NO925041L - Nye 2-sakkarinylmetylaryl- og -aryloksyacetater som er nyttige som inhibitorer for proteolytiske enzymer samt preparater og anvendelse derav - Google Patents

Nye 2-sakkarinylmetylaryl- og -aryloksyacetater som er nyttige som inhibitorer for proteolytiske enzymer samt preparater og anvendelse derav

Info

Publication number
NO925041L
NO925041L NO92925041A NO925041A NO925041L NO 925041 L NO925041 L NO 925041L NO 92925041 A NO92925041 A NO 92925041A NO 925041 A NO925041 A NO 925041A NO 925041 L NO925041 L NO 925041L
Authority
NO
Norway
Prior art keywords
succarinylmethylaryl
arryloxyacetates
preparations
inhibitors
new
Prior art date
Application number
NO92925041A
Other languages
English (en)
Other versions
NO925041D0 (no
NO303446B1 (no
Inventor
Lee Hamilton Latimer
Richard Paul Dunlap
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of NO925041D0 publication Critical patent/NO925041D0/no
Publication of NO925041L publication Critical patent/NO925041L/no
Publication of NO303446B1 publication Critical patent/NO303446B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO925041A 1991-12-30 1992-12-30 Nye 2-sakkarinylmetylaryl- og -aryloksyacetater, preparater og anvendelse derav NO303446B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81574091A 1991-12-30 1991-12-30

Publications (3)

Publication Number Publication Date
NO925041D0 NO925041D0 (no) 1992-12-30
NO925041L true NO925041L (no) 1993-07-01
NO303446B1 NO303446B1 (no) 1998-07-13

Family

ID=25218721

Family Applications (1)

Application Number Title Priority Date Filing Date
NO925041A NO303446B1 (no) 1991-12-30 1992-12-30 Nye 2-sakkarinylmetylaryl- og -aryloksyacetater, preparater og anvendelse derav

Country Status (17)

Country Link
US (3) US5385923A (no)
EP (1) EP0550112A1 (no)
JP (1) JPH05255286A (no)
AU (1) AU651746B2 (no)
CA (1) CA2086348A1 (no)
CZ (1) CZ386992A3 (no)
FI (1) FI925946A7 (no)
HU (2) HUT65736A (no)
IL (1) IL104259A (no)
MX (1) MX9207274A (no)
MY (1) MY108926A (no)
NO (1) NO303446B1 (no)
NZ (1) NZ245586A (no)
PH (1) PH30411A (no)
RU (1) RU2081871C1 (no)
SG (1) SG48025A1 (no)
TW (1) TW226016B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380737A (en) * 1989-05-04 1995-01-10 Sterling Winthrop Inc. Saccharin derivative proteolytic enzyme inhibitors
US5306818A (en) * 1990-11-01 1994-04-26 Sterling Winthrop Inc. Tetrahydro 2-saccharinylmerthyl aryl carboxylates
DE19533643A1 (de) * 1995-09-12 1997-03-13 Nycomed Arzneimittel Gmbh Neue cyclische Derivate von Benzolsulfonamiden
DE19748470A1 (de) * 1997-11-03 1999-05-06 Hoechst Schering Agrevo Gmbh Carbamoylphenylsulfonylharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren
US20090053221A1 (en) * 2006-01-17 2009-02-26 Cheung Nai-Kong V Immune response enhancing glucan
PT2445502T (pt) 2009-06-25 2017-09-22 Alkermes Pharma Ireland Ltd Compostos heterocíclicos para o tratamento de distúrbios neurológicos e psicológicos
JP5732453B2 (ja) 2009-06-25 2015-06-10 アルカーメス ファーマ アイルランド リミテッド Ｎｈ酸性化合物のプロドラッグ
EP2521711B1 (en) * 2010-01-07 2017-08-16 Alkermes Pharma Ireland Limited Quaternary ammonium salt prodrugs
NZ604423A (en) 2010-06-24 2015-01-30 Alkermes Pharma Ireland Ltd Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
ES2972387T3 (es) 2011-03-18 2024-06-12 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden ésteres de sorbitán
WO2013088255A1 (en) 2011-12-15 2013-06-20 Alkermes Pharma Ireland Limited Prodrugs of secondary amine compounds
CA2867121C (en) 2012-03-19 2021-05-25 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty acid esters
WO2013142202A1 (en) 2012-03-19 2013-09-26 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising glycerol esters
US9999670B2 (en) 2012-03-19 2018-06-19 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising benzyl alcohol
JP6654042B2 (ja) 2012-09-19 2020-02-26 アルカームス ファーマ アイルランド リミテッド 貯蔵安定性が改善された医薬組成物
WO2015102992A1 (en) 2013-12-31 2015-07-09 Saint-Gobain Abrasives, Inc. Abrasive article including shaped abrasive particles
US20150253127A1 (en) * 2014-03-04 2015-09-10 Honeywell Asca Inc. Thickness Determination of Web Product by Mid-infrared Wavelength Scanning Interferometry
AU2015231278B2 (en) 2014-03-20 2020-01-23 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
US10346168B2 (en) 2015-06-26 2019-07-09 Microsoft Technology Licensing, Llc Decoupled processor instruction window and operand buffer
AU2019230014B2 (en) 2018-03-05 2024-11-28 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3002884A (en) * 1959-04-15 1961-10-03 Rohm & Haas Horticultural process with n-halomethyl-1,2-benzisothiazolin - 3 - one-1,1-dioxides for controlling fungus diseases
US3314960A (en) * 1964-08-25 1967-04-18 American Home Prod Benzisothiazol glutarimides
FR1451417A (fr) * 1965-07-15 1966-01-07 Roussel Uclaf Nouveaux esters d'acides cycliques et leur procédé de préparation
JPS4835457A (no) * 1971-09-02 1973-05-24
US4195023A (en) * 1975-08-20 1980-03-25 Merck & Co., Inc. 2-(2-Furoyl)1,2-benzisothiazole-3-one, 2-(2-furoyl) saccharin, and 2-(2-thenoyl) saccharin
US4276298A (en) * 1978-03-24 1981-06-30 Merck & Co., Inc. 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors
US4263393A (en) * 1979-09-06 1981-04-21 Eastman Kodak Company Novel electron donor precursors and photographic element containing them
US4350752A (en) * 1980-12-29 1982-09-21 Eastman Kodak Company Photographic elements and film units containing imidomethyl blocked photographic reagents
US4363865A (en) * 1981-03-04 1982-12-14 Eastman Kodak Company Imido methyl blocked photographic dyes and dye releasing compounds
US4410618A (en) * 1982-06-11 1983-10-18 Eastman Kodak Company Blocked photographic reagents
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
US4623645A (en) * 1983-04-18 1986-11-18 Merck & Co., Inc. Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
US4659855A (en) * 1983-05-09 1987-04-21 Georgia Tech Research Corporation Aryl sulfonyl fluoride compounds
DE3617976A1 (de) * 1986-05-28 1988-01-14 Alter Sa 1,4-dihydropyridin, verfahren zu dessen herstellung und dessen verwendung in antithrombotischen medikamenten
EP0253029A1 (en) * 1986-07-10 1988-01-20 Keng-Ben Wang A distilled drinking water fountain
US5128339A (en) * 1990-11-01 1992-07-07 Sterling Winthrop Inc. Proteolytic enzyme inhibition method
KR0183397B1 (ko) * 1989-05-04 1999-05-01 존 엠. 스피나토 단백질 분해 효소 저해제로서 유용한 사카린 유도체들 및 그의 제조방법
FR2659327A1 (fr) * 1990-03-08 1991-09-13 Centre Nat Rech Scient Derives du benzisothiazolinone-1-dioxyde, utilisables comme inhibiteurs des elastases.
AU642537B2 (en) * 1990-11-01 1993-10-21 Sanofi 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
US5279758A (en) * 1991-10-22 1994-01-18 The Clorox Company Thickened aqueous cleaning compositions
AU656027B2 (en) * 1991-11-15 1995-01-19 Sanofi Saccharin derivative proteolytic enzime inhibitors
AU653279B2 (en) * 1991-12-30 1994-09-22 Sanofi Novel 2-saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
JPH07200419A (ja) * 1993-12-28 1995-08-04 Nec Corp バスインタフェース装置
DE4420271B4 (de) * 1994-06-10 2007-09-27 Robert Bosch Gmbh Zündspulensatz für eine Mehrzylinder-Brennkraftmaschine

Also Published As

Publication number Publication date
US5489604A (en) 1996-02-06
MX9207274A (es) 1993-06-01
US5783589A (en) 1998-07-21
PH30411A (en) 1997-05-09
US5385923A (en) 1995-01-31
NZ245586A (en) 1994-11-25
FI925946L (fi) 1993-07-01
AU2966992A (en) 1993-07-01
SG48025A1 (en) 1998-04-17
FI925946A0 (fi) 1992-12-30
CA2086348A1 (en) 1993-07-01
HU9204166D0 (en) 1993-04-28
CZ386992A3 (en) 1993-09-15
FI925946A7 (fi) 1993-07-01
IL104259A0 (en) 1993-05-13
NO925041D0 (no) 1992-12-30
NO303446B1 (no) 1998-07-13
RU2081871C1 (ru) 1997-06-20
TW226016B (no) 1994-07-01
HU211625A9 (en) 1995-12-28
EP0550112A1 (en) 1993-07-07
AU651746B2 (en) 1994-07-28
MY108926A (en) 1996-11-30
JPH05255286A (ja) 1993-10-05
HUT65736A (en) 1994-07-28
IL104259A (en) 1997-09-30

Similar Documents

Publication Publication Date Title
FI933277A7 (fi) Amiinidioli proteaasi-inhibiittorit
FI962315A0 (fi) Entsyymi-inhibiittorit
FI935020A7 (fi) Interleukiini-1b-proteaasi ja interleukiini-1b-proteaasin inhibiittoreita
NO925041D0 (no) Nye 2-sakkarinylmetylaryl- og aryloksyacetater som er nyttige som proteolytiske enzymerinhibitorer
FI942423A7 (fi) Sakkariinijohdannisia proteolyyttisen entsyymin inhibiittoreina
NO992492D0 (no) Benzamidoaldehyder og deres anvendelse som cystein-protease-inhibitorer
DK70491A (da) Heterocykliske peptidrenininhibitorer, fremgangsmaade til fremstilling deraf og farmaceutisk middel indeholdende en saadan inhibitor samt anvendelse deraf
DK0889036T3 (da) HIV-proteaseinhibitorer
NO305316B1 (no) Nye substituerte 1H-imidazoler og farmas°ytiske preparater inneholdende disse
FI961857A7 (fi) Matriksin metalloproteaasien inhibiittorit
FI894541A0 (fi) Aids-laekemedel baserade pao hiv-proteasinhibitorer.
NO975742D0 (no) Reversible cysteinproteasehemmere
AU1266495A (en) Cysteine protease inhibitors containing heterocyclic leaving groups
FI925787A7 (fi) Proeteolyyttisten entsyymien sakkariinijohdannaisinhibiittoreita
NO922673D0 (no) Nye hiv proteaseinhibitorer
MY104021A (en) Benzamide protease inhibitors.
DK326989D0 (da) Alminoalkylaminocarbonylaminodiolaminosyrederivater og deres anvendelse som renininhibitorer
FI960482A7 (fi) Matriksin metalloproteaasien inhibiittorit
FI962488L (fi) HIV:n proteaasin inhibiittoreita
FI895962A7 (fi) Proteaasi-inhibiittorit
FI962021L (fi) 5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina
NO954321L (no) 4-aryl-4-hydroksy-tetrahydropyraner og 3-aryl-3-hydroksy-tetrahydrofuraner som 5-lipoksygenase-inhibitorer
MX9206568A (es) Derivados de sacarina inhibidores de enzimas proteoliticas.
NO308745B1 (no) Nye, polycykliske forbindelser samt preparater inneholdende disse
TR199501429A2 (tr) Matriks metaloproteaz inhibitörlerinin yerine gecen 4-biarilpentanoik asitleri ve türevleri