NO923533L - Nye 5-amino-4-hydroksyheksansyrederivater som terapeutika - Google Patents

Nye 5-amino-4-hydroksyheksansyrederivater som terapeutika

Info

Publication number: NO923533L
Authority: NO; Norway
Prior art keywords: terminally; group; bonded; sulfo; amino acid
Prior art date: 1991-09-12

Application number

NO92923533A

Other languages

English (en)

Norwegian (no)

Other versions

NO923533D0 (no

Inventor

Marc Lang

Guido Bold

Alexander Faessler

Peter Schneider

Peter Van Hoogevest

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-12

Filing date

1992-09-11

Publication date

1993-03-15

1992-09-11 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1992-09-11 Publication of NO923533D0 publication Critical patent/NO923533D0/no

1993-03-15 Publication of NO923533L publication Critical patent/NO923533L/no

Links

239000002253 acid Substances 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
150000001371 alpha-amino acids Chemical class 0.000 abstract 2
235000008206 alpha-amino acids Nutrition 0.000 abstract 2
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
208000030507 AIDS Diseases 0.000 abstract 1
108010016626 Dipeptides Proteins 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000006517 heterocyclyl carbonyl group Chemical group 0.000 abstract 1
239000004030 hiv protease inhibitor Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000005505 thiomorpholino group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Virology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Crystallography & Structural Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO92923533A 1991-09-12 1992-09-11 Nye 5-amino-4-hydroksyheksansyrederivater som terapeutika NO923533L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CH268991		1991-09-12
CH98092		1992-03-27
CH200792		1992-06-25

Publications (2)

Publication Number	Publication Date
NO923533D0 NO923533D0 (no)	1992-09-11
NO923533L true NO923533L (no)	1993-03-15

Family

ID=27172572

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO92923533A NO923533L (no)	1991-09-12	1992-09-11	Nye 5-amino-4-hydroksyheksansyrederivater som terapeutika

Country Status (15)

Country	Link
EP (1)	EP0532466A3 (pl)
JP (1)	JPH05230095A (pl)
KR (1)	KR930006050A (pl)
AU (1)	AU661018B2 (pl)
CA (1)	CA2077948A1 (pl)
CZ (1)	CZ280292A3 (pl)
FI (1)	FI924035A7 (pl)
HU (1)	HUT63632A (pl)
IL (1)	IL103126A (pl)
MX (1)	MX9205208A (pl)
NO (1)	NO923533L (pl)
NZ (1)	NZ244288A (pl)
PL (1)	PL169969B1 (pl)
RU (1)	RU2067585C1 (pl)
SK (1)	SK280292A3 (pl)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5643878A (en) *	1991-09-12	1997-07-01	Ciba-Geigy Corporation	5-amino-4-hydroxyhexanoic acid derivatives
US5888992A (en) *	1992-03-11	1999-03-30	Narhex Limited	Polar substituted hydrocarbons
MXPA93002392A (es)	1992-03-11	2005-02-04	Narhex Ltd	Derivados amino de hidrocarburos-oxo e hidroxi-substituidos.
JPH07504654A (ja) *	1992-03-11	1995-05-25	ナルヘックス　リミテッド	オキソ及びヒドロキシ置換炭化水素のアミン誘導体
US6071895A (en)	1992-03-11	2000-06-06	Narhex Limited	Polar-substituted hydrocarbons
TW217410B (pl) *	1992-04-01	1993-12-11	Ciba Geigy
DE59303870D1 (de)	1992-12-23	1996-10-24	Ciba Geigy Ag	Antiretrovirale hydrazinderivate
EP0618222A3 (en) *	1993-03-11	1997-01-02	Ciba Geigy Ag	Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid.
EP0626178A1 (de) *	1993-05-17	1994-11-30	Ciba-Geigy Ag	Verwendung von Hemmstoffen von HIV-Aspartatproteasen zur Bekämpfung von Tumorerkrankungen
IL110898A0 (en) *	1993-09-10	1994-11-28	Narhex Australia Pty Ltd	Polar-substituted hydrocarbons
IL110752A (en) *	1993-09-13	2000-07-26	Abbott Lab	Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) *	1993-10-01	1996-09-24	Abbott Laboratories	Pharmaceutical composition
IL111991A (en) *	1994-01-28	2000-07-26	Abbott Lab	Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
AU4117396A (en) *	1994-11-29	1996-06-19	Novartis Ag	Morpholinoethylamide derivatives
US6037157A (en)	1995-06-29	2000-03-14	Abbott Laboratories	Method for improving pharmacokinetics
US5817757A (en) *	1995-10-30	1998-10-06	Merck & Co., Inc.	Inhibitors of peptide binding to MHO class II proteins
AU7475396A (en) *	1995-10-30	1997-05-22	Merck & Co., Inc.	Novel inhibitors of peptide binding to mhc class ii proteins
US5840835A (en) *	1995-10-30	1998-11-24	Merck & Co., Inc.	Inhibitors of peptide binding to MHC class II proteins
US5914332A (en)	1995-12-13	1999-06-22	Abbott Laboratories	Retroviral protease inhibiting compounds
US6232333B1 (en)	1996-11-21	2001-05-15	Abbott Laboratories	Pharmaceutical composition
CN1343219A (zh) *	1999-01-28	2002-04-03	中外制药株式会社	取代的苯乙基胺衍生物
US6455734B1 (en) *	2000-08-09	2002-09-24	Magnesium Diagnostics, Inc.	Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
KR100708221B1 (ko)	1999-08-31	2007-04-17	아지노모토 가부시키가이샤	에폭사이드 결정의 제조방법
TR201809435T4 (tr)	2000-01-19	2018-07-23	Abbvie Inc	Geliştirilmiş farmasötik formülasyonlar.
US6506786B2 (en)	2001-02-13	2003-01-14	Pharmacor Inc.	HIV protease inhibitors based on amino acid derivatives
EA009943B1 (ru) *	2002-11-01	2008-04-28	Вирофарма Инкорпорейтед	Соединения бензофурана, композиции и способы лечения и профилактики инфекций, вызванных вирусом гепатита с, и связанных с ним заболеваний
US7388008B2 (en)	2004-08-02	2008-06-17	Ambrilia Biopharma Inc.	Lysine based compounds
ES2452718T3 (es)	2005-11-30	2014-04-02	Taimed Biologics, Inc.	Profármacos a base de lisina de inhibidores de la aspartil proteasa y procesos para su preparación
BRPI0707302B8 (pt)	2006-01-27	2021-05-25	Fibrogen Inc	compostos de cianoisoquinolina que atuam no dano tecidual associado com isquemia, hipóxia e anemia, bem como composição farmacêutica que os compreende
BRPI0710527B8 (pt)	2006-04-04	2021-05-25	Fibrogen Inc	compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende
CA2664118A1 (en)	2006-09-21	2008-07-03	Ambrilia Biopharma Inc.	Protease inhibitors
JP5649584B2 (ja)	2008-11-14	2015-01-07	フィブロジェンインコーポレイテッド	Ｈｉｆヒドロキシラーゼ阻害剤としてのチオクロメン誘導体
AU2014209319B2 (en)	2013-01-24	2018-04-19	Fibrogen, Inc.	Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid
CN115466316A (zh) *	2021-06-10	2022-12-13	首都医科大学	抑制迁移的1-咪唑-β-咔啉-3-甲酰-RGDF及制备,抗癌转移作用和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5126326A (en) *	1989-06-06	1992-06-30	Bio-Mega, Inc.	Enzyme inhibiting peptide derivatives

1992
- 1992-09-03 EP EP19920810678 patent/EP0532466A3/de not_active Ceased
- 1992-09-07 JP JP4238424A patent/JPH05230095A/ja active Pending
- 1992-09-09 KR KR1019920016530A patent/KR930006050A/ko not_active Withdrawn
- 1992-09-09 FI FI924035A patent/FI924035A7/fi not_active Application Discontinuation
- 1992-09-10 AU AU22889/92A patent/AU661018B2/en not_active Ceased
- 1992-09-10 IL IL103126A patent/IL103126A/xx not_active IP Right Cessation
- 1992-09-10 CA CA002077948A patent/CA2077948A1/en not_active Abandoned
- 1992-09-10 NZ NZ244288A patent/NZ244288A/en unknown
- 1992-09-11 NO NO92923533A patent/NO923533L/no unknown
- 1992-09-11 PL PL92295905A patent/PL169969B1/pl unknown
- 1992-09-11 HU HU9202925A patent/HUT63632A/hu unknown
- 1992-09-11 CZ CS922802A patent/CZ280292A3/cs unknown
- 1992-09-11 MX MX9205208A patent/MX9205208A/es not_active IP Right Cessation
- 1992-09-11 RU SU925052915A patent/RU2067585C1/ru active
- 1992-09-11 SK SK2802-92A patent/SK280292A3/sk unknown

Also Published As

Publication number	Publication date
AU2288992A (en)	1993-03-18
CZ280292A3 (en)	1994-01-19
CA2077948A1 (en)	1993-03-13
EP0532466A3 (en)	1993-06-16
SK280292A3 (en)	1995-02-08
AU661018B2 (en)	1995-07-13
MX9205208A (es)	1993-03-01
RU2067585C1 (ru)	1996-10-10
JPH05230095A (ja)	1993-09-07
FI924035A7 (fi)	1993-03-13
PL169969B1 (pl)	1996-09-30
KR930006050A (ko)	1993-04-20
HUT63632A (en)	1993-09-28
IL103126A (en)	1997-09-30
FI924035A0 (fi)	1992-09-09
IL103126A0 (en)	1993-02-21
PL295905A1 (en)	1993-05-17
HU9202925D0 (en)	1992-11-30
NZ244288A (en)	1995-03-28
EP0532466A2 (de)	1993-03-17
NO923533D0 (no)	1992-09-11

Publication	Publication Date	Title
NO923533L (no)	1993-03-15	Nye 5-amino-4-hydroksyheksansyrederivater som terapeutika
YU66201A (sh)	2005-07-19	Derivati amina kao inhibitori proteaze
ATE326454T1 (de)	2006-06-15	Neue bernsteinsäure derivative als cysteine- protease-inhibitoren
CA2093221A1 (en)	1993-02-03	N-sulfonylindoline derivatives carrying an amide functional group, their preparation, and the pharmaceutical compositions in which they are present
DK0944617T3 (da)	2003-09-01	Krystaller af benzimidazolderivater og deres fremstilling
DK436081A (da)	1982-04-04	Substituerede acyl-derivater af 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyrer og farmaceutisk acceptable salte deraf fremgangsmaade til deres fremstilling og deres anvendelse
TW346485B (en)	1998-12-01	Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents
ES2117795T3 (es)	1998-08-16	Derivados de acetamida y su uso como modificadores del comportamiento de toma alimentaria.
AR045782A2 (es)	2005-11-16	Derivados de piperidina que tienen actividad farmaceutica
NO954975L (no)	1996-06-10	Aromatisk substituerte w-amino-alkansyreamider og alkansyrediamider
NO941675L (no)	1994-11-08	Peptid-ketoner som inhibitorer av interleukin-1beta-omdannede enzym
WO2002100833A1 (en)	2002-12-19	Rho KINASE INHIBITORS
ATE90107T1 (de)	1993-06-15	Peptide mit collagenase hemmender wirkung.
WO2004052837A3 (en)	2004-09-10	Amino substituted hydroxyphenyl benzophenone derivatives
DK142084D0 (da)	1984-02-29	N-phenyl-n'-cycloalkylalkanoyl-piperaziner og fremgangsmaade til fremstilling heraf
WO2004020430A3 (fr)	2004-04-22	Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
WO2008136444A1 (ja)	2008-11-13	縮合複素環誘導体
WO2003008379A1 (en)	2003-01-30	Azasugar compounds
SE0101579D0 (sv)	2001-05-04	New compounds
NO20060703L (no)	2006-03-13	Fremgangsmate for fremstilling av cis-4-fluor-1-prolinderivater
MY103348A (en)	1993-06-30	Heteroaryl 3-0x0-propanenitrile derivatives and process for their preparation
CO4950567A1 (es)	2000-09-01	Inhibidores de proteasas dores de proteasas.
AU2003207432A1 (en)	2003-09-02	Urea linker derivatives for use as ppar modulators
NO964698D0 (no)	1996-11-06	Bicykliske aminderivater som inhibitorer av nitrogenoksid-syntetase
EP0202062A3 (en)	1987-08-19	Quinuclidine derivatives