NO922273L - Tioxantenon-antitumormidler - Google Patents

Tioxantenon-antitumormidler

Info

Publication number: NO922273L
Authority: NO; Norway
Prior art keywords: alkyl; hydrogen; ch2n; thioxanthenones; antitumor agents
Prior art date: 1991-06-10

Application number

NO92922273A

Other languages

English (en)

Other versions

NO922273D0 (no

NO302364B1 (no

Inventor

Theodore Charles Miller

Joseph Charles Collins

Kenneth Charles Mattes

Robert Bruno Perni

Thomas Hughes Corbett

Mark Philip Wentland

Original Assignee

Sterling Winthrop Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-10

Filing date

1992-06-10

Publication date

1992-12-11

1992-06-10 Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc

1992-06-10 Publication of NO922273D0 publication Critical patent/NO922273D0/no

1992-12-11 Publication of NO922273L publication Critical patent/NO922273L/no

1998-02-23 Publication of NO302364B1 publication Critical patent/NO302364B1/no

Links

239000002246 antineoplastic agent Substances 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000004005 formimidoyl group Chemical group [H]\N=C(/[H])* 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
206010028980 Neoplasm Diseases 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
241000124008 Mammalia Species 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
125000004663 dialkyl amino group Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
- C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/14—Thioxanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D335/16—Oxygen atoms, e.g. thioxanthones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO922273A 1991-06-10 1992-06-10 Tioksantenon-forbindelser, farmasöytisk preparat inneholdende slike og deres anvendelse NO302364B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71317391A	1991-06-10	1991-06-10
US83515992A	1992-02-13	1992-02-13

Publications (3)

Publication Number	Publication Date
NO922273D0 NO922273D0 (no)	1992-06-10
NO922273L true NO922273L (no)	1992-12-11
NO302364B1 NO302364B1 (no)	1998-02-23

Family

ID=27108950

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO922273A NO302364B1 (no)	1991-06-10	1992-06-10	Tioksantenon-forbindelser, farmasöytisk preparat inneholdende slike og deres anvendelse

Country Status (20)

Country	Link
EP (1)	EP0518414B1 (no)
JP (1)	JP3045354B2 (no)
KR (1)	KR100209826B1 (no)
AT (1)	ATE106882T1 (no)
AU (1)	AU642596B2 (no)
CA (1)	CA2070120C (no)
DE (1)	DE69200179T2 (no)
DK (1)	DK0518414T3 (no)
ES (1)	ES2055635T3 (no)
FI (1)	FI114024B (no)
HU (1)	HU218655B (no)
IE (1)	IE66828B1 (no)
IL (1)	IL102139A (no)
MX (1)	MX9202753A (no)
NO (1)	NO302364B1 (no)
NZ (1)	NZ242862A (no)
PH (1)	PH30883A (no)
RU (1)	RU2075477C1 (no)
SG (1)	SG50625A1 (no)
TW (1)	TW218015B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5091410A (en) *	1991-06-10	1992-02-25	Sterling Winthrop Inc.	Thioxanthenone antitumor agents
US5346917A (en) *	1991-06-10	1994-09-13	Sterling Winthrop Inc.	Thioxanthenone antitumor agents
US5665760A (en) *	1995-09-18	1997-09-09	Sanofi Winthrop, Inc.	Lyophilized thioxanthenone antitumor agents
CA2695203A1 (en) *	2007-07-31	2009-02-05	University Of North Dakota Research Foundation	Improved method for the synthesis of substituted formylamines and substituted amines
FR2979823B1 (fr) *	2011-09-13	2013-09-27	Pf Medicament	Utilisation du 3-(r)-[3-(2-methoxyphenylthio)-2-(s)-methyl-propyl]amino-3,4-dihydro-2h-1,5-benzoxathiepine pour le traitement du cancer et en particulier pour la prevention et/ou le traitement des metastases cancereuses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3745172A (en) *	1970-10-05	1973-07-10	Sterling Drug Inc	1-(di-(lower-alkyl)aminoalkylamino)-9-oxothioxanthenes
US4539412A (en) *	1982-07-08	1985-09-03	Rensselaer Polytechnic Institute	7-Hydroxylucanthone, 7-hydroxhycanthone and their analogs
US5091410A (en) *	1991-06-10	1992-02-25	Sterling Winthrop Inc.	Thioxanthenone antitumor agents

1992
- 1992-05-21 AU AU17046/92A patent/AU642596B2/en not_active Ceased
- 1992-05-22 NZ NZ242862A patent/NZ242862A/xx not_active IP Right Cessation
- 1992-06-01 CA CA002070120A patent/CA2070120C/en not_active Expired - Fee Related
- 1992-06-03 DK DK92201587.0T patent/DK0518414T3/da active
- 1992-06-03 ES ES92201587T patent/ES2055635T3/es not_active Expired - Lifetime
- 1992-06-03 TW TW081104387A patent/TW218015B/zh active
- 1992-06-03 SG SG1996007125A patent/SG50625A1/en unknown
- 1992-06-03 DE DE69200179T patent/DE69200179T2/de not_active Expired - Fee Related
- 1992-06-03 AT AT92201587T patent/ATE106882T1/de not_active IP Right Cessation
- 1992-06-03 EP EP92201587A patent/EP0518414B1/en not_active Expired - Lifetime
- 1992-06-08 JP JP4147101A patent/JP3045354B2/ja not_active Expired - Fee Related
- 1992-06-09 MX MX9202753A patent/MX9202753A/es not_active IP Right Cessation
- 1992-06-09 RU SU925052026A patent/RU2075477C1/ru not_active IP Right Cessation
- 1992-06-09 KR KR1019920009956A patent/KR100209826B1/ko not_active Expired - Fee Related
- 1992-06-09 IL IL102139A patent/IL102139A/xx not_active IP Right Cessation
- 1992-06-10 PH PH44488A patent/PH30883A/en unknown
- 1992-06-10 FI FI922694A patent/FI114024B/fi not_active IP Right Cessation
- 1992-06-10 HU HU9201926A patent/HU218655B/hu not_active IP Right Cessation
- 1992-06-10 NO NO922273A patent/NO302364B1/no unknown
- 1992-07-01 IE IE921871A patent/IE66828B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH05178853A (ja)	1993-07-20
PH30883A (en)	1997-12-23
FI114024B (fi)	2004-07-30
NO922273D0 (no)	1992-06-10
AU642596B2 (en)	1993-10-21
CA2070120A1 (en)	1992-12-11
DE69200179T2 (de)	1995-01-19
DE69200179D1 (de)	1994-07-14
KR930000499A (ko)	1993-01-15
CA2070120C (en)	2005-11-15
HU218655B (hu)	2000-10-28
FI922694L (fi)	1992-12-11
NZ242862A (en)	1993-09-27
RU2075477C1 (ru)	1997-03-20
FI922694A0 (fi)	1992-06-10
SG50625A1 (en)	1998-07-20
ATE106882T1 (de)	1994-06-15
EP0518414B1 (en)	1994-06-08
IE921871A1 (en)	1992-12-16
IL102139A0 (en)	1993-01-14
IE66828B1 (en)	1996-02-07
NO302364B1 (no)	1998-02-23
DK0518414T3 (da)	1994-08-15
KR100209826B1 (ko)	1999-07-15
AU1704692A (en)	1992-12-17
JP3045354B2 (ja)	2000-05-29
IL102139A (en)	1997-03-18
TW218015B (no)	1993-12-21
ES2055635T3 (es)	1994-08-16
EP0518414A1 (en)	1992-12-16
HU9201926D0 (en)	1992-08-28
HUT61992A (en)	1993-03-29
MX9202753A (es)	1993-01-01

Publication	Publication Date	Title
TW349097B (en)	1999-01-01	Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
DK0870768T3 (da)	2002-07-01	Azaindol-ethylaminderivater som nikotinacetylcholinreceptor-bindingsmidler
TW360652B (en)	1999-06-11	Acryloyl substituted disstamycin derivatives, process for preparing them, and pharmaceutical composition comprising them
ES513420A0 (es)	1983-04-01	"procedimiento para preparar derivados de 2-oxoazetidina".
IL109241A0 (en)	1994-07-31	Thioxanthenone derivatives and pharmaceutical compositions containing them
NO922273D0 (no)	1992-06-10	Tioxantenon-antitumormidler
NZ225022A (en)	1990-07-26	Substituted ergoline derivatives and pharmaceutical compositions
FI940011A0 (fi)	1994-01-03	Mono- ja bis-alkyyliaminoantrasykliinit
ATE225789T1 (de)	2002-10-15	Loracarbef hydrochlorid c1-c3 alkohol-solvate und deren verwendungen