NO923739L - Kontrastmidler - Google Patents

Kontrastmidler

Info

Publication number
NO923739L
NO923739L NO92923739A NO923739A NO923739L NO 923739 L NO923739 L NO 923739L NO 92923739 A NO92923739 A NO 92923739A NO 923739 A NO923739 A NO 923739A NO 923739 L NO923739 L NO 923739L
Authority
NO
Norway
Prior art keywords
contrast media
contrast
complexes
multicore
atoms
Prior art date
Application number
NO92923739A
Other languages
English (en)
Other versions
NO923739D0 (no
Inventor
Arne Berg
Torsten Almen
Klaus Dieter Krautwurst
Sook-Hui Kim
Paal Rongved
Jo Klaveness
Harald Dugstad
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO923739D0 publication Critical patent/NO923739D0/no
Publication of NO923739L publication Critical patent/NO923739L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • C07F11/005—Compounds containing elements of Groups 6 or 16 of the Periodic Table compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Liquid Crystal (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Devices For Indicating Variable Information By Combining Individual Elements (AREA)
  • Steroid Compounds (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Lubricants (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Electric Propulsion And Braking For Vehicles (AREA)

Abstract

Anvendelse av flerkjernede komplekser, d.v.s. komplekser så som W_O_(/i,0)_, hvor den kompleksbundne del omfatter minst to kontrastøkende atomer, som kontrastokende midler ved medi- sinsk avbilding, spesielt røntgenavbilding.
NO92923739A 1990-03-28 1992-09-25 Kontrastmidler NO923739L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909006977A GB9006977D0 (en) 1990-03-28 1990-03-28 Compositions
PCT/EP1991/000587 WO1991014460A1 (en) 1990-03-28 1991-03-27 Contrast media

Publications (2)

Publication Number Publication Date
NO923739D0 NO923739D0 (no) 1992-09-25
NO923739L true NO923739L (no) 1992-11-06

Family

ID=10673438

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923739A NO923739L (no) 1990-03-28 1992-09-25 Kontrastmidler

Country Status (18)

Country Link
US (2) US5458869A (no)
EP (2) EP0645146A1 (no)
JP (1) JPH06507147A (no)
AT (1) ATE142508T1 (no)
AU (1) AU645796B2 (no)
CA (1) CA2079212A1 (no)
DE (1) DE69122092T2 (no)
DK (1) DK0521977T3 (no)
ES (1) ES2091323T3 (no)
FI (1) FI924297A0 (no)
GB (1) GB9006977D0 (no)
HK (1) HK219596A (no)
HU (2) HU9203086D0 (no)
LT (1) LT3535B (no)
LV (1) LV10056B (no)
NO (1) NO923739L (no)
SG (1) SG43931A1 (no)
WO (1) WO1991014460A1 (no)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9006977D0 (en) * 1990-03-28 1990-05-23 Nycomed As Compositions
WO1992017215A1 (en) 1990-03-28 1992-10-15 Nycomed Salutar, Inc. Contrast media
PH29904A (en) * 1991-03-27 1996-09-16 Salutar Inc Contrast media
US5330742A (en) * 1991-08-05 1994-07-19 Mallinckrodt Medical, Inc. Methods and compositions for magnetic resonance imaging
AU670029B2 (en) * 1991-08-05 1996-07-04 Mallinckrodt Medical, Inc. Heavy metal clusters for use as imaging agents
US5364953A (en) * 1992-11-05 1994-11-15 Mallinckrodt Medical, Inc. High relaxivity, paramagnetic, metal clusters for magnetic resonance imaging
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
US5717121A (en) * 1995-06-07 1998-02-10 Nycomed Salutar, Inc. Preparation and use of contrast agents
GB9601340D0 (en) * 1996-01-23 1996-03-27 Nycomed Salutar Inc Contrast media
JP3839059B2 (ja) * 1996-02-14 2006-11-01 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴイ Ｘ線フィルタを有するｘ線検査装置
US5804161A (en) * 1996-05-14 1998-09-08 Nycomed Salutar Inc. Contrast agents
US6537520B1 (en) 1998-03-31 2003-03-25 Bristol-Myers Squibb Pharma Company Pharmaceuticals for the imaging of angiogenic disorders
US6548663B1 (en) 1998-03-31 2003-04-15 Bristol-Myers Squibb Pharma Company Benzodiazepine vitronectin receptor antagonist pharmaceuticals
US6524553B2 (en) 1998-03-31 2003-02-25 Bristol-Myers Squibb Pharma Company Quinolone vitronectin receptor antagonist pharmaceuticals
EP1140864A2 (en) 1998-12-18 2001-10-10 Du Pont Pharmaceuticals Company Vitronectin receptor antagonist pharmaceuticals
US6794518B1 (en) 1998-12-18 2004-09-21 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6569402B1 (en) 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
CA2349501A1 (en) 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company Quinolone vitronectin receptor antagonist pharmaceuticals
US6511649B1 (en) 1998-12-18 2003-01-28 Thomas D. Harris Vitronectin receptor antagonist pharmaceuticals
US6596259B1 (en) 1998-12-22 2003-07-22 University Of Puerto Rico Metal based cubane structure contained in an octanuclear complex stable over several oxidation states and a method of producing the same
US7807137B1 (en) 1998-12-22 2010-10-05 University Of Puerto Rico Iron-based contrast agent
US6656448B1 (en) 2000-02-15 2003-12-02 Bristol-Myers Squibb Pharma Company Matrix metalloproteinase inhibitors
WO2001087354A2 (en) 2000-05-17 2001-11-22 Bristol-Myers Squibb Pharma Company Use of small molecule radioligands for diagnostic imaging
CN1386118A (zh) 2000-06-01 2002-12-18 布里斯托尔-迈尔斯斯奎布药品公司 作为Aβ蛋白产生抑制剂的被环状琥珀酸酯取代的内酰胺类化合物
HUP0400758A3 (en) 2000-11-03 2005-02-28 Bristol Myers Squibb Pharma Co Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
US7928278B2 (en) * 2001-06-12 2011-04-19 University Of Florida Research Foundation, Inc. Method and apparatus for producing near-infrared radiation
MXPA04001113A (es) 2001-08-08 2004-07-08 Bristol Myers Squibb Pharma Co Formacion de imagenes simultaneas de perfusion cardiaca y agente formador de imagenes dirigido al receptor de vitronectina.
US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
US7485283B2 (en) 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
JP4322781B2 (ja) * 2004-11-08 2009-09-02 富士フイルム株式会社 撮像装置
KR20080022588A (ko) * 2005-06-30 2008-03-11 브리스톨-마이어스 스퀴브 파마 컴퍼니 영상화제로서의 히드라지드 컨쥬게이트
US7824659B2 (en) 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
US20070098642A1 (en) * 2005-11-02 2007-05-03 General Electric Company Nanoparticle-based imaging agents for X-ray/computed tomography
US9149545B2 (en) * 2005-11-02 2015-10-06 General Electric Company Nanoparticle-based imaging agents for X-ray/computed tomography and methods for making same
AR059193A1 (es) 2006-01-31 2008-03-12 Bayer Schering Pharma Ag Modulacion de la actividad de mdl-1 para el tratamiento de enfermedades inflamatorias
WO2009110984A2 (en) 2008-02-29 2009-09-11 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
CN102088907B (zh) * 2008-07-07 2013-03-27 皇家飞利浦电子股份有限公司 K边缘成像
ES2770364T3 (es) 2009-04-15 2020-07-01 Lantheus Medical Imaging Inc Estabilización de composiciones radiofarmacéuticas utilizando ácido ascórbico
WO2011035140A1 (en) 2009-09-18 2011-03-24 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of contrast moieties to the lungs
RU2631500C2 (ru) 2010-02-08 2017-09-25 Лантеус Медикал Имаджинг, Инк. Способы и устройство для синтезирования радиофармацевтических препаратов и их промежуточных продуктов
EP2540321A1 (en) 2011-06-30 2013-01-02 Bayer Intellectual Property GmbH Bis Tridentate W3O2 Clusters for X-Ray imaging
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
EP2733148A1 (en) 2012-11-15 2014-05-21 Bayer Pharma Aktiengesellschaft Tungsten complexes with di-dentate ligands
CA2902209C (en) 2013-03-15 2025-02-04 The Regents Of The University Of California REDUCED TOXICITY PEPTIDES STIMULATING CHOLESTEROL OUTFLOW

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US468759A (en) 1892-02-09 Gabeiel a
US3763188A (en) * 1972-01-19 1973-10-02 Du Pont Spiro(1,1-polyethylenedi(oxymethyl))-3-oxetanes
US3860611A (en) * 1972-01-19 1975-01-14 Du Pont Macrocyclic polyether polyols and condensation polymers derived therefrom
US3952015A (en) * 1973-11-12 1976-04-20 Carl George Krespan Macrocyclic compounds having oxa and aza linkages in the ring and containing spirooxetane groups
US4079124A (en) * 1976-04-21 1978-03-14 Medi-Physics, Inc. Method of preparing X-ray contrast media containing ores of hafnium, tantalum and tungsten
US4176173A (en) * 1977-07-18 1979-11-27 Medi-Physics, Inc. Radiographic compositions
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4652519A (en) 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4826673A (en) 1985-01-09 1989-05-02 Mallinckrodt, Inc. Methods and compositions for enhancing magnetic resonance imaging
CA1282069C (en) 1985-09-12 1991-03-26 Damon L. Meyer Antibody complexes of hapten-modified diagnostic or therapeutic agents
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
IT1213029B (it) 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
DE3855239T2 (de) 1987-07-16 1996-10-31 Nycomed Imaging As Aminocarbonsäure und Derivate
FR2630547A1 (fr) * 1988-04-22 1989-10-27 Centre Nat Rech Scient Marquage froid de molecules de nature peptidique ou proteique
US5260050A (en) * 1988-09-29 1993-11-09 Ranney David F Methods and compositions for magnetic resonance imaging comprising superparamagnetic ferromagnetically coupled chromium complexes
EP0361960A3 (en) * 1988-09-29 1992-01-02 RANNEY, David F. Methods and compositions for magnetic resonance imaging
GB9006977D0 (en) * 1990-03-28 1990-05-23 Nycomed As Compositions
US5186923A (en) * 1990-10-10 1993-02-16 Brigham And Womens Hospital Enhancement of cellular accumulation of lipophilic cationic organometallic compounds by reduction of intramembrane potential
AU670029B2 (en) * 1991-08-05 1996-07-04 Mallinckrodt Medical, Inc. Heavy metal clusters for use as imaging agents

Also Published As

Publication number Publication date
FI924297L (fi) 1992-09-25
FI924297A7 (fi) 1992-09-25
LV10056A (lv) 1994-05-10
DE69122092T2 (de) 1997-03-06
ATE142508T1 (de) 1996-09-15
HK219596A (en) 1997-01-03
NO923739D0 (no) 1992-09-25
US5458869A (en) 1995-10-17
HUT69168A (en) 1995-08-28
JPH06507147A (ja) 1994-08-11
LTIP609A (en) 1994-12-27
FI924297A0 (fi) 1992-09-25
US5614168A (en) 1997-03-25
EP0521977A1 (en) 1993-01-13
WO1991014460A1 (en) 1991-10-03
DE69122092D1 (de) 1996-10-17
ES2091323T3 (es) 1996-11-01
CA2079212A1 (en) 1991-09-29
EP0645146A1 (en) 1995-03-29
AU645796B2 (en) 1994-01-27
HU9203086D0 (en) 1992-12-28
GB9006977D0 (en) 1990-05-23
SG43931A1 (en) 1997-11-14
AU7557891A (en) 1991-10-21
DK0521977T3 (da) 1996-09-30
LT3535B (en) 1995-11-27
EP0521977B1 (en) 1996-09-11
LV10056B (en) 1995-02-20

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