NO923673L - Nye nitrogencykliske ligander, fremgangsmaate for deres fremstilling, polymetallkomplekser og et diagnostisk og terapeutisk preparat - Google Patents

Nye nitrogencykliske ligander, fremgangsmaate for deres fremstilling, polymetallkomplekser og et diagnostisk og terapeutisk preparat

Info

Publication number
NO923673L
NO923673L NO92923673A NO923673A NO923673L NO 923673 L NO923673 L NO 923673L NO 92923673 A NO92923673 A NO 92923673A NO 923673 A NO923673 A NO 923673A NO 923673 L NO923673 L NO 923673L
Authority
NO
Norway
Prior art keywords
preparation
ligands
diagnostic
nitrogencyclic
polymetal
Prior art date
Application number
NO92923673A
Other languages
English (en)
Norwegian (no)
Other versions
NO923673D0 (no
Inventor
Olivier Rousseaux
Michel Schaefer
Anne Bouillot
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of NO923673D0 publication Critical patent/NO923673D0/no
Publication of NO923673L publication Critical patent/NO923673L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO92923673A 1991-01-24 1992-09-22 Nye nitrogencykliske ligander, fremgangsmaate for deres fremstilling, polymetallkomplekser og et diagnostisk og terapeutisk preparat NO923673L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9100811A FR2672051B1 (fr) 1991-01-24 1991-01-24 Nouveaux ligands macrocycliques azotes, procede de preparation, complexes polymetalliques, composition de diagnostic et therapeutique.
PCT/FR1992/000057 WO1992012978A1 (fr) 1991-01-24 1992-01-22 Nouveaux ligands macrocycliques azotes, procede de preparation, complexes polymetalliques, composition de diagnostic et therapeutique

Publications (2)

Publication Number Publication Date
NO923673D0 NO923673D0 (no) 1992-09-22
NO923673L true NO923673L (no) 1992-11-24

Family

ID=9409017

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923673A NO923673L (no) 1991-01-24 1992-09-22 Nye nitrogencykliske ligander, fremgangsmaate for deres fremstilling, polymetallkomplekser og et diagnostisk og terapeutisk preparat

Country Status (18)

Country Link
US (1) US5374416A (de)
EP (1) EP0499501B1 (de)
JP (1) JPH0735381B2 (de)
KR (1) KR960014355B1 (de)
AT (1) ATE169916T1 (de)
AU (1) AU650325B2 (de)
CA (1) CA2078983A1 (de)
CZ (1) CZ281225B6 (de)
DE (1) DE69226669T2 (de)
FR (1) FR2672051B1 (de)
HU (1) HUT70023A (de)
IE (1) IE920204A1 (de)
IL (1) IL100717A (de)
MX (1) MX9200319A (de)
NO (1) NO923673L (de)
NZ (1) NZ241356A (de)
WO (1) WO1992012978A1 (de)
ZA (1) ZA92470B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69024826T2 (de) * 1989-02-10 1996-06-27 Celltech Therapeutics Ltd Aza-Macrozyklen und Verfahren zu deren Herstellung
US5645818A (en) * 1989-03-24 1997-07-08 Guerbet S.A. Diagnostic compositions comprising a complex formed by a nitrogenous macrocyclic ligand with metal ions
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
US5462725A (en) * 1993-05-06 1995-10-31 The Dow Chemical Company 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
DE4318369C1 (de) * 1993-05-28 1995-02-09 Schering Ag Verwendung von makrocyclischen Metallkomplexen als Temperatursonden
US6693190B1 (en) 1994-05-11 2004-02-17 Bracco International B.V. Enhanced relaxivity monomeric and multimeric compounds
US20030017941A1 (en) * 1997-03-07 2003-01-23 The Procter & Gamble Company Catalysts and methods for catalytic oxidation
ES2242996T3 (es) * 1997-03-07 2005-11-16 THE PROCTER & GAMBLE COMPANY Composiciones de blanqueo.
ZA981883B (en) * 1997-03-07 1998-09-01 Univ Kansas Catalysts and methods for catalytic oxidation
US20080125344A1 (en) * 2006-11-28 2008-05-29 Daryle Hadley Busch Bleach compositions
US6565828B2 (en) 2000-04-07 2003-05-20 Bristol-Myers Squibb Company Macrocyclic chelants for metallopharmaceuticals
DE60136476D1 (de) * 2000-09-29 2008-12-18 Anormed Inc -stickstoffhaltigen zyklischen polyaminen und deren verbindungen
DE10117242C1 (de) * 2001-04-06 2002-05-16 Schering Ag Unsymmetrische dimere Metallkomplexe, Liganden für diese Metallkomplexe, Verfahren zu deren Herstellung, Arzneimittel bzw. Diagnosemittel, die die Metallkomplexe enthalten, insbesondere Kontrastmittel
DK1411918T3 (da) * 2001-07-31 2012-04-23 Genzyme Global S A R L Fremgangsmåder til at mobilisere progenitor/stamceller
US20040048763A1 (en) * 2002-08-27 2004-03-11 The Procter & Gamble Co. Bleach compositions
US20050192195A1 (en) * 2002-08-27 2005-09-01 Busch Daryle H. Catalysts and methods for catalytic oxidation
EP1637524A1 (de) * 2004-09-20 2006-03-22 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. 10-substituierte 1-, 4, 7,-tris (carboxymethyl)-1,4,7,10-tetraazacyclo-dodecanederivate zur Verwendung als Kontrastmittel
TWI429404B (zh) * 2008-03-03 2014-03-11 Senomyx Inc 異山梨醇衍生物及彼等作為風味改良劑、促味劑及促味增強劑之用途
JP5735791B2 (ja) * 2010-12-07 2015-06-17 住友化学株式会社 金属錯体を含む素子
FR2968999B1 (fr) 2010-12-20 2013-01-04 Guerbet Sa Nanoemulsion de chelate pour irm
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles
US11007283B2 (en) 2016-04-13 2021-05-18 Bracco Imaging S.P.A. Contrast agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53144592A (en) * 1977-05-19 1978-12-15 Tabuse Iwao 122alkyll1*4*7*100tetrazacyclotridecane
JP2833766B2 (ja) * 1987-07-16 1998-12-09 ニユコメド・アクシエセルカペト アミノポリカルボン酸およびその誘導体
DE3728525A1 (de) * 1987-08-24 1989-03-16 Schering Ag Mehrkernige substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
WO1990007261A2 (en) * 1988-12-22 1990-07-12 The Dow Chemical Company Process for preparing mono-n-alkylated polyazamacrocycles

Also Published As

Publication number Publication date
US5374416A (en) 1994-12-20
HU9203029D0 (en) 1992-12-28
FR2672051A1 (fr) 1992-07-31
EP0499501A3 (de) 1992-08-26
FR2672051B1 (fr) 1993-05-21
IL100717A (en) 1996-06-18
AU1256292A (en) 1992-08-27
AU650325B2 (en) 1994-06-16
CZ290992A3 (en) 1993-02-17
ATE169916T1 (de) 1998-09-15
EP0499501A2 (de) 1992-08-19
KR960014355B1 (ko) 1996-10-15
JPH0735381B2 (ja) 1995-04-19
DE69226669D1 (de) 1998-09-24
NZ241356A (en) 1995-02-24
JPH05504361A (ja) 1993-07-08
EP0499501B1 (de) 1998-08-19
IL100717A0 (en) 1992-09-06
NO923673D0 (no) 1992-09-22
CZ281225B6 (cs) 1996-07-17
DE69226669T2 (de) 1999-04-15
IE920204A1 (en) 1992-07-29
ZA92470B (en) 1993-07-23
WO1992012978A1 (fr) 1992-08-06
HUT70023A (en) 1995-09-28
MX9200319A (es) 1992-07-01
CA2078983A1 (fr) 1992-07-25

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