NO933042L - Nmda-antagonister - Google Patents

Nmda-antagonister

Info

Publication number
NO933042L
NO933042L NO93933042A NO933042A NO933042L NO 933042 L NO933042 L NO 933042L NO 93933042 A NO93933042 A NO 93933042A NO 933042 A NO933042 A NO 933042A NO 933042 L NO933042 L NO 933042L
Authority
NO
Norway
Prior art keywords
nmda antagonists
nmda
antagonists
sulfanimide
directed
Prior art date
Application number
NO93933042A
Other languages
English (en)
Other versions
NO180485B (no
NO933042D0 (no
NO180485C (no
Inventor
Boyd L Harrison
Bruce M Baron
David M Stemerick
Ian A Mcdonald
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO933042D0 publication Critical patent/NO933042D0/no
Publication of NO933042L publication Critical patent/NO933042L/no
Publication of NO180485B publication Critical patent/NO180485B/no
Publication of NO180485C publication Critical patent/NO180485C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO933042A 1991-02-27 1993-08-26 NMDA-antagonister NO180485C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66178091A 1991-02-27 1991-02-27
US70000491A 1991-05-14 1991-05-14
PCT/US1992/001093 WO1992015565A1 (en) 1991-02-27 1992-02-11 Nmda antagonists

Publications (4)

Publication Number Publication Date
NO933042D0 NO933042D0 (no) 1993-08-26
NO933042L true NO933042L (no) 1993-08-26
NO180485B NO180485B (no) 1997-01-20
NO180485C NO180485C (no) 1997-04-30

Family

ID=27098383

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933042A NO180485C (no) 1991-02-27 1993-08-26 NMDA-antagonister

Country Status (14)

Country Link
EP (1) EP0573562B1 (no)
JP (1) JP3465794B2 (no)
KR (1) KR100224045B1 (no)
AT (1) ATE137225T1 (no)
AU (1) AU660969B2 (no)
CA (1) CA2104297C (no)
DE (1) DE69210229T2 (no)
DK (1) DK0573562T3 (no)
ES (1) ES2089511T3 (no)
FI (1) FI103202B (no)
GR (1) GR3019772T3 (no)
HU (1) HU217425B (no)
NO (1) NO180485C (no)
WO (1) WO1992015565A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5318985A (en) * 1991-12-20 1994-06-07 Merrell Dow Pharmaceuticals Inc. Potentiation of NMDA antagonists
EP0647137B1 (en) * 1992-06-22 2008-08-13 The Regents Of The University Of California Glycine receptor antagonists and the use thereof
US5475007A (en) * 1993-05-28 1995-12-12 The Regents Of The University Of California 1,2,3,4-tetrahydroquinoline-2,3,4-trione-3 or 4-oximes and the use thereof
CA2175458C (en) * 1993-11-29 1999-03-02 Boyd L. Harrison Novel benzenesulfonylimine derivatives as inhibitors of il-1 action
NZ276570A (en) * 1993-11-29 2001-02-23 Merrell Pharma Inc 4-benzenesulphonyliminoquinolin-(and chromen- and thiochromen-)2-carboxylic acid ester and amide derivatives; use in the manufacture of medicaments
CA2788656A1 (en) 2010-02-16 2011-08-25 Pfizer Inc. (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719102D0 (en) * 1987-08-12 1987-09-16 Merck Sharp & Dohme Therapeutic agents
EP0386839B1 (en) * 1989-03-08 1997-01-15 Merck Sharp & Dohme Ltd. Tetrahydroquinoline derivatives useful for neurodegenerative disorders
NZ233641A (en) * 1989-05-16 1992-07-28 Merrell Dow Pharma Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions

Also Published As

Publication number Publication date
HU9302433D0 (en) 1993-11-29
NO180485B (no) 1997-01-20
ATE137225T1 (de) 1996-05-15
HUT67301A (en) 1995-03-28
NO933042D0 (no) 1993-08-26
JP3465794B2 (ja) 2003-11-10
CA2104297A1 (en) 1992-08-28
DK0573562T3 (da) 1996-05-13
AU1532092A (en) 1992-10-06
GR3019772T3 (en) 1996-07-31
NO180485C (no) 1997-04-30
FI933762L (fi) 1993-08-26
HU217425B (hu) 2000-01-28
FI103202B1 (fi) 1999-05-14
EP0573562A1 (en) 1993-12-15
FI933762A0 (fi) 1993-08-26
KR100224045B1 (ko) 1999-10-15
CA2104297C (en) 2003-05-27
ES2089511T3 (es) 1996-10-01
FI103202B (fi) 1999-05-14
WO1992015565A1 (en) 1992-09-17
KR930703257A (ko) 1993-11-29
AU660969B2 (en) 1995-07-13
EP0573562B1 (en) 1996-04-24
DE69210229T2 (de) 1996-11-14
JPH06505746A (ja) 1994-06-30
DE69210229D1 (de) 1996-05-30

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees