NO932033L - 7-substituerte-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyreforbindelser - Google Patents
7-substituerte-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyreforbindelserInfo
- Publication number
- NO932033L NO932033L NO93932033A NO932033A NO932033L NO 932033 L NO932033 L NO 932033L NO 93932033 A NO93932033 A NO 93932033A NO 932033 A NO932033 A NO 932033A NO 932033 L NO932033 L NO 932033L
- Authority
- NO
- Norway
- Prior art keywords
- group
- substituted
- quinoline
- dihydro
- oxo
- Prior art date
Links
- -1 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds Chemical class 0.000 title abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000001607 1,2,3-triazol-1-yl group Chemical group [*]N1N=NC([H])=C1[H] 0.000 abstract 1
- 125000003626 1,2,4-triazol-1-yl group Chemical group [*]N1N=C([H])N=C1[H] 0.000 abstract 1
- XXJGBENTLXFVFI-UHFFFAOYSA-N 1-amino-methylene Chemical group N[CH2] XXJGBENTLXFVFI-UHFFFAOYSA-N 0.000 abstract 1
- ZMDQWHCTODNNLT-UHFFFAOYSA-N 2h-1,2-benzoxazine-3-carboxylic acid Chemical class C1=CC=C2ONC(C(=O)O)=CC2=C1 ZMDQWHCTODNNLT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62171690A | 1990-12-05 | 1990-12-05 | |
| PCT/CA1991/000435 WO1992010492A1 (en) | 1990-12-05 | 1991-12-05 | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds useful as antibacterial agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO932033L true NO932033L (no) | 1993-06-03 |
| NO932033D0 NO932033D0 (no) | 1993-06-03 |
| NO305479B1 NO305479B1 (no) | 1999-06-07 |
Family
ID=24491336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO932033A NO305479B1 (no) | 1990-12-05 | 1993-06-03 | AnalogifremgangsmÕte for fremstilling av 1-cyklopropyl-6-fluor-7-[3(S)-(1,2,3-triazol-1-yl)-pyrrolidin-1-yl]-1,4-dihydro-4-okso-1,8-naftyridin-3-karboksylsyre |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0561850B1 (no) |
| JP (1) | JPH06507149A (no) |
| KR (1) | KR100196440B1 (no) |
| AT (1) | ATE194612T1 (no) |
| CA (1) | CA2099591C (no) |
| DE (1) | DE69132314T2 (no) |
| FI (1) | FI932596A7 (no) |
| HU (2) | HUT64058A (no) |
| NO (1) | NO305479B1 (no) |
| NZ (1) | NZ240883A (no) |
| WO (1) | WO1992010492A1 (no) |
| ZA (1) | ZA919601B (no) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5342846A (en) * | 1990-12-05 | 1994-08-30 | Synphar Laboratories, Inc. | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents |
| US5221676A (en) * | 1992-02-06 | 1993-06-22 | Warner-Lambert Company | 7-substituted quinolones and naphthyridones as antibacterial agents |
| KR960003616B1 (ko) * | 1992-07-23 | 1996-03-20 | 재단법인 한국화학연구소 | 우수한 항균작용을 갖는 신규한 피리돈 카르복실산 유도체 및 그의 제조방법 |
| TW252107B (no) * | 1993-08-27 | 1995-07-21 | Hokuriku Pharmacetical Co Ltd | |
| KR19980701625A (ko) * | 1995-01-24 | 1998-06-25 | 이토 마사노리 | 퀴놀린카르본산유도체 |
| BR0011236A (pt) * | 1999-06-02 | 2002-03-05 | Warner Lambert Co | Amino heterociclos úteis como agentes farmacêuticos |
| US6821969B2 (en) | 2001-02-13 | 2004-11-23 | Pharmacia & Upjohn Company | Thioxazinoquinolones as antiviral agents |
| CA2835835C (en) | 2011-05-13 | 2019-04-02 | Array Biopharma Inc. | Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as trka kinase inhibitors |
| SG2014004162A (en) | 2011-08-31 | 2014-03-28 | Otsuka Pharma Co Ltd | Quinolone compound |
| CA2936886A1 (en) | 2014-02-27 | 2015-08-03 | Merck Patent Gmbh | Heterocyclic compounds as nav channel inhibitors and uses thereof |
| GB201708606D0 (en) | 2017-05-30 | 2017-07-12 | King S College London | Antibiotic resistance breakers |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58742B1 (en) * | 1984-07-20 | 1993-11-05 | Warner Lambert Co | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds |
| DE3519286A1 (de) * | 1985-05-30 | 1986-12-04 | Bayer Ag, 5090 Leverkusen | 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| AU5123690A (en) * | 1989-03-13 | 1990-09-13 | Bristol-Myers Squibb Company | 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents |
| NO177302C (no) * | 1989-03-16 | 1995-08-23 | Esteve Labor Dr | Analogifremgangsmåte til fremstilling av terapeutisk aktive substituerte azetidinylkinolon(naftyridon)karboksylsyrederivater |
-
1991
- 1991-12-05 AT AT91920890T patent/ATE194612T1/de not_active IP Right Cessation
- 1991-12-05 DE DE69132314T patent/DE69132314T2/de not_active Expired - Fee Related
- 1991-12-05 WO PCT/CA1991/000435 patent/WO1992010492A1/en not_active Ceased
- 1991-12-05 JP JP4500232A patent/JPH06507149A/ja active Pending
- 1991-12-05 CA CA002099591A patent/CA2099591C/en not_active Expired - Fee Related
- 1991-12-05 EP EP91920890A patent/EP0561850B1/en not_active Expired - Lifetime
- 1991-12-05 KR KR1019930701694A patent/KR100196440B1/ko not_active Expired - Fee Related
- 1991-12-05 HU HU931648D patent/HUT64058A/hu unknown
- 1991-12-05 HU HU931648A patent/HU9301648D0/hu unknown
- 1991-12-05 ZA ZA919601A patent/ZA919601B/xx unknown
- 1991-12-05 NZ NZ240883A patent/NZ240883A/en unknown
-
1993
- 1993-06-03 NO NO932033A patent/NO305479B1/no unknown
- 1993-06-07 FI FI932596A patent/FI932596A7/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU9301648D0 (en) | 1993-09-28 |
| CA2099591A1 (en) | 1992-06-06 |
| NZ240883A (en) | 1994-09-27 |
| AU666296B2 (en) | 1996-02-08 |
| EP0561850A1 (en) | 1993-09-29 |
| ATE194612T1 (de) | 2000-07-15 |
| AU9021091A (en) | 1992-07-08 |
| JPH06507149A (ja) | 1994-08-11 |
| FI932596A7 (fi) | 1993-08-04 |
| NO305479B1 (no) | 1999-06-07 |
| FI932596A0 (fi) | 1993-06-07 |
| HUT64058A (en) | 1993-11-29 |
| EP0561850B1 (en) | 2000-07-12 |
| DE69132314T2 (de) | 2000-12-14 |
| NO932033D0 (no) | 1993-06-03 |
| ZA919601B (en) | 1992-10-28 |
| WO1992010492A1 (en) | 1992-06-25 |
| KR100196440B1 (ko) | 1999-06-15 |
| CA2099591C (en) | 2002-11-12 |
| DE69132314D1 (de) | 2000-08-17 |
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