NO921697L - Human-t-celle-reaktivt felint protein (trfp) isolert fra husstoev, samt anvendelse derav - Google Patents

Human-t-celle-reaktivt felint protein (trfp) isolert fra husstoev, samt anvendelse derav

Info

Publication number
NO921697L
NO921697L NO92921697A NO921697A NO921697L NO 921697 L NO921697 L NO 921697L NO 92921697 A NO92921697 A NO 92921697A NO 921697 A NO921697 A NO 921697A NO 921697 L NO921697 L NO 921697L
Authority
NO
Norway
Prior art keywords
trfp
protein
isolated
human
felint
Prior art date
Application number
NO92921697A
Other languages
English (en)
Other versions
NO921697D0 (no
Inventor
Malcolm L Gefter
Richard D Garman
Julia L Greenstein
Mei-Chang Kuo
Bruce L Rogers
Andrew W Brauer
Irwin J Griffith
Jay Morgenstern
Julian Bond
Original Assignee
Immulogic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharma Corp filed Critical Immulogic Pharma Corp
Publication of NO921697D0 publication Critical patent/NO921697D0/no
Publication of NO921697L publication Critical patent/NO921697L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)

Abstract

I hovedsak rent, kovalent bundet humant T-celle- reaktivt felint protein (TRFPJ med omtrent 40.000 MW har blitt isolert fra støvsugerpose- ekstrakt erholdt ved affinitetsrensing av hus*-støv samlet opp fra flere hus med katter; DNA som koder for alt eller en del av TRFP eller peptidet; blandinger inneholdende et slikt protein eller peptid eller deler derav samt antistoff som er reaktive mot TRFP eller peptidet er beskrevet. Det er også beskrevet rekombinant TRFP eller peptic; -modifisert eller imitert TRFP peptider samt dere bruk for diagnostiske eller terapeutiske formål.
NO92921697A 1989-11-03 1992-04-30 Human-t-celle-reaktivt felint protein (trfp) isolert fra husstoev, samt anvendelse derav NO921697L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43156589A 1989-11-03 1989-11-03
PCT/US1990/006548 WO1991006571A1 (en) 1989-11-03 1990-11-02 A human t cell reactive feline protein (trfp) isolated from house dust and uses therefor

Publications (2)

Publication Number Publication Date
NO921697D0 NO921697D0 (no) 1992-04-30
NO921697L true NO921697L (no) 1992-07-03

Family

ID=23712496

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92921697A NO921697L (no) 1989-11-03 1992-04-30 Human-t-celle-reaktivt felint protein (trfp) isolert fra husstoev, samt anvendelse derav

Country Status (11)

Country Link
EP (1) EP0500785B1 (no)
JP (1) JP3251012B2 (no)
AT (1) ATE216401T1 (no)
AU (1) AU650249B2 (no)
CA (1) CA2073045C (no)
DE (1) DE69033949T2 (no)
DK (1) DK0500785T3 (no)
ES (1) ES2174822T3 (no)
FI (1) FI921979A0 (no)
NO (1) NO921697L (no)
WO (1) WO1991006571A1 (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547669A (en) * 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
US5328991A (en) * 1989-11-03 1994-07-12 Immulogic Pharmaceutical Corp. Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes
US6120769A (en) * 1989-11-03 2000-09-19 Immulogic Pharmaceutical Corporation Human T cell reactive feline protein (TRFP) isolated from house dust and uses therefor
US6019972A (en) * 1989-11-03 2000-02-01 Immulogic Pharmaceutical Corporation Peptides of human T cell reactive feline protein (TRFP)
JP4246794B2 (ja) * 1991-10-16 2009-04-02 メルク パテント ゲーエムベーハー レコンビトープペプチド
US7288256B1 (en) 1991-10-16 2007-10-30 Merck Patent Gmbh T cell epitopes of the major allergens from dermatophagoides (house dust mite)
JPH07502890A (ja) * 1991-10-16 1995-03-30 イミユロジク・フアーマシユーチカル・コーポレーシヨン ダーマトファゴイデス（Ｄｅｒｍａｔｏｐｈａｇｏｉｄｅｓ）（家ほこりダニ）からの主要なアレルゲンのＴ細胞エピトープ
IL105153A (en) * 1992-03-25 1999-12-22 Immulogic Pharma Corp Therapeutic compositions comprising peptides derived from human t cell reactive feline protein
US5820862A (en) * 1994-04-14 1998-10-13 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
DE69733343D1 (de) 1996-03-21 2005-06-30 Circassia Ltd Kryptische peptide und verfahren zu ihrer identifizierung
DE19713001A1 (de) * 1997-03-27 1998-10-01 Merck Patent Gmbh Graminaenpollenallergenmutanten zur spezifischen Immuntherapie, deren Herstellung und Verwendung
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US7879977B2 (en) 1998-01-31 2011-02-01 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
ATE430199T1 (de) 1998-01-31 2009-05-15 Univ Arkansas Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie
GB9930616D0 (en) 1999-12-24 2000-02-16 Mathilda & Terence Kennedy Ins Activation and inhibition of the immune system
EP1272213B1 (en) 2000-04-06 2006-03-08 SEER Pharmaceuticals, LLC. Microbial delivery system
US8246945B2 (en) 2000-04-06 2012-08-21 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
AU2002216245A1 (en) 2000-12-22 2002-07-08 Synovis Limited Methods of modulating toll-related receptor (trr) signaling
US20070248584A1 (en) 2003-06-10 2007-10-25 The University Of Melbourne Immunomodulating Compositions, Uses Therefore and Processes for Their Production
WO2005037293A1 (en) 2003-10-16 2005-04-28 Univ Monash Immunomodulating compositions and uses therefor
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
CA2702340C (en) 2006-10-12 2014-12-16 The University Of Queensland Compositions and methods for modulating immune responses
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
EA023303B1 (ru) 2007-08-15 2016-05-31 Сиркейшиа Лимитед Пептидная композиция для формирования толерантности к клещам домашней пыли и ее применение
WO2009079712A1 (en) 2007-12-24 2009-07-02 The University Of Queensland Coating method
WO2009097660A1 (en) 2008-02-07 2009-08-13 The University Of Queensland Patch production
CA2760680A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection by microneedle patch with analyte selective reagents
GB0821806D0 (en) * 2008-11-28 2009-01-07 Circassia Ltd Compositions with reduced dimer formation
CN102325563A (zh) 2008-12-22 2012-01-18 昆士兰大学 贴剂制备
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
EP2635596B8 (en) 2010-11-01 2020-03-11 University of Technology Sydney Immune-modulating agents and uses therefor
US8609621B2 (en) 2010-11-15 2013-12-17 E I Du Pont De Nemours And Company Acid-cleavable linkers exhibiting altered rates of acid hydrolysis
EP2765927B1 (en) 2011-10-12 2021-02-24 Vaxxas Pty Limited Delivery device
US11147954B2 (en) 2015-02-02 2021-10-19 Vaxxas Pty Limited Microprojection array applicator and method
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
US20180264244A1 (en) 2015-09-28 2018-09-20 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
AU2018241251B2 (en) 2017-03-31 2024-06-27 Vaxxas Pty Limited Device and method for coating surfaces
EP3639010B1 (en) 2017-06-13 2025-08-06 Vaxxas Pty Limited Quality control of substrate coatings
EP4548954A3 (en) 2017-08-04 2025-07-30 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
CN117069865B (zh) * 2023-10-12 2024-03-01 中国农业科学院饲料研究所 一种基于T细胞抗原表位猫过敏原蛋白嵌合肽cFel d 1的原核表达及其卵黄抗体的制备

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Also Published As

Publication number Publication date
CA2073045A1 (en) 1991-05-04
EP0500785B1 (en) 2002-04-17
AU6733090A (en) 1991-05-31
FI921979A7 (fi) 1992-04-30
NO921697D0 (no) 1992-04-30
WO1991006571A1 (en) 1991-05-16
EP0500785A1 (en) 1992-09-02
JP3251012B2 (ja) 2002-01-28
FI921979L (fi) 1992-04-30
AU650249B2 (en) 1994-06-16
CA2073045C (en) 2007-05-22
FI921979A0 (fi) 1992-04-30
JPH05502445A (ja) 1993-04-28
DE69033949T2 (de) 2002-11-14
DE69033949D1 (de) 2002-05-23
ATE216401T1 (de) 2002-05-15
ES2174822T3 (es) 2002-11-16
DK0500785T3 (da) 2002-08-19

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