NO912940L - Immunundertrykkende middel og fremgangsmaate for fremstilling av samme. - Google Patents

Immunundertrykkende middel og fremgangsmaate for fremstilling av samme.

Info

Publication number: NO912940L
Authority: NO; Norway
Prior art keywords: alkyl; immune; preparing; procedure; same
Prior art date: 1989-11-28

Application number

NO91912940A

Other languages

English (en)

Norwegian (no)

Other versions

NO912940D0 (no

Inventor

Hiroshi Nagase

Koji Kawai

Shu Matsumoto

Takashi Endoh

Yoshiaki Katsura

Kohei Arakawa

Original Assignee

Toray Industries

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-28

Filing date

1991-07-29

Publication date

1991-07-29

1991-07-29 Application filed by Toray Industries filed Critical Toray Industries

1991-07-29 Publication of NO912940D0 publication Critical patent/NO912940D0/no

1991-07-29 Publication of NO912940L publication Critical patent/NO912940L/no

Links

125000000217 alkyl group Chemical group 0.000 abstract 4
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
-1 4-5C transalkenyl Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
239000000857 delta opiate receptor antagonist Substances 0.000 abstract 1
229960003444 immunosuppressant agent Drugs 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Light Receiving Elements (AREA)
Amplifiers (AREA)

NO91912940A 1989-11-28 1991-07-29 Immunundertrykkende middel og fremgangsmaate for fremstilling av samme. NO912940L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP30849189		1989-11-28
JP32216089		1989-12-11
JP32694189		1989-12-15
PCT/JP1990/001541 WO1991007966A1 (fr)	1989-11-28	1990-11-28	Immunosuppresseur et procede de preparation d'un tel medicament

Publications (2)

Publication Number	Publication Date
NO912940D0 NO912940D0 (no)	1991-07-29
NO912940L true NO912940L (no)	1991-07-29

Family

ID=27338974

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO91912940A NO912940L (no)	1989-11-28	1991-07-29	Immunundertrykkende middel og fremgangsmaate for fremstilling av samme.

Country Status (14)

Country	Link
US (1)	US5332818A (fr)
EP (1)	EP0456833B1 (fr)
JP (1)	JP2906654B2 (fr)
KR (1)	KR940008032B1 (fr)
AT (1)	ATE119039T1 (fr)
AU (1)	AU639053B2 (fr)
CA (1)	CA2045481C (fr)
DE (1)	DE69017434T2 (fr)
DK (1)	DK0456833T3 (fr)
ES (1)	ES2069100T3 (fr)
FI (1)	FI913583A7 (fr)
GR (1)	GR3015266T3 (fr)
NO (1)	NO912940L (fr)
WO (1)	WO1991007966A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5852030A (en) *	1992-09-29	1998-12-22	Toray Industries, Inc.	Indole derivatives, process for producing the same and medicinal uses of the same
JP3605825B2 (ja) *	1992-09-29	2004-12-22	東レ株式会社	インドール誘導体，その製造方法およびその医薬用途
CA2130457A1 (fr) *	1992-12-22	1994-07-07	Hiroshi Nagase	Antitussif
US5464841A (en) *	1993-11-08	1995-11-07	Univ Minnesota	Use of delta opioid receptor antagonists to treat immunoregulatory disorders
SE9304236D0 (sv) *	1993-12-22	1993-12-22	Astra Ab	New use
SE9401727D0 (sv) *	1994-05-18	1994-05-18	Astra Ab	New compounds I
SE9401728D0 (sv) *	1994-05-18	1994-05-18	Astra Ab	New compounds II
US5578725A (en) *	1995-01-30	1996-11-26	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
US5994327A (en) *	1995-11-17	1999-11-30	Astra Ab	Process for the preparation of morphinans
ES2188888T3 (es) *	1996-01-10	2003-07-01	Glaxosmithkline Spa	Derivados morfinoides 8ii) con condensados con heterociclos.
EP0894799B1 (fr) *	1997-01-16	2004-04-07	Toray Industries, Inc.	Derives d'indolomorphinane et medicaments/remedes preventifs contre les troubles cerebraux
DE69839508D1 (de)	1997-03-31	2008-07-03	Toray Industries	Chinolinmorphinan-derivate und ihre medizinische anwendung
US6359111B1 (en)	1998-05-28	2002-03-19	Neorx Corporation	Opioid receptor targeting
US7232829B2 (en)	2001-04-06	2007-06-19	Regents Of The University Of Minnesota	Therapeutic compounds and methods
US6809104B2 (en)	2001-05-04	2004-10-26	Tularik Inc.	Fused heterocyclic compounds
WO2002089729A2 (fr)	2001-05-04	2002-11-14	Tularik Inc.	Composes heterocycliques fondus
WO2003063779A2 (fr) *	2002-01-25	2003-08-07	Regents Of The University Of Minnesota	Agents analgesiques selectifs
EP1522542A1 (fr) *	2002-07-11	2005-04-13	Toray Industries, Inc.	Agent therapeutique ou preventif pour la nausee/le vomissement
WO2004043958A1 (fr)	2002-11-06	2004-05-27	Amgen Inc.	Composes heterocycliques condenses
CA2580694A1 (fr) *	2004-09-23	2006-03-30	Alexander Michalow	Methodes permettant de reguler les systemes de neurotransmetteurs en induisant des contre-adaptations
US20080045610A1 (en) *	2004-09-23	2008-02-21	Alexander Michalow	Methods for regulating neurotransmitter systems by inducing counteradaptations
CN1298718C (zh) *	2005-03-18	2007-02-07	中国科学院上海有机化学研究所	C环连接有吡嗪环的青藤碱衍生物、合成方法及其用途
US20070185145A1 (en) *	2006-02-03	2007-08-09	Royds Robert B	Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4443605A (en) *	1982-07-30	1984-04-17	Miles Laboratories, Inc.	7β-Arylalkyl-6α, 7 α-oxymethylene-3-methoxy or 3-hydroxy-4, 5α-epoxy-17 methyl or 17-cycloalkyl-methyl morphinans
HU196376B (en) *	1985-05-23	1988-11-28	Sandoz Ag	Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds
US4816586A (en) *	1987-07-29	1989-03-28	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
US4857533A (en) *	1988-12-15	1989-08-15	Baker Cummins Pharmaceuticals, Inc.	Method of treatment for autoimmune diseases

1990
- 1990-11-27 JP JP2327453A patent/JP2906654B2/ja not_active Expired - Lifetime
- 1990-11-28 KR KR1019910700795A patent/KR940008032B1/ko not_active Expired - Fee Related
- 1990-11-28 WO PCT/JP1990/001541 patent/WO1991007966A1/fr not_active Ceased
- 1990-11-28 FI FI913583A patent/FI913583A7/fi not_active Application Discontinuation
- 1990-11-28 AU AU68768/91A patent/AU639053B2/en not_active Ceased
- 1990-11-28 CA CA002045481A patent/CA2045481C/fr not_active Expired - Fee Related
- 1990-11-28 AT AT90917694T patent/ATE119039T1/de not_active IP Right Cessation
- 1990-11-28 ES ES90917694T patent/ES2069100T3/es not_active Expired - Lifetime
- 1990-11-28 DK DK90917694.3T patent/DK0456833T3/da active
- 1990-11-28 DE DE69017434T patent/DE69017434T2/de not_active Expired - Fee Related
- 1990-11-28 EP EP90917694A patent/EP0456833B1/fr not_active Expired - Lifetime
1991
- 1991-07-29 NO NO91912940A patent/NO912940L/no unknown
1993
- 1993-03-22 US US08/034,669 patent/US5332818A/en not_active Expired - Fee Related
1995
- 1995-03-02 GR GR950400451T patent/GR3015266T3/el unknown

Also Published As

Publication number	Publication date
EP0456833B1 (fr)	1995-03-01
KR940008032B1 (ko)	1994-09-01
ATE119039T1 (de)	1995-03-15
DE69017434T2 (de)	1995-06-29
JP2906654B2 (ja)	1999-06-21
FI913583A0 (fi)	1991-07-26
NO912940D0 (no)	1991-07-29
KR920700643A (ko)	1992-08-10
DK0456833T3 (da)	1995-05-01
CA2045481C (fr)	1995-11-14
CA2045481A1 (fr)	1991-05-29
US5332818A (en)	1994-07-26
WO1991007966A1 (fr)	1991-06-13
ES2069100T3 (es)	1995-05-01
FI913583A7 (fi)	1991-07-26
AU6876891A (en)	1991-06-26
AU639053B2 (en)	1993-07-15
GR3015266T3 (en)	1995-06-30
JPH03223288A (ja)	1991-10-02
EP0456833A1 (fr)	1991-11-21
EP0456833A4 (en)	1992-03-18
DE69017434D1 (de)	1995-04-06

Publication	Publication Date	Title
NO912940D0 (no)	1991-07-29	Immunundertrykkende middel og fremgangsmaate for fremstilling av samme.
RU93004893A (ru)	1996-12-20	Производные метиленоксиндола и способ их получения
DE69003397D1 (de)	1993-10-28	Cyclische Aminverbindungen und ihre Verwendung.
NO930059L (no)	1993-01-08	O-glykosylert ifn-alfa
FI894671A0 (fi)	1989-10-03	Reglerbar faestanordning.
MX9200505A (es)	1992-08-01	2-amino-1,2,3,4-tetrahidronaftalenos y 3-aminocromanos y procedimiento para su preparacion.
HU9202199D0 (en)	1992-10-28	A new medical preparative containing benzomorphane
DK398289A (da)	1990-02-17	Anvendelse af 2-amino-4-morpholino-6-propyl-1,3,5-triaziner til fremstilling af et laegemiddel mod aeldning og demens
NO903275L (no)	1991-01-25	Fremgangsmaate for fremstilling av kromanderivater.
DE3688917D1 (de)	1993-09-30	Derivate eines Aminoketons.
DK571786A (da)	1987-05-28	Cephalosporinderivater, fremgangsmaader til fremstilling heraf samt farmaceutiske midler med indhold heraf
ATE79371T1 (de)	1992-08-15	Derivate des cysteins, verfahren zur herstellung und verwendung davon.
NO913096L (no)	1992-02-10	Fremgangsmaate for fremstilling av formlegemer av silisiuminnfiltrert silisiumkarbid.
DE69019610D1 (de)	1995-06-29	Cyclische Derivate des Amidinylthiocarbapenems.
FI925412A7 (fi)	1992-11-27	Laktoneista johdettujen 2,2-dialkoksi-syklisten ortoestereiden valmist us
IT8919814A0 (it)	1989-03-20	Dispositivo di bloccaggio e regolazione, particolarmente per compassi da disegnatore.
KR900009187A (ko)	1990-07-02	고인성 탄화규소질 소결체의 제조방법
IT8820273A0 (it)	1988-04-21	Procedimento di preparazione della n,n'_bis_(2_idrossietil)_piperazina .
IT1218776B (it)	1990-04-19	Compasso per capisaldi planoaltimetrici di poligonale, per gallerie o canalizzazioni, e suo metodo d'uso
IT9040011A0 (it)	1990-01-19	Fresa per uso dentale.
IT9041649A0 (it)	1990-07-06	Protettore della cornea e metodo per il suo ottenimento.
IT227568Y1 (it)	1997-12-15	Strumento misuratore per uso ortodontico.
MX9203485A (es)	1992-07-01	Derivados de tieno sulfonamida, composiciones farmaceuticas y uso.
FI891160A7 (fi)	1990-09-11	En ny molekylstruktur och ett foerfarande foer tillverkning av den.
KR900010235U (ko)	1990-06-02	자물쇠의 괘, 해정장치