NO934489L - Kompleksdanner for gallesyre - Google Patents

Kompleksdanner for gallesyre

Info

Publication number
NO934489L
NO934489L NO934489A NO934489A NO934489L NO 934489 L NO934489 L NO 934489L NO 934489 A NO934489 A NO 934489A NO 934489 A NO934489 A NO 934489A NO 934489 L NO934489 L NO 934489L
Authority
NO
Norway
Prior art keywords
elements
matrix elements
bile acid
elongate
complexing agent
Prior art date
Application number
NO934489A
Other languages
English (en)
Other versions
NO934489D0 (no
Inventor
Larry Wayne Steffier
Robert Lee Albright
Eric Cylde Peters
Original Assignee
Rohm & Haas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohm & Haas filed Critical Rohm & Haas
Publication of NO934489D0 publication Critical patent/NO934489D0/no
Publication of NO934489L publication Critical patent/NO934489L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Glass Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

En kompleksdanner for gallesyre omfatter en for- nettet polymermatriks av a) langstrakte maktrikselementer, b) en effektiv mengde tverrbindende matrikselementer som er fornettet med de langstrakte matrikselementer og som gjør kompleksdanneren uløselig i vann, samt c) grenelementer som er bundet til de langstrakte matriks- elementer. De langstrakte matrikselementer og grenelementene er dannet av polymeriske kjeder av repeterende enheter med strukturformelen _(-CH2-C-)- c=o l R3-N A l R, og de tverrbindende matrikselementer har formelen eller FfCH-CH2-)- ^10 og utgjør seter for binding av gallesyrekonjugater til kompleksdanneren. Farmasøytiske preparater som inneholder kompleks- danneren er omtalt.
NO934489A 1992-12-21 1993-12-09 Kompleksdanner for gallesyre NO934489L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/994,026 US5451397A (en) 1992-12-21 1992-12-21 Bile acid sequestrant

Publications (2)

Publication Number Publication Date
NO934489D0 NO934489D0 (no) 1993-12-09
NO934489L true NO934489L (no) 1994-06-22

Family

ID=25540215

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934489A NO934489L (no) 1992-12-21 1993-12-09 Kompleksdanner for gallesyre

Country Status (16)

Country Link
US (1) US5451397A (no)
EP (1) EP0606742B1 (no)
JP (1) JPH06192129A (no)
KR (1) KR940013515A (no)
CN (1) CN1103871A (no)
AT (1) ATE160364T1 (no)
AU (1) AU5219993A (no)
BR (1) BR9305160A (no)
CA (1) CA2111631A1 (no)
DE (1) DE69315319T2 (no)
DK (1) DK0606742T3 (no)
ES (1) ES2109445T3 (no)
FI (1) FI935496L (no)
HU (1) HUT65692A (no)
NO (1) NO934489L (no)
PH (1) PH30119A (no)

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US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US6203785B1 (en) * 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
GB2329334A (en) * 1997-09-18 1999-03-24 Reckitt & Colmann Prod Ltd Cholesterol-lowering agents
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
GB2373438A (en) * 2001-02-10 2002-09-25 Reckitt & Colmann Prod Ltd Cholesterol lowering compositions
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
JP7905355B2 (ja) * 2020-12-07 2026-08-14 アラータ ライフ サイエンス インコーポレイテッド 反応性マイクロ粒子、および官能性ヒドロゲル粒子を調製するためのそれらの使用

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FR1224301A (fr) * 1958-02-27 1960-06-23 Ciba Geigy Procédé de polymérisation de composés oléfiniques basiques par polymérisation dans le 1,2-dichloréthane
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US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
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Also Published As

Publication number Publication date
DE69315319D1 (de) 1998-01-02
US5451397A (en) 1995-09-19
HUT65692A (en) 1994-07-28
AU5219993A (en) 1994-06-30
KR940013515A (ko) 1994-07-15
PH30119A (en) 1996-12-27
HU9303476D0 (en) 1994-04-28
FI935496A7 (fi) 1994-06-22
EP0606742B1 (en) 1997-11-19
DE69315319T2 (de) 1998-04-23
CN1103871A (zh) 1995-06-21
ES2109445T3 (es) 1998-01-16
BR9305160A (pt) 1994-07-26
JPH06192129A (ja) 1994-07-12
CA2111631A1 (en) 1994-06-22
FI935496L (fi) 1994-06-22
NO934489D0 (no) 1993-12-09
FI935496A0 (fi) 1993-12-08
EP0606742A1 (en) 1994-07-20
ATE160364T1 (de) 1997-12-15
DK0606742T3 (da) 1998-07-27

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