NO940312L - Nytt bisheterocyklisk derivat eller salt derav - Google Patents

Nytt bisheterocyklisk derivat eller salt derav

Info

Publication number
NO940312L
NO940312L NO940312A NO940312A NO940312L NO 940312 L NO940312 L NO 940312L NO 940312 A NO940312 A NO 940312A NO 940312 A NO940312 A NO 940312A NO 940312 L NO940312 L NO 940312L
Authority
NO
Norway
Prior art keywords
salt
pharmaceutically acceptable
phenylene
represent
different
Prior art date
Application number
NO940312A
Other languages
English (en)
Other versions
NO940312D0 (no
Inventor
Kunihiro Niigata
Takumi Takahashi
Takashi Yoneda
Osamu Noshiro
Reiko Koike
Akiyoshi Shimaya
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO940312D0 publication Critical patent/NO940312D0/no
Publication of NO940312L publication Critical patent/NO940312L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

En bisheterosyklisk forbind- else representert ved generell formel (D O¿(?)¿R' (I) L:¿ O¿(37¿ R! stereoisomerer derav, tautomerer derav, et farmasøytisk akseptabelt salt eller et farmasøytisk akseptabelt solvat der- av, et farmasøytisk preparat innehold- ende denne, og en fremgangsmåte for fremstilling derav. I formel (I) kan R1 og R2 være like eller forskjellige fra hverandre, og hver betegner (II) Y1 -CH: (II) eller R3 betegner hydrogen eller en beskytt- ende gruppe, X, Y1 og Y2 kan være like eller forskjellige fra hverandre, og hver betegner oksygen eller svovel, B1 og B2 betegner hver fenylen, B3 betegner fenylen, naftylen, sykloheksylen eller furo[3,2-b]furanylen, L1 og L2 betegner hver -(0)n-A-, n betegner O eller l, og A betegner en enkeltbinding eller lavere alkylen, forutsatt at når n er l, betegner A alkylen, og oksygenatomet av hver av L1 og L2 er bundet til B3. De ovenfor angitte forbindelser er anvend- bare som et hypoglykemisk legemiddel basert på aktiviteten for å øke insu- linsensitivitet.
NO940312A 1991-07-30 1994-01-28 Nytt bisheterocyklisk derivat eller salt derav NO940312L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21432691 1991-07-30
JP9355392 1992-03-19
PCT/JP1992/000954 WO1993003021A1 (fr) 1991-07-30 1992-07-28 Nouveau derive bisheterocyclique ou son sel

Publications (2)

Publication Number Publication Date
NO940312D0 NO940312D0 (no) 1994-01-28
NO940312L true NO940312L (no) 1994-03-17

Family

ID=26434883

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940312A NO940312L (no) 1991-07-30 1994-01-28 Nytt bisheterocyklisk derivat eller salt derav

Country Status (14)

Country Link
US (1) US5508296A (no)
EP (1) EP0597102B1 (no)
KR (1) KR100204938B1 (no)
AT (1) ATE175409T1 (no)
AU (1) AU663514B2 (no)
CA (1) CA2114001A1 (no)
DE (1) DE69228122T2 (no)
DK (1) DK0597102T3 (no)
ES (1) ES2128355T3 (no)
FI (1) FI940419A0 (no)
HU (1) HUT70421A (no)
NO (1) NO940312L (no)
TW (1) TW202445B (no)
WO (1) WO1993003021A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179246C (no) * 1991-11-20 1996-09-04 Sankyo Co Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav
TW268952B (no) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
KR0173145B1 (ko) * 1993-04-07 1999-02-01 고바야시 유키오 티아졸리딘 유도체 및 이를 함유하는 약학적 조성물
ES2129123T3 (es) * 1993-04-30 1999-06-01 Yamanouchi Pharma Co Ltd Nuevo derivado de bisoxadiazolidina.
WO2001079150A1 (en) * 2000-04-17 2001-10-25 Novo Nordisk A/S New compounds, their preparation and use
US6509374B2 (en) 2000-04-17 2003-01-21 Novo Nordisk A/S Compounds, their preparation and use
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
DE60115132T2 (de) * 2000-04-21 2006-07-06 Pfizer Products Inc., Groton Thyroid-Rezeptorliganden
DE10130718A1 (de) * 2001-06-26 2003-01-02 Merck Patent Gmbh Kohlenhydratderivate
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
WO2003033453A1 (en) * 2001-10-17 2003-04-24 Novo Nordisk A/S Dicarboxylic acid derivatives, their preparation and therapeutical use
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
WO2004056740A1 (en) * 2002-12-20 2004-07-08 Novo Nordisk A/S Dicarboxylic acid derivatives as ppar-agonists
JP2007508382A (ja) * 2003-10-14 2007-04-05 イーライ リリー アンド カンパニー Ｐｐａｒモジュレータとしてのフェノキシエーテル誘導体
CN115433121B (zh) * 2022-08-24 2023-11-28 东南大学 一种用于制备透明聚酰亚胺的脂肪族二胺单体的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8910639D0 (en) * 1989-05-09 1989-06-21 Beecham Group Plc Novel compounds
GB8919434D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
CA2086606A1 (en) * 1990-07-03 1992-01-04 Kunihiro Niigata Bisheterocyclic compound

Also Published As

Publication number Publication date
DE69228122D1 (de) 1999-02-18
EP0597102B1 (en) 1999-01-07
EP0597102A4 (en) 1994-05-25
DK0597102T3 (da) 1999-08-09
ATE175409T1 (de) 1999-01-15
FI940419A7 (fi) 1994-01-28
DE69228122T2 (de) 1999-06-24
EP0597102A1 (en) 1994-05-18
CA2114001A1 (en) 1993-02-18
TW202445B (no) 1993-03-21
WO1993003021A1 (fr) 1993-02-18
NO940312D0 (no) 1994-01-28
KR100204938B1 (ko) 1999-06-15
HUT70421A (en) 1995-10-30
US5508296A (en) 1996-04-16
AU663514B2 (en) 1995-10-12
AU2346592A (en) 1993-03-02
ES2128355T3 (es) 1999-05-16
HU9400244D0 (en) 1994-05-30
FI940419A0 (fi) 1994-01-28

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