NO923964L - Antimikrobielle kinolonyllaktaner - Google Patents
Antimikrobielle kinolonyllaktanerInfo
- Publication number
- NO923964L NO923964L NO92923964A NO923964A NO923964L NO 923964 L NO923964 L NO 923964L NO 92923964 A NO92923964 A NO 92923964A NO 923964 A NO923964 A NO 923964A NO 923964 L NO923964 L NO 923964L
- Authority
- NO
- Norway
- Prior art keywords
- moiety
- reversed
- lactam
- antimicrobial
- isouronium
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title abstract 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 5
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 4
- 150000003951 lactams Chemical class 0.000 abstract 3
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- DKVNPHBNOWQYFE-UHFFFAOYSA-N carbamodithioic acid Chemical compound NC(S)=S DKVNPHBNOWQYFE-UHFFFAOYSA-N 0.000 abstract 2
- 239000012990 dithiocarbamate Substances 0.000 abstract 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 2
- FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- STIAPHVBRDNOAJ-UHFFFAOYSA-N carbamimidoylazanium;carbonate Chemical compound NC(N)=N.NC(N)=N.OC(O)=O STIAPHVBRDNOAJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- ZOOODBUHSVUZEM-UHFFFAOYSA-N ethoxymethanedithioic acid Chemical compound CCOC(S)=S ZOOODBUHSVUZEM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000002466 imines Chemical class 0.000 abstract 1
- -1 lactam compounds Chemical class 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 150000007970 thio esters Chemical class 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
- 239000012991 xanthate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51148390A | 1990-04-18 | 1990-04-18 | |
| PCT/US1991/002476 WO1991016327A1 (en) | 1990-04-18 | 1991-04-12 | Antimicrobial quinolonyl lactams |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO923964D0 NO923964D0 (no) | 1992-10-13 |
| NO923964L true NO923964L (no) | 1992-12-08 |
Family
ID=24035097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO92923964A NO923964L (no) | 1990-04-18 | 1992-10-13 | Antimikrobielle kinolonyllaktaner |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5530116A (es) |
| EP (1) | EP0525057B1 (es) |
| JP (1) | JPH05506033A (es) |
| KR (1) | KR100204987B1 (es) |
| AT (1) | ATE193890T1 (es) |
| AU (1) | AU640481B2 (es) |
| CA (1) | CA2078444A1 (es) |
| DE (1) | DE69132256T2 (es) |
| DK (1) | DK0525057T3 (es) |
| ES (1) | ES2147721T3 (es) |
| FI (1) | FI924690A7 (es) |
| IE (1) | IE911284A1 (es) |
| IL (1) | IL97897A0 (es) |
| MY (1) | MY107814A (es) |
| NO (1) | NO923964L (es) |
| NZ (1) | NZ237855A (es) |
| PT (1) | PT97403B (es) |
| SG (1) | SG47533A1 (es) |
| WO (1) | WO1991016327A1 (es) |
| ZA (1) | ZA912872B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
| US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
| US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
| EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| EP0492277A3 (en) * | 1990-12-20 | 1992-10-14 | F. Hoffmann-La Roche Ag | Cephalosporin derivatives |
| ATE150463T1 (de) * | 1991-10-01 | 1997-04-15 | Procter & Gamble Pharma | Verfahren zur herstellung von antimikrobiellen quinolonyl-lactamen |
| EP0550775A1 (en) * | 1992-01-07 | 1993-07-14 | F. Hoffmann-La Roche Ag | Cephalosporin derivatives |
| EG20543A (en) * | 1992-10-30 | 1999-07-31 | Procter & Gamble | Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones |
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| US6361560B1 (en) * | 1998-12-23 | 2002-03-26 | Anamed, Inc. | Corneal implant and method of manufacture |
| US6710086B1 (en) * | 2000-02-25 | 2004-03-23 | Medinox, Inc. | Protected forms of pharmacologically active agents and uses therefor |
| JP4792032B2 (ja) | 2004-08-13 | 2011-10-12 | シェーリング−プラウ・リミテッド | 抗生物質、トリアゾールおよびコルチコステロイドを含む薬学的処方物 |
| US8076303B2 (en) | 2005-12-13 | 2011-12-13 | Spring Bank Pharmaceuticals, Inc. | Nucleotide and oligonucleotide prodrugs |
| US10071960B1 (en) | 2017-10-05 | 2018-09-11 | King Saud University | Enaminone-grafted trithiocarbonate with anticancer and antimicrobial activity |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU33873B (en) * | 1968-08-08 | 1978-06-30 | Pliva Pharm & Chem Works | Process for the preparation of the novel 6-nalidixyl-penicillanic acid |
| AR204813A1 (es) * | 1972-05-08 | 1976-03-05 | Yamanouchi Pharma Co Ltd | Proceso para la preparacion de derivados de ampilicina |
| FR2191556A5 (en) * | 1972-06-29 | 1974-02-01 | Aries Robert | N-Acylampicillins - with broad-spectrum antibacterial activity prepd. by acylation with naphthyridine carboxylic acids |
| JPS4935392A (es) * | 1972-08-02 | 1974-04-01 | ||
| JPS5023037A (es) * | 1973-07-03 | 1975-03-12 | ||
| JPS5023036A (es) * | 1973-07-06 | 1975-03-12 | ||
| FR2243940A1 (en) * | 1973-09-17 | 1975-04-11 | Aries Robert | Antibacterial nalidixamido cephems - prepd from 7-amino cephem (salt) and nalidixic acid deriv |
| PH10309A (en) * | 1973-10-19 | 1976-11-17 | Yamanouchi Pharma Co Ltd | Penicillin derivatives |
| GB1509074A (en) * | 1974-04-05 | 1978-04-26 | Yamanouchi Pharma Co Ltd | Cephalosporin derivatives |
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| JPS5573686A (en) * | 1978-11-28 | 1980-06-03 | Mitsui Toatsu Chem Inc | Novel penicillin |
| JPS5732290A (en) * | 1980-08-06 | 1982-02-20 | Fujimoto Seiyaku Kk | Novel penicillin derivative and its preparation |
| JPS5746990A (en) * | 1980-09-03 | 1982-03-17 | Fujimoto Seiyaku Kk | Novel cephalexin derivative and its preparation |
| US4620007A (en) * | 1980-09-03 | 1986-10-28 | Bayer Aktiengesellschaft | 6-fluoro-7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid |
| US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
| JPS5746988A (en) * | 1980-09-03 | 1982-03-17 | Fujimoto Seiyaku Kk | Novel penicillin derivative and its preparation |
| WO1982001873A1 (en) * | 1980-12-05 | 1982-06-10 | Takeda Chemical Industries Ltd | 1-sulfo-2-oxoazetidine derivatives and process for their preparation |
| US4468394A (en) * | 1981-04-02 | 1984-08-28 | Eisai Co., Ltd. | Cephalosporin compounds |
| US4546176A (en) * | 1982-12-14 | 1985-10-08 | Eisai Co., Ltd. | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same |
| JPS59137482A (ja) | 1983-01-26 | 1984-08-07 | Otsuka Pharmaceut Co Ltd | ピロロ〔３，２，１，−ｉｊ〕キノリン−５−カルボン酸誘導体 |
| JPS606617A (ja) | 1983-05-09 | 1985-01-14 | Kyorin Pharmaceut Co Ltd | 抗菌性組成物 |
| GB8321677D0 (en) | 1983-08-11 | 1983-09-14 | Erba Farmitalia | Preparation of penems |
| DE3420798A1 (de) | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren |
| US4822801A (en) | 1984-07-20 | 1989-04-18 | Warner-Lambert Company | 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents |
| IE58742B1 (en) | 1984-07-20 | 1993-11-05 | Warner Lambert Co | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds |
| EP0182210B1 (en) * | 1984-11-12 | 1991-02-27 | Banyu Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| EP0187456A1 (en) | 1984-11-29 | 1986-07-16 | Ici Pharma | Cephalosporin derivatives |
| IT1215277B (it) * | 1985-05-27 | 1990-01-31 | Pomezia Roma A | Derivato chinolin-lattaminico ad attivita' antibatterica ed inibitrice delle b-lattamasi. |
| GB8626245D0 (en) * | 1985-11-27 | 1986-12-03 | Ici Pharma | Cephalosporin compounds |
| US4977154A (en) | 1985-12-12 | 1990-12-11 | Warner-Lambert Company | 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents |
| US4689325A (en) | 1985-12-23 | 1987-08-25 | Abbott Laboratories | Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives |
| US4687770A (en) | 1985-12-23 | 1987-08-18 | Abbott Laboratories | Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives |
| US4767762A (en) | 1985-12-23 | 1988-08-30 | Abbott Laboratories | Tricyclic quinoline and naphthyride antibacterials |
| JPH0791291B2 (ja) | 1985-12-30 | 1995-10-04 | イ−ライ・リリ−・アンド・カンパニ− | １−カルバセフアロスポリン抗生物質 |
| EP0230053A3 (en) | 1986-01-17 | 1988-03-30 | American Cyanamid Company | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
| EP0230946A3 (en) | 1986-01-20 | 1988-09-07 | Kyorin Pharmaceutical Co., Ltd. | Process for the preparation of quinolonecarboxylic acid derivatives |
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| EP0242789A3 (en) | 1986-04-25 | 1990-09-05 | Dainippon Pharmaceutical Co., Ltd. | Novel quinoline derivates and processes for preparation thereof |
| GB8612137D0 (en) | 1986-05-19 | 1986-06-25 | Fujisawa Pharmaceutical Co | Quinolone compounds |
| ZA874696B (en) | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
| US5147871A (en) * | 1986-07-03 | 1992-09-15 | Hoffmann La-Roche, Inc. | Anti-bacterial cephalosporin compounds |
| CA1278742C (en) | 1986-07-04 | 1991-01-08 | Mark W. Patteson | Vertically drawn shower curtain |
| IL83049A (en) | 1986-07-04 | 1991-12-12 | Chemie Linz Ag | 4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them |
| US4771055A (en) | 1986-07-28 | 1988-09-13 | Warner-Lambert Company | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids |
| GB8623211D0 (en) | 1986-09-26 | 1986-10-29 | Glaxo Group Ltd | Chemical compounds |
| NZ222047A (en) | 1986-10-08 | 1991-01-29 | Bristol Myers Co | Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents |
| DK123488A (da) | 1987-03-09 | 1988-09-10 | Otsuka Pharma Co Ltd | 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem |
| DE3711193A1 (de) | 1987-04-02 | 1988-10-13 | Bayer Ag | 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate |
| US5563138A (en) | 1987-04-16 | 1996-10-08 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| GB8709666D0 (en) | 1987-04-23 | 1987-05-28 | Beecham Group Plc | Compounds |
| US5189157A (en) * | 1987-06-16 | 1993-02-23 | Hoffmann La Roche Inc. | Antibacterial cephalosporin compounds |
| HU200917B (en) * | 1987-07-20 | 1990-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical compositions comprising quinoline or naphthyridinecarboxylic acid and tetracycline derivatives as active ingredient |
| ATE130299T1 (de) * | 1987-07-23 | 1995-12-15 | Zeneca Pharma Sa | Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische präparate. |
| GB8816519D0 (en) * | 1987-07-23 | 1988-08-17 | Ici Plc | Antibiotic compounds |
| US4923879A (en) | 1987-07-31 | 1990-05-08 | Warner-Lambert Company | 1,8-Naphthyridines and their use as antibacterial agents |
| US4851418A (en) | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
| NZ225926A (en) | 1987-09-08 | 1990-04-26 | Sterling Drug Inc | 7-pyridinyl-4-oxo-3-quinolinecarboxylic acid derivatives, and pharmaceutical compositions |
| US4839355A (en) | 1987-09-09 | 1989-06-13 | Sterling Drug Inc. | Tricyclic-pyridinylquinoline compounds, their preparation and use |
| DE3811341A1 (de) | 1987-10-09 | 1989-04-27 | Bayer Ag | In 7-stellung c-verknuepfte chinolon- und 1,8-naphthyridin-4-on-carbonsaeure und ein verfahren zu ihrer herstellung |
| IL88003A (en) | 1987-10-16 | 1992-11-15 | Dainippon Pharmaceutical Co | Quinoline derivatives,their preparation and pharmaceutical compositions containing them |
| NZ227470A (en) | 1987-12-28 | 1991-06-25 | Hoffmann La Roche | Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment |
| YU63689A (en) * | 1988-03-31 | 1991-06-30 | Hoffmann La Roche | Acyl derivatives |
| JPH01258684A (ja) * | 1988-04-07 | 1989-10-16 | Banyu Pharmaceut Co Ltd | ３‐置換キノリニウムチオメチルセファロスポリン誘導体 |
| EP0341990B1 (en) * | 1988-05-10 | 1994-11-09 | Imperial Chemical Industries Plc | Cephalosporins, process for their preparation and pharmaceutical compositions |
| AU609974B2 (en) | 1988-05-18 | 1991-05-09 | Warner-Lambert Company | Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids |
| EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| DE68928925T2 (de) * | 1988-10-24 | 1999-08-26 | Procter & Gamble Pharmaceuticals | Antimikrobielle Fluorochinolonylcephemderivate |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| DE68929227T2 (de) * | 1988-10-24 | 2001-05-31 | Procter & Gamble Pharmaceuticals, Inc. | Antimikrobielle Quinolonyllactamester |
| EP0366193A3 (en) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial quinolonyl lactams |
| US5159077A (en) * | 1989-07-21 | 1992-10-27 | Hoffmann-La Roche Inc. | Penam antibacterial compounds |
| US5162523A (en) * | 1989-07-21 | 1992-11-10 | Hoffmann-La Roche Inc. | Cephalosporin antibacterial compounds |
| ZA912279B (en) * | 1990-04-09 | 1992-02-26 | Hoffmann La Roche | Carbapenem compounds |
| US5066800A (en) * | 1990-04-27 | 1991-11-19 | Hoffmann-La Roche Inc. | Qunoline intermediates useful therein for synthesizing antibacterial compounds |
| US5112967A (en) * | 1990-04-27 | 1992-05-12 | Hoffmann-La Roches Inc. | Process for synthesizing antibacterial cephalosporin compounds |
-
1991
- 1991-04-12 ES ES91908230T patent/ES2147721T3/es not_active Expired - Lifetime
- 1991-04-12 JP JP91508348A patent/JPH05506033A/ja active Pending
- 1991-04-12 SG SG1996002674A patent/SG47533A1/en unknown
- 1991-04-12 AU AU77643/91A patent/AU640481B2/en not_active Ceased
- 1991-04-12 KR KR1019920702574A patent/KR100204987B1/ko not_active Expired - Fee Related
- 1991-04-12 DK DK91908230T patent/DK0525057T3/da active
- 1991-04-12 AT AT91908230T patent/ATE193890T1/de not_active IP Right Cessation
- 1991-04-12 EP EP91908230A patent/EP0525057B1/en not_active Expired - Lifetime
- 1991-04-12 DE DE69132256T patent/DE69132256T2/de not_active Expired - Fee Related
- 1991-04-12 CA CA002078444A patent/CA2078444A1/en not_active Abandoned
- 1991-04-12 WO PCT/US1991/002476 patent/WO1991016327A1/en not_active Ceased
- 1991-04-17 IL IL97897A patent/IL97897A0/xx unknown
- 1991-04-17 ZA ZA912872A patent/ZA912872B/xx unknown
- 1991-04-17 NZ NZ237855A patent/NZ237855A/en unknown
- 1991-04-17 IE IE128491A patent/IE911284A1/en unknown
- 1991-04-18 MY MYPI91000644A patent/MY107814A/en unknown
- 1991-04-18 PT PT97403A patent/PT97403B/pt not_active IP Right Cessation
-
1992
- 1992-10-13 NO NO92923964A patent/NO923964L/no unknown
- 1992-10-16 FI FI924690A patent/FI924690A7/fi unknown
-
1994
- 1994-12-22 US US08/361,919 patent/US5530116A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991016327A1 (en) | 1991-10-31 |
| AU7764391A (en) | 1991-11-11 |
| FI924690A0 (fi) | 1992-10-16 |
| NO923964D0 (no) | 1992-10-13 |
| FI924690A7 (fi) | 1992-10-16 |
| EP0525057A1 (en) | 1993-02-03 |
| DK0525057T3 (da) | 2000-07-31 |
| PT97403A (pt) | 1992-01-31 |
| ATE193890T1 (de) | 2000-06-15 |
| PT97403B (pt) | 1998-08-31 |
| US5530116A (en) | 1996-06-25 |
| EP0525057B1 (en) | 2000-06-14 |
| KR100204987B1 (ko) | 1999-06-15 |
| ES2147721T3 (es) | 2000-10-01 |
| JPH05506033A (ja) | 1993-09-02 |
| CA2078444A1 (en) | 1991-10-19 |
| SG47533A1 (en) | 1998-04-17 |
| EP0525057A4 (en) | 1993-04-07 |
| MY107814A (en) | 1996-06-29 |
| IE911284A1 (en) | 1991-10-23 |
| DE69132256D1 (de) | 2000-07-20 |
| NZ237855A (en) | 1994-06-27 |
| AU640481B2 (en) | 1993-08-26 |
| DE69132256T2 (de) | 2001-01-25 |
| IL97897A0 (en) | 1992-06-21 |
| ZA912872B (en) | 1992-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO923964L (no) | Antimikrobielle kinolonyllaktaner | |
| EP0366189A3 (en) | Novel antimicrobial lactam-quinolones | |
| IE41807L (en) | Biguanide salts | |
| DK0779291T3 (da) | Med heterocyclylcarbonyl substituerede benzofuranyl-urinstoffer | |
| TR200001010T2 (tr) | Ürokinaz önleyicileri olan izokinolinler. | |
| FR2539417B1 (es) | ||
| SE7603051L (sv) | Pyrimidinylkarbamider | |
| DE69302848D1 (de) | Verfahren zur Herstellung von Guanidinderivativen | |
| GB1065988A (en) | New imidazoles and process for their preparation | |
| HUP9902149A2 (hu) | Antibakteriális hatású 1-metil-karbapenem-származékok, alkalmazásuk, a vegyületeket tartalmazó gyógyászati készítmények | |
| MY117938A (en) | (2-morpholinylmethyl) benzamide derivatives | |
| DK0781272T3 (da) | Syntese af pentasubstituerede guanidiner | |
| GB1083730A (en) | Chromone and thiochromone guanylhydrazones | |
| FR2128097A1 (en) | Guanidinoalkyl-dibenzo-heterocyclics - useful as ataractics sedatives and hypotensives | |
| MY111735A (en) | Novel antimicrobial lactam-quinolones. | |
| GB1355802A (en) | Amido or imido sulphenamides | |
| GB1203544A (en) | Thiocarbamoylalkylamino-s-triazines | |
| US4010175A (en) | Thio-{62 -lactam penicillins | |
| FR2192556A5 (en) | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics | |
| FR2267309A1 (en) | Phenylamino acetamides as herbicides - prepd. by chloroacetyln of N-(2,6-disubstd-phenyl) amino acetamides | |
| NL7404919A (en) | Phenylamino acetamides as herbicides - prepd. by chloroacetyln of N-(2,6-disubstd-phenyl) amino acetamides | |
| FR2243936A1 (en) | N-s-triazinyl urea herbicides - prepd from 2-amino triazine and alkyl isocyanate or carbamoyl halide | |
| FR2188600A5 (en) | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics | |
| FR2187779A1 (en) | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics | |
| FR2192102A1 (en) | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics |