666D0 (en) | Azanorbornane derivatives | |
| CA2134964A1 (en) | Bridged Aza-Bicyclic Derivatives as Substance P Antagonists | |
| ATE166650T1 (de) | Spiroazacyclischderivate als substanz p antagonisten | |
| MY117274A (en) | Polycyclic amine compounds and their enantiomers,their method of preparation and pharmaceutical compositions in which they are present. | |
| HUP0401009A2 (hu) | 5-Hidroxitriptamin-6-ligandumokként alkalmazható 1-aril- vagy 1- alkil-szulfonilbenzazol-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
| AU9057191A (en) | N-substituted lactams useful as cholecystokinin antagonists | |
| DK0700384T3 (da) | fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin | |
| DK0450420T3 (da) | Heterocyclisk substituerede dihydropyridiner, fremgangsmåde til deres fremstilling og deres anvendelse i lægemidler | |
| DE69412103D1 (de) | Polyamidsäure-derivate mit antigastrin wirkung, ihre herstellung und ihre verwendung als arzneimittel | |
| RU94038063A (ru) | 3-фенилуреидо-азепин-2-оны и -бензазепин-2-оны, способы их получения, промежуточные соединения, фармацевтические композиции и способы лечения | |
| DK0401093T3 (da) | Hidtil ukendte pyrrolidonderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende disse | |
| KR101027556B1 (ko) | 1-페닐-2-헤테로아릴-치환된 벤즈이미다졸 유도체, 면역질환의 치료용 약제를 생산하기 위한 그의 용도 | |
| WO2016096126A1 (en) | 1-methylpyrazole-piperazine compounds having multimodal activity against pain | |
| RU92004363A (ru) | 3-арил-3(3н)хиназолиноновые антагонисты холецистокинина и фармацевтическая композиция на их основе |