NO914005L - Fremgangsmaate for fremstilling av vitamin d2-forbindelser og de tilsvarende alfa-hydroksylerte derivater - Google Patents

Fremgangsmaate for fremstilling av vitamin d2-forbindelser og de tilsvarende alfa-hydroksylerte derivater

Info

Publication number: NO914005L
Authority: NO; Norway
Prior art keywords: vitamin; compounds; alfa; procedure; preparation
Prior art date: 1990-02-14

Application number

NO91914005A

Other languages

English (en)

Other versions

NO914005D0 (no

NO180537C (no

NO180537B (no

Inventor

Hector Floyd Deluca

Heinrich Konstantine Schnoes

Shigeya Okada

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-14

Filing date

1991-10-11

Publication date

1992-02-05

1990-02-14 Priority claimed from US07/481,990 external-priority patent/US5030772A/en

1991-10-11 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1991-10-11 Publication of NO914005D0 publication Critical patent/NO914005D0/no

1992-02-05 Publication of NO914005L publication Critical patent/NO914005L/no

1997-01-27 Publication of NO180537B publication Critical patent/NO180537B/no

1997-05-07 Publication of NO180537C publication Critical patent/NO180537C/no

Links

MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 abstract 2
150000003703 vitamin D2 derivatives Chemical class 0.000 abstract 2
KJKIIUAXZGLUND-ICCVIKJNSA-N 25-hydroxyvitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](\C=C\[C@H](C)C(C)(C)O)C)=C\C=C1\C[C@@H](O)CCC1=C KJKIIUAXZGLUND-ICCVIKJNSA-N 0.000 abstract 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229960002061 ergocalciferol Drugs 0.000 abstract 1
BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
235000001892 vitamin D2 Nutrition 0.000 abstract 1
239000011653 vitamin D2 Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

NO914005A 1990-02-14 1991-10-11 Fremgangsmåte for fremstilling av vitamin D2-forbindelser og de tilsvarende <alfa>-hydroksylerte derivater NO180537C (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US48198590A	1990-02-14	1990-02-14
US48198890A	1990-02-14	1990-02-14
US07/481,990 US5030772A (en)	1990-02-14	1990-02-14	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
PCT/US1991/000977 WO1991012240A1 (en)	1990-02-14	1991-02-13	Process for preparing vitamin d2 compounds and the corresponding 1 alpha-hydroxylated derivatives

Publications (4)

Publication Number	Publication Date
NO914005D0 NO914005D0 (no)	1991-10-11
NO914005L true NO914005L (no)	1992-02-05
NO180537B NO180537B (no)	1997-01-27
NO180537C NO180537C (no)	1997-05-07

Family

ID=27413593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO914005A NO180537C (no)	1990-02-14	1991-10-11	Fremgangsmåte for fremstilling av vitamin D2-forbindelser og de tilsvarende <alfa>-hydroksylerte derivater

Country Status (11)

Country	Link
EP (1)	EP0468037B1 (no)
KR (1)	KR920701146A (no)
AT (1)	ATE120187T1 (no)
AU (1)	AU7307791A (no)
DE (1)	DE69108319T2 (no)
HU (1)	HUT61000A (no)
IE (1)	IE71207B1 (no)
IL (1)	IL97163A (no)
IN (2)	IN171449B (no)
NO (1)	NO180537C (no)
WO (1)	WO1991012240A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU700668B2 (en) *	1994-07-18	1999-01-14	Bone Care International, Inc.	Synthesis of 1alpha-hydroxy vitamin D
CN102131773B (zh)	2008-07-22	2014-09-24	Azad药物成分股份公司	生产帕立骨化醇的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4448721A (en) *	1982-09-20	1984-05-15	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 compounds and process for preparing same
DE3490215C2 (no) *	1983-05-09	1991-07-25	Wisconsin Alumni Res Found
US4769181A (en) *	1983-11-07	1988-09-06	Wisconsin Alumni Research Foundation	1,25-dihydroxyvitamin D2 compounds
DE3590080C2 (no) *	1984-03-05	1992-08-06	Wisconsin Alumni Research Foundation, Madison, Wis., Us
JPS63196556A (ja) *	1987-02-10	1988-08-15	Taisho Pharmaceut Co Ltd	含フツ素ビタミンｄ誘導体
JP2608322B2 (ja) *	1988-04-11	1997-05-07	日清製粉株式会社	１α，２５‐ジヒドロキシビタミンＤ▲下２▼類の製造法

1990
- 1990-07-02 IN IN549/CAL/90A patent/IN171449B/en unknown
- 1990-07-02 IN IN550/CAL/90A patent/IN171426B/en unknown
1991
- 1991-02-06 IL IL9716391A patent/IL97163A/en not_active IP Right Cessation
- 1991-02-13 KR KR1019910701330A patent/KR920701146A/ko not_active Withdrawn
- 1991-02-13 AU AU73077/91A patent/AU7307791A/en not_active Abandoned
- 1991-02-13 WO PCT/US1991/000977 patent/WO1991012240A1/en not_active Ceased
- 1991-02-13 IE IE48391A patent/IE71207B1/en not_active IP Right Cessation
- 1991-02-13 DE DE69108319T patent/DE69108319T2/de not_active Expired - Lifetime
- 1991-02-13 EP EP91904713A patent/EP0468037B1/en not_active Expired - Lifetime
- 1991-02-13 HU HU913248A patent/HUT61000A/hu unknown
- 1991-02-13 AT AT91904713T patent/ATE120187T1/de active
- 1991-10-11 NO NO914005A patent/NO180537C/no unknown

Also Published As

Publication number	Publication date
EP0468037B1 (en)	1995-03-22
IE910483A1 (en)	1991-08-14
HUT61000A (en)	1992-11-30
ATE120187T1 (de)	1995-04-15
KR920701146A (ko)	1992-08-11
EP0468037A1 (en)	1992-01-29
AU7307791A (en)	1991-09-03
NO914005D0 (no)	1991-10-11
IN171449B (no)	1992-10-17
IE71207B1 (en)	1997-02-12
DE69108319D1 (de)	1995-04-27
NO180537C (no)	1997-05-07
NO180537B (no)	1997-01-27
WO1991012240A1 (en)	1991-08-22
IL97163A (en)	1994-11-11
DE69108319T2 (de)	1995-07-27
HU913248D0 (en)	1992-02-28
IN171426B (no)	1992-10-10

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