NO920438L - N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, mellomprodukter og en fremgangsmaate for fremstilling deravsamt anvendelse som medikamenter - Google Patents

N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, mellomprodukter og en fremgangsmaate for fremstilling deravsamt anvendelse som medikamenter

Info

Publication number
NO920438L
NO920438L NO92920438A NO920438A NO920438L NO 920438 L NO920438 L NO 920438L NO 92920438 A NO92920438 A NO 92920438A NO 920438 A NO920438 A NO 920438A NO 920438 L NO920438 L NO 920438L
Authority
NO
Norway
Prior art keywords
loweralkoxy
chem
aryloxylkyl
octanes
azabicyclo
Prior art date
Application number
NO92920438A
Other languages
English (en)
Other versions
NO300040B1 (no
NO920438D0 (no
Inventor
Edward J Glamowski
David M Fink
Barbara E Kurys
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO920438D0 publication Critical patent/NO920438D0/no
Publication of NO920438L publication Critical patent/NO920438L/no
Publication of NO300040B1 publication Critical patent/NO300040B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
NO920438A 1991-02-04 1992-02-03 N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, anvendelse av forbindelsene for fremstilling av et medikament og en farmasöytisk sammensetning NO300040B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65014491A 1991-02-04 1991-02-04

Publications (3)

Publication Number Publication Date
NO920438D0 NO920438D0 (no) 1992-02-03
NO920438L true NO920438L (no) 1992-08-05
NO300040B1 NO300040B1 (no) 1997-03-24

Family

ID=24607667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO920438A NO300040B1 (no) 1991-02-04 1992-02-03 N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, anvendelse av forbindelsene for fremstilling av et medikament og en farmasöytisk sammensetning

Country Status (21)

Country Link
EP (1) EP0498331B1 (no)
JP (1) JPH089613B2 (no)
KR (1) KR100222774B1 (no)
AT (1) ATE138377T1 (no)
AU (1) AU641842B2 (no)
CA (1) CA2060573C (no)
CZ (1) CZ284754B6 (no)
DE (1) DE69210849T2 (no)
DK (1) DK0498331T3 (no)
ES (1) ES2089255T3 (no)
FI (1) FI111367B (no)
GR (1) GR3020094T3 (no)
HU (2) HU217616B (no)
IE (1) IE74905B1 (no)
IL (1) IL100861A (no)
MX (1) MX9200471A (no)
NO (1) NO300040B1 (no)
NZ (1) NZ241481A (no)
PL (1) PL169092B1 (no)
RU (1) RU2075479C1 (no)
ZA (1) ZA92753B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9510459D0 (en) * 1995-05-24 1995-07-19 Zeneca Ltd Bicyclic amines
ATE362931T1 (de) * 1995-10-13 2007-06-15 Neurosearch As 8-azabicyclo(3.2.1)oct-2en-derivate, deren herstellung und anwendung
WO1997043286A1 (en) * 1996-05-13 1997-11-20 Zeneca Limited Bicyclic amines as insecticides
GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
WO1998025924A1 (en) 1996-11-26 1998-06-18 Zeneca Limited 8-azabicyclo[3.2.1]octane-, 8-azabicyclo[3.2.1]oct-6-ene-, 9-azabicyclo[3.3.1]nonane-, 9-aza-3-oxabicyclo[3.3.1]nonane- and 9-aza-3-thiabicyclo[3.3.1]nonane derivatives, their preparation and their use as insecticides
GB9624611D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Bicyclic amine compounds
IL123716A (en) * 1997-03-27 2001-03-19 Akzo Nobel Nv Therapeutic combinations of mirtazapine and an antipsychotic agent
CA2289574C (en) 1997-05-30 2007-04-24 Neurosearch A/S 8-azabicyclo(3,2,1)oct-2-ene and octane derivatives as cholinergic ligands at nicotinic ach receptors
UA58476C2 (uk) * 1997-10-09 2003-08-15 Санофі-Сентелябо Похідні 8-азабіцикло[3.2.1]октан-3-метанаміну, фармацевтична композиція та лікарський засіб
US6251893B1 (en) * 1998-06-15 2001-06-26 Nps Allelix Corp. Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
AU1930901A (en) * 1999-12-20 2001-07-03 Eli Lilly And Company Azabicyclo(3.2.1)octane derivatives
US6835733B2 (en) 1999-12-20 2004-12-28 Eli Lilly And Company Tropane linked benzofuran derivatives
IL157412A0 (en) * 2001-02-16 2004-03-28 Aventis Pharmaceuticals Inc Av Novel heterocyclic amide derivatives and their use as dopamine d3 receptor ligands
JP2006517568A (ja) * 2003-02-12 2006-07-27 ニューロサーチ、アクティーゼルスカブ 8−アザ−ビシクロ[3.2.1]オクタン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害薬として使用する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2548666A1 (fr) * 1983-07-08 1985-01-11 Delalande Sa Nouveaux derives du nor-tropane et du granatane, leur procede de preparation et leur application en therapeutique
EP0315390B1 (en) * 1987-11-04 1994-07-20 Beecham Group Plc Novel 4-oxobenzotriazines and 4-oxoquinazolines

Also Published As

Publication number Publication date
HU9203977D0 (en) 1993-04-28
ES2089255T3 (es) 1996-10-01
JPH0559049A (ja) 1993-03-09
CS29792A3 (en) 1992-08-12
HUT60494A (en) 1992-09-28
IL100861A0 (en) 1992-11-15
DE69210849T2 (de) 1996-12-05
JPH089613B2 (ja) 1996-01-31
PL169092B1 (pl) 1996-05-31
NZ241481A (en) 1994-06-27
FI920435A0 (fi) 1992-01-31
KR920016452A (ko) 1992-09-24
FI111367B (fi) 2003-07-15
PL293363A1 (en) 1993-03-08
GR3020094T3 (en) 1996-08-31
ATE138377T1 (de) 1996-06-15
CA2060573C (en) 2002-08-13
DE69210849D1 (de) 1996-06-27
AU641842B2 (en) 1993-09-30
CZ284754B6 (cs) 1999-02-17
IE74905B1 (en) 1997-08-13
EP0498331B1 (en) 1996-05-22
CA2060573A1 (en) 1992-08-05
HU207863B (en) 1993-06-28
IL100861A (en) 1997-02-18
HU217616B (hu) 2000-03-28
ZA92753B (en) 1992-10-28
DK0498331T3 (da) 1996-09-09
HUT62295A (en) 1993-04-28
RU2075479C1 (ru) 1997-03-20
KR100222774B1 (ko) 1999-10-01
IE920349A1 (en) 1992-08-12
NO300040B1 (no) 1997-03-24
EP0498331A1 (en) 1992-08-12
HU9200321D0 (en) 1992-04-28
MX9200471A (es) 1992-08-01
AU1060592A (en) 1992-08-06
NO920438D0 (no) 1992-02-03
FI920435A7 (fi) 1992-08-05

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