NO930738L - Nye cyklosporinger, fremgangsmaate for deres fremstilling og farmasoeytiske preparater derav - Google Patents

Nye cyklosporinger, fremgangsmaate for deres fremstilling og farmasoeytiske preparater derav

Info

Publication number
NO930738L
NO930738L NO93930738A NO930738A NO930738L NO 930738 L NO930738 L NO 930738L NO 93930738 A NO93930738 A NO 93930738A NO 930738 A NO930738 A NO 930738A NO 930738 L NO930738 L NO 930738L
Authority
NO
Norway
Prior art keywords
procedures
preparation
pharmaceutical preparations
new cycle
cycle tracks
Prior art date
Application number
NO93930738A
Other languages
English (en)
Other versions
NO310685B1 (no
NO930738D0 (no
Inventor
Johann J Boelsterli
Marcel K Eberle
Reto Naef
Trevor G Payne
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO930738D0 publication Critical patent/NO930738D0/no
Publication of NO930738L publication Critical patent/NO930738L/no
Publication of NO310685B1 publication Critical patent/NO310685B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Gasification And Melting Of Waste (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19930738A 1992-03-02 1993-03-01 Nye cyklosporiner, fremgangsmåte for deres fremstilling, anvendelsen herav for fremstilling av medikamenter samtfarmasöytiske preparater inneholdende disse NO310685B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929204466A GB9204466D0 (en) 1992-03-02 1992-03-02 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
NO930738D0 NO930738D0 (no) 1993-03-01
NO930738L true NO930738L (no) 1993-09-03
NO310685B1 NO310685B1 (no) 2001-08-13

Family

ID=10711333

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19930738A NO310685B1 (no) 1992-03-02 1993-03-01 Nye cyklosporiner, fremgangsmåte for deres fremstilling, anvendelsen herav for fremstilling av medikamenter samtfarmasöytiske preparater inneholdende disse

Country Status (26)

Country Link
US (1) US5643870A (no)
EP (1) EP0577544B1 (no)
JP (1) JP3382656B2 (no)
KR (1) KR100256988B1 (no)
CN (1) CN1037104C (no)
AT (1) ATE146484T1 (no)
AU (1) AU667072B2 (no)
CA (1) CA2090634C (no)
CZ (1) CZ285421B6 (no)
DE (1) DE69306670T2 (no)
DK (1) DK0577544T3 (no)
ES (1) ES2096262T3 (no)
FI (1) FI111729B (no)
GB (1) GB9204466D0 (no)
GR (1) GR3022539T3 (no)
HU (1) HU214028B (no)
IL (1) IL104891A (no)
MX (1) MX9301129A (no)
MY (1) MY106921A (no)
NO (1) NO310685B1 (no)
NZ (1) NZ247031A (no)
PL (1) PL174816B1 (no)
RU (1) RU2131883C1 (no)
SK (1) SK279529B6 (no)
TW (1) TW264472B (no)
ZA (1) ZA931491B (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639852A (en) * 1994-09-01 1997-06-17 Wisconsin Alumni Research Foundation Immunostimulatory agents
CN1130373C (zh) * 1996-09-13 2003-12-10 诺瓦蒂斯有限公司 [3'-脱氧-3'-氧代-MeBmt]'环孢菌素制备方法
ZA9711732B (en) 1996-12-31 1998-12-28 Quadrant Holdings Cambridge Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery
US20030220234A1 (en) 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
AU750245B2 (en) 1997-10-08 2002-07-11 Aurinia Phamaceuticals Inc. Deuterated cyclosporine analogs and their use as immunomodulating agents
PL342742A1 (en) * 1998-03-06 2001-07-02 Novartis Ag Emulsion-type pre-concentrates containing cyclosporin or macrolyde
US6784156B2 (en) 2001-03-05 2004-08-31 Enanta Pharmaceuticals, Inc. Cyclosporins for the treatment of respiratory diseases
DE60208180T2 (de) * 2001-04-20 2006-08-17 Debiopharm S.A. Modifiziertes, als medikamentvorstufe anwendbares cyclosporin und dessen verwendung
US20030087813A1 (en) * 2001-10-12 2003-05-08 Or Yat Sun Cyclosporin analogs for the treatment of lung diseases
US6809077B2 (en) * 2001-10-12 2004-10-26 Enanta Pharmaceuticals, Inc. Cyclosporin analogs for the treatment of autoimmune diseases
ES2310604T3 (es) * 2001-10-19 2009-01-16 Isotechnika, Inc. Mezclas de analogos de ciclosporinas y su uso como agentes inmunomoduladores.
WO2003033526A2 (en) * 2001-10-19 2003-04-24 Isotechnika Inc. Synthesis of cyclosporin analogs
US7012065B2 (en) * 2003-02-07 2006-03-14 Enanta Pharmaceuticals, Inc. Cyclosporins for the treatment of immune disorders
JP2006524232A (ja) * 2003-03-17 2006-10-26 アルバニー モレキュラー リサーチ インコーポレーティッド 新規サイクロスポリン
US20040266669A1 (en) * 2003-06-20 2004-12-30 Wu Frank X. H. Cyclosporin derivatives for the treatment of immune disorders
JP2006014722A (ja) 2004-06-02 2006-01-19 Keio Gijuku 遺伝子マーカー及びその利用
JP2008514701A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
EP1804823A4 (en) * 2004-09-29 2010-06-09 Amr Technology Inc NEW CYCLOSPORIN ANALOGUE AND ITS PHARMACEUTICAL APPLICATIONS
US7361636B2 (en) * 2004-10-06 2008-04-22 Amr Technology, Inc. Cyclosporin alkynes and their utility as pharmaceutical agents
US7696167B2 (en) * 2004-11-22 2010-04-13 Astellas Pharma Inc. Cyclic peptide compound
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US8435544B2 (en) 2007-10-08 2013-05-07 Lux Biosciences, Inc. Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors
BRPI0911709A2 (pt) * 2008-07-30 2017-06-20 Isotechnika Labs Inc composto, processo para a produção de um composto, composição farmacêutica e método de tratar uma doença mediada a ciclofilina em um mamífero
WO2010144194A1 (en) 2009-06-09 2010-12-16 Lux Biosciences, Inc. Topical drug delivery systems for ophthalmic use
US20130267460A1 (en) * 2010-09-16 2013-10-10 The Johns Hopkins University Methods of Inhibiting Alphavirus Replication and Treating Alphavirus Infection
JP6144627B2 (ja) 2010-12-15 2017-06-07 コントラヴィア ファーマシューティカルズ、インク. アミノ酸1および3で修飾されたシクロスポリン類似体分子
CN105076117B (zh) * 2014-10-31 2017-08-25 北京林业大学 一种种子抗老化剂及其制备方法
KR20170000243U (ko) 2015-07-09 2017-01-18 (주)하나피앤씨 배관연결용 플랜지 기구
US9981041B2 (en) * 2016-08-23 2018-05-29 Ira Jason Salzman Ophthalmic lubricating spray
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
US4764503A (en) * 1986-11-19 1988-08-16 Sandoz Ltd. Novel cyclosporins
EP0283801A3 (en) * 1987-03-27 1990-05-30 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US4798823A (en) * 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
GB8717300D0 (en) * 1987-07-22 1987-08-26 Nat Res Dev Cyclosporins
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
DE3840354A1 (de) * 1988-11-30 1990-06-07 Hoechst Ag Benzolsulfonamid-derivate und verfahren zu ihrer herstellung
JPH04502328A (ja) * 1988-12-05 1992-04-23 ザ・トラステイーズ・オブ・コロンビア・ユニヴアーシテイ・イン・ザ・シテイ・オブ・ニユー・ヨーク シクロスポリンaの新規誘導体、それに対する抗体及びその使用
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
GB8916901D0 (en) * 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US5202310A (en) * 1990-06-06 1993-04-13 Levy Gary A Cyclosporine metabolites
ATE148469T1 (de) * 1990-11-02 1997-02-15 Sandoz Ag Zyklosporine

Also Published As

Publication number Publication date
FI111729B (fi) 2003-09-15
IL104891A0 (en) 1993-07-08
PL174816B1 (pl) 1998-09-30
DE69306670D1 (de) 1997-01-30
MX9301129A (es) 1994-07-29
KR930019692A (ko) 1993-10-18
GB9204466D0 (en) 1992-04-15
US5643870A (en) 1997-07-01
KR100256988B1 (ko) 2000-05-15
DK0577544T3 (da) 1997-04-01
FI930912L (fi) 1993-09-03
MY106921A (en) 1995-08-30
EP0577544B1 (en) 1996-12-18
HU214028B (en) 1997-12-29
NO310685B1 (no) 2001-08-13
TW264472B (no) 1995-12-01
HUT64567A (en) 1994-01-28
PL297902A1 (en) 1993-09-06
SK14093A3 (en) 1993-10-06
RU2131883C1 (ru) 1999-06-20
CZ285421B6 (cs) 1999-08-11
CZ30393A3 (en) 1994-02-16
ES2096262T3 (es) 1997-03-01
IL104891A (en) 1997-04-15
ATE146484T1 (de) 1997-01-15
NZ247031A (en) 1995-05-26
DE69306670T2 (de) 1997-07-03
GR3022539T3 (en) 1997-05-31
FI930912A0 (fi) 1993-03-01
CA2090634A1 (en) 1993-09-03
AU667072B2 (en) 1996-03-07
NO930738D0 (no) 1993-03-01
CN1037104C (zh) 1998-01-21
CA2090634C (en) 2005-12-13
EP0577544A1 (en) 1994-01-05
CN1076453A (zh) 1993-09-22
JP3382656B2 (ja) 2003-03-04
JPH07252296A (ja) 1995-10-03
SK279529B6 (sk) 1998-12-02
HU9300418D0 (en) 1993-05-28
ZA931491B (en) 1994-09-02
AU3387293A (en) 1993-09-09

Similar Documents

Publication Publication Date Title
NO930738D0 (no) Nye cyklosporinger, fremgangsmaate for deres fremstilling og farmasoeytiske preparater derav
GEP20012413B (en) Novel Substituted Cyclic Amino Acids as Pharmaceutical Agents
GEP20012578B (en) (54) Heteroaryl Succinamides, Pharmaceutical Compositions Containing the Same and Methods for Treatment of the Diseases Caused by Metalloproteinase Activity
MX9803753A (es) Acidos alfa-iminohidroxamicos y -carboxilicos n-sustituidos ciclicos y heterociclicos.
TR199801180T2 (xx) Aneljestik etkiye sahip yeni bile�ikler.
GEP20043324B (en) Purine Derivatives
TR199900661T2 (xx) Cilt enfeksiyonlar�n�n tedavisi amac�yla 1-hidroksi-2-piridonlar�n kullan�m�
TR199900770T2 (xx) Nazal poliplerin tedavisinde bir H+, K+-ATPase'�n kullan�lmas�.
CA2163197A1 (en) Tri(platinum) complexes
SE9402880D0 (sv) New peptide derivatives
DK0743940T3 (da) Nye forbindelser med analgetisk og local-anæstetisk virkning
MXPA02011533A (es) Nuevas formulaciones de alfa-2,4-disulfofenil-n-terc-butilnitrona.
TR199801184T2 (xx) Analjezik tesirli yeni bile�ikler.
NO995838L (no) Nye heteroetynylenforbindelser og farmasoeytiske og kosmetiske preparater inneholdende de samme
FR2674434B1 (fr) Nouvelle composition pharmaceutique a base de taurine pour l'administration par inhalation.
GR3001862T3 (en) Pharmaceutical preparation for tinea pedis
NO894720L (no) Farmasoeytisk aktivt protein.
DK0613375T3 (da) Farmaceutiske lysinholdige polypeptidpræparater og anvendelse deraf
GR3004113T3 (no)
ATE96449T1 (de) Adamantyl enthaltende tripeptide, deren derivate und hydrochloride, deren herstellung und benutzung.
FR2672888B1 (fr) Nouvelles urees et thiourees, leur preparation et leur application en therapeutique.
DE69413302D1 (de) Palau'amin: eine pharmakologisch aktive Verbindung aus einem Schwamm
EP0621789A4 (en) Pharmaceutical pentapeptide compositions and methods of use thereof.
IT1264428B1 (it) Composizioni farmaceutiche per il trattamento della psoriasi
ATE199557T1 (de) Calcium-komplex von (4r)-4-bis(carboxy- kappa.o)methyl amino-.kappa.n-6,9-bis (carboxy-

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees