NO932636L - Benzimidazoler, medikamenter inneholdende disse forbindelser, og fremgangsmaate for deres fremstilling - Google Patents

Benzimidazoler, medikamenter inneholdende disse forbindelser, og fremgangsmaate for deres fremstilling

Info

Publication number
NO932636L
NO932636L NO932636A NO932636A NO932636L NO 932636 L NO932636 L NO 932636L NO 932636 A NO932636 A NO 932636A NO 932636 A NO932636 A NO 932636A NO 932636 L NO932636 L NO 932636L
Authority
NO
Norway
Prior art keywords
benzimidazoles
compounds
preparation
methods
drugs containing
Prior art date
Application number
NO932636A
Other languages
English (en)
Other versions
NO932636D0 (no
NO300772B1 (no
Inventor
Norbert Hauel
Uwe Ries
Van Jacques Meel
Wolfgang Wienen
Michael Entzeroth
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO932636D0 publication Critical patent/NO932636D0/no
Publication of NO932636L publication Critical patent/NO932636L/no
Publication of NO300772B1 publication Critical patent/NO300772B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO932636A 1992-07-22 1993-07-21 Benzimidazoler, medikamenter inneholdende disse forbindelser, og anvendelse av disse NO300772B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4224133A DE4224133A1 (de) 1992-07-22 1992-07-22 Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Publications (3)

Publication Number Publication Date
NO932636D0 NO932636D0 (no) 1993-07-21
NO932636L true NO932636L (no) 1994-01-24
NO300772B1 NO300772B1 (no) 1997-07-21

Family

ID=6463804

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932636A NO300772B1 (no) 1992-07-22 1993-07-21 Benzimidazoler, medikamenter inneholdende disse forbindelser, og anvendelse av disse

Country Status (20)

Country Link
EP (1) EP0581166A1 (no)
JP (1) JPH06179659A (no)
KR (1) KR940005584A (no)
CN (1) CN1050122C (no)
AU (1) AU675433B2 (no)
CA (1) CA2100927A1 (no)
CZ (1) CZ144993A3 (no)
DE (1) DE4224133A1 (no)
FI (1) FI933284A7 (no)
HU (1) HUT64955A (no)
IL (1) IL106408A (no)
MX (1) MX9304424A (no)
NO (1) NO300772B1 (no)
NZ (1) NZ248217A (no)
PL (1) PL172929B1 (no)
RU (1) RU2126401C1 (no)
SG (1) SG43083A1 (no)
SK (1) SK73293A3 (no)
TW (1) TW229207B (no)
ZA (1) ZA93529B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4233590A1 (de) * 1992-10-06 1994-04-07 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4304455A1 (de) * 1993-02-15 1994-08-18 Bayer Ag Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate
DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE19503160A1 (de) * 1995-02-01 1996-08-08 Bayer Ag Verwendung von Phenylcyclohexylcarbonsäureamiden
EP0882718B1 (en) * 1995-12-28 2005-08-31 Fujisawa Pharmaceutical Co., Ltd. Benzimidazole derivatives
TW453999B (en) * 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
RU2185171C2 (ru) * 1999-06-25 2002-07-20 Институт нефтехимии и катализа АН РБ и УНЦ РАН Способ профилактики реокклюзий при операциях на магистральных сосудах
HU222773B1 (hu) * 2000-04-21 2003-10-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás egy ismert tetrazolszármazék előállítására
WO2005011736A1 (ja) * 2003-07-30 2005-02-10 Tohoku Techno Arch Co., Ltd. アルツハイマー病の予防および/または治療剤
DE102004060699A1 (de) * 2004-12-16 2006-06-22 Ratiopharm Gmbh Verfahren zur Herstellung von Candesartan
RU2427574C2 (ru) * 2009-07-16 2011-08-27 Государственное образовательное учреждение высшего профессионального образования "Астраханский государственный университет" (АГУ) Моногидрохлориды и натриевые соли таутомерных 5(6)-алкоксикарбониламинопроизводных 2-арил-1-гидроксибензимидазол-3-оксида с высокой противогрибковой активностью и способ их получения
CN101891735B (zh) * 2009-11-25 2012-07-18 北京理工大学 联苯磺胺异噁唑类化合物、合成方法及用途
CN101921265B (zh) * 2009-11-25 2012-07-04 北京理工大学 联苯酰胺四唑类化合物、合成方法及用途
CA2852964A1 (en) * 2011-11-03 2013-05-10 F. Hoffmann-La Roche Ag Bicyclic piperazine compounds
CN105820125B (zh) * 2015-01-09 2018-12-07 北京中医药大学 一种用于治疗高血压的化合物及其制备方法和用途
CN105384729B (zh) * 2015-07-09 2019-02-19 天津青松华药医药有限公司 替米沙坦酯类衍生物及其制备方法与应用
CN106749220B (zh) * 2017-01-18 2019-08-06 东华大学 一种6’-取代苯并咪唑-4-取代甲基吲哚衍生物及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
WO1991012001A1 (en) * 1990-02-13 1991-08-22 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted benzyl element
RU1836357C (ru) * 1990-07-23 1993-08-23 Др.Карл Томэ ГмбХ Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами
SI9210098B (sl) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate

Also Published As

Publication number Publication date
PL172929B1 (pl) 1997-12-31
JPH06179659A (ja) 1994-06-28
HU9302115D0 (en) 1993-10-28
IL106408A (en) 1998-08-16
KR940005584A (ko) 1994-03-21
NZ248217A (en) 1996-06-25
CN1083812A (zh) 1994-03-16
AU4209493A (en) 1994-01-27
MX9304424A (es) 1994-01-31
FI933284A0 (fi) 1993-07-21
CZ144993A3 (en) 1994-03-16
CN1050122C (zh) 2000-03-08
FI933284A7 (fi) 1994-01-23
IL106408A0 (en) 1993-11-15
CA2100927A1 (en) 1994-01-23
NO932636D0 (no) 1993-07-21
EP0581166A1 (de) 1994-02-02
RU2126401C1 (ru) 1999-02-20
HUT64955A (en) 1994-03-28
SG43083A1 (en) 1997-10-17
NO300772B1 (no) 1997-07-21
AU675433B2 (en) 1997-02-06
TW229207B (no) 1994-09-01
SK73293A3 (en) 1994-04-06
PL299754A1 (en) 1994-03-21
DE4224133A1 (de) 1994-01-27
ZA93529B (en) 1995-01-23

Similar Documents

Publication Publication Date Title
DK0502314T3 (da) Benzimidazoler, lægemidler indeholdende disse forbindelser og fremgangsmåder til deres fremstilling
NO924027D0 (no) Heterobiarylderivater, legemidler inneholdende disse forbindelser, og fremgangsmaate for deres fremstilling
DK0612741T3 (da) Cykliske derivater, lægemidler indeholdende disse forbindelser og fremgangsmåde til deres fremstilling
NO933248D0 (no) Cykliske urinstoffderivater, legemidler inneholdende disse forbindelser, og fremgangsm}te for deres fremstilling
NO930517D0 (no) Benzimidazolylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
NO932120D0 (no) Bifenylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
FI954105A7 (fi) Uusia 4-aminopyridiinejä, niiden valmistusmenetelmä sekä näitä yhdisteitä sisältäviä lääkkeitä
NO922940D0 (no) Fem-leddete heterocykliske forbindelser, fremgangsmaate for deres fremstilling og legemidler inneholdende dem
NO934501D0 (no) Karboksylsyrederivater, legemidler inneholdende disse forbindelser, og fremgangsmaat e for deres fremstilling
DK0567966T3 (da) Cykliske aminoderivater, fremgangsmåder til deres fremstilling og lægemidler indeholdende disse forbindelser
NO307707B1 (no) Spiroazabicykliske forbindelser, farmasøytisk preparat inneholdende slike forbindelser og anvendelse derav
NO985368L (no) Substituerte imidazolidinderivater, deres fremstilling, deres anvendelse og farmas°ytiske preparater inneholdende forbindelsene
NO972881D0 (no) Piperazinderivater, legemidler som inneholder disse, anvendelse derav og fremgangsmåte for deres fremstilling
NO932636D0 (no) Benzimidazoler, medikamenter inneholdende disse forbindelser, og fremgangsmaate for deres fremstilling
DK610284D0 (da) 2-phenyl-imidazolderivater, deres fremstilling og laegemidler indeholdende disse forbindelser
DK162491D0 (da) Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
DK435588A (da) Aralkylaminoalkoxyphenylderivater, fremgangsmaade til deres fremstilling og midler indeholdende disse
DK166279C (da) 3,4-dihydro-2h-benzooebaapyranderivater, deres fremstilling og laegemidler indeholdende disse forbindelser
DK0838469T3 (da) 10,13,15-trioxatricyclo(9.2.1 9.6)-pentadecanon-derivater, fremgangsmåde til deres fremstilling og lægemidler indeholdende disse forbindelser
NO931342D0 (no) Benzimidazoler, medisinske preparater inneholdende disse,og fremgangsmaate for deres fremstilling
DK155292D0 (da) Kemiske forbindelser, deres fremstilling og anvendelse
NO930796D0 (no) Glykopeptidderivater, fremgangsmaate for deres fremstilling og farmasoeytiske midler inneholdende disse
DK102990D0 (da) Thieno-triazolodiazepinderivater, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
DK304090A (da) Glycerolderivater, fremgangsmaade til deres fremstilling og terapeutiske praeparater indeholdende disse
NO940130D0 (no) Benzimidazolderivater, fremgangsmaate for deres fremstilling og te rapeutisk anvendelse derav

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2001