NO924522L - Optisk aktive azolforbindelser, deres fremstilling og anvendelse - Google Patents

Optisk aktive azolforbindelser, deres fremstilling og anvendelse

Info

Publication number
NO924522L
NO924522L NO92924522A NO924522A NO924522L NO 924522 L NO924522 L NO 924522L NO 92924522 A NO92924522 A NO 92924522A NO 924522 A NO924522 A NO 924522A NO 924522 L NO924522 L NO 924522L
Authority
NO
Norway
Prior art keywords
group
nitrogen
heterocyclic group
substituted
atoms
Prior art date
Application number
NO92924522A
Other languages
English (en)
Other versions
NO924522D0 (no
Inventor
Katsumi Itoh
Kenji Okonogi
Norikazu Tamura
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO924522D0 publication Critical patent/NO924522D0/no
Publication of NO924522L publication Critical patent/NO924522L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Det er beskrevet en optisk aktiv azolforbindelse med formel (I): hvor R1 og R2 uavhengig av hverandre er et hydrogen- atom, et halogenatom, en halogenalkylgruppe, en halogenalkoksygruppe eller en eventuelt substituert, nitrogenholdlg, heterocyklisk gruppe; R3 er et hydrogenatom eller en acylgruppe; O er CH eller N: -NÅ} er en nitrogenholdig, aromatisk, femleddet heterocyklisk gruppe som har minst to nabostllte nltrogenatomer som ringoppbyggende atomer som kan være substituerte, eller en aromatisk, kondensert, hetero- cyklisk gruppe Inneholdende to eller flere nitrogen- atomer som ringoppbyggende atomer som kan være substituerte; og (R) viser at karbonatomet merket med j (R) har R-konfigurasjon; forutsatt at en av R1 og R2 er i en eventuelt substituert, nitrogenholdlg, heterocyklisk j gruppe når -NÅ) er en 1H-1,2,4-trlazol-l-yl-gruppe, eller et salt derav. Forbindelsen er nyttig som anti- soppmlddel. Det er videre angitt en fremgangsmåte for fremstilling av forbindelsene.
NO92924522A 1991-11-25 1992-11-24 Optisk aktive azolforbindelser, deres fremstilling og anvendelse NO924522L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30906991 1991-11-25
JP1988892 1992-02-05
JP14551092 1992-06-05

Publications (2)

Publication Number Publication Date
NO924522D0 NO924522D0 (no) 1992-11-24
NO924522L true NO924522L (no) 1993-05-26

Family

ID=27282810

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92924522A NO924522L (no) 1991-11-25 1992-11-24 Optisk aktive azolforbindelser, deres fremstilling og anvendelse

Country Status (10)

Country Link
US (2) US5371100A (no)
EP (1) EP0548553A1 (no)
CN (2) CN1072680A (no)
AU (1) AU653082B2 (no)
CA (1) CA2083679A1 (no)
FI (1) FI925323A7 (no)
HU (1) HUT62574A (no)
NO (1) NO924522L (no)
NZ (1) NZ245226A (no)
TW (1) TW212798B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2099004B1 (es) * 1993-02-11 1998-01-16 Uriach & Cia Sa J Nuevos antifungicos activos por via oral.
ES2062941B1 (es) * 1993-03-15 1995-10-01 Uriach & Cia Sa J Nuevos derivados de azol activos por via oral.
HU212458B (en) * 1993-09-23 1996-06-28 Richter Gedeon Vegyeszet New silyloxypropane derivatives substituted with triazole or imidazole pharmaceutical compositions containing them and process for producing them
TW297813B (no) * 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd
CA2134417A1 (en) * 1993-12-22 1995-06-23 Katsumi Itoh Optically active azole derivatives, their production and use
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
CA2150533A1 (en) * 1994-05-31 1995-12-01 Katsumi Itoh Production of optically active triazole compounds and their intermediates
AU4675596A (en) * 1995-02-17 1996-09-04 Takeda Chemical Industries Ltd. Azole compounds, their production and use
TW318841B (no) 1995-02-17 1997-11-01 Takeda Pharm Industry Co Ltd
CA2275604A1 (en) * 1997-01-03 1998-07-09 Kenneth Iain Cumming Sustained release cisapride mini-tablet formulation
US6432947B1 (en) * 1997-02-19 2002-08-13 Berlex Laboratories, Inc. N-heterocyclic derivatives as NOS inhibitors
KR20010005792A (ko) 1997-03-31 2001-01-15 다케다 야쿠힌 고교 가부시키가이샤 아졸 화합물, 이의 제조 방법 및 용도
US6133485A (en) * 1998-04-15 2000-10-17 Synphar Laboratories, Inc. Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols
US6583164B1 (en) 1998-09-29 2003-06-24 Takeda Chemical Industries, Ltd. Antimycotic drug composition
IN192526B (no) * 2001-09-25 2004-04-24 Ranbaxy Lab
US7028055B2 (en) * 2002-03-22 2006-04-11 Sun Microsystems, Inc. Method and apparatus for improving transaction specification by marking application states
KR100572996B1 (ko) * 2003-08-12 2006-04-25 한국화학연구원 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법
WO2006109933A1 (en) 2005-03-30 2006-10-19 Daewoong Pharmaceutical Co., Ltd. Antifungal triazole derivatives
WO2007052943A1 (en) * 2005-10-31 2007-05-10 Daewoong Pharmaceutical Co., Ltd. Novel antifungal triazole derivatives
WO2008064311A2 (en) * 2006-11-21 2008-05-29 Viamet Pharmaceuticals, Inc. Metallo-oxidoreductase inhibitors using metal binding moieties in combination with targeting moieties
KR20080062876A (ko) * 2006-12-29 2008-07-03 주식회사 대웅제약 신규한 항진균성 트리아졸 유도체
CN102958927A (zh) 2010-05-12 2013-03-06 Abbvie公司 激酶的吲唑抑制剂
EA201490052A1 (ru) * 2011-06-23 2014-04-30 Вайамет Фармасьютикалс, Инк. Соединения, ингибирующие металлоферменты
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
EP2746262A1 (en) * 2012-12-19 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds for combating phytopathogenic fungi
AU2014222276B2 (en) * 2013-03-01 2018-06-14 Council Of Scientific & Industrial Research 1-substituted, 4-(substituted phenoxymethyl)-1,2,3-triazole compounds with antifungal properties and methods for preparation thereof
CN113416187B (zh) 2013-03-14 2024-07-19 奥斯菲治疗有限公司 促进骨生长的烷基胺骆驼蓬碱衍生物
EP2970177A1 (en) 2013-03-15 2016-01-20 Pfizer Inc. Indole compounds that activate ampk
WO2017020944A1 (en) * 2015-07-31 2017-02-09 Universite De Nantes Novel fused pyrimidinone and triazinone derivatives, their process of preparation and their therapeutic uses as antifungal and/or antiparasitic agents
CN106518922A (zh) * 2015-09-12 2017-03-22 陕西合成药业股份有限公司 一种三唑类化合物及其制备方法和用途
ES3004565T3 (en) 2018-08-14 2025-03-12 Ossifi Therapeutics Llc Pyrrolo - dipyridine compounds for the treatment of bone loss
JP7695496B2 (ja) 2018-08-14 2025-06-19 オシフィ セラピューティクス リミティド ライアビリティ カンパニー フルオロβ－カルボリン化合物
CN111217795B (zh) * 2020-02-14 2023-07-18 华侨大学 一种抗菌药物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
EP0069442B1 (en) * 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
DE3307218A1 (de) * 1983-03-02 1984-09-06 Bayer Ag, 5090 Leverkusen Substituierte diazolylalkyl-carbinole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
GB8306351D0 (en) * 1983-03-08 1983-04-13 Ici Plc Azole fungicides
US4992454A (en) * 1983-03-16 1991-02-12 Pfizer Inc. Antifungal 1,3-bis (1H-1,2,4-triazol-1-yl)-2-aryl butan-2-ols and derivatives thereof
DK159205C (da) * 1983-03-16 1991-03-04 Pfizer Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion
GB8313235D0 (en) * 1983-05-13 1983-06-22 Pfizer Ltd Antifungal agents
DE3325313A1 (de) * 1983-07-13 1985-01-31 Bayer Ag, 5090 Leverkusen Fungizide mittel, deren herstellung und verwendung
GB8412750D0 (en) * 1984-05-18 1984-06-27 Ici Plc Heterocyclic compounds
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
GB8506619D0 (en) * 1985-03-14 1985-04-17 Pfizer Ltd Triazole antifungal agents
GB8716651D0 (en) * 1987-07-15 1987-08-19 Ici Plc 2-propanol derivatives
IE903395A1 (en) * 1989-09-26 1991-04-10 Takeda Chemical Industries Ltd Triazole compounds, their production and use

Also Published As

Publication number Publication date
AU2859292A (en) 1994-03-31
EP0548553A1 (en) 1993-06-30
NO924522D0 (no) 1992-11-24
AU653082B2 (en) 1994-09-15
FI925323L (fi) 1993-05-26
CN1075143A (zh) 1993-08-11
US5495024A (en) 1996-02-27
CA2083679A1 (en) 1993-05-26
FI925323A0 (fi) 1992-11-24
CN1072680A (zh) 1993-06-02
FI925323A7 (fi) 1993-05-26
HU9203661D0 (en) 1993-03-01
NZ245226A (en) 1994-10-26
TW212798B (no) 1993-09-11
US5371100A (en) 1994-12-06
HUT62574A (en) 1993-05-28

Similar Documents

Publication Publication Date Title
DK117087A (da) Heterocycliske forbindelser, deres fremstilling oganvendelse som insekticider
GR3006247T3 (no)
MY108659A (en) Pesticidal 1-(2-pyridyl) pyrazoles
DK359289D0 (da) 4-oxoquinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf samt deres anvendelse
TWI265164B (en) 3-substituted-4-pyrimidone derivatives
NO931533L (no) Azolforbindelser, deres fremstilling og anvendelse
CA2313479A1 (en) Fungicide mixtures based on amide compounds and azoles
CO4480719A1 (es) Agentes antifungicos derivados del triazol
NO972887L (no) Piperidineddiksyrederivater anvendelige som fibrinogen-antagonistmiddel
AU546388B2 (en) ;het;-substituted-3-triazolylpropanes
ATE197304T1 (de) Triazole enthaltende antifungizide mittel
NO911149L (no) Fremgangsmaate for fremstilling av merkaptan- og merkaptoacyl-derivater.
NO871140D0 (no) Fremgangsmaate ved fremstilling av nye 1- (3-(2-(4-morfolinyl)-etoksy)-(2-dialkylaminoetoksy)-2-tienyl)-3-fenyl-propanoner og syreaddisjonssalter derav.
IL84300A (en) Herbicidal compositions containing 1-(2-(hetero)-arylsulphonylcarbanoyl)-2-pyrazoline derivatives,certain such novel compounds and their preparation
RU92004507A (ru) Оптически активные азольные соединения и способ их получения и противогрибковая композиция на их основе
JPS54163573A (en) Imidazole derivative and method
ES8601891A1 (es) Un metodo para preparar compuestos de 1, 4-dihidropiridina
MY106090A (en) Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same.
NO944888L (no) 5-(1,2,4-triazol-1-ylmetyl)-3H-isobenzofuran-1-on derivater, deres fremstilling og anvendelse som aromataseinhibitorer
MY104164A (en) Heterocyclic compounds.