NO933341L - Fordindelser mot kreft - Google Patents

Fordindelser mot kreft

Info

Publication number: NO933341L
Authority: NO; Norway
Prior art keywords: carbon atoms; alkyl; alkoxy; hydroxy; halogen
Prior art date: 1991-03-19

Application number

NO933341A

Other languages

English (en)

Norwegian (no)

Other versions

NO933341D0 (no

Inventor

Graham Michael Fraser Bisset

Ann Lesley Jackman

Duncan Ian Jodrell

Original Assignee

British Tech Group

Ici Plc

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-19

Filing date

1993-09-20

Publication date

1993-11-18

1993-09-20 Application filed by British Tech Group, Ici Plc, Ici Ltd filed Critical British Tech Group

1993-09-20 Publication of NO933341D0 publication Critical patent/NO933341D0/no

1993-11-18 Publication of NO933341L publication Critical patent/NO933341L/no

Links

206010028980 Neoplasm Diseases 0.000 title abstract 2
201000011510 cancer Diseases 0.000 title abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 12
125000000217 alkyl group Chemical group 0.000 abstract 9
125000003545 alkoxy group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 4
150000002367 halogens Chemical class 0.000 abstract 4
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
-1 hydroxy- Chemical class 0.000 abstract 3
125000001424 substituent group Chemical group 0.000 abstract 3
125000005236 alkanoylamino group Chemical group 0.000 abstract 2
125000004103 aminoalkyl group Chemical group 0.000 abstract 2
150000008574 D-amino acids Chemical group 0.000 abstract 1
108010016626 Dipeptides Proteins 0.000 abstract 1
125000000729 N-terminal amino-acid group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000000539 amino acid group Chemical group 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000005242 carbamoyl alkyl group Chemical group 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
125000003790 chinazolinyl group Chemical group 0.000 abstract 1
125000004966 cyanoalkyl group Chemical group 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000005358 mercaptoalkyl group Chemical group 0.000 abstract 1
125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

NO933341A 1991-03-19 1993-09-20 Fordindelser mot kreft NO933341L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919105771A GB9105771D0 (en)	1991-03-19	1991-03-19	Anti-cancer compounds
PCT/GB1992/000476 WO1992016512A1 (fr)	1991-03-19	1992-03-18	Composes anticancereux

Publications (2)

Publication Number	Publication Date
NO933341D0 NO933341D0 (no)	1993-09-20
NO933341L true NO933341L (no)	1993-11-18

Family

ID=10691801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO933341A NO933341L (no)	1991-03-19	1993-09-20	Fordindelser mot kreft

Country Status (18)

Country	Link
US (1)	US5444061A (fr)
EP (1)	EP0509643A1 (fr)
JP (1)	JPH06505974A (fr)
AU (1)	AU655970B2 (fr)
CA (1)	CA2106583A1 (fr)
CZ (1)	CZ195393A3 (fr)
FI (1)	FI934106A7 (fr)
GB (2)	GB9105771D0 (fr)
HU (1)	HUT67177A (fr)
IE (1)	IE920853A1 (fr)
IL (1)	IL101281A0 (fr)
MX (1)	MX9201183A (fr)
NO (1)	NO933341L (fr)
NZ (1)	NZ242023A (fr)
SK (1)	SK100993A3 (fr)
TW (1)	TW203608B (fr)
WO (1)	WO1992016512A1 (fr)
ZA (1)	ZA921985B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9205907D0 (en) *	1992-03-18	1992-04-29	Cancer Res Inst Royal	Anti-cancer compounds
GB9223352D0 (en) *	1992-11-06	1992-12-23	Ici Plc	Tricyclic compounds
GB9408936D0 (en) *	1994-05-05	1994-06-22	Cancer Res Inst	Anti-cancer compounds
CZ293323B6 (cs) *	1995-08-30	2004-04-14	G. D. Searle & Co.	Meta-guanidinové, močovinové, thiomočovinové nebo azacyklické deriváty aminobenzoové kyseliny jako antagonisty integrinů
GB9904275D0 (en)	1999-02-24	1999-04-21	Cancer Res Campaign Tech	Anti-cancer compounds
US7671200B2 (en) *	1999-10-27	2010-03-02	Cytokinetics, Inc.	Quinazolinone KSP inhibitors
US7230000B1 (en) *	1999-10-27	2007-06-12	Cytokinetics, Incorporated	Methods and compositions utilizing quinazolinones
US6545004B1 (en)	1999-10-27	2003-04-08	Cytokinetics, Inc.	Methods and compositions utilizing quinazolinones
AU2003213092A1 (en) *	2002-02-15	2003-09-09	Smithkline Beecham Corporation	Syntheses of quinazolinones
EP1503993A4 (fr) *	2002-05-09	2006-05-03	Cytokinetics Inc	Composes, compositions et procedes
JP2005530785A (ja) *	2002-05-09	2005-10-13	サイトキネティクス・インコーポレーテッド	化合物、組成物、及び方法
EP1513820A4 (fr)	2002-05-23	2006-09-13	Cytokinetics Inc	Composes, compositions et procedes
EP1556357A4 (fr) *	2002-06-14	2006-09-13	Cytokinetics Inc	Composes, compositions et procedes
US20030236430A1 (en) *	2002-06-21	2003-12-25	Allen David Robert	Preparation of protected amino acids
US7211580B2 (en) *	2002-07-23	2007-05-01	Cytokinetics, Incorporated	Compounds, compositions, and methods
AU2003262747A1 (en) *	2002-08-21	2004-03-11	Cytokinetics, Inc.	Compounds, compositions, and methods
JP2006501306A (ja) *	2002-09-30	2006-01-12	サイトキネティクス・インコーポレーテッド	化合物、組成物および方法
WO2005041888A2 (fr) *	2003-11-03	2005-05-12	Cytokinetics, Inc.	Composes, compositions et methodes
US20050148593A1 (en) *	2003-11-07	2005-07-07	Gustave Bergnes	Compounds, compositions, and methods
JP2007513154A (ja) *	2003-12-08	2007-05-24	サイトキネティクス・インコーポレーテッド	化合物、組成物及び方法
CN101646670A (zh)	2007-04-11	2010-02-10	默克阿泼洛发股份公司	18f-标记的叶酸酯
EP3186242B1 (fr)	2014-08-29	2021-10-06	Tes Pharma S.r.l.	Inhibiteurs de la semialdéhyde décarboxylase de l'acide alpha-amino-bêta-carboxymuconique
EP3846793B1 (fr)	2018-09-07	2024-01-24	PIC Therapeutics, Inc.	Inhibiteurs d'eif4e et leurs utilisations
MX2022010944A (es)	2020-03-03	2022-11-09	Pic Therapeutics Inc	Inhibidores del factor de iniciacion de traduccion eucariotica 4e (eif4e) y sus usos.
JP2024532276A (ja)	2021-08-25	2024-09-05	ピクセラピューティクス，インコーポレイテッド	ｅＩＦ４Ｅ阻害剤及びその使用
TW202315621A (zh)	2021-08-25	2023-04-16	美商皮克醫療公司	Ｅｉｆ４ｅ抑制劑及其用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0031237B1 (fr) *	1979-12-19	1984-10-17	National Research Development Corporation	Dérivés de la quinazoline, procédés pour leur préparation, compositions les contenant et leur utilisation comme agents anticancéreux
GB8513754D0 (en) *	1985-05-31	1985-07-03	Jones T R	Anti-cancer quinazoline derivatives
US4746659A (en) *	1985-12-30	1988-05-24	Sri International	Diastereomers of 10-alkyl-10-deazaminopterins and process for preparing the same
US5187167A (en) *	1986-03-27	1993-02-16	Imperial Chemical Industries Plc	Pharmaceutical compositions comprising quinazolin-4-one derivatives
GB8607683D0 (en) *	1986-03-27	1986-04-30	Ici Plc	Anti-tumor agents
GB8625019D0 (en) *	1986-10-18	1986-11-19	Wellcome Found	Compounds
GB8707053D0 (en) *	1987-03-25	1987-04-29	Ici Plc	Anti-tumour agents
US4767761A (en) *	1987-11-04	1988-08-30	Dana-Farber Cancer Institute, Inc.	Ornithine derivatives and their use as methotrexate-resistant cell inhibitors
GB8727737D0 (en) *	1987-11-26	1987-12-31	Ici Plc	Antitumour agents
GB8809978D0 (en) *	1988-04-27	1988-06-02	Ici Plc	Anti-tumour agents
US5252573A (en) *	1988-12-15	1993-10-12	Imperial Chemical Industries Plc	Anti-tumor agents
GB8829296D0 (en) *	1988-12-15	1989-01-25	Ici Plc	Anti-tumour compounds
US4996207A (en) *	1990-01-18	1991-02-26	Nair Madhavan G	Three new non-polyglutamatable deazaaminopterins
EP0457529B1 (fr) *	1990-05-17	1995-08-09	SMITH & NEPHEW UNITED, INC.	Film électroconducteur et astrigent et composition filmogène à utiliser pour l'épiderme
IL98167A0 (en) *	1990-05-30	1992-06-21	Ici Plc	Anti-tumour quinazoline derivatives,processes for their preparation and pharmaceutical compositions comprising them

1991
- 1991-03-19 GB GB919105771A patent/GB9105771D0/en active Pending
1992
- 1992-03-18 HU HU9302636A patent/HUT67177A/hu unknown
- 1992-03-18 EP EP92302304A patent/EP0509643A1/fr not_active Withdrawn
- 1992-03-18 SK SK1009-93A patent/SK100993A3/sk unknown
- 1992-03-18 WO PCT/GB1992/000476 patent/WO1992016512A1/fr not_active Ceased
- 1992-03-18 GB GB9205906A patent/GB2253849B/en not_active Expired - Fee Related
- 1992-03-18 JP JP4506050A patent/JPH06505974A/ja active Pending
- 1992-03-18 US US08/122,473 patent/US5444061A/en not_active Expired - Fee Related
- 1992-03-18 CA CA002106583A patent/CA2106583A1/fr not_active Abandoned
- 1992-03-18 IE IE085392A patent/IE920853A1/en unknown
- 1992-03-18 ZA ZA921985A patent/ZA921985B/xx unknown
- 1992-03-18 IL IL101281A patent/IL101281A0/xx unknown
- 1992-03-18 MX MX9201183A patent/MX9201183A/es unknown
- 1992-03-18 AU AU13716/92A patent/AU655970B2/en not_active Expired - Fee Related
- 1992-03-19 CZ CS931953A patent/CZ195393A3/cs unknown
- 1992-04-27 TW TW081103276A patent/TW203608B/zh active
- 1992-05-18 NZ NZ242023A patent/NZ242023A/en unknown
1993
- 1993-09-20 NO NO933341A patent/NO933341L/no unknown
- 1993-09-20 FI FI934106A patent/FI934106A7/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
IE920853A1 (en)	1992-09-23
MX9201183A (es)	1994-06-30
ZA921985B (en)	1993-09-20
GB9205906D0 (en)	1992-04-29
HUT67177A (en)	1995-02-28
FI934106A7 (fi)	1993-11-18
JPH06505974A (ja)	1994-07-07
HU9302636D0 (en)	1993-12-28
AU1371692A (en)	1992-10-21
SK100993A3 (en)	1994-08-10
AU655970B2 (en)	1995-01-19
EP0509643A1 (fr)	1992-10-21
GB9105771D0 (en)	1991-05-01
US5444061A (en)	1995-08-22
NO933341D0 (no)	1993-09-20
GB2253849B (en)	1995-01-18
CA2106583A1 (fr)	1992-09-20
IL101281A0 (en)	1992-11-15
NZ242023A (en)	1993-12-23
GB2253849A (en)	1992-09-23
TW203608B (fr)	1993-04-11
WO1992016512A1 (fr)	1992-10-01
CZ195393A3 (en)	1994-07-13
FI934106A0 (fi)	1993-09-20

Publication	Publication Date	Title
US4248883A (en)	1981-02-03	1-(3-Mercapto-2-methylpropanoyl)prolyl amino acid derivatives and salts thereof, processes for their preparation, and pharmaceutical compositions containing such compounds
CA2140598A1 (fr)	1995-07-28	Derives de la prolineamide
US4692458A (en)	1987-09-08	Anti-hypertensive agents
KR870007205A (ko)	1987-08-17	펩티딜아미노디올
KR890013035A (ko)	1989-09-21	인돌로카르바졸 유도체와 그 제조방법 및 그들을 함유하는 약제조성물
DE69427800D1 (de)	2001-08-30	Methode zur Hemmung der Endometriose
MX9201183A (es)	1994-06-30	Quinazolinas, procedimiento para su obtencion y composicion farmaceutica que las contiene.
KR870007204A (ko)	1987-08-17	작용화 펩티딜 아미노디올 및-트리올
SE8802790D0 (sv)	1988-08-02	Tripeptider med immunostimulerande och metastasforhindrande verkan
KR950703554A (ko)	1995-09-20	피페라진 유도체 및 그의 염(piperazine derivatives and salts thereof)
RU2001113268A (ru)	2003-09-27	Сочетанная терапия рибавирином и интерфероном α для удаления определяемой рнк вируса гепатита с у пациентов с хроническим гепатитом с
GB9215844D0 (en)	1992-09-09	Novel compounds
FR2610934B1 (fr)	1989-05-05	Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR870007164A (ko)	1987-08-17	모노술팍탐
KR930007914A (ko)	1993-05-20	제1위치에 에테르 또는 티오에테르 그룹을 함유하는 프탈라진 및 이의 제조방법
DK384485D0 (da)	1985-08-23	1,6-naphthyridinderivater med kardilaterende virkning
HRP920948A2 (en)	1997-10-31	Nitratoalkanecarbone acid derivatives, process for the preparation thereof, the use of the same and drugs containing them
KR830008998A (ko)	1983-12-16	N-치환된-아미노-아미노산의 제조방법
KR950702544A (ko)	1995-07-29	비페닐메탄 유도체 및 이를 함유하는 약제
EA199800464A1 (ru)	1999-02-25	Синергическая иммуносупрессорная композиция, содержащая 2,2'-би-1н-пиррольное соединение
US4734420A (en)	1988-03-29	Anti-hypertensive agents
EA199800085A1 (ru)	1998-08-27	Способ лечения боли висцерального происхождения, способ лечения воспалительного колита
RU93057568A (ru)	1996-12-27	Производные хиназолина, способ их получения, способ лечения
RU2001121195A (ru)	2003-06-27	((Аминоиминометил)амино)алканкарбоксидамиды и их применение в терапии
SU1433958A1 (ru)	1988-10-30	2-Оксо-4-(о-дифторметилтиофенил)-5-метоксикарбонил-6-метил-1,2,3,4-тетрагидропиримидин, обладающий коронарорасшир ющим действием